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Volumn 15, Issue 1, 2001, Pages 43-58

The soluble interleukin 6 receptor: Mechanisms of production and implications in disease

Author keywords

Cytokines; Inflammation; Interleukin 6; Shedding; Soluble receptors

Indexed keywords

AUTACOID; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR;

EID: 0035164602     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.99-1003rev     Document Type: Review
Times cited : (552)

References (178)
  • 3
    • 0028171227 scopus 로고
    • Human atherosclerotic abdominal aortic aneurysms produce interleukin-6 and interferon-gamma, but not IL-2 and IL4: The possible role for interleukin-6 and interferon-gamma in vascular inflammation
    • (1994) Agents Actions , vol.42 , pp. 159-162
    • Szekanecz, Z.1    Shah, M.R.2    Pearce, W.H.3    Koch, A.E.4
  • 28
    • 0028279791 scopus 로고
    • Ciliary neurotrophic factor/leukemia inhibitory factor/interleukin 6/oncostatin M family of cytokines induces tyrosine phosphorylation of a common set of proteins overlapping those induced by other cytokines and growth factors
    • (1994) J. Biol. Chem. , vol.269 , pp. 11648-11655
    • Boulton, T.G.1    Stahl, N.2    Yancopoulos, G.D.3
  • 30
    • 0027996528 scopus 로고
    • Involvement of Janus kinase p52shc, Raf-1 and MEK-1 in the IL-6-induced mitogen-activated protein kinase cascade of a growth-responsive B-cell line
    • (1994) J. Immunol. , vol.153 , pp. 4436-4447
    • Kumar, G.1    Gupta, S.2    Wang, S.3    Nel, A.E.4
  • 32
    • 0028361695 scopus 로고
    • Association of p72 tyrosine kinase with STAT factors and its activation by interleukin-3, interleukin-6 and granulocyte colony stimulating factor
    • (1994) Blood , vol.83 , pp. 3457-3461
    • Matsuda, T.1    Hirano, T.2
  • 33
    • 0028215282 scopus 로고
    • Functional and biochemical association of Hck with the LIF/IL-6 receptor signal transducing subunit gp130 in embryonic stem cells
    • (1994) EMBO J. , vol.13 , pp. 1574-1584
    • Ernst, M.1    Gearing, D.P.2    Dunn, A.R.3
  • 39
    • 0029896751 scopus 로고    scopus 로고
    • A soluble interleukin-6 receptor isolated from conditioned medium of human breast cancer cells is encoded by a differentially spliced mRNA
    • (1996) Cytokine , vol.8 , pp. 401-409
    • Oh, J.W.1    Revel, M.2    Chebath, J.3
  • 46
    • 0025783528 scopus 로고
    • Homology of the p40 subunit of natural killer cell stimulatory factor (NKSF) with the extracellular domain of the interleukin-6 receptor
    • (1991) Cell , vol.66 , pp. 9-10
    • Gearing, D.P.1    Cosman, D.2
  • 91
    • 0029896751 scopus 로고    scopus 로고
    • A soluble interleukin-6 receptor isolated from conditioned medium of human breast cancer cells is encoded by a differentially spliced mRNA
    • (1996) Cytokine , vol.8 , pp. 401-409
    • Oh, J.W.1    Revel, M.2    Chebath, J.3
  • 113
    • 0020971452 scopus 로고
    • Acute phase proteins with special reference to C-reactive protein and related proteins (pentaxins) and serum amyloid A protein
    • (1983) Adv. Immunol. , vol.34 , pp. 141-212
    • Pepys, M.B.1    Baltz, M.L.2
  • 116
    • 0024538350 scopus 로고
    • Effects of C-reactive protein on human neutrophil granulocytes challenged with N-formyl-methionyl-leucyl-phenylalanine and platelet-activating factor
    • (1989) Life Sci. , vol.44 , pp. 517-524
    • Filep, J.1    Foldes-Filep, E.2
  • 163
    • 0032746822 scopus 로고    scopus 로고
    • Enhanced production of interleukin-6 (IL-6), oncostatin-M and soluble IL-6 receptor by cultured peripheral blood mononuclear cells from patients with systemic sclerosis
    • (1999) Rheumatology , vol.38 , pp. 612-617
    • Hasegawa, M.1    Sat, S.2    Ihn, H.3    Takehara, K.4
  • 174
    • 0032127276 scopus 로고    scopus 로고
    • Changes in sIL-6R and sTNF-Rs release by PMNs and the serum levels in breast cancer patients at different stages of treatment
    • (1998) Cytokine , vol.10 , pp. 540-543
    • Jablonska, E.1
  • 175
    • 0032933715 scopus 로고    scopus 로고
    • Relationship of serum levels of interleukin-6, soluble interleukin-6 receptor and tumour necrosis factor receptors to the acute-phase protein response in advanced pancreatic cancer
    • (1999) Clin. Sci. , vol.96 , pp. 83-87
    • Barber, M.D.1    Fearon, K.C.H.2    Ross, J.A.3
  • 177
    • 0031759773 scopus 로고    scopus 로고
    • Soluble interleukin-6 receptor, interleukin-10 and granulocyte colony-stimulating factor in acute pyelonephritis: Relationship to markers of bacterial virulence and renal function
    • (1998) Nephron , vol.80 , pp. 401-407
    • Jacobsen, S.H.1    Lu, Y.2    Brauner, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.