-
1
-
-
0030222080
-
Induction of neuroprotective kappa B-dependent transcription by secreted forms, of the Alzheimer's beta-amyloid precursor
-
Barger S. W. and Mattson M. P. (1996) Induction of neuroprotective kappa B-dependent transcription by secreted forms, of the Alzheimer's beta-amyloid precursor. Brain Res. Mol. Brain Res. 40, 116-126.
-
(1996)
Brain Res. Mol. Brain Res.
, vol.40
, pp. 116-126
-
-
Barger, S.W.1
Mattson, M.P.2
-
2
-
-
0035816661
-
A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60
-
Cao X. and Sudhof T. C. (2001) A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60. Science 293, 115-120.
-
(2001)
Science
, vol.293
, pp. 115-120
-
-
Cao, X.1
Sudhof, T.C.2
-
3
-
-
0035871971
-
Elevated vulnerability to oxidative stress-induced cell death and activation of caspase-3 by the Swedish amyloid precursor protein mutation
-
Eckert A., Steiner B., Marques C., Leutz S., Romig H., Haass C. and Muller W. E. (2001) Elevated vulnerability to oxidative stress-induced cell death and activation of caspase-3 by the Swedish amyloid precursor protein mutation. J. Neurosci. Res. 64, 183-192.
-
(2001)
J. Neurosci. Res.
, vol.64
, pp. 183-192
-
-
Eckert, A.1
Steiner, B.2
Marques, C.3
Leutz, S.4
Romig, H.5
Haass, C.6
Muller, W.E.7
-
4
-
-
0033780610
-
A regulatory link between ER-associated protein degradation and the unfolded-protein response
-
Friedlander R., Jarosch E., Urban J., Volkwein C. and Sommer T. (2000) A regulatory link between ER-associated protein degradation and the unfolded-protein response. Nat. Cell Biol. 2, 379-384.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 379-384
-
-
Friedlander, R.1
Jarosch, E.2
Urban, J.3
Volkwein, C.4
Sommer, T.5
-
5
-
-
0029841562
-
Increased activity-regulating and neuroprotective efficacy of alpha-secretase-derived secreted amyloid precursor protein conferred by a C-terminal heparin-binding domain
-
Furukawa K., Sopher B. L., Rydel R. E., Begley J. G., Pham D. G., Martin G. M., Fox M. and Mattson M. P. (1996) Increased activity-regulating and neuroprotective efficacy of alpha-secretase-derived secreted amyloid precursor protein conferred by a C-terminal heparin-binding domain. J. Neurochem. 67, 1882-1896.
-
(1996)
J. Neurochem.
, vol.67
, pp. 1882-1896
-
-
Furukawa, K.1
Sopher, B.L.2
Rydel, R.E.3
Begley, J.G.4
Pham, D.G.5
Martin, G.M.6
Fox, M.7
Mattson, M.P.8
-
6
-
-
0032891964
-
Purification and catalytic properties of human caspase family members
-
Garcia-Calvo M., Peterson E. P., Rasper D. M., Vaillancourt J. P., Zamboni R., Nicholson D. W. and Thomberry N. A. (1999) Purification and catalytic properties of human caspase family members. Cell Death Differ. 6, 362-369.
-
(1999)
Cell Death Differ.
, vol.6
, pp. 362-369
-
-
Garcia-Calvo, M.1
Peterson, E.P.2
Rasper, D.M.3
Vaillancourt, J.P.4
Zamboni, R.5
Nicholson, D.W.6
Thomberry, N.A.7
-
7
-
-
0036877969
-
Neuronal survival in the balance: Are endoplasmic reticulum membrane proteins the fulcrum?
-
Glazner G. W. and Femyhough P. (2002) Neuronal survival in the balance: are endoplasmic reticulum membrane proteins the fulcrum? Cell Calcium 32, 421-433.
-
(2002)
Cell Calcium
, vol.32
, pp. 421-433
-
-
Glazner, G.W.1
Femyhough, P.2
-
8
-
-
0033582159
-
Endoplasmic reticulum and trans-Golgi network generate distinct populations of Alzheimer beta-amyloid peptides
-
Greenfield J. P., Tsai J., Gouras G. K., Hai B., Thinakaran G., Checler F., Sisodia S. S., Greengard P. and Xu H. (1999) Endoplasmic reticulum and trans-Golgi network generate distinct populations of Alzheimer beta-amyloid peptides. Proc. Natl Acad. Sci. USA 96, 742-747.
