RX871024 induces Ca2+ mobilization from thapsigargin-sensitive stores in mouse pancreatic β-cells

Diabetes

Volumn 47, Issue 2, 1998, Pages 211-218

  Efanova, Ioulia B ^a,b   Zaitsev, Sergei V ^a,b   Brown, Graham ^a   Berggren, Per Olof ^a   Efendić, Suad ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b MOSCOW STATE UNIVERSITY   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CARBACHOL; CYTOCHROME P450; GLIBENCLAMIDE; IMIDAZOLINE DERIVATIVE; ION CHANNEL; PHENTOLAMINE; RX 871024; THAPSIGARGIN; UNCLASSIFIED DRUG; 2 (2 IMIDAZOLIN 2 YL) 1 PHENYL 1H INDOLE; 2-(2-IMIDAZOLIN-2-YL)-1-PHENYL-1H-INDOLE; ADENOSINE TRIPHOSPHATASE (CALCIUM); ADENOSINE TRIPHOSPHATE; ANTIDIABETIC AGENT; CALCIUM; CALCIUM CHANNEL; ENZYME INHIBITOR; GLUTATHIONE; IMIDAZOLE DERIVATIVE; INDOLE DERIVATIVE; MONOAMINE OXIDASE INHIBITOR; POTASSIUM CHANNEL;

ANIMAL CELL; ARTICLE; CALCIUM MOBILIZATION; CONTROLLED STUDY; DRUG MECHANISM; INSULIN RELEASE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATION REDUCTION REACTION; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; ANIMAL; CHANNEL GATING; DRUG ANTAGONISM; DRUG EFFECT; ENDOPLASMIC RETICULUM; ENZYMOLOGY; METABOLISM; MOUSE MUTANT; PANCREAS ISLET; PHYSIOLOGY;

ADENOSINE TRIPHOSPHATE; ANIMALS; CALCIUM; CALCIUM CHANNELS; CALCIUM-TRANSPORTING ATPASES; CYTOCHROME P-450 ENZYME SYSTEM; ENDOPLASMIC RETICULUM; ENZYME INHIBITORS; GLUTATHIONE; GLYBURIDE; HYPOGLYCEMIC AGENTS; IMIDAZOLES; INDOLES; ION CHANNEL GATING; ISLETS OF LANGERHANS; MICE; MICE, OBESE; MONOAMINE OXIDASE INHIBITORS; OXIDATION-REDUCTION; POTASSIUM CHANNELS; THAPSIGARGIN;

EID: 0031594371     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diab.47.2.211     Document Type: Article

References (48)

