-
1
-
-
0003060912
-
Retinoids and cancer in experimental animals
-
H. M. Sporn, A. B. Roberts, and D. S. Goodman (eds.), New York: Raven Press
-
Moon, R. C., Mehta, R. G., and Rao, K. J. V. N. Retinoids and cancer in experimental animals. In: H. M. Sporn, A. B. Roberts, and D. S. Goodman (eds.), The Retinoids, pp. 573-595. New York: Raven Press, 1994.
-
(1994)
The Retinoids
, pp. 573-595
-
-
Moon, R.C.1
Mehta, R.G.2
Rao, K.J.V.N.3
-
2
-
-
0001319804
-
Retinoids and human cancer
-
H. M. Sporn, A. B. Roberts, and D. S. Goodman (eds.), New York: Raven Press
-
Hong, W. K., and Itri, L. M. Retinoids and human cancer. In: H. M. Sporn, A. B. Roberts, and D. S. Goodman (eds.), The Retinoids, pp. 597-658. New York: Raven Press, 1994.
-
(1994)
The Retinoids
, pp. 597-658
-
-
Hong, W.K.1
Itri, L.M.2
-
3
-
-
0029796637
-
Retinoids in cancer chemoprevention
-
Lotan, R. Retinoids in cancer chemoprevention. FASEB J., 10: 1031-1039, 1996.
-
(1996)
FASEB J.
, vol.10
, pp. 1031-1039
-
-
Lotan, R.1
-
4
-
-
0032955702
-
Retinoids: Present role and future potential
-
Evans, T. R. J., and Kaye, S. Retinoids: present role and future potential. Br. J. Cancer, 80: 1-8, 1999.
-
(1999)
Br. J. Cancer
, vol.80
, pp. 1-8
-
-
Evans, T.R.J.1
Kaye, S.2
-
5
-
-
0002020447
-
The Cellular biology and biochemistry of the retinoids
-
H. M. Sporn, A. B. Roberts, and D. S. Goodman (eds.), New York: Raven Press
-
Gudas, L. J., Sporn, M. B., and Roberts, A. B. The Cellular biology and biochemistry of the retinoids. In: H. M. Sporn, A. B. Roberts, and D. S. Goodman (eds.), The Retinoids, pp. 443-520. New York: Raven Press, 1994.
-
(1994)
The Retinoids
, pp. 443-520
-
-
Gudas, L.J.1
Sporn, M.B.2
Roberts, A.B.3
-
6
-
-
0030065518
-
The efficacy of 9-cis-retinoic acid in experimental models of cancer
-
Gottardis, M. M., Lamph, W. W., Shalinsky, D. R., Wellstein, A., and Heyman, R. A. The efficacy of 9-cis-retinoic acid in experimental models of cancer. Breast Cancer Res. Treat., 38: 85-96, 1996.
-
(1996)
Breast Cancer Res. Treat.
, vol.38
, pp. 85-96
-
-
Gottardis, M.M.1
Lamph, W.W.2
Shalinsky, D.R.3
Wellstein, A.4
Heyman, R.A.5
-
7
-
-
0031015054
-
A novel retinoic acid receptor-selective retinoid. ALRT1550, has potent antitumor activity against human oral squamous carcinoma xenografts in nude mice
-
Shalinsky, D. R., Bischoff, E. D., Lamph, W. W., Zhang, L., Boehm, M. F., Davies, P. J., Nadzan, A. M., and Heyman, R. A. A novel retinoic acid receptor-selective retinoid. ALRT1550, has potent antitumor activity against human oral squamous carcinoma xenografts in nude mice. Cancer Res., 57: 162-168, 1997.
-
(1997)
Cancer Res.
, vol.57
, pp. 162-168
-
-
Shalinsky, D.R.1
Bischoff, E.D.2
Lamph, W.W.3
Zhang, L.4
Boehm, M.F.5
Davies, P.J.6
Nadzan, A.M.7
Heyman, R.A.8
-
8
-
-
0032006028
-
Beyond tamoxifen: The retinoid X receptor-selective ligand LGD1069 (TARGRETIN) causes complete regression of mammary carcinoma
-
Bischoff, E. D., Gottardis, M. M., Moon, T. E., Heyman, R. A., and Lamph, W. W. Beyond tamoxifen: the retinoid X receptor-selective ligand LGD1069 (TARGRETIN) causes complete regression of mammary carcinoma. Cancer Res., 58: 479-484, 1998.