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 742-747
-
-
Greenfield, J.P.1
Tsai, J.2
Gouras, G.K.3
Hai, B.4
Thinakaran, G.5
Checler, F.6
Sisodia, S.S.7
Greengard, P.8
Xu, H.9
-
9
-
-
0028866435
-
The Swedish mutation causes early-onset Alzheimer's disease by beta-secretase cleavage within the secretory pathway
-
Haass C., Lemere C. A., Capell A., Citron M., Seubert P., Schenk D., Lannfelt L. and Selkoe D. J. (1995) The Swedish mutation causes early-onset Alzheimer's disease by beta-secretase cleavage within the secretory pathway. Nat. Med. 1, 1291-1296.
-
(1995)
Nat. Med.
, vol.1
, pp. 1291-1296
-
-
Haass, C.1
Lemere, C.A.2
Capell, A.3
Citron, M.4
Seubert, P.5
Schenk, D.6
Lannfelt, L.7
Selkoe, D.J.8
-
10
-
-
0033590451
-
Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase
-
Harding H. P., Zhang Y. and Ron D. (1999) Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase. Nature 397, 271-274.
-
(1999)
Nature
, vol.397
, pp. 271-274
-
-
Harding, H.P.1
Zhang, Y.2
Ron, D.3
-
12
-
-
0033258544
-
Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response
-
Katayama T., Imaizumi K., Sato N. et al. (1999) Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response. Nat. Cell Biol. 1, 479-485.
-
(1999)
Nat. Cell Biol.
, vol.1
, pp. 479-485
-
-
Katayama, T.1
Imaizumi, K.2
Sato, N.3
-
13
-
-
0141853892
-
Disturbed activation of endoplasmic reticulum stress transducers by familial Alzheimer's disease-linked presenilin 1 mutations
-
Katayama T., Imaizumi K., Honda A. et al. (2001) Disturbed activation of endoplasmic reticulum stress transducers by familial Alzheimer's disease-linked presenilin 1 mutations. J Biol. Chem 10, 10.
-
(2001)
J Biol. Chem.
, vol.10
, pp. 10
-
-
Katayama, T.1
Imaizumi, K.2
Honda, A.3
-
14
-
-
0033562966
-
Stress signaling from the lumen of the endoplasmic reticulum: Coordination of gene transcriptional and translational controls
-
Kaufman R. J. (1999) Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls. Genes Dev 13, 1211-1233.
-
(1999)
Genes Dev.
, vol.13
, pp. 1211-1233
-
-
Kaufman, R.J.1
-
15
-
-
0037047434
-
The gamma secretase-generated carboxyl-terminal domain of the amyloid precursor protein induces apoptosis via Tip60 in H4 cells
-
Kinoshita A., Whelan C. M., Berezovska O. and Hyman B. T. (2002) The gamma secretase-generated carboxyl-terminal domain of the amyloid precursor protein induces apoptosis via Tip60 in H4 cells. J. Biol. Chem. 277, 28530-28536.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 28530-28536
-
-
Kinoshita, A.1
Whelan, C.M.2
Berezovska, O.3
Hyman, B.T.4
-
16
-
-
0023852783
-
The presence of malfolded proteins in the endoplasmic reticulum signals the induction of glucose-regulated proteins
-
Kozutsumi Y., Segal M., Normington K., Gething M. J. and Sambrook J. (1988) The presence of malfolded proteins in the endoplasmic reticulum signals the induction of glucose-regulated proteins. Nature 332, 462-464.
-
(1988)
Nature
, vol.332
, pp. 462-464
-
-
Kozutsumi, Y.1
Segal, M.2
Normington, K.3
Gething, M.J.4
Sambrook, J.5
-
17
-
-
0036830947
-
Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease
-
LaFerla F. M. (2002) Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease. Nat. Rev. Neurosci. 3, 862-872.
-
(2002)
Nat. Rev. Neurosci.
