Antisense protein tyrosine phosphatase 1B reverses activation of p38 mitogen-activated protein kinase in liver of ob/ob mice

Molecular Endocrinology

Volumn 17, Issue 6, 2003, Pages 1131-1143

  Gum, Rebecca J ^a   Gaede, Lori L ^a   Heindel, Matthew A ^a   Waring, Jeffrey F ^a   Trevillyan, James M ^a   Zinker, Bradley A ^a   Stark, Margery E ^a   Wilcox, Denise ^a   Jirousek, Michael R ^a,b   Rondinone, Cristina M ^a   Ulrich, Roger G ^a,c  

^a ABBOTT LABORATORIES   (United States)

^b PFIZER INC   (United States)

^c ROSETTA INPHARMATICS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; GLUCOSE; INSULIN; INSULIN RECEPTOR; ISIS 113715; LIVER ENZYME; LIVER PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE; ROSIGLITAZONE; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; CORRELATION ANALYSIS; DIABETES MELLITUS; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ANALYSIS; ENZYME PHOSPHORYLATION; ENZYME SUBSTRATE; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; LIVER; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

ANIMALS; BLOOD GLUCOSE; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DIABETES MELLITUS; INSULIN; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIVER; MICE; MICE, INBRED C57BL; MITOGEN-ACTIVATED PROTEIN KINASES; OBESITY; OLIGONUCLEOTIDES, ANTISENSE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN-TYROSINE-PHOSPHATASE; RANDOM ALLOCATION; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA;

EID: 0038517834     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2002-0288     Document Type: Article

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