메뉴 건너뛰기




Volumn 12, Issue REV. ISS. 2, 2003, Pages

DNA methylation and Rett syndrome

Author keywords

[No Author keywords available]

Indexed keywords

CYTOSINE; DNA; METHYL CPG BINDING PROTEIN;

EID: 0141925713     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/ddg286     Document Type: Review
Times cited : (105)

References (78)
  • 1
    • 0027141519 scopus 로고
    • Number of CpG islands and genes in human and mouse
    • Antequera, F. and Bird, A. (1993) Number of CpG islands and genes in human and mouse. Proc. Natl Acad. Sci. USA, 90, 11995-11999.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 11995-11999
    • Antequera, F.1    Bird, A.2
  • 3
    • 0033601073 scopus 로고    scopus 로고
    • Methylation-induced repression - Belts, braces, and chromatin
    • Bird, A.P. and Wolffe, A.P. (1999) Methylation-induced repression - belts, braces, and chromatin. Cell, 99, 451-454.
    • (1999) Cell , vol.99 , pp. 451-454
    • Bird, A.P.1    Wolffe, A.P.2
  • 4
    • 0037372003 scopus 로고    scopus 로고
    • Epigenetic regulation of gene expression: How the genome integrates intrinsic and environmental signals
    • Jaenisch, R. and Bird, A. (2003) Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat. Genet., 33 (Suppl.), 245-254.
    • (2003) Nat. Genet. , vol.33 , Issue.SUPPL. , pp. 245-254
    • Jaenisch, R.1    Bird, A.2
  • 5
    • 0037370442 scopus 로고    scopus 로고
    • Activation of the early B-cell-specific mb-1 (Ig-alpha) gene by Pax-5 is dependent on an unmethylated Ets binding site
    • Maier, H., Colbert, J., Fitzsimmons, D., Clark, D.R. and Hagman, J. (2003) Activation of the early B-cell-specific mb-1 (Ig-alpha) gene by Pax-5 is dependent on an unmethylated Ets binding site. Mol. Cell. Biol., 23, 1946-1960.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 1946-1960
    • Maier, H.1    Colbert, J.2    Fitzsimmons, D.3    Clark, D.R.4    Hagman, J.5
  • 6
    • 0034713375 scopus 로고    scopus 로고
    • Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene
    • Bell, A.C. and Felsenfeld, G. (2000) Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene. Nature, 405, 482-485.
    • (2000) Nature , vol.405 , pp. 482-485
    • Bell, A.C.1    Felsenfeld, G.2
  • 7
    • 0031792779 scopus 로고    scopus 로고
    • Identification and characterization of a family of mammalian methyl-CpG binding proteins
    • Hendrich, B. and Bird, A. (1998) Identification and characterization of a family of mammalian methyl-CpG binding proteins. Mol. Cell. Biol., 18, 6538-6547.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 6538-6547
    • Hendrich, B.1    Bird, A.2
  • 9
    • 0033575886 scopus 로고    scopus 로고
    • The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites
    • Hendrich, B., Hardeland, U., Ng, H.H., Jiricny, J. and Bird, A. (1999) The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites. Nature, 401, 301-304.
    • (1999) Nature , vol.401 , pp. 301-304
    • Hendrich, B.1    Hardeland, U.2    Ng, H.H.3    Jiricny, J.4    Bird, A.5
  • 10
    • 0035475924 scopus 로고    scopus 로고
    • Human diseases with underlying defects in chromatin structure and modification
    • Hendrich, B. and Bickmore, W. (2001) Human diseases with underlying defects in chromatin structure and modification. Hum. Mol. Genet., 10, 2233-2242.
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 2233-2242
    • Hendrich, B.1    Bickmore, W.2
  • 11
    • 0032830639 scopus 로고    scopus 로고
    • Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2
    • Amir, R.E., Van, d. V., I, Wan, M., Tran, C.Q., Francke, U. and Zoghbi, H.Y. (1999) Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2. Nat. Genet., 23, 185-188.
