Lipid rafts and HIV pathogenesis: Host membrane cholesterol is required for infection by HIV type 1

AIDS Research and Human Retroviruses

Volumn 17, Issue 11, 2001, Pages 1009-1019

  Liao, Zhaohao ^a   Cimakasky, Lisa M ^a   Hampton, Richard ^a   Nguyen, Dzung H ^a   Hildreth, James E K ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CYCLODEXTRIN; CD4 ANTIGEN; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4; CHOLESTEROL; INTERCELLULAR ADHESION MOLECULE 1; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; MEMBRANE LIPID; MONOCLONAL ANTIBODY; STROMAL CELL DERIVED FACTOR 1;

ANTIGEN BINDING; ANTIGEN EXPRESSION; ARTICLE; CELL ADHESION; CELL LEVEL; CELL LINE; CELL MEMBRANE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEPLETION; HOST CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOPATHOGENESIS; INCUBATION TIME; INFECTION RESISTANCE; INTERNALIZATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; RECEPTOR SENSITIVITY; SYNCYTIUM; VIRUS RESISTANCE;

BETA-CYCLODEXTRINS; CELL LINE; CHOLESTEROL; CYCLODEXTRINS; HIV INFECTIONS; HIV-1; HUMANS; JURKAT CELLS; MEMBRANE MICRODOMAINS; PROTEIN BINDING; RECEPTORS, CCR5; RECEPTORS, CXCR4; TUMOR CELLS, CULTURED;

EID: 0034834457     PISSN: 08892229     EISSN: None     Source Type: Journal    
DOI: 10.1089/088922201300343690     Document Type: Article

References (70)

