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Volumn 33, Issue 8, 2003, Pages 2186-2196

Vav exchange factor counteracts the HIV-1 Nef-mediated decrease of plasma membrane GM1 and NF-AT activity in T cells

Author keywords

GM1; Nef; NF AT; Vav

Indexed keywords

CALCINEURIN; CALCIUM ION; GANGLIOSIDE GM1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; JANUS KINASE; NEF PROTEIN; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR NFAT; VAV PROTEIN;

EID: 0042977420     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200323682     Document Type: Article
Times cited : (9)

References (56)
  • 2
    • 0032101348 scopus 로고    scopus 로고
    • Membrane compartmentation is required for efficient T cell activation
    • Xavier, R., Brennan, T., Li, Q., McCormack, C. and Seed, B., Membrane compartmentation is required for efficient T cell activation. Immunity 1998. 8: 723-732.
    • (1998) Immunity , vol.8 , pp. 723-732
    • Xavier, R.1    Brennan, T.2    Li, Q.3    McCormack, C.4    Seed, B.5
  • 4
    • 0032142953 scopus 로고    scopus 로고
    • LAT palmitoylation: Its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation
    • Zhang, W., Trible, R. P. and Samelson, L. E., LAT palmitoylation: its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation. Immunity 1998. 9: 239-246.
    • (1998) Immunity , vol.9 , pp. 239-246
    • Zhang, W.1    Trible, R.P.2    Samelson, L.E.3
  • 5
    • 0026662674 scopus 로고
    • The nature of large noncovalent complexes containing glycosyl-phosphatidylinositol-achored membrane glycoproteins and protein tyrosine kinases
    • Cinak, T. and Horejsi, V., The nature of large noncovalent complexes containing glycosyl-phosphatidylinositol-achored membrane glycoproteins and protein tyrosine kinases. J. Immunol. 1992. 149: 2262-2270.
    • (1992) J. Immunol. , vol.149 , pp. 2262-2270
    • Cinak, T.1    Horejsi, V.2
  • 6
    • 0033033321 scopus 로고    scopus 로고
    • Clusters of glycolipid and glycosylphosphatidylinositol-anchored proteins in lymphoid cells: Accumulation of actin regulated by local tyrosine phosphorylation
    • Harder, T. and Simons, K., Clusters of glycolipid and glycosylphosphatidylinositol-anchored proteins in lymphoid cells: accumulation of actin regulated by local tyrosine phosphorylation. Eur. J. Immunol. 1999. 29: 556-562.
    • (1999) Eur. J. Immunol. , vol.29 , pp. 556-562
    • Harder, T.1    Simons, K.2
  • 7
    • 0032727709 scopus 로고    scopus 로고
    • Aggregation of lipid rafts accompaines signaling via the T cell antigen receptor
    • Janes, P. W., Steven, C. L. and Magee, A. I., Aggregation of lipid rafts accompaines signaling via the T cell antigen receptor. J. Cell Biol. 1999. 147: 447-461.
    • (1999) J. Cell Biol. , vol.147 , pp. 447-461
    • Janes, P.W.1    Steven, C.L.2    Magee, A.I.3
  • 9
    • 0031874024 scopus 로고    scopus 로고
    • CD28 affects the earliest signaling events generated by TCR engagement
    • Tuosto, L. and Acuto, O., CD28 affects the earliest signaling events generated by TCR engagement. Eur. J. Immunol. 1998. 28: 2131-2142.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 2131-2142
    • Tuosto, L.1    Acuto, O.2
  • 10
    • 0033613826 scopus 로고    scopus 로고
    • T lymphocyte costimulation mediated by reorganization of membrane microdomains
    • Viola, A., Schroeder, S., Sakakibara, Y. and Lanzavecchia, A., T lymphocyte costimulation mediated by reorganization of membrane microdomains. Science 1999. 283: 680-682.
    • (1999) Science , vol.283 , pp. 680-682
    • Viola, A.1    Schroeder, S.2    Sakakibara, Y.3    Lanzavecchia, A.4
  • 11
    • 0035803552 scopus 로고    scopus 로고
    • Cytotoxic T lymhpocyte antigen 4 and CD28 modulate cell surface raft expression in their regulation of T cell function
    • Martin, M., Scheider, H., Azouz, A. and Rudd, C. E., Cytotoxic T lymhpocyte antigen 4 and CD28 modulate cell surface raft expression in their regulation of T cell function. J. Exp. Med. 2001. 194: 1675-1681.