    • (1999) Nat. Genet. , vol.23 , pp. 185-188
    • Amir, R.E.1    Van, D.V.I.2    Wan, M.3    Tran, C.Q.4    Francke, U.5    Zoghbi, H.Y.6
  • 14
    • 0036270792 scopus 로고    scopus 로고
    • Clinical manifestations and stages of Rett syndrome
    • Hagberg, B. (2002) Clinical manifestations and stages of Rett syndrome. Ment. Retard. Dev. Disabil. Res. Rev., 8, 61-65.
    • (2002) Ment. Retard. Dev. Disabil. Res. Rev. , vol.8 , pp. 61-65
    • Hagberg, B.1
  • 15
    • 0038182387 scopus 로고    scopus 로고
    • Rett syndrome - An update
    • Jellinger, K.A. (2003) Rett syndrome - an update. J. Neural Transm., 110, 681-701.
    • (2003) J. Neural Transm. , vol.110 , pp. 681-701
    • Jellinger, K.A.1
  • 17
    • 0037310609 scopus 로고    scopus 로고
    • The neurobiology of Rett syndrome
    • Akbarian, S. (2003) The neurobiology of Rett syndrome. Neuroscientist, 9, 57-63.
    • (2003) Neuroscientist , vol.9 , pp. 57-63
    • Akbarian, S.1
  • 18
    • 0033989812 scopus 로고    scopus 로고
    • Candidate gene analysis in Rett syndrome and the identification of 21 SNPs in Xq
    • Amir, R., Dahle, E.J., Toriolo, D. and Zoghbi, H.Y. (2000) Candidate gene analysis in Rett syndrome and the identification of 21 SNPs in Xq. Am. J. Med. Genet., 90, 69-71.
    • (2000) Am. J. Med. Genet. , vol.90 , pp. 69-71
    • Amir, R.1    Dahle, E.J.2    Toriolo, D.3    Zoghbi, H.Y.4
  • 19
    • 0023853921 scopus 로고
    • The CpG dinucleotide and human genetic disease
    • Cooper, D.N. and Youssoufian, H. (1988) The CpG dinucleotide and human genetic disease. Hum. Genet., 78, 151-155.
    • (1988) Hum. Genet. , vol.78 , pp. 151-155
    • Cooper, D.N.1    Youssoufian, H.2
  • 21
    • 0035054930 scopus 로고    scopus 로고
    • Angelman syndrome phenotype associated with mutations in MECP2, a gene encoding a methyl CpG binding protein
    • Watson, P., Black, G., Ramsden, S., Barrow, M., Super, M., Kerr, B. and Clayton-Smith, J. (2001) Angelman syndrome phenotype associated with mutations in MECP2, a gene encoding a methyl CpG binding protein. J. Med. Genet., 38, 224-228.
    • (2001) J. Med. Genet. , vol.38 , pp. 224-228
    • Watson, P.1    Black, G.2    Ramsden, S.3    Barrow, M.4    Super, M.5    Kerr, B.6    Clayton-Smith, J.7
  • 25
    • 0034711147 scopus 로고    scopus 로고
    • Two affected boys in a Rett syndrome family: Clinical and molecular findings
    • Villard, L., Kpebe, A., Cardoso, C., Chelly, P.J., Tardieu, P.M. and Fontes, M. (2000) Two affected boys in a Rett syndrome family: clinical and molecular findings. Neurology, 55, 1188-1193.
    • (2000) Neurology , vol.55 , pp. 1188-1193
    • Villard, L.1    Kpebe, A.2    Cardoso, C.3    Chelly, P.J.4    Tardieu, P.M.5    Fontes, M.6
  • 26
    • 0037271866 scopus 로고    scopus 로고
    • No correlation between phenotype and genotype in boys with a truncating MECP2 mutation
    • Ravn, K., Nielsen, J.B., Uldall, P., Hansen, F.J. and Schwartz, M. (2003) No correlation between phenotype and genotype in boys with a truncating MECP2 mutation. J. Med. Genet., 40, e5.
