Estrogens and ICI182,780 (Faslodex) modulate mitosis and cell death in immature cerebellar neurons via rapid activation of p44/p42 mitogen-activated protein kinase

Journal of Neuroscience

Volumn 23, Issue 12, 2003, Pages 4984-4995

  Wong, Jeremy K ^b,c   Le, Hoa H ^a   Zsarnovszky, Attila ^a   Belcher, Scott M ^a,b  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^c JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Cerebellum; Development; ERK; Estradiol; Estrogen; Granule cell; MAPK; Necrosis; Neuron; Neurotoxicity; Oncosis

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 17ALPHA ESTRADIOL; ANTIMITOTIC AGENT; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; BOVINE SERUM ALBUMIN; BROXURIDINE; CALPASTATIN; CASPASE INHIBITOR; ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR; FULVESTRANT; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PD 150606; PROGESTERONE; PROTEIN P42; PROTEIN P44; TESTOSTERONE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CELL MEMBRANE PERMEABILITY; CELL VIABILITY; CEREBELLUM; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOLYSIS; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FEMALE; GENE EXPRESSION REGULATION; GRANULE CELL; INTRACELLULAR TRANSPORT; MALE; MITOSIS; NERVOUS SYSTEM FUNCTION; NEUROBLAST; NEUROTOXICITY; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

EID: 0038790428     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.23-12-04984.2003     Document Type: Article

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