-
(1998)
Cancer Res.
, vol.58
, pp. 479-484
-
-
Bischoff, E.D.1
Gottardis, M.M.2
Moon, T.E.3
Heyman, R.A.4
Lamph, W.W.5
-
9
-
-
0029970608
-
Enhanced antitumor efficacy of cisplatin in combination with ALRT1057 (9-cis retinoic acid) in human oral squamous carcinoma xenografts in nude mice
-
Shalinsky, D. R., Bischoff, E. D., Gregory, M. L., Lamph, W. W., Heyman, R. A., Hayes, J. S., Thomazy, V., and Davies, P. J. Enhanced antitumor efficacy of cisplatin in combination with ALRT1057 (9-cis retinoic acid) in human oral squamous carcinoma xenografts in nude mice. Clin. Cancer. Res., 3: 511-520, 1996.
-
(1996)
Clin. Cancer. Res.
, vol.3
, pp. 511-520
-
-
Shalinsky, D.R.1
Bischoff, E.D.2
Gregory, M.L.3
Lamph, W.W.4
Heyman, R.A.5
Hayes, J.S.6
Thomazy, V.7
Davies, P.J.8
-
10
-
-
0028256280
-
Suppression of squamous cell carcinoma growth and differentiation by retinoids
-
Lotan, R. Suppression of squamous cell carcinoma growth and differentiation by retinoids. Cancer Res., 54 (Suppl.): 1987s-1990s, 1994.
-
(1994)
Cancer Res.
, vol.54
, Issue.SUPPL.
-
-
Lotan, R.1
-
11
-
-
0029934858
-
Reconstituted basement membrane (Matrigel): A useful semisolid medium for growth of tumor cell colonies
-
Oridate, N., Lotan, R., and Lotan, D. Reconstituted basement membrane (Matrigel): a useful semisolid medium for growth of tumor cell colonies. In Vitro Cell Dev. Biol. Anim., 4: 192-193, 1994.
-
(1994)
In Vitro Cell Dev. Biol. Anim.
, vol.4
, pp. 192-193
-
-
Oridate, N.1
Lotan, R.2
Lotan, D.3
-
12
-
-
0027353845
-
Squamous cell differentiation markers in normal, premalignant, and malignant epithelium: Effects of retinoids
-
Lotan, R. Squamous cell differentiation markers in normal, premalignant, and malignant epithelium: effects of retinoids. J. Cell. Biochem. Suppl., 17: 167-174, 1993.
-
(1993)
J. Cell. Biochem. Suppl.
, vol.17
, pp. 167-174
-
-
Lotan, R.1
-
13
-
-
0034048911
-
Identification of receptor-selective retinoids that are potent inhibitors of the growth of human head and neck squamous cell carcinoma cells
-
Sun, S-Y., Yue, P., Mao, L., Dawson, M. I., Shroot, B., Lamph, W. W., Heyman, R. A., Chandraratna, R. A. S., Shudo, K., Hong, W. K., and Lotan, R. Identification of receptor-selective retinoids that are potent inhibitors of the growth of human head and neck squamous cell carcinoma cells. Clin. Cancer Res., 6: 1563-1573, 2000.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 1563-1573
-
-
Sun, S.-Y.1
Yue, P.2
Mao, L.3
Dawson, M.I.4
Shroot, B.5
Lamph, W.W.6
Heyman, R.A.7
Chandraratna, R.A.S.8
Shudo, K.9
Hong, W.K.10
Lotan, R.11
-
14
-
-
0033563006
-
Mediation of N-(4-hydoxyphenyl) retinamide-induced apoptosis in human cancer cells by different mechanisms
-
Sun, S-Y., Li, W., Yue, P., Hong, W. K., and Lotan, R. Mediation of N-(4-hydoxyphenyl) retinamide-induced apoptosis in human cancer cells by different mechanisms. Cancer Res., 59: 2493-2498, 1999.
-
(1999)
Cancer Res.