    • (2003) J. Med. Genet. , vol.40
    • Ravn, K.1    Nielsen, J.B.2    Uldall, P.3    Hansen, F.J.4    Schwartz, M.5
  • 28
    • 0024342686 scopus 로고
    • Identification of a mammalian protein that binds specifically to DNA containing methylated CpGs
    • Meehan, R.R., Lewis, J.D., McKay, S., Kleiner, E.L. and Bird, A.P. (1989) Identification of a mammalian protein that binds specifically to DNA containing methylated CpGs. Cell, 58, 499-507.
    • (1989) Cell , vol.58 , pp. 499-507
    • Meehan, R.R.1    Lewis, J.D.2    McKay, S.3    Kleiner, E.L.4    Bird, A.P.5
  • 29
    • 0026747761 scopus 로고
    • Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA
    • Lewis, J.D., Meehan, R.R., Henzel, W.J., Maurer-Fogy, I., Jeppesen, P., Klein, F. and Bird, A. (1992) Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA. Cell, 69, 905-914.
    • (1992) Cell , vol.69 , pp. 905-914
    • Lewis, J.D.1    Meehan, R.R.2    Henzel, W.J.3    Maurer-Fogy, I.4    Jeppesen, P.5    Klein, F.6    Bird, A.7
  • 30
    • 0029655782 scopus 로고    scopus 로고
    • DNA methylation specifies chromosomal localization of MeCP2
    • Nan, X., Tate, P., Li, E. and Bird, A. (1996) DNA methylation specifies chromosomal localization of MeCP2. Mol. Cell Biol., 16, 414-421.
    • (1996) Mol. Cell Biol. , vol.16 , pp. 414-421
    • Nan, X.1    Tate, P.2    Li, E.3    Bird, A.4
  • 31
    • 0027495467 scopus 로고
    • Dissection of the methyl-CpG binding domain from the chromosomal protein MeCP2
    • Nan, X., Meehan, R.R. and Bird, A. (1993) Dissection of the methyl-CpG binding domain from the chromosomal protein MeCP2. Nucl. Acids Res., 21, 4886-4892.
    • (1993) Nucl. Acids Res. , vol.21 , pp. 4886-4892
    • Nan, X.1    Meehan, R.R.2    Bird, A.3
  • 32
    • 0033152745 scopus 로고    scopus 로고
    • The methyl-CpG binding transcriptional repressor MeCP2 stably associates with nucleosomal DNA
    • Chandler, S.P., Guschin, D., Landsberger, N. and Wolffe, A.P. (1999) The methyl-CpG binding transcriptional repressor MeCP2 stably associates with nucleosomal DNA. Biochemistry, 38, 7008-7018.
    • (1999) Biochemistry , vol.38 , pp. 7008-7018
    • Chandler, S.P.1    Guschin, D.2    Landsberger, N.3    Wolffe, A.P.4
  • 33
    • 0035906936 scopus 로고    scopus 로고
    • Solution structure of the methyl-CpG binding domain of human MBD1 in complex with methylated DNA
    • Ohki, I., Shimotake, N., Fujita, N., Jee, J., Ikegami, T., Nakao, M. and Shirakawa, M. (2001) Solution structure of the methyl-CpG binding domain of human MBD1 in complex with methylated DNA. Cell, 105, 487-497.
    • (2001) Cell , vol.105 , pp. 487-497
    • Ohki, I.1    Shimotake, N.2    Fujita, N.3    Jee, J.4    Ikegami, T.5    Nakao, M.6    Shirakawa, M.7
  • 34
    • 0037011058 scopus 로고    scopus 로고
    • Allele-specific histone lysine methylation marks regulatory regions at imprinted mouse genes
    • Fournier, C., Goto, Y., Ballestar, E., Delaval, K., Hever, A.M., Esteller, M. and Feil, R. (2002) Allele-specific histone lysine methylation marks regulatory regions at imprinted mouse genes. EMBO J., 21, 6560-6570.