    • (2001) J. Exp. Med. , vol.194 , pp. 1675-1681
    • Martin, M.1    Scheider, H.2    Azouz, A.3    Rudd, C.E.4
  • 13
    • 0034834457 scopus 로고    scopus 로고
    • Lipid rafts and HIV pathogenesis: Host membrane cholesterol is required for infection by HIV type 1
    • Liao, Z., Cimakasky, L. M., Hampton, R., Nguyen, D. H. and Hildreth, J. E., Lipid rafts and HIV pathogenesis: host membrane cholesterol is required for infection by HIV type 1. AIDS Res. Hum. Retroviruses 2001. 17: 1009-1019.
    • (2001) AIDS Res. Hum. Retroviruses , vol.17 , pp. 1009-1019
    • Liao, Z.1    Cimakasky, L.M.2    Hampton, R.3    Nguyen, D.H.4    Hildreth, J.E.5
  • 14
    • 0034015604 scopus 로고    scopus 로고
    • Evidence for budding of human immunodeficiency virus type 1 selectively from glycolipid-enriched membrane lipid rafts
    • Nguyen, D. H. and Hildreth, J. E. K., Evidence for budding of human immunodeficiency virus type 1 selectively from glycolipid-enriched membrane lipid rafts. J. Virol. 2000. 74: 3264-3272.
    • (2000) J. Virol. , vol.74 , pp. 3264-3272
    • Nguyen, D.H.1    Hildreth, J.E.K.2
  • 15
    • 0025281329 scopus 로고
    • Structure and expression of tat-, rev-, and nef-specific transcripts of human immunodeficiency virus type 1 in infected lymphocytes and macrophages
    • Robert-Guroff, M., Popovic, M., Gartner, S., Markham, P., Gallo, R. C. and Reitz, M. S., Structure and expression of tat-, rev-, and nef-specific transcripts of human immunodeficiency virus type 1 in infected lymphocytes and macrophages. J. Virol. 1990. 64: 3391-3398.
    • (1990) J. Virol. , vol.64 , pp. 3391-3398
    • Robert-Guroff, M.1    Popovic, M.2    Gartner, S.3    Markham, P.4    Gallo, R.C.5    Reitz, M.S.6
  • 16
    • 0034602776 scopus 로고    scopus 로고
    • The Nef protein of HIV-1 associates with rafts and primes T cells for activation
    • Wang, J. K., Kiyokawa, E., Verdin, E. and Trono, D., The Nef protein of HIV-1 associates with rafts and primes T cells for activation. Proc. Natl. Acad. Sci. USA 2000. 97: 394-399.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 394-399
    • Wang, J.K.1    Kiyokawa, E.2    Verdin, E.3    Trono, D.4
  • 18
    • 0031774858 scopus 로고    scopus 로고
    • Zeta chain of the T cell receptor interacts with nef of simian immunodeficiency virus and human immunodeficiency virus type 2
    • Howe, A. Y., Jung, J. U. and Desrosiers, R. C., Zeta chain of the T cell receptor interacts with nef of simian immunodeficiency virus and human immunodeficiency virus type 2. J. Virol. 1998. 72: 9827-9834.
    • (1998) J. Virol. , vol.72 , pp. 9827-9834
    • Howe, A.Y.1    Jung, J.U.2    Desrosiers, R.C.3
  • 19
    • 0029962938 scopus 로고    scopus 로고
    • Physical and functional interaction of Nef with Lck. HIV-1 Nef-induced T cell signaling defects
    • Collette, Y., Dutartre, H., Benziane, A., Ramos, M., Benarous, R., Harris, M. and Olive, D., Physical and functional interaction of Nef with Lck. HIV-1 Nef-induced T cell signaling defects. J. Biol. Chem. 1996. 271: 6333-6341.
    • (1996) J. Biol. Chem. , vol.271 , pp. 6333-6341
    • Collette, Y.1    Dutartre, H.2    Benziane, A.3    Ramos, M.4    Benarous, R.5    Harris, M.6    Olive, D.7
  • 20
    • 0034134113 scopus 로고    scopus 로고
    • Interactions of HIV-1 Nef with cellular signal transducing proteins
    • Renkema, G. H. and Saksela, K., Interactions of HIV-1 Nef with cellular signal transducing proteins. Front. Biosci. 2000. 5: 268-283.
