Synchrotron photoactivation of cisplatin elicits an extra number of DNA breaks that stimulate RAD51-mediated repair pathways

Cancer Research

Volumn 63, Issue 12, 2003, Pages 3221-3227

  Corde, Stéphanie ^a   Balosso, Jacques ^a   Elleaume, Hélène ^a   Renier, Michel ^b   Joubert, Aurélie ^a   Biston, Marie Claude ^a   Adam, Jean François ^a   Charvet, Anne Marie ^a   Brochard, Thierry ^b   Le Bas, Jean François ^a   Estève, François ^a   Foray, Nicolas ^a,c  

^a HÔPITAL MICHALLON   (France)

^b EUROPEAN SYNCHROTRON RADIATION FACILITY   (France)

^c UNIVERSITY OF SUSSEX   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; CISPLATIN; CYSPLATYL; DNA; DNA PROTEIN KINASE; ONCOPROTEIN; ONCOPROTEIN TYROSINE KINASE; PROTEIN KINASE; PROTEIN TYROSINE KINASE; RAD51 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; DNA REPAIR; DNA STRAND BREAKAGE; DRUG ACTIVATION; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; INTRACELLULAR TRANSPORT; IONIZING RADIATION; ONCOGENE; PHOTOACTIVATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; SYNCHROTRON;

ACTIVE TRANSPORT, CELL NUCLEUS; BRCA1 PROTEIN; BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; CARCINOMA, SQUAMOUS CELL; CISPLATIN; DNA ADDUCTS; DNA DAMAGE; DNA REPAIR; DNA-ACTIVATED PROTEIN KINASE; DNA-BINDING PROTEINS; ELECTRONS; ELECTROPHORESIS, GEL, PULSED-FIELD; ENZYME ACTIVATION; FEASIBILITY STUDIES; FEMALE; GENE DELETION; GENES, BRCA1; HEAD AND NECK NEOPLASMS; HUMANS; MODELS, BIOLOGICAL; MUTAGENESIS, INSERTIONAL; NEOPLASM PROTEINS; NUCLEAR PROTEINS; PHOTOCHEMISTRY; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-ABL; RAD51 RECOMBINASE; SYNCHROTRONS;

EID: 0038407516     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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