, vol.59
, pp. 2493-2498
-
-
Sun, S.-Y.1
Li, W.2
Yue, P.3
Hong, W.K.4
Lotan, R.5
-
15
-
-
12644304208
-
Chemoprevention of breast cancer with fenretinide (4-HPR): Study of long-term visual and ophthalmologic tolerability
-
Mariani, L., Formelli, F., De Palo, G., Manzari, A., Camerini, T., Campa, T., Di Mauro, M. G., Crippa, A., Delle Grottaglie, M., Del Vecchio, M., Marubini, E., Costa, A., and Veronesi, U. Chemoprevention of breast cancer with fenretinide (4-HPR): study of long-term visual and ophthalmologic tolerability. Tumorigenesis, 82: 444-449, 1996.
-
(1996)
Tumorigenesis
, vol.82
, pp. 444-449
-
-
Mariani, L.1
Formelli, F.2
De Palo, G.3
Manzari, A.4
Camerini, T.5
Campa, T.6
Di Mauro, M.G.7
Crippa, A.8
Delle Grottaglie, M.9
Del Vecchio, M.10
Marubini, E.11
Costa, A.12
Veronesi, U.13
-
16
-
-
25444496872
-
Refining retinoids with heteroatoms
-
Benbrook, D. M. Refining retinoids with heteroatoms. Minirev. Med. Chem., 2: 271-277, 2002.
-
(2002)
Minirev. Med. Chem.
, vol.2
, pp. 271-277
-
-
Benbrook, D.M.1
-
18
-
-
0035155756
-
Synergistic teratogenic effects induced by retinoids in mice by coadministration of a RARα- or RARγ-selective agonist with a RXR-selective agonist
-
Elmazar, M. M., Ruhl, R., and Nau, H. Synergistic teratogenic effects induced by retinoids in mice by coadministration of a RARα- or RARγ-selective agonist with a RXR-selective agonist. Toxicol. Appl. Pharmacol., 170: 2-9, 2001.
-
(2001)
Toxicol. Appl. Pharmacol.
, vol.170
, pp. 2-9
-
-
Elmazar, M.M.1
Ruhl, R.2
Nau, H.3
-
19
-
-
9844266252
-
Biologically active heteroarotinoids exhibiting anticancer activity and decreased toxicity
-
Benbrook, D. M., Madler, M. M., Spruce, L. W., Birckbichler, P. J., Nelson, E. C., Subramanian, S., Weerasekare, G. M., Gale, J. B., Patterson M. K. Jr., Wang, B., Wang, W., Lu, S., Rowland, T. C., DiSivestro, P., Lindamood, C., III, Hill, D. L., and Berlin, K. D. Biologically active heteroarotinoids exhibiting anticancer activity and decreased toxicity. J. Med. Chem., 40: 3567-3583, 1997.
-
(1997)
J. Med. Chem.
, vol.40
, pp. 3567-3583
-
-
Benbrook, D.M.1
Madler, M.M.2
Spruce, L.W.3
Birckbichler, P.J.4
Nelson, E.C.5
Subramanian, S.6
Weerasekare, G.M.7
Gale, J.B.8
Patterson M.K., Jr.9
Wang, B.10
Wang, W.11
Lu, S.12
Rowland, T.C.13
DiSivestro, P.14
Lindamood C. III15
Hill, D.L.16
Berlin, K.D.17
-
20
-
-
0033539137
-
Synthesis, structure-activity relationships, and RARγ-ligand interactions of nitrogen heteroarotinoids
-
Dhar, A., Liu, S., Klucik, J., Berlin, K. D., Madler, M. M., Lu, S., Ivey, R. T., Zacheis, D., Brown, C. W., Nelson, E. C., Birckbichler, P. J., and Benbrook, D. M. Synthesis, structure-activity relationships, and RARγ-ligand interactions of nitrogen heteroarotinoids. J. Med. Chem., 42: 3602-3614, 1999.
-
(1999)
J. Med. Chem.
, vol.42
, pp. 3602-3614
-
-
Dhar, A.1
Liu, S.2
Klucik, J.3
Berlin, K.D.4
Madler, M.M.5
Lu, S.6
Ivey, R.T.7
Zacheis, D.8
Brown, C.W.9
Nelson, E.C.10
Birckbichler, P.J.11
Benbrook, D.M.12
-
21
-
-
0032718908
-
Heteroarotinoids inhibit head and neck cancer cell lines in vitro and in vivo through both RAR and RXR retinoic acid receptors
-
Zacheis, D., Dhar, A., Lu, S., Madler, M. M., Klucik, J., Brown, C. W., Liu, S., Clement, F., Subramanian, S., Weerasekare, G. M., Berlin, K. D., Gold, M. A., Houck, J. R., Jr., Fountain, K. R., and Benbrook, D. M. Heteroarotinoids inhibit head and neck cancer cell lines in vitro and in vivo through both RAR and RXR retinoic acid receptors. J. Med. Chem., 42: 4434-4445, 1999.
