Oxidative DNA damage as a marker of aging in WI-38 human fibroblasts

Experimental Gerontology

Volumn 37, Issue 5, 2002, Pages 647-656

  Wolf, Federica I ^a   Torsello, Angela ^a   Covacci, Valeria ^a   Fasanella, Silvia ^a   Montanari, Micaela ^a   Boninsegna, Alma ^a   Cittadini, Achille ^a  

^a CATHOLIC UNIVERSITY   (Italy)

Author keywords

8 OHdG; 8 OHdG, 8 hydroxy 2 deoxyguanosine; Cell cycle; DNA strand breaks; H2O2; OD, optical density; p21; PDs, population doublings; SA galactosidase; SA galactosidase, senescence associated galactosidase (pH 6); THF, tetrahydrofurane

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; BETA GALACTOSIDASE; HYDROGEN PEROXIDE; PROTEIN P21;

AGING; ARTICLE; CELL CULTURE; CELL CYCLE; COMET ASSAY; CONTROLLED STUDY; DIPLOIDY; DNA DAMAGE; FIBROBLAST; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LONG TERM EXPOSURE; OXIDATIVE STRESS; PRIORITY JOURNAL; SENESCENCE;

BETA-GALACTOSIDASE; BIOLOGICAL MARKERS; CELL AGING; CELL CYCLE; CELL LINE; DEOXYGUANOSINE; DNA DAMAGE; DNA REPAIR; FIBROBLASTS; HUMANS; HYDROGEN PEROXIDE; OXIDATION-REDUCTION; OXIDATIVE STRESS;

EID: 0036125867     PISSN: 05315565     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0531-5565(02)00005-0     Document Type: Article

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