Biologically active heteroarotinoids exhibiting anticancer activity and decreased toxicity

Journal of Medicinal Chemistry

Volumn 40, Issue 22, 1997, Pages 3567-3583

  Benbrook, Doris M ^a   Madler, Matora M ^b   Spruce, Lyle W ^b   Birckbichler, Paul J ^a   Nelson, Eldon C ^b   Subramanian, Shankar ^b   Mahika Weerasekare, G ^b   Gale, Jonathan B ^b   Patterson Jr , Manford K ^c   Wang, Binghe ^d   Wang, Wei ^d   Lu, Shennan ^a   Rowland, Tami C ^a   DiSivestro, Paul ^a   Lindamood III, Charles ^e   Hill, Donald L ^e   Berlin, K Darrell ^b  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^b OKLAHOMA STATE UNIVERSITY   (United States)

^c PLANT BIOLOGY DIVISION   (United States)

^d UNIVERSITY OF OKLAHOMA   (United States)

^e SOUTHERN RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3,7 DIMETHYL 7 (1,2,3,4 TETRAHYDRO 4,4 DIMETHYL 6 THIOCHROMANYL) 2,4,6 HEPTATRIENOIC ACID; 3,7 DIMETHYL 7 (1,2,3,4 TETRAHYDRO 4,4 DIMETHYLCHROMAN 6 YL) 2,4,6 HEPTATRIENOIC ACID; 4 [2 (4,4 DIMETHYLCHROMAN 6 YL)PROPENYL]BENZOIC ACID; ANTINEOPLASTIC AGENT; AROTINOID; RETINOIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG TOLERABILITY; ERYTHROLEUKEMIA CELL; HUMAN; HUMAN CELL; MALE; MALIGNANT NEOPLASTIC DISEASE; MOUSE; NONHUMAN; TOXICITY TESTING;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL DIVISION; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MASS SPECTROMETRY; MICE; MOLECULAR STRUCTURE; RETINOIDS; TUMOR CELLS, CULTURED;

EID: 9844266252     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970196m     Document Type: Article

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