ARK5 suppresses the cell death induced by nutrient starvation and death receptors via inhibition of caspase 8 activation, but not by chemotherapeutic agents or UV irradiation

Oncogene

Volumn 22, Issue 40, 2003, Pages 6177-6182

  Suzuki, Atsushi ^a   Kusakai, Gen Ichi ^a   Kishimoto, Atsuhiro ^a   Lu, Jie ^a   Ogura, Tsutomu ^a   Esumi, Hiroyasu ^a  

^a NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

Author keywords

Akt; ARK5; Caspase 8; Cell survival; HepG2

Indexed keywords

CAMPTOTHECIN; CASPASE 8; DOXORUBICIN; GLUCOSE; PROTEIN ARK5; PROTEIN BID; PROTEIN SERINE THREONINE KINASE; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG;

ARTICLE; CELL DEATH; CELL STIMULATION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; SIGNAL TRANSDUCTION; STARVATION; ULTRAVIOLET IRRADIATION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CARCINOMA, HEPATOCELLULAR; CARRIER PROTEINS; CASP8 AND FADD-LIKE APOPTOSIS REGULATING PROTEIN; CASPASES; CELL SURVIVAL; ENZYME ACTIVATION; GLUCOSE; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIGANDS; LIVER NEOPLASMS; MEMBRANE GLYCOPROTEINS; MODELS, BIOLOGICAL; NECROSIS; PROTEIN KINASES; RECEPTORS, TUMOR NECROSIS FACTOR; REPRESSOR PROTEINS; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA; ULTRAVIOLET RAYS;

VECTORS;

EID: 0142120469     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1206899     Document Type: Article

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