    • (2002) EMBO J. , vol.21 , pp. 6560-6570
    • Fournier, C.1    Goto, Y.2    Ballestar, E.3    Delaval, K.4    Hever, A.M.5    Esteller, M.6    Feil, R.7
  • 35
    • 0037423186 scopus 로고    scopus 로고
    • The methyl-CpG-binding protein MeCP2 links DNA methylation to histone methylation
    • Fuks, F., Hurd, P.J., Wolf, D., Nan, X., Bird, A.P. and Kouzarides, T. (2003) The methyl-CpG-binding protein MeCP2 links DNA methylation to histone methylation. J. Biol. Chem., 278, 4035-4040.
    • (2003) J. Biol. Chem. , vol.278 , pp. 4035-4040
    • Fuks, F.1    Hurd, P.J.2    Wolf, D.3    Nan, X.4    Bird, A.P.5    Kouzarides, T.6
  • 36
    • 0036889153 scopus 로고    scopus 로고
    • Inhibitors of histone deacetylase and DNA methyl-transferase synergistically activate the methylated metallothionein I promoter by activating the transcription factor MTF-1 and forming an open chromatin structure
    • Ghoshal, K., Datta, J., Majumder, S., Bai, S., Dong, X., Parthun, M. and Jacob, S.T. (2002) Inhibitors of histone deacetylase and DNA methyl-transferase synergistically activate the methylated metallothionein I promoter by activating the transcription factor MTF-1 and forming an open chromatin structure. Mol. Cell. Biol., 22, 8302-8319.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 8302-8319
    • Ghoshal, K.1    Datta, J.2    Majumder, S.3    Bai, S.4    Dong, X.5    Parthun, M.6    Jacob, S.T.7
  • 37
    • 0036848385 scopus 로고    scopus 로고
    • Heterogeneity in the modification and involvement of chromatin components of the CpG island of the silenced human CDH1 gene in cancer cells
    • Koizume, S., Tachibana, K., Sekiya, T., Hirohashi, S. and Shiraishi, M. (2002) Heterogeneity in the modification and involvement of chromatin components of the CpG island of the silenced human CDH1 gene in cancer cells. Nucl. Acids Res., 30, 4770-4780.
    • (2002) Nucl. Acids Res. , vol.30 , pp. 4770-4780
    • Koizume, S.1    Tachibana, K.2    Sekiya, T.3    Hirohashi, S.4    Shiraishi, M.5
  • 39
    • 0036182132 scopus 로고    scopus 로고
    • Precipitous release of methyl-CpG binding protein 2 and histone deacetylase 1 from the methylated human multidrug resistance gene (MDR1) on activation
    • El Osta, A., Kantharidis, P., Zalcberg, J.R. and Wolffe, A.P. (2002) Precipitous release of methyl-CpG binding protein 2 and histone deacetylase 1 from the methylated human multidrug resistance gene (MDR1) on activation. Mol. Cell. Biol., 22, 1844-1857.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 1844-1857
    • El Osta, A.1    Kantharidis, P.2    Zalcberg, J.R.3    Wolffe, A.P.4
  • 40
    • 0035890665 scopus 로고    scopus 로고
    • Altered chromatin structure associated with methylation-induced gene silencing in cancer cells: Correlation of accessibility, methylation, MeCP2 binding and acetylation
    • Nguyen, C.T., Gonzales, F.A. and Jones, P.A. (2001) Altered chromatin structure associated with methylation-induced gene silencing in cancer cells: correlation of accessibility, methylation, MeCP2 binding and acetylation. Nucl. Acids Res., 29, 4598-4606.
