Synthesis and pharmacological characterization of new silicon-based W84-type allosteric modulators for ligand binding to muscarinic M2 receptors

Journal of Organometallic Chemistry

Volumn 686, Issue 1-2, 2003, Pages 75-83

  Duda Johner, Seraina ^a   Daiß, Jürgen O ^b   Mohr, Klaus ^a   Tacke, Reinhold ^b  

^a UNIVERSITY OF BONN   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Allosteric modulators; Muscarinic receptors; Silicon; Silicon based drugs

Indexed keywords

1,6 HEXAMETHYLENEBIS[DIMETHYL(3 PHTHALIMIDOPROPYL)AMMONIUM BROMIDE]; CHOLINERGIC RECEPTOR; LIGAND; METHYLSCOPOLAMINE; MUSCARINIC M1 RECEPTOR; MUSCARINIC M2 RECEPTOR; MUSCARINIC M3 RECEPTOR; MUSCARINIC M4 RECEPTOR; MUSCARINIC M5 RECEPTOR; SILANE DERIVATIVE; SILICON DERIVATIVE;

ALLOSTERISM; ANIMAL CELL; ARTICLE; CHEMICAL REACTION; CHO CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISSOCIATION; DRUG SELECTIVITY; DRUG STRUCTURE; INHIBITION KINETICS; LIGAND BINDING; MOLECULAR CLONING; NONHUMAN; SWINE; SYNTHESIS;

SUIDAE;

EID: 0043228890     PISSN: 0022328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-328X(03)00553-9     Document Type: Article

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