    • (2000) Front. Biosci. , vol.5 , pp. 268-283
    • Renkema, G.H.1    Saksela, K.2
  • 21
    • 0026591451 scopus 로고
    • The hematopoietically expressed vav proto-oncogene shares homology with the dbl GDP-GTP exchange factor, the bcr gene and a yeast gene (CDC24) involved in cytoskeletal organization
    • Adams, J. M., Houston, H., Allen, J., Lints, T. and Harvey, R., The hematopoietically expressed vav proto-oncogene shares homology with the dbl GDP-GTP exchange factor, the bcr gene and a yeast gene (CDC24) involved in cytoskeletal organization. Oncogene 1992. 7: 611-618.
    • (1992) Oncogene , vol.7 , pp. 611-618
    • Adams, J.M.1    Houston, H.2    Allen, J.3    Lints, T.4    Harvey, R.5
  • 22
    • 0026633378 scopus 로고
    • Tyrosine phosphorilation of the vav proto-oncogene product in activated B cells
    • Bustelo, X. R. and Barbacid, M., Tyrosine phosphorilation of the vav proto-oncogene product in activated B cells. Science 1992. 256: 1196-1199.
    • (1992) Science , vol.256 , pp. 1196-1199
    • Bustelo, X.R.1    Barbacid, M.2
  • 23
    • 0033153464 scopus 로고    scopus 로고
    • Activation of Vav by Nef induces cytoskeletal rearrangements and downstream effector functions
    • Fackler, O. T., Luo, W., Geyer, M., Alberts, A. S. and Peterlin, B. M., Activation of Vav by Nef induces cytoskeletal rearrangements and downstream effector functions. Mol. Cells 1999. 3: 729-739.
    • (1999) Mol. Cells , vol.3 , pp. 729-739
    • Fackler, O.T.1    Luo, W.2    Geyer, M.3    Alberts, A.S.4    Peterlin, B.M.5
  • 24
    • 0343494918 scopus 로고    scopus 로고
    • Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain
    • Lee, C. H., Saksela, K., Mirza, U. A., Chait, B. T. and Kuriyan, J., Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain. Cell 1996. 85: 931-942.
    • (1996) Cell , vol.85 , pp. 931-942
    • Lee, C.H.1    Saksela, K.2    Mirza, U.A.3    Chait, B.T.4    Kuriyan, J.5
  • 25
    • 0036230879 scopus 로고    scopus 로고
    • Live and let die: Nef functions beyond HIV replication
    • Fackler, O. T. and Baur, A. S., Live and let die: Nef functions beyond HIV replication. Immunity 2002. 16: 493-497.
    • (2002) Immunity , vol.16 , pp. 493-497
    • Fackler, O.T.1    Baur, A.S.2
  • 26
    • 0028355604 scopus 로고
    • Human immunodeficiency virus type 1 Nef protein down-regulates transcription factors NF-kappa B and AP-1 in human T cells in vitro after T cell receptor stimulation
    • Bandres, J. C. and Ratner, L., Human immunodeficiency virus type 1 Nef protein down-regulates transcription factors NF-kappa B and AP-1 in human T cells in vitro after T cell receptor stimulation. J. Virol. 1994. 68: 3243-3249.
    • (1994) J. Virol. , vol.68 , pp. 3243-3249
    • Bandres, J.C.1    Ratner, L.2
  • 27
    • 0031039979 scopus 로고    scopus 로고
    • Separable functions of Nef disrupt two aspects of T cell receptor machinery: CD4 expression and CD3 signaling
    • Iafrate, A. J., Bronson, S. and Skowronski, J., Separable functions of Nef disrupt two aspects of T cell receptor machinery: CD4 expression and CD3 signaling. EMBO J. 1997. 16: 673-684.
    • (1997) EMBO J. , vol.16 , pp. 673-684
    • Iafrate, A.J.1    Bronson, S.2    Skowronski, J.3
  • 28
    • 0030978195 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 Nef does not alter T cell sensitivity to antigen-specific stimulation
    • Page, K. A., van Schooten, W. C. and Feinberg, M. B., Human immunodeficiency virus type 1 Nef does not alter T cell sensitivity to antigen-specific stimulation. J. Virol. 1997. 71: 3776-3787.
