A natural ErbB4 isoform that does not activate phosphoinositide 3-kinase mediates proliferation but not survival or chemotaxis

Journal of Biological Chemistry

Volumn 275, Issue 12, 2000, Pages 8641-8649

  Kainulainen, Varpu ^a,b   Sundvall, Maria ^a,b   Määttä, Jorma A ^a   Santiestevan, Eric ^c   Klagsbrun, Michael ^c   Elenius, Klaus ^a,b  

^a UNIVERSITY OF TURKU   (Finland)

^b UNIVERSITY OF TURKU   (Finland)

^c BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4',6 DIAMIDINO 2 PHENYLINDOLE; EPIDERMAL GROWTH FACTOR RECEPTOR; GROWTH FACTOR; NEU DIFFERENTIATION FACTOR; PHOSPHATIDYLINOSITOL 3 KINASE;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL PROLIFERATION; CELL SURVIVAL; CHEMOTAXIS; CONTROLLED STUDY; ENZYME ACTIVATION; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; PRIORITY JOURNAL;

1-PHOSPHATIDYLINOSITOL 3-KINASE; 3T3 CELLS; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; APOPTOSIS; CELL DIVISION; CELL SURVIVAL; CHEMOTAXIS; CULTURE MEDIA, SERUM-FREE; ENZYME ACTIVATION; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; NEUREGULIN-1; PHOSPHORYLATION; PROTEIN ISOFORMS; PROTEIN-SERINE-THREONINE KINASES; PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0034708598     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.12.8641     Document Type: Article

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