RNA - Ligand interactions: Affinity and specificity of aminoglycoside dimers and acridine conjugates to the HIV-1 Rev response element

Biochemistry

Volumn 42, Issue 39, 2003, Pages 11391-11403

  Luedtke, Nathan W ^a,b   Liu, Qi ^a   Tor, Yitzhak ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b YALE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; BIOSYNTHESIS; DIMERS; DNA;

BINDING ASSAYS;

RNA;

ACRIDINE DERIVATIVE; AMINOACRIDINE; AMINOGLYCOSIDE DERIVATIVE; DIMER; DNA; DOUBLE STRANDED DNA; DOUBLE STRANDED RNA; ETHIDIUM BROMIDE; FRAMYCETIN; INTERCALATING AGENT; KANAMYCIN A; LIGAND; NUCLEIC ACID; POLYADENYLIC ACID; REV PROTEIN; RNA; TOBRAMYCIN; TRANSFER RNA; VIRUS RNA;

ANISOTROPY; ARTICLE; BINDING AFFINITY; BINDING ASSAY; BINDING SITE; DNA RESPONSIVE ELEMENT; DRUG DESIGN; DRUG PROTEIN BINDING; DRUG SYNTHESIS; FLUORESCENCE; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 REV RESPONSE ELEMENT; INTERCALATION COMPLEX; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN RNA BINDING; SENSITIVITY AND SPECIFICITY;

ACRIDINES; AMINOGLYCOSIDES; ANIMALS; ANTI-BACTERIAL AGENTS; BASE SEQUENCE; BINDING SITES; BINDING, COMPETITIVE; CATTLE; DIMERIZATION; DNA; GENE PRODUCTS, REV; HIV-1; LIGANDS; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; POLY A-U; RESPONSE ELEMENTS; RNA, TRANSFER; RNA, VIRAL; SPECTROMETRY, FLUORESCENCE; SUBSTRATE SPECIFICITY;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; RNA VIRUSES;

EID: 0141483331     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi034766y     Document Type: Article

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