1. Functional rafts in cell membranes
2. Cholesterol and sphingolipid enhance the Triton X-100 insolubility of glycosylphosphatidylinositol-anchored proteins by promoting the formation of detergent-insoluble ordered membrane domains
3. Separation of caveolae from associated microdomains of GPI-anchored proteins
4. Myristoylation and differential palmitoylation of the HCK protein-tyrosine kinases govern their attachment to membranes and association with caveolae
5. Differential regulation of Src-family tyrosine kinase in GPI domains of T lymphocyte plasma membranes
6. Endothelial nitrix oxide synthase targeting to caveolae. Specific interactions with caveolin isoforms in cardiac myocytes and endothelial cells
7. Determination of the non-ionic detergent insolubility and phosphoprotein associations of glycosylphosphatidylinositol-anchored proteins expressed on T cells
8. LAT palmitoylation: Its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation
9. Exclusion of CD45 inhibits activity of p56lck associated with glycolipid-enriched membrane domains
10. The amino-terminal nine amino acid sequence of poliovirus capsid VP4 protein is sufficient to confer N-myristoylation and targeting to detergent-insoluble membranes
11. Interaction of influenza virus haemagglutinin with sphingolipid-cholesterol membrane domains via its transmembrane domain
12. Functions of lipid rafts in biological membranes
13. T lymphocyte costimulation mediated by reorganization of membrane microdomains
14. Cholesterol depletion disrupts lipid rafts and modulates the activity of multiple signaling pathways in T lymphocytes
15. Perturbation of membrane microdomains reduces mitogenic signaling and increases susceptibility to apoptosis after T cell receptor stimulation
16. Tight junctions are membrane microdomains
17. HIV-1 entry cofactor: Functional cDNA cloning of a seven transmembrane, G protein-coupled receptor
18. Membrane cholesterol modulates galanin-Galr2 interaction
19. Cholesterol as modulator of receptor function
20. Human oxytocin receptors in cholesterol-rich vs. cholesterol-poor microdomains of the plasma membrane
21. Membrane fusion of Semliki Forest virus requires sphingolipids in the target membrane
22. A single point mutation controls the cholesterol dependence of Semliki Forest virus entry and exit
23. Membrane raft microdomains mediate front-rear polarity in migrating cells
24. Evidence for budding of human immunodeficiency virus type 1 selectively from glycolipid-enriched membrane lipid rafts
25. Cholesterol is required in the exit pathway of Semliki Forest virus
26. Influenza viruses select ordered lipid domains during budding from the plasma membrane
27. Measles virus structural components are enriched into lipid raft microdomains: A potential cellular location for virus assembly
28. Influenza virus assembly and lipid raft microdomains: A role for the cytoplasmic tails of the spike glycoproteins
29. Antibody to adhesion molecule LFA-1 enhances plasma neutralization of human immunodeficiency virus type 1
30. Increased infectivity of HIV type 1 particles bound to cell surface and solid-phase ICAM-1 and VCAM-1 through acquired adhesion molecules LFA-1 and VLA-4
31. Involvement of a leukocyte adhesion receptor (LFA-1) in HIV-induced syncytium formation
32. Association of host cell surface adhesion receptors and other membrane proteins with HIV and SIV
33. Cellular proteins bound to immunodeficiency viruses: Implications for pathogenesis and vaccines
34. Chemokines and the arrest of lymphocytes rolling under flow conditions
35. Integrin leukocyte function-associated antigen-1-mediated cell binding can be activated by clustering of membrane rafts
36. Role of cholesterol in formation and function of a signaling complex involving alphaVbeta3, integrin-associated protein (CD47), and heterotrimeric G proteins
37. Modulation of alpha5beta1 integrin functions by the phospholipid and cholesterol contents of cell membranes
38. T cell-tropic HIV gp120 mediates CD4 and CD8 cell chemotaxis through CXCR4 independent of CD4: Implications for HIV pathogenesis
39. LuSIV cells: A reporter cell line for the detection and quantitation of a single cycle of HIV and SIV replication
40. Cholesterol is required for infection by Semliki Forest virus
41. Semliki Forest virus budding: Assay, mechanisms, and cholesterol requirement
42. The cholesterol requirement for sindbis virus entry and exit and characterization of a spike protein region involved in cholesterol dependence
43. Low-pH-dependent fusion of sindbis virus with receptor-free cholesterol- and sphingolipid-containing liposomes
44. Membrane fusion induced by the HIV type 1 fusion peptide: Modulation by factors affecting glycoprotein 41 activity and potential anti-HIV compounds
45. Human erythrocyte glycolipids promote HIV-1 envelope glycoprotein-mediated fusion of CD4+ cells
46. Human erythrocyte glycosphingolipids as alternative cofactors for human immunodeficiency virus tpe 1 (HIV-1) entry: Evidence for CD4-induced interactions between HIV-1 gp120 and reconstituted membrane microdomains of glycosphingolipids (Gb3 and GM3)
47. Glycosphingolipids promote entry of a broad range of human immunodeficiency virus type 1 isolates into cell lines expressing CD4, CXCR4, and/or CCR5
48. Major histocompatibility complex class I molecules mediate association of SV40 with caveolae
49. The glycosylphosphatidylinositol-anchored surface glycoprotein Thy-1 is a receptor for the channel-forming toxin aerolysin
50. Clostridium septicum alpha toxin uses glycosylphosphatidylinositol-anchored protein receptors
51. Cholera toxin: Interactions of subunits with ganglioside GM1
52. Oligomerization of Vibrio cholerae cytolysin yields a pentameric pore and has a dual specificity for cholesterol and sphingolipids in the target membrane
53. The channel-forming toxin aerolysin neutralizes human immunodeficiency virus type 1
54. HIV acquires functional adhesion receptors from host cells
55. Host-derived ICAM-1 glycoproteins incorporated on human immunodeficiency virus type 1 are biologically active and enhance viral infectivity
56. CD4-negative cells bind human immunodeficiency virus type 1 and efficiently transfer virus to T cells
57. HIV-1-induced cell fusion is mediated by multiple regions within both the viral envelope and the CCR-5 co-receptor
58. A binding pocket for a small molecule inhibitor of HIV-1 entry within the transmembrane helices of CCR5
59. Inhibitory mechanism of the CXCR4 antagonist T22 against human immunodeficiency virus type 1 infection
60. Inhibition of G-protein-coupled receptor function by disruption of transmembrane domain interactions
61. Actin-dependent receptor colocalization required for human immunodeficiency virus entry into host cells
62. Polarization of chemokine receptors to the leading edge during lymphocyte chemotaxis
63. From TCR engagement to T cell activation: A kinetic view of T cell behavior
64. Acute cholesterol depletion inhibits clathrin-coated pit budding
65. Extraction of cholesterol with methyl-beta-cyclodextrin perturbs formation of clathrin-coated endocytic vesicles
66. Phorbol esters and SDF-1 induce rapid endocytosis and down modulation of the chemokine receptor CXCR4
67. Trafficking of the HIV coreceptor CXCR4: Role of arrestins and identification of residues in the C-terminal tail that mediate receptor internalization
68. Role of clathrin-mediated endocytosis in CXCR2 sequestration, resensitization, and signal transduction
69. Caveolin moves from caveolae to the Golgi apparatus in response to cholesterol oxidation
70. Membrane raft microdomains mediate lateral assemblies required for HIV-1 infection