The tissue plasminogen activator-plasminogen proteolytic cascade accelerates amyloid-β (Aβ) degradation and inhibits Aβ-induced neurodegeneration

Journal of Neuroscience

Volumn 23, Issue 26, 2003, Pages 8867-8871

  Melchor, Jerry P ^a   Pawlak, Robert ^a   Strickland, Sidney ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Alzheimer's disease; Amyloid degradation; Neurodegeneration; PAI 1; Plasmin; Protease

Indexed keywords

AMYLOID BETA PROTEIN; PLASMIN; PLASMINOGEN; PLASMINOGEN ACTIVATOR INHIBITOR 1; TISSUE PLASMINOGEN ACTIVATOR;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL DAMAGE; CONTROLLED STUDY; DISEASE ACTIVITY; DISEASE ASSOCIATION; DISEASE COURSE; MICROGLIA; MOUSE; NERVE CELL; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; UPREGULATION;

EID: 0141641077     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.23-26-08867.2003     Document Type: Article

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