    • (1997) J. Virol. , vol.71 , pp. 3776-3787
    • Page, K.A.1    van Schooten, W.C.2    Feinberg, M.B.3
  • 29
    • 0035041196 scopus 로고    scopus 로고
    • Changes in the T cell receptor macromolecular signaling complex and membrane microdomains during T cell development and activation
    • Leitenberg, D., Balamuth, F. and Bottomly, K., Changes in the T cell receptor macromolecular signaling complex and membrane microdomains during T cell development and activation. Semin. Immunol. 2001. 13: 129-138.
    • (2001) Semin. Immunol. , vol.13 , pp. 129-138
    • Leitenberg, D.1    Balamuth, F.2    Bottomly, K.3
  • 31
    • 0032525137 scopus 로고    scopus 로고
    • The SH3 domain-binding surface and an acidic motif in HIV-1 Nef regulate trafficking of class I MHC complexes
    • Greenberg, M. E., Iafrate, A. J. and Skowronski, J., The SH3 domain-binding surface and an acidic motif in HIV-1 Nef regulate trafficking of class I MHC complexes. EMBO J. 1998. 17: 2777-2789.
    • (1998) EMBO J. , vol.17 , pp. 2777-2789
    • Greenberg, M.E.1    Iafrate, A.J.2    Skowronski, J.3
  • 32
    • 0032076086 scopus 로고    scopus 로고
    • Interactions between HIV-1 Nef and vacuolar ATPase facilitate the internalization of CD4
    • Lu, X., Yu, H., Liu, S. H., Brodsky, F. M. and Peterlin, B. M., Interactions between HIV-1 Nef and vacuolar ATPase facilitate the internalization of CD4. Immunity 1998. 8: 647-656.
    • (1998) Immunity , vol.8 , pp. 647-656
    • Lu, X.1    Yu, H.2    Liu, S.H.3    Brodsky, F.M.4    Peterlin, B.M.5
  • 33
    • 0033776709 scopus 로고    scopus 로고
    • HIV-1 Nef protein binds to the cellular protein PACS-1 to down-regulate class I major histocompatibility complexes
    • Piguet, V., Wan, L., Borel, C., Mangasarian, A., Demaurex, N., Thomas, G. and Trono, D., HIV-1 Nef protein binds to the cellular protein PACS-1 to down-regulate class I major histocompatibility complexes. Nat. Cell. Biol. 2000. 2: 163-167.
    • (2000) Nat. Cell. Biol. , vol.2 , pp. 163-167
    • Piguet, V.1    Wan, L.2    Borel, C.3    Mangasarian, A.4    Demaurex, N.5    Thomas, G.6    Trono, D.7
  • 34
    • 0029041568 scopus 로고
    • Transcriptional regulation of the IL-2 gene
    • Jain, J., Loh, C. and Rao, A., Transcriptional regulation of the IL-2 gene. Curr. Opin. Immunol. 1995. 7: 333-342.
    • (1995) Curr. Opin. Immunol. , vol.7 , pp. 333-342
    • Jain, J.1    Loh, C.2    Rao, A.3
  • 35
    • 0031033292 scopus 로고    scopus 로고
    • Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product
    • Crespo, P., Schuebel, K. E., Ostrom, A. A., Gutkind, J. S. and Bustelo, X. R., Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product. Nature 1997. 385: 169-172.
    • (1997) Nature , vol.385 , pp. 169-172
    • Crespo, P.1    Schuebel, K.E.2    Ostrom, A.A.3    Gutkind, J.S.4    Bustelo, X.R.5
  • 37
    • 0032188987 scopus 로고    scopus 로고
    • A Nck-PAK1 signaling module is required for T cell receptor-mediated activation of NF-AT, but not of JNK
    • Yablonski, D., Lawrence, P. K., Qiang, D. and Weiss, A., A Nck-PAK1 signaling module is required for T cell receptor-mediated activation of NF-AT, but not of JNK. EMBO J. 1998. 17: 5647-5657.