, vol.3
, pp. 862-872
-
-
LaFerla, F.M.1
-
18
-
-
0037007140
-
A physiologic signaling role for the gamma-secretase-derived intracellular fragment of APP
-
Leissring M. A., Murphy M. P., Mead T. R. et al. (2002) A physiologic signaling role for the gamma-secretase-derived intracellular fragment of APP. Proc. Natl Acad. Sci. USA 99, 4697-4702.
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 4697-4702
-
-
Leissring, M.A.1
Murphy, M.P.2
Mead, T.R.3
-
19
-
-
0034698878
-
Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis
-
Nakagawa T. and Yuan J. (2000) Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis. J. Cell Biol. 150, 887-894.
-
(2000)
J. Cell Biol.
, vol.150
, pp. 887-894
-
-
Nakagawa, T.1
Yuan, J.2
-
20
-
-
0035190132
-
Endoplasmic reticulum dysfunction - A common denominator for cell injury in acute and degenerative diseases of the brain?
-
Paschen W. and Frandsen A. (2001) Endoplasmic reticulum dysfunction - a common denominator for cell injury in acute and degenerative diseases of the brain? J. Neurochem. 79, 719-725.
-
(2001)
J. Neurochem.
, vol.79
, pp. 719-725
-
-
Paschen, W.1
Frandsen, A.2
-
21
-
-
0037114971
-
Endoplasmic reticulum stress and the unfolded protein response in cellular models of Parkinson's disease
-
Ryu E. J., Harding H. P., Angelastro J. M., Vitolo O. V., Ron D. and Greene L. A. (2002) Endoplasmic reticulum stress and the unfolded protein response in cellular models of Parkinson's disease. J. Neurosci. 22, 10690-10698.
-
(2002)
J. Neurosci.
, vol.22
, pp. 10690-10698
-
-
Ryu, E.J.1
Harding, H.P.2
Angelastro, J.M.3
Vitolo, O.V.4
Ron, D.5
Greene, L.A.6
-
22
-
-
0033671650
-
Upregulation of BiP and CHOP by the unfolded-protein response is independent of presenilin expression
-
Sato N., Urano F., Yoon Leem J. et al. (2000) Upregulation of BiP and CHOP by the unfolded-protein response is independent of presenilin expression. Nat. Cell Biol. 2, 863-870.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 863-870
-
-
Sato, N.1
Urano, F.2
Yoon Leem, J.3
-
23
-
-
0035066332
-
Alzheimer's disease: Genes, proteins, and therapy
-
Selkoe D. J. (2001) Alzheimer's disease: genes, proteins, and therapy. Physiol. Rev. 81, 741-766.
-
(2001)
Physiol. Rev.
, vol.81
, pp. 741-766
-
-
Selkoe, D.J.1
-
24
-
-
0030587429
-
Brefeldin A is a potent inducer of apoptosis in human cancer cells independently of p53
-
Shao R. G., Shimizu T. and Pommier Y. (1996) Brefeldin A is a potent inducer of apoptosis in human cancer cells independently of p53. Exp. Cell Res. 227, 190-196.
-
(1996)
Exp. Cell Res.
, vol.227
, pp. 190-196
-
-
Shao, R.G.1
Shimizu, T.2
Pommier, Y.3
-
25
-
-
0035139109
-
Cellular defenses against unfolded proteins: A cell biologist thinks about neurodegenerative diseases
-
Sherman M. Y. and Goldberg A. L. (2001) Cellular defenses against unfolded proteins: a cell biologist thinks about neurodegenerative diseases. Neuron 29, 15-32.
-
(2001)
Neuron
, vol.29
, pp. 15-32
-
-
Sherman, M.Y.1
Goldberg, A.L.2
-
26
-
-
0013161392
-
Mechanisms of Ras protein targeting in mammalian cells
-
Silvius J. R. (2002) Mechanisms of Ras protein targeting in mammalian cells. J. Membr. Biol. 190, 83-92.
