메뉴 건너뛰기




Volumn 47, Issue 2, 1998, Pages 129-140

Expression of multiple apoptosis-regulatory genes in human breast cancer cell lines and primary tumors

Author keywords

Apoptosis; BAG 1; Bak; Bax; Bcl 2; Bcl X(L); Breast cell lines; Breast tumors; Caspase 3; Mcl 1

Indexed keywords

CASPASE 3; INTERLEUKIN 1BETA CONVERTING ENZYME; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; UNCLASSIFIED DRUG;

EID: 0031964133     PISSN: 01676806     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1005940832123     Document Type: Article
Times cited : (107)

References (41)
  • 1
    • 0017167185 scopus 로고
    • The clonal evolution of tumor cell populations
    • Nowell PC: The clonal evolution of tumor cell populations. Science 194: 23-28, 1976
    • (1976) Science , vol.194 , pp. 23-28
    • Nowell, P.C.1
  • 2
    • 0028040019 scopus 로고
    • Bcl-2 and the regulation of programmed cell death
    • Reed JC: Bcl-2 and the regulation of programmed cell death. J Cell Biol 124: 1-6, 1994
    • (1994) J Cell Biol , vol.124 , pp. 1-6
    • Reed, J.C.1
  • 3
    • 0028958030 scopus 로고
    • Bcl-2: Prevention of apoptosis as a mechanism of drug resistance
    • Reed JC: Bcl-2: Prevention of apoptosis as a mechanism of drug resistance. Hematology/Oncology Clinics of North America 9: 451-474, 1995
    • (1995) Hematology/Oncology Clinics of North America , vol.9 , pp. 451-474
    • Reed, J.C.1
  • 4
    • 0028326952 scopus 로고
    • An evolutionary perspective on apoptosis
    • Vaux DL, Haecker G, Strasser A: An evolutionary perspective on apoptosis. Cell 76: 777-779, 1994
    • (1994) Cell , vol.76 , pp. 777-779
    • Vaux, D.L.1    Haecker, G.2    Strasser, A.3
  • 5
    • 0028972616 scopus 로고
    • Regulation of apoptosis by Bcl-2 family proteins and its role in cancer and chemoresistance
    • Reed JC: Regulation of apoptosis by Bcl-2 family proteins and its role in cancer and chemoresistance. Curr Opin Oncol 7:541-546, 1995
    • (1995) Curr Opin Oncol , vol.7 , pp. 541-546
    • Reed, J.C.1
  • 6
    • 0029927422 scopus 로고    scopus 로고
    • The role of proteases during apoptosis
    • Patel T, Gores GJ, Kaufmann SH: The role of proteases during apoptosis. FASEB J 10: 587-597, 1996
    • (1996) FASEB J , vol.10 , pp. 587-597
    • Patel, T.1    Gores, G.J.2    Kaufmann, S.H.3
  • 7
    • 0029955620 scopus 로고    scopus 로고
    • Flow cytometry analysis of apoptosis and Bcl-2 in primary breast carcinomas: Clinical and biological implications
    • Steck S, McDonnell T, Sneige N, El-Naggar A: Flow cytometry analysis of apoptosis and Bcl-2 in primary breast carcinomas: clinical and biological implications. Cytometry 24: 116-122, 1996
    • (1996) Cytometry , vol.24 , pp. 116-122
    • Steck, S.1    McDonnell, T.2    Sneige, N.3    El-Naggar, A.4
  • 9
    • 0029007175 scopus 로고
    • Effects of estrogen on apoptotic pathways in human breast cancer cell line MCF-7
    • Wang TTY, Phang JM: Effects of estrogen on apoptotic pathways in human breast cancer cell line MCF-7. Cancer Res 55: 2487-2489, 1995
    • (1995) Cancer Res , vol.55 , pp. 2487-2489
    • Wang, T.T.Y.1    Phang, J.M.2
  • 10
    • 0030008732 scopus 로고    scopus 로고
    • p53-independent apoptosis during mammary tumor progression in C3(1)/SV40 large T antigen transgenic mice: Suppression of apoptosis during the transition from preneoplasia to carcinoma
    • Shibata M-A, Maroulakou IG, Jorcyk CL, Gold LG, Ward JM, Green JE: p53-independent apoptosis during mammary tumor progression in C3(1)/SV40 large T antigen transgenic mice: suppression of apoptosis during the transition from preneoplasia to carcinoma. Cancer Res 56: 2998-3003, 1996
    • (1996) Cancer Res , vol.56 , pp. 2998-3003
    • Shibata, M.-A.1    Maroulakou, I.G.2    Jorcyk, C.L.3    Gold, L.G.4    Ward, J.M.5    Green, J.E.6
  • 14
    • 0028883179 scopus 로고
    • Tumor suppressor p53 is a direct transcriptional activator of human bax gene
    • Miyashita T, Reed JC: Tumor suppressor p53 is a direct transcriptional activator of human bax gene. Cell 80: 293-299, 1995
