Replacing succinate with glycolate buffer improves the stability of lyophilized interferon-

International Journal of Pharmaceutics

Volumn 142, Issue 1, 1996, Pages 85-95

  Lam, Xanthe M ^a   Costantino, Henry R ^a   Overcashier, David E ^a   Nguyen, Tue H ^a   Hsu, Chung C ^a  

^a GENENTECH INC   (United States)

Author keywords

Circular dichroism; Fourier transform infrared spectroscopy; Interferon ; Lyophilization; pH; Protein stability

Indexed keywords

BUFFER; GAMMA INTERFERON; GLYCOLIC ACID; SUCCINIC ACID;

ARTICLE; CIRCULAR DICHROISM; DIFFERENTIAL SCANNING CALORIMETRY; DRUG STABILITY; FREEZE DRYING; INFRARED SPECTROSCOPY; PH; PRIORITY JOURNAL; X RAY DIFFRACTION;

EID: 0030604045     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-5173(96)04656-X     Document Type: Article

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