-
(2002)
J. Membr. Biol.
, vol.190
, pp. 83-92
-
-
Silvius, J.R.1
-
27
-
-
0033610863
-
Expression of Alzheimer's disease-associated presenilin-1 is controlled by proteolytic degradation and complex formation
-
Steiner H., Capell A., Pesold B., Citron M., Kloetzel P. M., Selkoe D. J., Romig H., Mendla K. and Haass C. (1998) Expression of Alzheimer's disease-associated presenilin-1 is controlled by proteolytic degradation and complex formation. J. Biol. Chem. 273, 32322-32331.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 32322-32331
-
-
Steiner, H.1
Capell, A.2
Pesold, B.3
Citron, M.4
Kloetzel, P.M.5
Selkoe, D.J.6
Romig, H.7
Mendla, K.8
Haass, C.9
-
28
-
-
0028322017
-
An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP.717) mutants
-
Suzuki N., Cheung T. T., Cai X. D., Odaka A., Otvos L. Jr, Eckman C., Golde T. E. and Younkin S. G. (1994) An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP.717) mutants. Science 264, 1336-1340.
-
(1994)
Science
, vol.264
, pp. 1336-1340
-
-
Suzuki, N.1
Cheung, T.T.2
Cai, X.D.3
Odaka, A.4
Otvos L., Jr.5
Eckman, C.6
Golde, T.E.7
Younkin, S.G.8
-
29
-
-
0037102939
-
Neurons overexpressing mutant presenilin-1 are more sensitive to apoptosis induced by endoplasmic reticulum-Golgi stress
-
Terro F., Czech C., Esclaire F., Elyaman W., Yardin C., Baclet M. C., Touchet N., Tremp G., Pradier L. and Hugon J. (2002) Neurons overexpressing mutant presenilin-1 are more sensitive to apoptosis induced by endoplasmic reticulum-Golgi stress. J. Neurosci. Res. 69, 530-539.
-
(2002)
J. Neurosci. Res.
, vol.69
, pp. 530-539
-
-
Terro, F.1
Czech, C.2
Esclaire, F.3
Elyaman, W.4
Yardin, C.5
Baclet, M.C.6
Touchet, N.7
Tremp, G.8
Pradier, L.9
Hugon, J.10
-
30
-
-
0032525990
-
A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Irelp) in mammalian cells
-
Tirasophon W., Welihinda A. A. and Kaufman R. J. (1998) A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Irelp) in mammalian cells. Genes Dev. 12, 1812-1824.
-
(1998)
Genes Dev.
, vol.12
, pp. 1812-1824
-
-
Tirasophon, W.1
Welihinda, A.A.2
Kaufman, R.J.3
-
31
-
-
8944259440
-
Signals from the stressed endoplasmic reticulum induce C/EBP-homologous protein (CHOP/GADD153)
-
Wang X. Z., Lawson B., Brewer J. W., Zinszner H., Sanjay A., Mi L. J., Boorstein R., Kreibich G., Hendershot L. M. and Ron D. (1996) Signals from the stressed endoplasmic reticulum induce C/EBP-homologous protein (CHOP/GADD153). Mol. Cell Biol. 16, 4273-4280.
-
(1996)
Mol. Cell Biol.
, vol.16
, pp. 4273-4280
-
-
Wang, X.Z.1
Lawson, B.2
Brewer, J.W.3
Zinszner, H.4
Sanjay, A.5
Mi, L.J.6
Boorstein, R.7
Kreibich, G.8
Hendershot, L.M.9
Ron, D.10
-
32
-
-
0036386967
-
FAD-linked presenilin-1 mutants impede translation regulation under ER stress
-
Yasuda Y., Kudo T., Katayama T. et al. (2002) FAD-linked presenilin-1 mutants impede translation regulation under ER stress. Biochem. Biophys. Res. Commun. 296, 313-318.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.296
, pp. 313-318
-
-
Yasuda, Y.1
Kudo, T.2
Katayama, T.3
-
33
-
-
0032509216
-
Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins. Involvement of basic leucine zipper transcription factors
-
Yoshida H., Haze K., Yanagi H., Yura T. and Mori K. (1998) Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins. Involvement of basic leucine zipper transcription factors. J. Biol. Chem. 273, 33741-33749.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 33741-33749
-
-
Yoshida, H.1
Haze, K.2
Yanagi, H.3
Yura, T.4
Mori, K.5
|