Cellular mechanisms for human procollagenase-3 (MMP-13) activation. Evidence that MT1-MMP (MMP-14) and gelatinase A (MMP-2) are able to generate active enzyme

Journal of Biological Chemistry

Volumn 271, Issue 29, 1996, Pages 17124-17131

  Knäuper, Vera ^a   Will, Horst ^b   López Otin, Carlos ^c   Smith, Bryan ^d   Atkinson, Susan J ^a   Stanton, Heather ^a   Hembry, Rosalind M ^a   Murphy, Gillian ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b InViTek GmbH   (Germany)

^c DEPARTAMENTO DE BIOQUÍMICA Y BIOLOGÍA MOLECULAR   (Spain)

^d UCB PHARMA   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

APROTININ; CONCANAVALIN A; GELATINASE; METALLOPROTEINASE; PLASMIN; PLASMINOGEN ACTIVATOR INHIBITOR 2; POLYCLONAL ANTIBODY; PROCOLLAGENASE; RECOMBINANT PROTEIN; TISSUE INHIBITOR OF METALLOPROTEINASE;

AMINO TERMINAL SEQUENCE; ARTICLE; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ASSAY; ENZYME INHIBITION; ENZYME PURIFICATION; FIBROBLAST CULTURE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PROCESSING;

AMINO ACID SEQUENCE; APROTININ; BASE SEQUENCE; CLONING, MOLECULAR; COLLAGENASES; DNA PRIMERS; ENZYME ACTIVATION; ESCHERICHIA COLI; GELATINASES; HUMANS; KINETICS; MATRIX METALLOPROTEINASE 13; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASES, MEMBRANE-ASSOCIATED; METALLOENDOPEPTIDASES; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; MUTAGENESIS, SITE-DIRECTED; PLASMIN; POINT MUTATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECOMBINANT PROTEINS; TYROSINE;

EID: 0030037395     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.29.17124     Document Type: Article

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