Characterizing the interactions between the two subunits of the p101/p110γ/phosphoinositide 3-kinase and their role in the activation of this enzyme by G(βγ) subunits

Journal of Biological Chemistry

Volumn 274, Issue 24, 1999, Pages 17152-17158

  Krugmann, Sonja ^a   Hawkins, Phillip T ^a   Pryer, Nancy ^b   Braselmann, Sylvia ^b  

^a BABRAHAM INSTITUTE   (United Kingdom)

^b ONYX PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN SUBUNIT;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME MODIFICATION; ENZYME STRUCTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; STRUCTURE ACTIVITY RELATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; BINDING SITES; DIMERIZATION; ENZYME ACTIVATION; GTP-BINDING PROTEIN BETA SUBUNITS; GTP-BINDING PROTEIN GAMMA SUBUNITS; GTP-BINDING PROTEINS; HETEROTRIMERIC GTP-BINDING PROTEINS; HUMANS; MUTAGENESIS, SITE-DIRECTED; NEUTROPHILS; POINT MUTATION; PROTEIN BINDING; RECOMBINANT PROTEINS; SEQUENCE DELETION; SWINE;

EID: 0033546148     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.24.17152     Document Type: Article

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