    • (2001) Nucl. Acids Res. , vol.29 , pp. 4598-4606
    • Nguyen, C.T.1    Gonzales, F.A.2    Jones, P.A.3
  • 41
    • 0034691236 scopus 로고    scopus 로고
    • Effects of Rett syndrome mutations of the methyl-CpG binding domain of the transcriptional repressor MeCP2 on selectivity for association with methylated DNA
    • Ballestar, E., Yusufzai, T.M. and Wolffe, A.P. (2000) Effects of Rett syndrome mutations of the methyl-CpG binding domain of the transcriptional repressor MeCP2 on selectivity for association with methylated DNA. Biochemistry, 39, 7100-7106.
    • (2000) Biochemistry , vol.39 , pp. 7100-7106
    • Ballestar, E.1    Yusufzai, T.M.2    Wolffe, A.P.3
  • 42
    • 0034327571 scopus 로고    scopus 로고
    • Functional consequences of Rett syndrome mutations on human MeCP2
    • Yusufzai, T.M. and Wolffe, A.P. (2000) Functional consequences of Rett syndrome mutations on human MeCP2. Nucl. Acids Res., 28, 4172-4179.
    • (2000) Nucl. Acids Res. , vol.28 , pp. 4172-4179
    • Yusufzai, T.M.1    Wolffe, A.P.2
  • 44
    • 0026658662 scopus 로고
    • Characterization of MeCP2, a vertebrate DNA binding protein with affinity for methylated DNA
    • Meehan, R.R., Lewis, J.D. and Bird, A.P. (1992) Characterization of MeCP2, a vertebrate DNA binding protein with affinity for methylated DNA. Nucl. Acids Res., 20, 5085-5092.
    • (1992) Nucl. Acids Res. , vol.20 , pp. 5085-5092
    • Meehan, R.R.1    Lewis, J.D.2    Bird, A.P.3
  • 45
    • 0342437491 scopus 로고    scopus 로고
    • MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin
    • Nan, X., Campoy, F.J. and Bird, A. (1997) MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin. Cell, 88, 471-481.
    • (1997) Cell , vol.88 , pp. 471-481
    • Nan, X.1    Campoy, F.J.2    Bird, A.3
  • 46
    • 0032574977 scopus 로고    scopus 로고
    • Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
    • Nan, X., Ng, H.H., Johnson, C.A., Laherty, C.D., Turner, B.M., Eisemnan, R.N. and Bird, A. (1998) Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex. Nature, 393, 386-389.
    • (1998) Nature , vol.393 , pp. 386-389
    • Nan, X.1    Ng, H.H.2    Johnson, C.A.3    Laherty, C.D.4    Turner, B.M.5    Eisemnan, R.N.6    Bird, A.7
  • 48
    • 0034192205 scopus 로고    scopus 로고
    • MeCP2 driven transcriptional repression in vitro: Selectivity for methylated DNA, action at a distance and contacts with the basal transcription machinery
    • Kaludov, N.K. and Wolffe, A.P. (2000) MeCP2 driven transcriptional repression in vitro: selectivity for methylated DNA, action at a distance and contacts with the basal transcription machinery. Nucl. Acids Res., 28, 1921-1928.
    • (2000) Nucl. Acids Res. , vol.28 , pp. 1921-1928
    • Kaludov, N.K.1    Wolffe, A.P.2
  • 49
    • 0038136913 scopus 로고    scopus 로고
    • Methyl-CpG-binding protein, MeCP2, is a target molecule for maintenance DNA methyltransferase, Dnmt1
    • Kimura, H. and Shiota, K. (2003) Methyl-CpG-binding protein, MeCP2, is a target molecule for maintenance DNA methyltransferase, Dnmt1. J. Biol. Chem., 278, 4806-4812.