    • (1998) EMBO J. , vol.17 , pp. 5647-5657
    • Yablonski, D.1    Lawrence, P.K.2    Qiang, D.3    Weiss, A.4
  • 38
    • 0035851918 scopus 로고    scopus 로고
    • Vav1/Rac-dependent actin cytoskeleton reorganization is required for lipid raft clustering in T cells
    • Villalba, M., Bi, K., Rodriguez, F., Tanaka, Y., Schoenberger, S. and Altman, A., Vav1/Rac-dependent actin cytoskeleton reorganization is required for lipid raft clustering in T cells. J. Cell Biol. 2001. 155: 331-338.
    • (2001) J. Cell Biol. , vol.155 , pp. 331-338
    • Villalba, M.1    Bi, K.2    Rodriguez, F.3    Tanaka, Y.4    Schoenberger, S.5    Altman, A.6
  • 40
    • 0033518291 scopus 로고    scopus 로고
    • Identification of the Nef-associated kinase as p21-activated kinase 2
    • Renkema, G. H., Manninen, A., Mann, D. A., Harris, M. and Saksela, K., Identification of the Nef-associated kinase as p21-activated kinase 2. Curr. Biol. 1999. 9: 1407-1410.
    • (1999) Curr. Biol. , vol.9 , pp. 1407-1410
    • Renkema, G.H.1    Manninen, A.2    Mann, D.A.3    Harris, M.4    Saksela, K.5
  • 41
    • 0030475891 scopus 로고    scopus 로고
    • CDC42 and Rac1 are implicated in the activation of the Nef-associated kinase and replication of HIV-1
    • Lu, X., Wu, X., Plemenitas, A., Yu, H., Sawai, E. T., Abo, A. and Peterlin, B. M., CDC42 and Rac1 are implicated in the activation of the Nef-associated kinase and replication of HIV-1. Curr. Biol. 1996. 6: 1677-1684.
    • (1996) Curr. Biol. , vol.6 , pp. 1677-1684
    • Lu, X.1    Wu, X.2    Plemenitas, A.3    Yu, H.4    Sawai, E.T.5    Abo, A.6    Peterlin, B.M.7
  • 42
    • 0034292369 scopus 로고    scopus 로고
    • CD28 utilizes Vav-1 to enhance TCR-proximal signaling and NF-AT activation
    • Michel, F., Mangino, G., Attal-Bonnefoy, G., Tuosto, L., Olive, D. and Acuto, O., CD28 utilizes Vav-1 to enhance TCR-proximal signaling and NF-AT activation. J. Immunol. 2000. 165: 3820-3829.
    • (2000) J. Immunol. , vol.165 , pp. 3820-3829
    • Michel, F.1    Mangino, G.2    Attal-Bonnefoy, G.3    Tuosto, L.4    Olive, D.5    Acuto, O.6
  • 43
    • 0035368515 scopus 로고    scopus 로고
    • Dynamic Nef and Nef dynamics: How structure could explain the complex activities of this small HIV protein
    • Arold, S. T. and Baur, A. S., Dynamic Nef and Nef dynamics: how structure could explain the complex activities of this small HIV protein Trends Biochem. Sci. 2001. 26: 356-363.
    • (2001) Trends Biochem. Sci. , vol.26 , pp. 356-363
    • Arold, S.T.1    Baur, A.S.2
  • 44
    • 0028062729 scopus 로고
    • Physical interaction of the HIV-1 Nef protein with beta-COP, a component of non-clathrin-coated vesicles essential for membrane traffic
    • Benichou, S., Bomsel, M., Bodeus, M., Durand, H., Doute, M., Letourneur, F., Camonis, J. and Benarous, R., Physical interaction of the HIV-1 Nef protein with beta-COP, a component of non-clathrin-coated vesicles essential for membrane traffic. J. Biol. Chem. 1994. 269: 30073-30076.
    • (1994) J. Biol. Chem. , vol.269 , pp. 30073-30076
    • Benichou, S.1    Bomsel, M.2    Bodeus, M.3    Durand, H.4    Doute, M.5    Letourneur, F.6    Camonis, J.7    Benarous, R.8
  • 45
    • 0035844009 scopus 로고    scopus 로고
    • Domain assembly, surface accessibility and sequence conservation in full length HIV-1 Nef
    • Geyer, M. and Peterlin, B. M., Domain assembly, surface accessibility and sequence conservation in full length HIV-1 Nef. FEBS Lett. 2001. 496: 91-95.
