Fluorescence-based methods for evaluating the RNA affinity and specificity of HIV-1 Rev-RRE inhibitors

Biopolymers

Volumn 70, Issue 1, 2003, Pages 103-119

  Luedtke, Nathan W ^a   Tor, Yitzhak ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

HIV 1; Pathogens; Rev response element; RNA

Indexed keywords

BINDING ENERGY; DISEASES; DRUG PRODUCTS; FLUORESCENCE; PATHOLOGY; VIRUSES;

PATHOGENS;

RNA;

A 132; ANTIVIRUS AGENT; DB 182; DB 340; EILATIN; EILATIN DERIVATIVE; ETHIDIUM BROMIDE; FRAMYCETIN; KANAMYCIN A; KANAMYCIN B; REV PROTEIN; REV RESPONSE ELEMENT INHIBITOR; RNA; TOBRAMYCIN; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ANISOTROPY; ARTICLE; BACTERIAL INFECTION; BINDING AFFINITY; BINDING COMPETITION; BINDING SITE; CELL DIVISION; DNA RESPONSIVE ELEMENT; DRUG ACTIVITY; DRUG DESIGN; DRUG SPECIFICITY; DRUG TARGETING; EVALUATION; FLUORESCENCE; GENE EXPRESSION REGULATION; HUMAN IMMUNODEFICIENCY VIRUS 1; IC 50; INHIBITION KINETICS; LIGAND BINDING; MATHEMATICAL ANALYSIS; MOLECULAR MODEL; MOLECULAR PROBE; MOLECULAR RECOGNITION; NONHUMAN; NUCLEIC ACID ANALYSIS; NUCLEIC ACID PROBE; PATHOGENESIS; PROTEIN PROTEIN INTERACTION; REV RESPONSE ELEMENT; RNA BINDING; VIRUS INHIBITION; VIRUS REPLICATION;

AMINO ACID SEQUENCE; ANISOTROPY; ANTI-HIV AGENTS; ANTIGENS, CD4; BASE SEQUENCE; BINDING SITES; BIOPHYSICS; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHIDIUM; GENE PRODUCTS, REV; INHIBITORY CONCENTRATION 50; INTERCALATING AGENTS; KINETICS; LIGANDS; MODELS, BIOLOGICAL; MODELS, CHEMICAL; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; OPEN READING FRAMES; PEPTIDES; PHENANTHROLINES; PROTEIN BINDING; RESPONSE ELEMENTS; RNA; SEQUENCE HOMOLOGY, AMINO ACID; SEQUENCE HOMOLOGY, NUCLEIC ACID; SPECTROMETRY, FLUORESCENCE;

BACTERIA (MICROORGANISMS); HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0041836262     PISSN: 00063525     EISSN: None     Source Type: Journal    
DOI: 10.1002/bip.10428     Document Type: Article

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