-
(1999)
J. Med. Chem.
, vol.42
, pp. 4434-4445
-
-
Zacheis, D.1
Dhar, A.2
Lu, S.3
Madler, M.M.4
Klucik, J.5
Brown, C.W.6
Liu, S.7
Clement, F.8
Subramanian, S.9
Weerasekare, G.M.10
Berlin, K.D.11
Gold, M.A.12
Houck J.R., Jr.13
Fountain, K.R.14
Benbrook, D.M.15
-
22
-
-
0035804648
-
Effects of retinoids on cancerous phenotype and apoptosis in organotypic cultures of ovarian carcinoma
-
Guruswamy, S., Lightfoot, S., Gold, M. A., Hassan, R., Berlin, K. D., Ivey, R. T., and Benbrook, D. M. Effects of retinoids on cancerous phenotype and apoptosis in organotypic cultures of ovarian carcinoma. J. Natl. Cancer Inst. (Bethesda), 93: 516-525, 2001.
-
(2001)
J. Natl. Cancer Inst. (Bethesda)
, vol.93
, pp. 516-525
-
-
Guruswamy, S.1
Lightfoot, S.2
Gold, M.A.3
Hassan, R.4
Berlin, K.D.5
Ivey, R.T.6
Benbrook, D.M.7
-
23
-
-
0029740183
-
Activation of specific RXR heterodimers by an antagonist of RXR homodimers
-
Lala, D. S., Mukherjee, R., Schulman, I. G., Koch, S. S., Dardashti, L. J., Nadzan, A. M., Croston, G. E., Evans, R. M., and Heyman, R. A. Activation of specific RXR heterodimers by an antagonist of RXR homodimers. Nature (Lond.), 383: 450-453, 1996.
-
(1996)
Nature (Lond.)
, vol.383
, pp. 450-453
-
-
Lala, D.S.1
Mukherjee, R.2
Schulman, I.G.3
Koch, S.S.4
Dardashti, L.J.5
Nadzan, A.M.6
Croston, G.E.7
Evans, R.M.8
Heyman, R.A.9
-
24
-
-
15844384344
-
AGN193109 is a highly effective antagonist of retinoid action in human ectocervical epithelial cells
-
Agarwal, C., Chandraratna, R. A., Johnson, A. T., Rorke, E. A., and Eckert, R. L. AGN193109 is a highly effective antagonist of retinoid action in human ectocervical epithelial cells. J. Biol. Chem., 271: 12209-12212, 1996.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 12209-12212
-
-
Agarwal, C.1
Chandraratna, R.A.2
Johnson, A.T.3
Rorke, E.A.4
Eckert, R.L.5
-
25
-
-
0030744057
-
Involvement of ROS in N-(4-hydroxyphenyl) retinamide-induced apoptosis in cervical carcinoma cells
-
Oridate, N., Suzuki, S., Higuchi, M., Mitchell, M. F., Hong, W. K., and Lotan, R. Involvement of ROS in N-(4-hydroxyphenyl) retinamide-induced apoptosis in cervical carcinoma cells. J. Natl. Cancer Inst. (Bethesda), 89: 1191-1198, 1997.
-
(1997)
J. Natl. Cancer Inst. (Bethesda)
, vol.89
, pp. 1191-1198
-
-
Oridate, N.1
Suzuki, S.2
Higuchi, M.3
Mitchell, M.F.4
Hong, W.K.5
Lotan, R.6
-
26
-
-
0032569838
-
Regulation of ROS-induced apoptosis and necrosis by caspase 3-like proteases
-
Higuchi, M., Honda, T., Proske, R. J., and Yeh, E. T. Regulation of ROS-induced apoptosis and necrosis by caspase 3-like proteases. Oncogene, 17: 2753-2760, 1998.