    • (1995) Cell , vol.80 , pp. 293-299
    • Miyashita, T.1    Reed, J.C.2
  • 15
    • 0029045784 scopus 로고
    • Reduced expression of pro-apoptotic gene Bax is associated with poor response rates to combination chemotherapy and shorter survival in women with metastatic breast adenocarcinoma
    • Krajewski S, Blomvqvist C, Franssila K, Krajewska M, Wasenius V-M, Niskanen E, Reed JC: Reduced expression of pro-apoptotic gene Bax is associated with poor response rates to combination chemotherapy and shorter survival in women with metastatic breast adenocarcinoma. Cancer Res 55: 4471-4478, 1995
    • (1995) Cancer Res , vol.55 , pp. 4471-4478
    • Krajewski, S.1    Blomvqvist, C.2    Franssila, K.3    Krajewska, M.4    Wasenius, V.-M.5    Niskanen, E.6    Reed, J.C.7
  • 16
    • 0028814112 scopus 로고
    • Immunohistochemical analysis of the Bcl-2 oncoprotein in human neuroblastoma
    • Krajewski S, Chatten J, Hanada M, Womer R, Reed JC: Immunohistochemical analysis of the Bcl-2 oncoprotein in human neuroblastoma. Lab Invest 71: 42-54, 1995
    • (1995) Lab Invest , vol.71 , pp. 42-54
    • Krajewski, S.1    Chatten, J.2    Hanada, M.3    Womer, R.4    Reed, J.C.5
  • 17
    • 0028847915 scopus 로고
    • Cloning and functional analysis of BAG-1: A novel Bcl-2 binding protein with anti-cell death activity
    • Takayama S, Sato T, Krajewski S, Kochel K, Irie S, Millan JA, Reed JC: Cloning and functional analysis of BAG-1: a novel Bcl-2 binding protein with anti-cell death activity. Cell 80: 279-284, 1995
    • (1995) Cell , vol.80 , pp. 279-284
    • Takayama, S.1    Sato, T.2    Krajewski, S.3    Kochel, K.4    Irie, S.5    Millan, J.A.6    Reed, J.C.7
  • 18
    • 0028927484 scopus 로고
    • Suppression of ICE and apoptosis in mammary epithelial cells by extracellular matrix
    • Boudreau N, Sympson CJ, Werb Z, Bissell MJ: Suppression of ICE and apoptosis in mammary epithelial cells by extracellular matrix. Science 267: 891-893, 1995
    • (1995) Science , vol.267 , pp. 891-893
    • Boudreau, N.1    Sympson, C.J.2    Werb, Z.3    Bissell, M.J.4
  • 19
    • 0027956645 scopus 로고
    • Immunohistochemical analysis of mcl-1 and bcl-2 proteins in normal and neoplastic lymph nodes
    • Krajewski S, Bodrug S, Gascoyne R, Berean K, Krajewska M, Reed JC: Immunohistochemical analysis of mcl-1 and bcl-2 proteins in normal and neoplastic lymph nodes. Amer J Pathol 145: 515-525, 1994
    • (1994) Amer J Pathol , vol.145 , pp. 515-525
    • Krajewski, S.1    Bodrug, S.2    Gascoyne, R.3    Berean, K.4    Krajewska, M.5    Reed, J.C.6
  • 21
    • 0029990550 scopus 로고    scopus 로고
    • Immunohistochemical analysis of in vivo patterns of Bak expression, a pro-apoptotic member of the Bcl-2 protein family
    • Krajewski S, Krajewska M, Reed JC: Immunohistochemical analysis of in vivo patterns of Bak expression, a pro-apoptotic member of the Bcl-2 protein family. Cancer Res 56: 2849-2855, 1996
    • (1996) Cancer Res , vol.56 , pp. 2849-2855
    • Krajewski, S.1    Krajewska, M.2    Reed, J.C.3
  • 23
    • 0026165368 scopus 로고
    • Differential regulation of the p72-74 Raf-1 kinase by RAS and SRC oncoproteins
    • Reed JC, Yum S, Cuddy MP, Turner BC, Rapp UR: Differential regulation of the p72-74 Raf-1 kinase by RAS and SRC oncoproteins. Cell Growth & Diff 2: 235-243, 1991
    • (1991) Cell Growth & Diff , vol.2 , pp. 235-243
    • Reed, J.C.1    Yum, S.2    Cuddy, M.P.3    Turner, B.C.4    Rapp, U.R.5
  • 24
  • 25
    • 0029979249 scopus 로고    scopus 로고
    • Detection of multiple antigens on Western blots
    • Krajewski S, Zapata JM, Reed JC: Detection of multiple antigens on Western blots. Anal Biochem 236: 221-228, 1996
    • (1996) Anal Biochem , vol.236 , pp. 221-228
    • Krajewski, S.1    Zapata, J.M.2    Reed, J.C.3
  • 26
    • 0028036895 scopus 로고
    • Immunohistochemical determination of in vivo distribution of bax, a dominant inhibitor of bcl-2
    • Krajewski S, Krajewska M, Shabaik A, Miyashita T, Wang H-G, Reed JC: Immunohistochemical determination of in vivo distribution of bax, a dominant inhibitor of bcl-2. Am J Pathol 145: 1323-1333, 1994