1. 2+ and pancreatic β-cell function. Biochem Soc Trans 22:12-18, 1994
2. Rajan AS, Aguilar-Bryan L, Nelson DA, Yaney GC, Hsu WH, Kunze DL, Boyd AE III: Ion channels and insulin secretion. Diabetes Care 13:340-363, 1990
3. 2+, cAMP and diacylglycerol. Mol Cell Endocrinol 70:119-137, 1990
4. Howell SL, Jones PM, Persaud SJ: Regulation of insulin secretion: the role of second messengers. Diabetologia 37 (Suppl. 1):S30-S35, 1994
5. 2+ concentration and insulin secretion as evidenced from measurements in mouse single pancreatic islets. Proc Natl Acad Sci USA 92:9412-9416, 1995
6. 2+ and insulin release in carbamylcholine-stimulated RINm5F cells. J Biol Chem 261:8314-8319, 1986
7. 2+ concentration in pancreatic β-cells. Biochem J 321:347-354, 1996
8. 2+ release in insulinsecreting cells. FEBS Lett 296:287-291, 1992
9. Takasawa S, Nata K, Yonekura H, Okamoto H: Cyclic ADP-ribose in insulin secretion from pancreatic beta cells. Science 259:370-373, 1993
10. Galione A: Cyclic ADP-ribose: a new way to control calcium. Science 259:325-326, 1993
11. Islam MS, Larsson O, Berggren PO: Cyclic ADP-ribose and pancreatic beta cells. Science 262:584-586, 1993
12. 2+ stores in insulin-secreting cells: lack of effect of cADP ribose. Cell Calcium 16:71-80, 1994
13. 2+ concentration in the pancreatic β-cell are independent of cyclic ADP-ribose. J Biol Chem 271:19074-19079, 1996
14. Schulz A, Hasselblatt A: An insulin-releasing property of imidazoline derivatives is not limited to compounds that block alpha-adrenoceptors. Naunyn Schmiedebergs Arch Pharmacol 340:321-327, 1989
15. Östenson CG, Cattaneo AG, Doxey JC, Efendić S: Alpha-adrenoceptors and insulin release from pancreatic islets of normal and diabetic rats. Am J Physiol 257:E439-E443, 1989
16. 2-sites. Br J Pharmacol 112:1065-1070, 1994
17. ATP channels and interaction with exocytotic machinery. Diabetes 45:1610-1618, 1996
18. + channels in mouse pancreatic β-cells. Br J Pharmacol 101:115-120, 1990
19. + channels in pancreatic beta-cells. Br J Pharmacol 107:8-14, 1992
20. ATP channels in insulin secreting cells. Eur J Pharmacol 204:41-48, 1991
21. Chan SLF, Morgan NG: Stimulation of insulin secretion by efaroxan may involve interaction with potassium channels. Eur J Pharmacol 176:97-101, 1990
22. + channels in pancreatic B-cells. Exp Clin Endocrinol Diabetes 103 (Suppl. 2):S42-S45, 1995
23. Shepherd RM, Hashmi MN, Kane C, Squires PE, Dunne MJ: Elevation of cytosolic calcium by imidazolines in mouse islets of Langerhans: implications for stimulus-response coupling of insulin release. Br J Pharmacol 119:911-916, 1996
24. Lernmark Å: The preparation of, and studies on, free cell suspensions from mouse pancreatic islets. Diabetologia 10:431-438, 1974
25. 2+ in the pancreatic β-cells. FEBS Lett 303:85-90, 1992
26. 2+ and cyclic AMP in addition to inhibiting protein kinase C in rat islets of Langerhans. Mol Cell Endocrinol 94:55-60, 1993
27. 2+-ATPase. Proc Natl Acad Sci USA 87:2466-2470, 1990
28. 2+ release channel from skeletal muscle sarcoplasmic reticulum. J Biol Chem 270:25557-25563, 1995
29. 2+-ATPase activity of cardiac sarcoplasmic reticulum. Arch. Biochem. Biophys 261:447-457, 1988
30. Jensen GL, Meister A: Radioprotection of human lymphoid cells by exogenously supplied glutathione is mediated by gamma-glutamyl transpeptidase. Proc Natl Acad Sci USA 80:4714-4717, 1983
31. Mathews JM, Postal LA, Bend JR: Inactivation of rabbit pulmonary cytochrome P-450 in microsomes and isolated perfused lungs by the suicide substrate 1-aminobenzotriazole. J Pharmacol Exp Ther 235:186-190, 1985
32. 2+ mobilization by arachidonic acid: comparison with myo-inositol 1,4,5-triphosphate in isolated pancreatic islets. J Biol Chem 261:3501-3511, 1986
33. Taylor JD, Wykes AA, Gladish YC, Martin WB: New inhibitor of monoamine oxidase. Nature 187:941-942, 1960
34. Hall DWR, Logan BW, Parsons GH: Further studies on the inhibition of monoamine oxidase by M and B 9302 (clorgyline). I. Substrate specificity in various mammalian species. Biochem Pharmacol 18:1447-1454, 1969
35. + currents in pancreatic β-cells. Naunyn Schmiedebergs Arch Pharmacol 337:225-230, 1988
36. Singer TP, Ramsay RR: Flauoprotein structure and mechanism. 2. Monoamine oxidases: old friends hold many surprises. FASEB J 9:605-610, 1995
37. Dupont H, Davies DS, Strolin-Benedetti M: Inhibition of cytochrome P-450-dependent oxidation reactions by MAO inhibitors in rat liver microsomes. Biochem Pharmacol 36:1651-1657, 1987
38. Valoti M, Costanzo M, Perez V, Unzeta M, Sgaragli GP: Interactions between substituted tryptamine analogues, MAO inhibitors and cytochrome P-450. J Neur Transmis 41:291-293, 1994
39. Prasad JS, Erickson RR, Crankshaw DL, Holtzman JL: The effect of cytochrome P-450 and reduced glutathione on the ATP-dependent calcium pump of hepatic microsomes from male rats. Arch Biochem. Biophys 248:539-645, 1986
40. Mauger JP, Lievremont JP, Pietri-Rouxel F, Hilly M, Coquil JF: The inositol 1,4,5-triphosphate receptor kinetic properties and regulation. Mol Cell Endocrinol 98:133-139, 1994
41. 2+-ATPase by cAMP-dependent and tyrosine phosphorylation. J Biol Chem 272:15113-15119, 1997
42. 2+ efflux. Biochem Biophys Res Commun 165: 416-421, 1989
43. Nishimura T, Akasu T: Do calcium-induced calcium release and calcium pump cooperate to generate spontaneous oscillation of membrane current in mammalian neurons? Biomed Res 14 (Suppl. 2):39-41, 1993
44. 2+ release in smooth muscle cells of the guinea pig taenia caeci. J Gen Physiol 95:1103-1122, 1990
45. 3- and calcium-gated channels from endoplasmic reticulum of cerebellum. Nature 351:751-754, 1991
46. Iino M, Tsukioka M: Feedback control of inositol trisphosphate signalling by calcium. Mol Cell Endocrinol 98:141-146, 1994
47. 2+. Neuroscience 73:1061-1067, 1996
48. 2+ increases the affinity of inositol 1,4,5-trisphosphate for its receptor. Biochem J 292:631-633, 1993