-
(1998)
Oncogene
, vol.17
, pp. 2753-2760
-
-
Higuchi, M.1
Honda, T.2
Proske, R.J.3
Yeh, E.T.4
-
27
-
-
0033523876
-
Implication of mitochondria-derived ROS, cytochrome c and caspase-3 in N-(4-hydroxyphenyl) retinamide-induced apoptosis in cervical carcinoma cells
-
Suzuki, S., Higuchi, M., Proske, R. J., Oridate, N., Hong, W. K., and Lotan, R. Implication of mitochondria-derived ROS, cytochrome c and caspase-3 in N-(4-hydroxyphenyl) retinamide-induced apoptosis in cervical carcinoma cells. Oncogene, 18: 6380-6387, 1999.
-
(1999)
Oncogene
, vol.18
, pp. 6380-6387
-
-
Suzuki, S.1
Higuchi, M.2
Proske, R.J.3
Oridate, N.4
Hong, W.K.5
Lotan, R.6
-
28
-
-
17144448793
-
The novel retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphtalene carboxylic acid can trigger apoptosis through a mitochondrial pathway independent of the nucleus
-
Marchetti, P., Zamzami, N., Joseph, B., Schraen-Maschke, S., Mereau-Richard, C., Costantini, P., Metivier, D., Susin, S. A., Kroemer, G., and Formstecher, P. The novel retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphtalene carboxylic acid can trigger apoptosis through a mitochondrial pathway independent of the nucleus. Cancer Res., 59: 6257-6266, 1999.
-
(1999)
Cancer Res.
, vol.59
, pp. 6257-6266
-
-
Marchetti, P.1
Zamzami, N.2
Joseph, B.3
Schraen-Maschke, S.4
Mereau-Richard, C.5
Costantini, P.6
Metivier, D.7
Susin, S.A.8
Kroemer, G.9
Formstecher, P.10
-
29
-
-
0030729437
-
Trifluoperazine and dibucaine-induced inhibition of glutamate-induced mitochondrial depolarization in rat cultured forebrain neurones
-
Hoyt, K. R., Sharma, T. A., and Reynolds, I. J. Trifluoperazine and dibucaine-induced inhibition of glutamate-induced mitochondrial depolarization in rat cultured forebrain neurones. Br. J. Pharmacol., 122: 803-808, 1997.
-
(1997)
Br. J. Pharmacol.
, vol.122
, pp. 803-808
-
-
Hoyt, K.R.1
Sharma, T.A.2
Reynolds, I.J.3
-
30
-
-
12944332005
-
Phase I trial of all-trans-retinoic acid in patients with treated head and neck squamous carcinoma
-
Park, S. H., Gray, W. C., Hernandez, I., Jacobs, M., Ord, R. A., Sutharalingam, M., Smith, R. G., Van Echo, D. A., Wu, S., and Conley, B. A. Phase I trial of all-trans-retinoic acid in patients with treated head and neck squamous carcinoma. Clin. Cancer Res., 6: 847-854, 2000.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 847-854
-
-
Park, S.H.1
Gray, W.C.2
Hernandez, I.3
Jacobs, M.4
Ord, R.A.5
Sutharalingam, M.6
Smith, R.G.7
Van Echo, D.A.8
Wu, S.9
Conley, B.A.10
-
31
-
-
0034084925
-
Initial clinical trial of a high-affinity retinoic acid receptor ligand (LGD1550)
-
Soignet, S. L., Miller, V. A., Pfister, D. G., Bienvenu, B. J., Ho, R., Parker, B. A., Amyotte, S. A., Cato, A., III, and Warrell, R. P., Jr. Initial clinical trial of a high-affinity retinoic acid receptor ligand (LGD1550). Clin. Cancer Res., 6: 1731-1735, 2000.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 1731-1735
-
-
Soignet, S.L.1
Miller, V.A.2
Pfister, D.G.3
Bienvenu, B.J.4
Ho, R.5
Parker, B.A.6
Amyotte, S.A.7
Cato A. III8
Warrell R.P., Jr.9
-
32
-
-
0035146629
-
Experience with 9-cis retinoic acid in patients with relapsed and refractory non-Hodgkin's lymphoma
-
Younes, A., Cristofanilli, M., McLaughlin, P., Hagemeister, F. B., Weber, D., Mesina, O., and Cabanillas, F. Experience with 9-cis retinoic acid in patients with relapsed and refractory non-Hodgkin's lymphoma. Leuk. Lymphoma, 40: 79-85, 2000.
