SCOPUS 정보 검색 플랫폼

Life Sciences

Volumn 66, Issue 18, 2000, Pages 1675-1682

Probing the size of a hydrophobic binding pocket within the allosteric site of muscarinic acetylcholine M2-receptors

(5) Bender, Wiebke a Staudt, Markus a Tränkle, Christian b Mohr, Klaus b Holzgrabe, Ulrike c

a UNIVERSITY OF WÜRZBURG (Germany)

b UNIVERSITY OF BONN (Germany)

c NONE

Author keywords

Alkane bisammonium compounds; Allosteric modulation; M2 acetylcholine receptors; Quantitative structure activity relationships

Indexed keywords

MUSCARINIC M2 RECEPTOR; PHTHALIMIDE DERIVATIVE;

ALLOSTERISM; ARTICLE; BINDING AFFINITY; DRUG BINDING SITE; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; HYDROPHOBICITY; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REACTION ANALYSIS;

ANIMALS; HEART; MEMBRANES; MUSCARINIC ANTAGONISTS; MYOCARDIUM; QUATERNARY AMMONIUM COMPOUNDS; RECEPTOR, MUSCARINIC M2; RECEPTORS, MUSCARINIC; STRUCTURE-ACTIVITY RELATIONSHIP; SWINE;

EID: 0034708654 PISSN: 00243205 EISSN: None Source Type: Journal
DOI: 10.1016/S0024-3205(00)00490-2 Document Type: Article

Times cited : (26)

References (20)

1
- 0029126526
- S. Lazareno, N.J.M. Birdsall, Mol. Pharmacol. 48 362-378 (1995).
- (1995) Mol. Pharmacol. , vol.48 , pp. 362-378
- Lazareno, S.¹ Birdsall, N.J.M.²

2
- 0032076016
- U. Holzgrabe, K. Mohr, Drug Discovery Today, 3 214-222 (1998)
- (1998) Drug Discovery Today , vol.3 , pp. 214-222
- Holzgrabe, U.¹ Mohr, K.²

3
- 0029055030
- S. Tucek, J. Proska, Tips, 16 205-212 (1995)
- (1995) Tips , vol.16 , pp. 205-212
- Tucek, S.¹ Proska, J.²

4
- 0031009786
- J. Ellis, Drug Develop. Res. 40 193-204 (1997)
- (1997) Drug Develop. Res. , vol.40 , pp. 193-204
- Ellis, J.¹

5
- 0031955647
- A. Christopoulos, A. Lanzafame, F. Mitchelson, Clin. Exp. Pharmacol. Phys. 25 185-194 (1998)
- (1998) Clin. Exp. Pharmacol. Phys. , vol.25 , pp. 185-194
- Christopoulos, A.¹ Lanzafame, A.² Mitchelson, F.³

6
- 0030433044
- C. Tränkle, E. Kostenis, U. Burgmer, K. Mohr, J. Pharmacol. Exp. Ther., 279 926-933 (1996)
- (1996) J. Pharmacol. Exp. Ther. , vol.279 , pp. 926-933
- Tränkle, C.¹ Kostenis, E.² Burgmer, U.³ Mohr, K.⁴

7
- 0028231689
- J. Proska, S. Tucek, Mol. Pharmacol., 45 709-717 (1998)
- (1998) Mol. Pharmacol. , vol.45 , pp. 709-717
- Proska, J.¹ Tucek, S.²

8
- 0013686486
- 787.808
- M. Waelbroeck, P. Robberecht, P. De-Neef, J. Christophe, J. Recept. Res., 8 787.808 (1988)
- (1988) J. Recept. Res. , vol.8
- Waelbroeck, M.¹ Robberecht, P.² De-Neef, P.³ Christophe, J.⁴

9
- 0002597710
- G. Bejeuhr, U. Holzgrabe, K. Mohr, U. Sürig, A. v. Petersenn, Pharm. Pharmacol. Lett., 2 100-103 (1992)
- (1992) Pharm. Pharmacol. Lett. , vol.2 , pp. 100-103
- Bejeuhr, G.¹ Holzgrabe, U.² Mohr, K.³ Sürig, U.⁴ Petersenn, A.V.⁵

