Humanized antibody to human interleukin-6 receptor inhibits the development of collagen arthritis in cynomolgus monkeys

Clinical Immunology

Volumn 98, Issue 3, 2001, Pages 319-326

  Mihara, Masahiko ^a   Kotoh, Masao ^a   Nishimoto, Norihiro ^c   Oda, Yasuhiro ^b   Kumagai, Eiji ^b   Takagi, Nobuhiro ^a   Tsunemi, Kunihiko ^a   Ohsugi, Yoshiyuki ^a   Kishimoto, Tadamitsu ^d   Yoshizaki, Kazuyuki ^c   Takeda, Yasuhisa ^a  

^a CHUGAI PHARMACEUTICAL CO LTD   (Japan)

^b CSK Research Park Inc   (Japan)

^c OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

^d OSAKA UNIVERSITY   (Japan)

Author keywords

Anti IL 6R antibody; Collagen arthritis; Monkey; Treatment

Indexed keywords

C REACTIVE PROTEIN; COLLAGEN; COLLAGEN ANTIBODY; FIBRINOGEN; INTERLEUKIN 6 RECEPTOR; INTERLEUKIN 6 RECEPTOR ANTIBODY; RECEPTOR ANTIBODY; UNCLASSIFIED DRUG;

ADOLESCENT; ANIMAL MODEL; ANIMAL TISSUE; ARTHRITIS; ARTICLE; CONTROLLED STUDY; ERYTHROCYTE SEDIMENTATION RATE; FEMALE; HISTOPATHOLOGY; INFLAMMATION; JOINT DESTRUCTION; JOINT RADIOGRAPHY; MACACA; MALE; NONHUMAN; PRIORITY JOURNAL;

EID: 0035090840     PISSN: 15216616     EISSN: None     Source Type: Journal    
DOI: 10.1006/clim.2000.4989     Document Type: Article

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