-
(2000)
Leuk. Lymphoma
, vol.40
, pp. 79-85
-
-
Younes, A.1
Cristofanilli, M.2
McLaughlin, P.3
Hagemeister, F.B.4
Weber, D.5
Mesina, O.6
Cabanillas, F.7
-
33
-
-
0025979704
-
Novel heteroarotinoids: Synthesis and biological activity
-
Spruce, L. W., Gale, J. B., Berlin, K. D., Verma, A. K., Breitman, T. R., Ji, X. H., and van der Helm, D. Novel heteroarotinoids: synthesis and biological activity. J. Med. Chem., 34: 430-439, 1991.
-
(1991)
J. Med. Chem.
, vol.34
, pp. 430-439
-
-
Spruce, L.W.1
Gale, J.B.2
Berlin, K.D.3
Verma, A.K.4
Breitman, T.R.5
Ji, X.H.6
Van der Helm, D.7
-
34
-
-
0032505176
-
Synthesis and characterization of heteroarotinoids demonstrate structure specificity relationships
-
Benbrook, D. M., Subramanian, S., Gale, J. B., Liu, S., Brown, C. W., Boehm, M. F., and Berlin, K. D. Synthesis and characterization of heteroarotinoids demonstrate structure specificity relationships. J. Med. Chem., 41: 3753-3757, 1998.
-
(1998)
J. Med. Chem.
, vol.41
, pp. 3753-3757
-
-
Benbrook, D.M.1
Subramanian, S.2
Gale, J.B.3
Liu, S.4
Brown, C.W.5
Boehm, M.F.6
Berlin, K.D.7
-
35
-
-
0035811450
-
Heterocycle-containing retinoids. Discovery of a novel isoxazole arotinoid possessing potent apoptotic activity in multidrug and drug-induced apoptosis-resistant cells
-
Simoni, D., Roberti, M., Invidiata, F. P., Rondanin, R., Baruchello, R., Malagutti, C., Mazzali, A., Rossi, M., Grimaudo, S., Capon, F., Dusonchet, L., Meli, M., Raimondi, M. V., Landino, M., D'Alessandro, N., Tolomeo, M., Arindam, D., Lu, S., and Benbrook, D. M. Heterocycle-containing retinoids. Discovery of a novel isoxazole arotinoid possessing potent apoptotic activity in multidrug and drug-induced apoptosis-resistant cells. J. Med. Chem., 44: 2308-2318, 2001.
-
(2001)
J. Med. Chem.
, vol.44
, pp. 2308-2318
-
-
Simoni, D.1
Roberti, M.2
Invidiata, F.P.3
Rondanin, R.4
Baruchello, R.5
Malagutti, C.6
Mazzali, A.7
Rossi, M.8
Grimaudo, S.9
Capon, F.10
Dusonchet, L.11
Meli, M.12
Raimondi, M.V.13
Landino, M.14
D'Alessandro, N.15
Tolomeo, M.16
Arindam, D.17
Lu, S.18
Benbrook, D.M.19
-
36
-
-
0028787351
-
Retinoids and apoptosis: Implications for cancer chemoprevention and therapy
-
Lotan, R. Retinoids and apoptosis: implications for cancer chemoprevention and therapy. J. Natl. Cancer Inst. (Bethesda), 87: 1655-1657, 1995.
-
(1995)
J. Natl. Cancer Inst. (Bethesda)
, vol.87
, pp. 1655-1657
-
-
Lotan, R.1
-
37
-
-
0027332981
-
N-(4-Hydroxyphenyl)retinamide induces apoptosis of malignant hemopoietic cell lines including those unresponsive to retinoic acid
-
Delia, D., Aiello, A., Lombardi, L., Pelicci, P. G., Grignani, F., Grignani, F., Formelli, F., Menard, S., Costa, A., and Veronesi, U. N-(4-Hydroxyphenyl)retinamide induces apoptosis of malignant hemopoietic cell lines including those unresponsive to retinoic acid. Cancer Res., 53: 6036-6041, 1993.
-
(1993)
Cancer Res.
