Nef increases infectivity of HIV via lipid rafts

Current Biology

Volumn 11, Issue 11, 2001, Pages 875-879

  Zheng, Yong Hui ^a   Plemenitas, Ana ^b   Linnemann, Thomas ^a   Fackler, Oliver T ^a   Peterlin, B Matija ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF LJUBLJANA   (Slovenia)

Author keywords

[No Author keywords available]

Indexed keywords

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0035811040     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(01)00237-8     Document Type: Article

References (26)

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4. Evidence for budding of human immunodeficiency virus type I selectively from glycolipid-enriched membrane lipid rafts
5. HIV-1 auxiliary proteins: Making connections in a dying cell
6. Interactions of HIV-1 NEF with cellular signal transducing proteins
7. Structure and expression of tat-, rev-, and nef-specific transcripts of human immunodeficiency virus type 1 in infected lymphocytes and macrophages
8. The Nef protein of HIV-1 associates with rafts and primes T cells for activation
9. Membrane compartmentation is required for efficient T cell activation
10. A detergent-free method for purifying caveolae membrane from tissue culture cells
11. Exclusion of CD45 inhibits activity of p56lck associated with glycolipid-enriched membrane domains
12. Localization of human immunodeficiency virus type 1 Gag and Env at the plasma membrane by confocal imaging
13. Detection of replication-competent and pseudotyped human immunodeficiency virus with a sensitive cell line on the basis of activation of an integrated β-galactosidase gene
14. Intracellular cholesterol transport
15. Regulation of lipid metabolism in in vitro cultured minimal deviation Hepatoma 7288C
16. Inhibition of hydroxymethylglutaryl-coenzyme A synthase by L-659, 699
17. Regulation of cytosolic acetoacetyl coenzyme A thiolase, 3-hydroxy-3-methylglutaryl coenzyme A synthase, 3-hydroxy-3-methylglutaryl coenzyme A reductase, and mevalonate kinase by low density lipoprotein and by 25-hydroxycholesterol in Chinese hamster ovary cells
18. Sterol-mediated regulation of mevalonic acid synthesis
19. Multiple blocks to human immunodeficiency virus type 1 replication in rodent cells
20. Virion incorporation of human immunodeficiency virus type 1 Nef is mediated by a bipartite membrane-targeting signal: Analysis of its role in enhancement of viral infectivity
21. Association of Nef with the human immunodeficiency virus type 1 core
22. Human immunodeficiency virus type 1 Nef associates with a member of the p21-activated kinase family
23. Activation of Vav by Nef induces cytoskeletal rearrangements and downstream effector functions
24. Activation of Ste20 by Nef from human immunodeficiency virus induces cytoskeletal rearrangements and downstream effector functions in Saccharomyces cerevisiae
25. Lovastatin inhibits HIV-1 expression in H9 human T lymphocytes cultured in cholesterol-poor medium
26. Membrane raft microdomains mediate lateral assemblies required for HIV-1 infection