    • (1994) Am J Pathol , vol.145 , pp. 1323-1333
    • Krajewski, S.1    Krajewska, M.2    Shabaik, A.3    Miyashita, T.4    Wang, H.-G.5    Reed, J.C.6
  • 29
    • 0025367297 scopus 로고
    • Genetic and immunochemical analysis of mutant p53 in human breast cancer cell lines
    • Bartek J, Iggo R, Gannon J, Lane DP: Genetic and immunochemical analysis of mutant p53 in human breast cancer cell lines. Oncogene 5: 893-899, 1990
    • (1990) Oncogene , vol.5 , pp. 893-899
    • Bartek, J.1    Iggo, R.2    Gannon, J.3    Lane, D.P.4
  • 32
    • 0030960657 scopus 로고    scopus 로고
    • Immunohistochemical analysis of in vivo patterns of expression of CPP32 (Caspase-3), a cell death protease
    • Krajewska M, Wang H-G, Krajewski S, Zapata J, Shahaik A, Gascoyne R, Reed JC: Immunohistochemical analysis of in vivo patterns of expression of CPP32 (Caspase-3), a cell death protease. Cancer Res 57: 1605-1613, 1997
    • (1997) Cancer Res , vol.57 , pp. 1605-1613
    • Krajewska, M.1    Wang, H.-G.2    Krajewski, S.3    Zapata, J.4    Shahaik, A.5    Gascoyne, R.6    Reed, J.C.7
  • 33
    • 0030162560 scopus 로고    scopus 로고
    • Balancing cell life and death: Bax, apoptosis, and breast cancer
    • Reed JC: Balancing cell life and death: Bax, apoptosis, and breast cancer. J Clin Invest 97: 2403-2404, 1996
    • (1996) J Clin Invest , vol.97 , pp. 2403-2404
    • Reed, J.C.1
  • 34
    • 0026054909 scopus 로고
    • Growth suppression of human breast cancer cells by the introduction of a wild-type p53 gene
    • Casey G, Lo-Hsueh M, Lopez ME, Vogelstein B, Stanbridge EJ: Growth suppression of human breast cancer cells by the introduction of a wild-type p53 gene. Oncogene 6: 1791-1797, 1991
    • (1991) Oncogene , vol.6 , pp. 1791-1797
    • Casey, G.1    Lo-Hsueh, M.2    Lopez, M.E.3    Vogelstein, B.4    Stanbridge, E.J.5
  • 36
    • 0028944271 scopus 로고
    • Expression of the bcl-2 gene family in normal and malignant breast tissue: Low bax-α expression in tumor cells correlates with resistance towards apoptosis
    • Bargou RC, Daniel PT, Mapara MY, Bommert K, Wagener C, Kallinich B, Royer HD, Dörken B: Expression of the bcl-2 gene family in normal and malignant breast tissue: low bax-α expression in tumor cells correlates with resistance towards apoptosis. Int J Cancer 60: 854-859, 1995
    • (1995) Int J Cancer , vol.60 , pp. 854-859
    • Bargou, R.C.1    Daniel, P.T.2    Mapara, M.Y.3    Bommert, K.4    Wagener, C.5    Kallinich, B.6    Royer, H.D.7    Dörken, B.8
  • 37
    • 0030062205 scopus 로고    scopus 로고
    • Induction of the death-promoting gene bax-alpha sensitizes cultured breast-cancer cells to drug-induced apoptosis
    • Wagener C, Bargou RC, Daniel PT, Bommert K, Mapara MY, Royer HD, Dörken B: Induction of the death-promoting gene bax-alpha sensitizes cultured breast-cancer cells to drug-induced apoptosis. Int J Cancer 67: 138-141, 1996
    • (1996) Int J Cancer , vol.67 , pp. 138-141
    • Wagener, C.1    Bargou, R.C.2    Daniel, P.T.3    Bommert, K.4    Mapara, M.Y.5    Royer, H.D.6    Dörken, B.7
  • 40
    • 0029614713 scopus 로고
    • A protein that interacts with members of the nuclear hormone receptor family: Identification and cDNA cloning
    • Zeinet M, Gehring U: A protein that interacts with members of the nuclear hormone receptor family: identification and cDNA cloning. Proc Natl Acad Sci USA 92: 11465-11469, 1995
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 11465-11469
    • Zeinet, M.1    Gehring, U.2
  • 41
    • 0029937303 scopus 로고    scopus 로고
    • Bcl-2 interacting protein, BAG-1, binds to and activates the kinase Raf-1
    • Wang H-G, Takayama S, Rapp UR, Reed JC: Bcl-2 interacting protein, BAG-1, binds to and activates the kinase Raf-1. Proc Natl Acad Sci USA 93: 7063-7068, 1996
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 7063-7068
    • Wang, H.-G.1    Takayama, S.2    Rapp, U.R.3    Reed, J.C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.