, vol.53
, pp. 6036-6041
-
-
Delia, D.1
Aiello, A.2
Lombardi, L.3
Pelicci, P.G.4
Grignani, F.5
Grignani, F.6
Formelli, F.7
Menard, S.8
Costa, A.9
Veronesi, U.10
-
38
-
-
0036765969
-
Synthetic retinoid CD437 induces cell-dependent cycle arrest by differential regulation of cell cycle associated proteins
-
Shyu, R. Y., Lin, D. Y., Reichert, U., and Jiang, S. Y. Synthetic retinoid CD437 induces cell-dependent cycle arrest by differential regulation of cell cycle associated proteins. Anticancer Res., 22: 2757-2764, 2002.
-
(2002)
Anticancer Res.
, vol.22
, pp. 2757-2764
-
-
Shyu, R.Y.1
Lin, D.Y.2
Reichert, U.3
Jiang, S.Y.4
-
39
-
-
0036870187
-
Head and neck squamous cell carcinoma is highly sensitive to vinorelbine in vitro
-
Erjala, K., Pulkkinen, J., Kulmala, J., Alanen, K., and Grenman, R. Head and neck squamous cell carcinoma is highly sensitive to vinorelbine in vitro. Anticancer Res., 22: 3135-3142, 2002.
-
(2002)
Anticancer Res.
, vol.22
, pp. 3135-3142
-
-
Erjala, K.1
Pulkkinen, J.2
Kulmala, J.3
Alanen, K.4
Grenman, R.5
-
40
-
-
0037772194
-
2-M cell cycle arrest, activation of caspase 8 or caspase 9 and synergy with APO2/TRAIL
-
2-M cell cycle arrest, activation of caspase 8 or caspase 9 and synergy with APO2/TRAIL. Blood, 101: 4078-4087, 2003.
-
(2003)
Blood
, vol.101
, pp. 4078-4087
-
-
Liu, Q.1
Hilsenbeck, S.2
Gazitt, Y.3
-
41
-
-
0035824633
-
Mitochondrial respiration is uniquely associated with the prooxidant and apoptotic effects of N-(4-hydroxyphenyl)retinamide
-
Hail, N., Jr., and Lotan, R. Mitochondrial respiration is uniquely associated with the prooxidant and apoptotic effects of N-(4-hydroxyphenyl)retinamide. J. Biol. Chem., 276: 45614-45621, 2001.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 45614-45621
-
-
Hail N., Jr.1
Lotan, R.2
-
42
-
-
0028894557
-
Low levels of ROS as modulators of cell function
-
Remacle, J., Raes, M., Toussaint, O., Renard, P., and Rao, G. Low levels of ROS as modulators of cell function. Mutat. Res., 316: 103-122, 1995.
-
(1995)
Mutat. Res.
, vol.316
, pp. 103-122
-
-
Remacle, J.1
Raes, M.2
Toussaint, O.3
Renard, P.4
Rao, G.5
-
43
-
-
0028176651
-
Oxidative stress as a mediator of apoptosis
-
Buttke, T. M., and Sandstrom, P. A. Oxidative stress as a mediator of apoptosis. Immunol. Today, 15: 7-10, 1994.
-
(1994)
Immunol. Today
, vol.15
, pp. 7-10
-
-
Buttke, T.M.1
Sandstrom, P.A.2
-
44
-
-
0027269781
-
H2O2 and antioxidants have opposite effects on activation of NF-κB and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor
-
Meyer, M., Schreck, R., and Baeuerle, P. A. H2O2 and antioxidants have opposite effects on activation of NF-κB and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor. EMBO J., 12: 2005-2015, 1993.
-
(1993)
EMBO J.
, vol.12
, pp. 2005-2015
-
-
Meyer, M.1
Schreck, R.2
Baeuerle, P.A.3
-
45
-
-
0027328056
-
Depletion of the mitochondrial electron transport abrogates the cytotoxic and gene-inductive effects of TNF
-
Schulze-Osthoff, K., Beyaert, R., Vandevoorde, V., Haegeman, G., and Fiers, W. Depletion of the mitochondrial electron transport abrogates the cytotoxic and gene-inductive effects of TNF. EMBO J., 12: 3095-30104, 1993.
-
(1993)
EMBO J.