    • (2003) J. Biol. Chem. , vol.278 , pp. 4806-4812
    • Kimura, H.1    Shiota, K.2
  • 51
    • 0030071685 scopus 로고    scopus 로고
    • The methyl-CpG binding protein MeCP2 is essential for embryonic development in the mouse
    • Tate, P., Skarnes, W. and Bird, A. (1996) The methyl-CpG binding protein MeCP2 is essential for embryonic development in the mouse. Nat. Genet., 12, 205-208.
    • (1996) Nat. Genet. , vol.12 , pp. 205-208
    • Tate, P.1    Skarnes, W.2    Bird, A.3
  • 52
    • 0035094767 scopus 로고    scopus 로고
    • A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome
    • Guy, J., Hendrich, B., Holmes, M., Martin, J.E. and Bird, A. (2001) A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome. Nat. Genet., 27, 322-326.
    • (2001) Nat. Genet. , vol.27 , pp. 322-326
    • Guy, J.1    Hendrich, B.2    Holmes, M.3    Martin, J.E.4    Bird, A.5
  • 53
    • 0035093830 scopus 로고    scopus 로고
    • Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice
    • Chen, R.Z., Akbarian, S., Tudor, M. and Jaenisch, R. (2001) Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice. Nat. Genet., 27, 327-331.
    • (2001) Nat. Genet. , vol.27 , pp. 327-331
    • Chen, R.Z.1    Akbarian, S.2    Tudor, M.3    Jaenisch, R.4
  • 54
    • 0028057681 scopus 로고
    • Independent regulatory elements in the nestin gene direct transgene expression to neural stem cells or muscle precursors
    • Zimmerman, L., Parr, B., Lendahl, U., Cunningham, M., McKay, R., Gavin, B., Mann, J., Vassileva, G. and McMahon, A. (1994) Independent regulatory elements in the nestin gene direct transgene expression to neural stem cells or muscle precursors. Neuron, 12, 11-24.
    • (1994) Neuron , vol.12 , pp. 11-24
    • Zimmerman, L.1    Parr, B.2    Lendahl, U.3    Cunningham, M.4    McKay, R.5    Gavin, B.6    Mann, J.7    Vassileva, G.8    McMahon, A.9
  • 57
    • 0035076360 scopus 로고    scopus 로고
    • MECP2 mutations in Danish patients with Rett syndrome: High frequency of mutations but no consistent correlations with clinical severity or with the X chromosome inactivation pattern
    • Nielsen, J.B., Henriksen, K.F., Hansen, C., Silahtaroglu, A., Schwartz, M. and Tommerup, N. (2001) MECP2 mutations in Danish patients with Rett syndrome: high frequency of mutations but no consistent correlations with clinical severity or with the X chromosome inactivation pattern. Eur. J. Hum. Genet., 9, 178-184.
    • (2001) Eur. J. Hum. Genet. , vol.9 , pp. 178-184
    • Nielsen, J.B.1    Henriksen, K.F.2    Hansen, C.3    Silahtaroglu, A.4    Schwartz, M.5    Tommerup, N.6
  • 58
    • 0033646967 scopus 로고    scopus 로고
    • Rett syndrome: Methyl-CpG-binding protein 2 mutations and phenotype-genotype correlations
    • Amir, R.E. and Zoghbi, H.Y. (2000) Rett syndrome: methyl-CpG-binding protein 2 mutations and phenotype-genotype correlations. Am. J. Med. Genet., 97, 147-152.
    • (2000) Am. J. Med. Genet. , vol.97 , pp. 147-152
    • Amir, R.E.1    Zoghbi, H.Y.2
  • 59
    • 18144443930 scopus 로고    scopus 로고
    • Long-read sequence analysis of the MECP2 gene in Rett syndrome patients: Correlation of disease severity with mutation type and location
    • Cheadle, J.P., Gill, H., Fleming, N., Maynard, J., Kerr, A., Leonard, H., Krawczak, M., Cooper, D.N., Lynch, S., Thomas, N. et al. (2000) Long-read sequence analysis of the MECP2 gene in Rett syndrome patients: correlation of disease severity with mutation type and location. Hum. Mol. Genet., 9, 1119-1129.
