Molecular analysis of ligand binding to the second cluster of complement-type repeats of the low density lipoprotein receptor-related protein: Evidence for an allosteric component in receptor-associated protein- mediated inhibition of ligand binding

Journal of Biological Chemistry

Volumn 272, Issue 21, 1997, Pages 13608-13613

  Horn, Ivo R ^a   Van Den Berg, Birgit M M ^a   Van Der Meijden, Petronel Z ^a   Pannekoek, Hans ^a   Van Zonneveld, Anton Jan ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

LOW DENSITY LIPOPROTEIN RECEPTOR;

ALLOSTERISM; ARTICLE; BINDING COMPETITION; DISSOCIATION CONSTANT; HUMAN; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN GLYCOSYLATION;

ANIMALS; BINDING SITES; BIOSENSING TECHNIQUES; CARRIER PROTEINS; CRICETINAE; ENZYME-LINKED IMMUNOSORBENT ASSAY; GLYCOPROTEINS; IMMUNOGLOBULIN FAB FRAGMENTS; LDL-RECEPTOR RELATED PROTEIN 1; LDL-RECEPTOR RELATED PROTEIN-ASSOCIATED PROTEIN; LIGANDS; MOLECULAR CHAPERONES; PEPTIDE FRAGMENTS; PEPTIDE MAPPING; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN BINDING; RECEPTORS, IMMUNOLOGIC; RECEPTORS, LDL; RECOMBINANT PROTEINS; TISSUE PLASMINOGEN ACTIVATOR;

CRICETINAE;

EID: 0030945761     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.21.13608     Document Type: Article

References (34)

1. Krieger, M., and Herz, J. (1994) Annu. Rev. Biochem. 63, 601-637
2. Moestrup, S. K. (1994) Biochim. Biophys. Acta 1197, 197-213
3. Strickland, D. K., Kounnas, M. Z., Williams, S. E., and Argraves, W. S. (1994) Fibrinolysis 8, 204-215
4. Orth, K., Madison, E. L., Gething, M. J., Sambrook, J. F., and Herz, J. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 7422-7426
5. Bu, G., Williams, S. E., Strickland, D. K., and Schwartz, A. L. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 7427-7431
6. Warshawsky, I., Bu, G., and Schwartz, A. L. (1993) J. Clin. Invest. 92, 937-944
7. Narita, M., Bu, G., Herz, J., and Schwartz, A. L. (1995) J. Clin. Invest. 96, 1164-1168
8. Willnow, T. E., Moehring, J. M., Inocencio, N. M., Moehring, T. J., and Herz, J. (1996) Biochem. J. 313, 71-76
9. Esser, V., Limbird, L. E., Brown, M. S., Goldstein, J. L., and Russell, D. W. (1988) J. Biol. Chem. 263, 13282-13290
10. Russell, D. W., Brown, M. S., and Goldstein, J. L. (1989) J. Biol. Chem. 264, 21682-21688
11. Moestrup, S. K., Holtet, T. L., Etzerodt, M., Thøgersen, H. C., Nykjær, A., Andreasen, P. A., Rasmussen, H. H., Sottrup-Jensen, L., and Gliemann, J. (1993) J. Biol. Chem. 268, 13691-13696
12. Willnow, T. E., Orth, K., and Herz, J. (1994) J. Biol. Chem. 269, 15827-15832
13. Horn, I. R., Moestrup, S. K., van den Berg, B. M. M., Pannekoek, H., Nielsen, M. S., and van Zonneveld, A.-J. (1995) J. Biol. Chem. 270, 11770-11775
14. Bu, G., Geuze, H. J., Strous, G. J., and Schwartz, A. L. (1995) EMBO J. 14, 2269-2280
15. Willnow, T. E., Rohlmann, A., Horton, J., Otani, H., Braun, J. R., Hammer, R. E., and Herz, J. (1996) EMBO J. 15, 2632-2639
16. Iadonato, S. P., Bu, G., Maksymovitch, E. A., and Schwartz, A. L. (1993) Biochem. J. 296, 867-875
17. Bu, G., Warshawsky, I., and Schwartz, A. L. (1994) Blood 83, 3427-3436
18. Willnow, T. E., Goldstein, J. L., Orth, K., Brown, M. S., and Herz, J. (1992) J. Biol. Chem. 267, 26172-26180
19. Warshawsky, I., Bu, G., and Schwartz, A. L. (1994) J. Biol. Chem. 269, 3325-3330
20. Bu, G., and Rennke, S. (1996) J. Biol. Chem. 271, 22218-22224
21. Sancho, E., Tonge, D. W., Hockney, R. C., and Booth, N. A. (1994) Eur. J. Biochem. 224, 125-134
22. Van Meijer, M., Roelofs, Y., Neels, J., Horrevoets, A. J. G., van Zonneveld, A.-J., and Pannekoek, H. (1996) J. Biol. Chem. 271, 7423-7428
23. Keijer, J., Linders, M., van Zonneveld, A. J., Ehrlich, H., de Boer, J. P., and Pannekoek, H. (1991) Blood 78, 401-409
24. Herz, J., Hamann, U., Rogne, S., Myklebost, O., Gausepohl, H., and Stanley, K. K. (1988) EMBO J. 7, 4119-4127
25. Ny, T., Elgh, F., and Lund, B. (1984) Proc. Natl. Acad. Sci. U.S.A. 81, 5355-5359
26. Leyte, A., Verbeet, M. P., Brodniewiecz-Proba, T., van Mourik, J. A., and Mertens, K. (1989) Biochem. J. 257, 679-683
27. Meijers, J. C. M., Mulvihill, E. R., Davie, E. W., and Chung, D. W. (1992) Biochemistry 31, 4680-4684
28. Sambrook, J., Fritsch, E. F., and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
29. Schuck, P., and Minton, A. P. (1996) Trends Biochem. Sci. 21, 458-460
30. Williams, S. E., Ashcom, J. D., Argraves, W. S., and Strickland, D. K. (1992) J. Biol. Chem. 267, 9035-9040
31. Moestrup, S. K., Birn, H., Fischer, P. B., Petersen, C. M., Verroust, P. J., Sim, R. B., Christensen, E. I., and Nexo, E. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 8612-8617
32. Saito, A., Yamazaki, H., Rader, K., Nakatani, A., Ullrich, R., Kerjaschki, D., Orlando, R. A., and Farquhar, M. G. (1996) Proc. Natl Acad. Sci. U. S. A. 93, 8601-8605
33. Orth, K., Willnow, T. E., Herz, J., Gething, M. J., and Sambrook, J. (1994) J. Biol. Chem. 269, 21117-21122
34. Nykjær, A., Kjøller, L., Cohen, R. L., Lawrence, D. A., Gliemann, J., and Andreasen, P. A. (1994) Ann. N. Y. Acad. Sci. 737, 483-485