Synthesis, structure-activity relationships, and RARγ-ligand interactions of nitrogen heteroarotinoids

Journal of Medicinal Chemistry

Volumn 42, Issue 18, 1999, Pages 3602-3614

  Dhar, Arindam ^a   Liu, Shengquan ^b   Klucik, Jozef ^b   Berlin, K Darrell ^b   Madler, Matora M ^b   Lu, Shennan ^a   Ivey, R Todd ^a   Zacheis, David ^c   Brown, Chad W ^b   Nelson, E C ^b   Birckbichler, Paul J ^a   Benbrook, Doris M ^a  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^b OKLAHOMA STATE UNIVERSITY   (United States)

^c UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (N,4,4,7 TETRAMETHYL 1,2,3,4 TETRAHYDROQUINOLIN 6 OYLOXY)BENZOIC ACID ETHYL ESTER; AROTINOID; HETEROAROTINOID; RETINOIC ACID RECEPTOR; RETINOID; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CANCER INHIBITION; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SPECIFICITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INDUCTION; HUMAN; HUMAN CELL; HYDROPHOBICITY; LIGAND BINDING; MOLECULAR MODEL; STRUCTURE ACTIVITY RELATION; TRANSACTIVATION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL DIVISION; HUMANS; LIGANDS; MODELS, MOLECULAR; QUINOLINES; RECEPTORS, RETINOIC ACID; RETINOID X RECEPTORS; RETINOIDS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; TRANSGLUTAMINASES; TUMOR CELLS, CULTURED;

EID: 0033539137     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9900974     Document Type: Article

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