    • (2000) Hum. Mol. Genet. , vol.9 , pp. 1119-1129
    • Cheadle, J.P.1    Gill, H.2    Fleming, N.3    Maynard, J.4    Kerr, A.5    Leonard, H.6    Krawczak, M.7    Cooper, D.N.8    Lynch, S.9    Thomas, N.10
  • 62
    • 0037280319 scopus 로고    scopus 로고
    • Elevated methyl-CpG-binding protein 2 expression is acquired during postnatal human brain development and is correlated with alternative polyadenylation
    • Balmer, D., Goldstine, J., Rao, Y.M. and LaSalle, J.M. (2003) Elevated methyl-CpG-binding protein 2 expression is acquired during postnatal human brain development and is correlated with alternative polyadenylation. J. Mol. Med., 81, 61-68.
    • (2003) J. Mol. Med. , vol.81 , pp. 61-68
    • Balmer, D.1    Goldstine, J.2    Rao, Y.M.3    LaSalle, J.M.4
  • 63
    • 0037081840 scopus 로고    scopus 로고
    • Insight into Rett syndrome: MeCP2 levels display tissue- and cell-specific differences and correlate with neuronal maturation
    • Shahbazian, M.D., Antalffy, B., Armstrong, D.L. and Zoghbi, H.Y. (2002) Insight into Rett syndrome: MeCP2 levels display tissue- and cell-specific differences and correlate with neuronal maturation. Hum. Mol. Genet., 11, 115-124.
    • (2002) Hum. Mol. Genet. , vol.11 , pp. 115-124
    • Shahbazian, M.D.1    Antalffy, B.2    Armstrong, D.L.3    Zoghbi, H.Y.4
  • 64
    • 0037381336 scopus 로고    scopus 로고
    • The expression of methyl CpG binding factor MeCP2 correlates with cellular differentiation in the developing rat brain and in cultured cells
    • Jung, B.P., Jugloff, D.G., Zhang, G., Logan, R., Brown, S. and Eubanks, J.H. (2003) The expression of methyl CpG binding factor MeCP2 correlates with cellular differentiation in the developing rat brain and in cultured cells. J. Neurobiol., 55, 86-96.
    • (2003) J. Neurobiol. , vol.55 , pp. 86-96
    • Jung, B.P.1    Jugloff, D.G.2    Zhang, G.3    Logan, R.4    Brown, S.5    Eubanks, J.H.6
  • 66
    • 0037396585 scopus 로고    scopus 로고
    • Expression of MeCP2 in olfactory receptor neurons is developmentally regulated and occurs before synaptogenesis
    • Cohen, D.R., Matarazzo, V., Palmer, A.M., Tu, Y., Jeon, O.H., Pevsner, J. and Ronnett, G.V. (2003) Expression of MeCP2 in olfactory receptor neurons is developmentally regulated and occurs before synaptogenesis. Mol. Cell Neurosci., 22, 417-429.
    • (2003) Mol. Cell Neurosci. , vol.22 , pp. 417-429
    • Cohen, D.R.1    Matarazzo, V.2    Palmer, A.M.3    Tu, Y.4    Jeon, O.H.5    Pevsner, J.6    Ronnett, G.V.7
  • 68
    • 0034502958 scopus 로고    scopus 로고
    • Characterisation of transcriptionally active and inactive chromatin domains in neurons
    • Akhmanova, A., Verkerk, T., Langeveld, A., Grosveld, F. and Galjart, N. (2000) Characterisation of transcriptionally active and inactive chromatin domains in neurons. J. Cell Sci., 113 (Pt 24), 4463-4474.
