Investigations into the stabilization of drugs by sugar glasses: III. The influence of various high-pH buffers

Pharmaceutical Research

Volumn 20, Issue 9, 2003, Pages 1437-1443

  Eriksson, Jonas H C ^a   Hinrichs, Wouter L J ^a   De Jong, Gerhardus J ^b   Somsen, Govert W ^b   Frijlink, Henderik W ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Buffers; Glass transition; Stabilization; Sugar glasses

Indexed keywords

2 (N CYCLOHEXYLAMINO)ETHANE SULFONIC ACID; 2 AMINO 2 METHYL 1,3 PROPANEDIOL; ALKALINE PHOSPHATASE; BORATE SODIUM; BUFFER; STABILIZING AGENT; SUGAR; TROMETAMOL; UNCLASSIFIED DRUG;

ARTICLE; COMPLEX FORMATION; DIFFERENTIAL SCANNING CALORIMETRY; DRUG STABILITY; ENZYME ACTIVITY; ENZYME ASSAY; FRACTIONATION; FREEZE DRYING; GLASS TRANSITION TEMPERATURE; PH; PRIORITY JOURNAL;

ALKALINE PHOSPHATASE; ANIMALS; BUFFERS; CALORIMETRY, DIFFERENTIAL SCANNING; CARBOHYDRATES; CATTLE; CRYSTALLIZATION; DRUG STABILITY; ENZYME STABILITY; FREEZE DRYING; HYDROGEN-ION CONCENTRATION; INULIN; PHARMACEUTICAL SOLUTIONS; PHASE TRANSITION; TREHALOSE;

EID: 0141678818     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1025762328267     Document Type: Article

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