10
- 0000246198
- E. Kostenis, H.M. Botero Cid, U. Holzgrabe, K. Mohr, Eur. J. Pharmacol., 314 385-392 (1996)
- (1996) Eur. J. Pharmacol. , vol.314 , pp. 385-392
- Kostenis, E.¹ Botero Cid, H.M.² Holzgrabe, U.³ Mohr, K.⁴

11
- 0028256010
- G. Bejeuhr, G. Blaschke, U. Holzgrabe, K. Mohr, U. Sürig, G. Terfloth, J. Pharm. Pharmacol., 46 108-112 (1994)
- (1994) J. Pharm. Pharmacol. , vol.46 , pp. 108-112
- Bejeuhr, G.¹ Blaschke, G.² Holzgrabe, U.³ Mohr, K.⁴ Sürig, U.⁵ Terfloth, G.⁶

12
- 0031595749
- C. Tränkle, E. Mies-Klomfass, M.H. Botero Cid, U. Holzgrabe, K. Mohr, Mol. Pharmacol., 54 139-145 (1998)
- (1998) Mol. Pharmacol. , vol.54 , pp. 139-145
- Tränkle, C.¹ Mies-Klomfass, E.² Botero Cid, M.H.³ Holzgrabe, U.⁴ Mohr, K.⁵

13
- 0030207040
- U. Holzgrabe, M. Wagener, J. Gasteiger, J. Mol. Graphics, 14 185-193 (1996)
- (1996) J. Mol. Graphics , vol.14 , pp. 185-193
- Holzgrabe, U.¹ Wagener, M.² Gasteiger, J.³

14
- 0030240344
- U. Holzgrabe, A.J. Hopfinger, J. Chem. Inf. Comput. Sci. 36 1018-1024 (1996)
- (1996) J. Chem. Inf. Comput. Sci. , vol.36 , pp. 1018-1024
- Holzgrabe, U.¹ Hopfinger, A.J.²

15
- 0344507513
- T. Nassif-Makki, C. Tränkle, D. Zlotos, G. Bejeuhr, A. Cambareri, C. Pfletschinger, E. Kostenis, K. Mohr, U. Holzgrabe; J. Med. Chem. 42 849-858 (1999)
- (1999) J. Med. Chem. , vol.42 , pp. 849-858
- Nassif-Makki, T.¹ Tränkle, C.² Zlotos, D.³ Bejeuhr, G.⁴ Cambareri, A.⁵ Pfletschinger, C.⁶ Kostenis, E.⁷ Mohr, K.⁸ Holzgrabe, U.⁹

16
- 0038342826
- M. Staudt, C. Tränkle, K. Mohr, U. Holzgrabe, Life Sci. 62 423-429 (1998)
- (1998) Life Sci. , vol.62 , pp. 423-429
- Staudt, M.¹ Tränkle, C.² Mohr, K.³ Holzgrabe, U.⁴

17
- 0028334668
- H. M. Botero Cid, U. Holzgrabe, E. Kostenis, K. Mohr, and C. Tränkle, J. Med. Chem., 37 1439-1445 (1994).
- (1994) J. Med. Chem. , vol.37 , pp. 1439-1445
- Botero Cid, H.M.¹ Holzgrabe, U.² Kostenis, E.³ Mohr, K.⁴ Tränkle, C.⁵

18
- 0028603576
- E. Kostenis, U. Holzgrabe and K. Mohr, Eur. J. Med. Chem., 29 947-953 (1994).
- (1994) Eur. J. Med. Chem. , vol.29 , pp. 947-953
- Kostenis, E.¹ Holzgrabe, U.² Mohr, K.³

19
- 0013686420
- Ludwigshafen, Germany
- H. Kubinyi, BASF AG, 67056 Ludwigshafen, Germany, 1997.
- (1997) BASF AG, 67056
- Kubinyi, H.¹

20
- 0003896535
- VCH, Weinheim
- H. Kubinyi, QSAR: Mansch Analysis and Related Approaches; VCH, Weinheim, 1993
- (1993) QSAR: Mansch Analysis and Related Approaches
- Kubinyi, H.¹

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.