    • (2000) J. Cell Sci. , vol.113 , Issue.PART 24 , pp. 4463-4474
    • Akhmanova, A.1    Verkerk, T.2    Langeveld, A.3    Grosveld, F.4    Galjart, N.5
  • 69
    • 0037180492 scopus 로고    scopus 로고
    • Transcriptional profiling of a mouse model for Rett syndrome reveals subtle transcriptional changes in the brain
    • Tudor, M., Akbarian, S., Chen, R.Z. and Jaenisch, R. (2002) Transcriptional profiling of a mouse model for Rett syndrome reveals subtle transcriptional changes in the brain. Proc. Natl Acad. Sci. USA, 99, 15536-15541.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 15536-15541
    • Tudor, M.1    Akbarian, S.2    Chen, R.Z.3    Jaenisch, R.4
  • 70
    • 0002963383 scopus 로고    scopus 로고
    • The ultimate chip shot: Can microarray technology deliver for neuroscience?
    • Nisenbaum, L.K. (2002) The ultimate chip shot: can microarray technology deliver for neuroscience? Genes Brain Behav., 1, 27-34.
    • (2002) Genes Brain Behav. , vol.1 , pp. 27-34
    • Nisenbaum, L.K.1
  • 71
    • 0043178993 scopus 로고    scopus 로고
    • A mutant form of MeCP2 protein associated with human Rett syndrome cannot be displaced from methylated DNA by Notch in Xenopus embryos
    • Stancheva, I., Collins, A.L., Van den Veyver, I.B., Zoghbi, H. and Meehan, R. (2003) A mutant form of MeCP2 protein associated with human Rett syndrome cannot be displaced from methylated DNA by Notch in Xenopus embryos. Mol. Cell, 12, 425-435.
    • (2003) Mol. Cell , vol.12 , pp. 425-435
    • Stancheva, I.1    Collins, A.L.2    Van den Veyver, I.B.3    Zoghbi, H.4    Meehan, R.5
  • 72
    • 0035868824 scopus 로고    scopus 로고
    • Closely related proteins MBD2 and MBD3 play distinctive but interacting roles in mouse development
    • Hendrich, B., Guy, J., Ramsahoye, B., Wilson, V.A. and Bird, A. (2001) Closely related proteins MBD2 and MBD3 play distinctive but interacting roles in mouse development. Genes Dev., 15, 710-723.
    • (2001) Genes Dev. , vol.15 , pp. 710-723
    • Hendrich, B.1    Guy, J.2    Ramsahoye, B.3    Wilson, V.A.4    Bird, A.5
  • 74
    • 0026708177 scopus 로고
    • Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
    • Li, E., Bestor, T.H. and Jaenisch, R. (1992) Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell, 69, 915-926.
    • (1992) Cell , vol.69 , pp. 915-926
    • Li, E.1    Bestor, T.H.2    Jaenisch, R.3
  • 77
    • 0037111980 scopus 로고    scopus 로고
    • Integration of long-term-memory-related synaptic plasticity involves bidirectional regulation of gene expression and chromatin structure
    • Guan, Z., Giustetto, M., Lomvardas, S., Kim, J.H., Miniaci, M.C., Schwartz, J.H., Thanos, D. and Kandel, E.R. (2002) Integration of long-term-memory-related synaptic plasticity involves bidirectional regulation of gene expression and chromatin structure. Cell, 111, 483-493.
    • (2002) Cell , vol.111 , pp. 483-493
    • Guan, Z.1    Giustetto, M.2    Lomvardas, S.3    Kim, J.H.4    Miniaci, M.C.5    Schwartz, J.H.6    Thanos, D.7    Kandel, E.R.8
  • 78
    • 0036849262 scopus 로고    scopus 로고
    • Epigenetic consequences of nucleosome dynamics
    • Ahmad, K. and Henikoff, S. (2002) Epigenetic consequences of nucleosome dynamics. Cell, 111, 281-284.
    • (2002) Cell , vol.111 , pp. 281-284
    • Ahmad, K.1    Henikoff, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.