    • (2001) FEBS Lett. , vol.496 , pp. 91-95
    • Geyer, M.1    Peterlin, B.M.2
  • 46
    • 0032566903 scopus 로고    scopus 로고
    • SH3-Domain binding function of HIV-1 Nef is required for association with a PAK-related kinase
    • Manninen, A., Hiipakka, M., Vihinen, M., Lu, W., Mayer, B. J. and Saksela, K., SH3-Domain binding function of HIV-1 Nef is required for association with a PAK-related kinase. Virology 1998. 250: 273-282.
    • (1998) Virology , vol.250 , pp. 273-282
    • Manninen, A.1    Hiipakka, M.2    Vihinen, M.3    Lu, W.4    Mayer, B.J.5    Saksela, K.6
  • 47
    • 0028290825 scopus 로고
    • Control of RNA initiation and elongation at the HIV-1 promoter
    • Jones, K. A. and Peterlin, B. M., Control of RNA initiation and elongation at the HIV-1 promoter. Annu. Rev. Biochem. 1994. 63: 717-743.
    • (1994) Annu. Rev. Biochem. , vol.63 , pp. 717-743
    • Jones, K.A.1    Peterlin, B.M.2
  • 48
    • 0037155156 scopus 로고    scopus 로고
    • HIV Nef increases T cell ERK MAP kinase activity
    • Schrager, J. A., Der Minassian, V. and Marsh, J. W., HIV Nef increases T cell ERK MAP kinase activity. J. Biol. Chem. 2002. 277: 6137-6142.
    • (2002) J. Biol. Chem. , vol.277 , pp. 6137-6142
    • Schrager, J.A.1    Der Minassian, V.2    Marsh, J.W.3
  • 51
    • 0034948709 scopus 로고    scopus 로고
    • Nef triggers a transcriptional program in T cells imitating single-signal T cell activation and inducing HIV virulence meditors
    • Simmons, A., Aluvihare, V. and McMichael, A., Nef triggers a transcriptional program in T cells imitating single-signal T cell activation and inducing HIV virulence meditors. Immunity 2001. 14: 763-777.
    • (2001) Immunity , vol.14 , pp. 763-777
    • Simmons, A.1    Aluvihare, V.2    McMichael, A.3
  • 52
    • 0037097772 scopus 로고    scopus 로고
    • CD4-Lck through TCR and in the absence of Vav exchange factor induces Bax increase and mitochondrial damage
    • Tuosto, L., Marinari, B. and Piccolella, E., CD4-Lck through TCR and in the absence of Vav exchange factor induces Bax increase and mitochondrial damage. J. Immunol. 2002. 168: 6106-6112.
    • (2002) J. Immunol. , vol.168 , pp. 6106-6112
    • Tuosto, L.1    Marinari, B.2    Piccolella, E.3
  • 53
    • 0028485232 scopus 로고
    • HIV-1 Nef leads to inhibition or activation of T cells depending on its intracellular localization
    • Baur, A. S., Sawai, E. T., Dazin, P., Fanti, W. E., Cheng-Mayer, C. and Peterlin, B. M., HIV-1 Nef leads to inhibition or activation of T cells depending on its intracellular localization. Immunity 1994. 1: 373-384.
    • (1994) Immunity , vol.1 , pp. 373-384
    • Baur, A.S.1    Sawai, E.T.2    Dazin, P.3    Fanti, W.E.4    Cheng-Mayer, C.5    Peterlin, B.M.6
  • 54
    • 0030684068 scopus 로고    scopus 로고
    • Co-localization of HIV-1 Nef with the adaptor protein complex correlates with Nef-induced CD4 down-regulation
    • Greenberg, M. E., Bronson, S., Lock, M., Neumann, M., Pavlakis, G. N. and Skowronski, J., Co-localization of HIV-1 Nef with the adaptor protein complex correlates with Nef-induced CD4 down-regulation. EMBO J. 1997. 16: 6964-6976.
    • (1997) EMBO J. , vol.16 , pp. 6964-6976
    • Greenberg, M.E.1    Bronson, S.2    Lock, M.3    Neumann, M.4    Pavlakis, G.N.5    Skowronski, J.6


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