, vol.12
, pp. 3095-30104
-
-
Schulze-Osthoff, K.1
Beyaert, R.2
Vandevoorde, V.3
Haegeman, G.4
Fiers, W.5
-
46
-
-
0028015832
-
Production of hydrogen peroxide by transforming growth factor-β1 and its involvement in induction of egr-1 in mouse osteoblastic cells
-
Ohba, M., Shibanuma, M., Kuroki, T., and Nose, K. Production of hydrogen peroxide by transforming growth factor-β1 and its involvement in induction of egr-1 in mouse osteoblastic cells. J. Cell. Biol., 126: 1079-1088, 1994.
-
(1994)
J. Cell. Biol.
, vol.126
, pp. 1079-1088
-
-
Ohba, M.1
Shibanuma, M.2
Kuroki, T.3
Nose, K.4
-
47
-
-
0031034997
-
Interaction of CED-4 with CED-3 and CED-9: A molecular framework for cell death
-
Chinnaiyan, A. M., O'Rourke, K., Lane, B. R., and Dixit, V. M. Interaction of CED-4 with CED-3 and CED-9: a molecular framework for cell death. Science (Wash. DC), 275: 1122-1126, 1997.
-
(1997)
Science (Wash. DC)
, vol.275
, pp. 1122-1126
-
-
Chinnaiyan, A.M.1
O'Rourke, K.2
Lane, B.R.3
Dixit, V.M.4
-
48
-
-
0026696585
-
Purification and N-terminal sequencing of peptidyl-prolyl cis-trans-isomerase from rat liver mitochondrial matrix reveals the existence of a distinct mitochondrial cyclophilin
-
Connern, C. P., and Halestrap, A. P. Purification and N-terminal sequencing of peptidyl-prolyl cis-trans-isomerase from rat liver mitochondrial matrix reveals the existence of a distinct mitochondrial cyclophilin. Biochem. J., 284: 381-385, 1992.
-
(1992)
Biochem. J.
, vol.284
, pp. 381-385
-
-
Connern, C.P.1
Halestrap, A.P.2
-
49
-
-
0033565557
-
The mitochondrial permeability transition pore and its role in cell death
-
Crompton, M. The mitochondrial permeability transition pore and its role in cell death. Biochem. J., 341: 233-249, 1999.
-
(1999)
Biochem. J.
, vol.341
, pp. 233-249
-
-
Crompton, M.1
-
50
-
-
0036478989
-
The permeability transition pore complex: Another view
-
Halestrap, A. P., McStay, G. P., and Clarke, S. J. The permeability transition pore complex: another view. Biochimie, 84: 153-166, 2002.
-
(2002)
Biochimie
, vol.84
, pp. 153-166
-
-
Halestrap, A.P.1
McStay, G.P.2
Clarke, S.J.3
-
51
-
-
0032575752
-
Mitochondria and apoptosis
-
Green, D. R., and Reed, J. C. Mitochondria and apoptosis. Science (Wash. DC), 281: 1309-1312, 1998.
-
(1998)
Science (Wash. DC)
, vol.281
, pp. 1309-1312
-
-
Green, D.R.1
Reed, J.C.2
-
52
-
-
0030715323
-
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
-
Li, P., Nijhawan, D., Budihardjo, I., Srinivasula, S. M., Ahmad, M., Alnemri, E. S., and Wang, X. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell, 91: 479-489, 1997.
-
(1997)
Cell
, vol.91
, pp. 479-489
-
-
Li, P.1
Nijhawan, D.2
Budihardjo, I.3
Srinivasula, S.M.4
Ahmad, M.5
Alnemri, E.S.6
Wang, X.7
-
53
-
-
0030745646
-
Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3
-
Zou, H., Henzel, W. J., Liu, X., Lutschg, A., and Wang, X. Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell, 90: 405-413, 1997.
-
(1997)
Cell
, vol.90
, pp. 405-413
-
-
Zou, H.1
Henzel, W.J.2
Liu, X.3
Lutschg, A.4
Wang, X.5
-
54
-
-
0030821826
-
Role of CED-4 in the activation of CED-3
-
Chinnaiyan, A. M., Chaudhary, D., O'Rourke, K., Koonin, E. V., and Dixit, V. M. Role of CED-4 in the activation of CED-3. Nature (Lond.), 388: 728-729, 1997.
-
(1997)
Nature (Lond.)
, vol.388
, pp. 728-729
-
-
Chinnaiyan, A.M.1
Chaudhary, D.2
O'Rourke, K.3
Koonin, E.V.4
Dixit, V.M.5
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