-
1
-
-
0029741063
-
The future of genetic studies of complex human diseases
-
Risch N., Merikangas K. The future of genetic studies of complex human diseases. Science. 273:1996;1516-1517.
-
(1996)
Science
, vol.273
, pp. 1516-1517
-
-
Risch, N.1
Merikangas, K.2
-
2
-
-
0026949420
-
Linkage disequilibrium mapping in isolated founder populations: Diastrophic dysplasia in Finland
-
Hastbäcka J., de la Chapelle A., Kaitila I., Sistonen P., Weaver A., Lander E. Linkage disequilibrium mapping in isolated founder populations: diastrophic dysplasia in Finland. Nat. Genet. 2:1992;204-211.
-
(1992)
Nat. Genet.
, vol.2
, pp. 204-211
-
-
Hastbäcka, J.1
De la Chapelle, A.2
Kaitila, I.3
Sistonen, P.4
Weaver, A.5
Lander, E.6
-
3
-
-
0028298036
-
Maximum-likelihood estimation of gene location by linkage disequilibrium
-
Hill W.G., Weir B.S. Maximum-likelihood estimation of gene location by linkage disequilibrium. Am. J. Hum. Genet. 54:1994;705-714.
-
(1994)
Am. J. Hum. Genet.
, vol.54
, pp. 705-714
-
-
Hill, W.G.1
Weir, B.S.2
-
4
-
-
0032231888
-
Haplotype structure and population genetic inferences from nucleotide-sequence variation in human lipoprotein lipase
-
Clark A.G., Weiss K.M., Nickerson D.A., Taylor S.L., Buchanan A., Stengård J., Salomaa V., Vartiainen E., Perola M., Boerwinkle E., Sing C.F. Haplotype structure and population genetic inferences from nucleotide-sequence variation in human lipoprotein lipase. Am. J. Hum. Genet. 63:1998;595-612.
-
(1998)
Am. J. Hum. Genet.
, vol.63
, pp. 595-612
-
-
Clark, A.G.1
Weiss, K.M.2
Nickerson, D.A.3
Taylor, S.L.4
Buchanan, A.5
Stengård, J.6
Salomaa, V.7
Vartiainen, E.8
Perola, M.9
Boerwinkle, E.10
Sing, C.F.11
-
5
-
-
0036208832
-
Patterns of linkage disequilibrium in the human genome
-
Ardlie K.G., Kruglyak L., Seielstad M. Patterns of linkage disequilibrium in the human genome. Nat. Rev. Genet. 3:2002;299-309.
-
(2002)
Nat. Rev. Genet.
, vol.3
, pp. 299-309
-
-
Ardlie, K.G.1
Kruglyak, L.2
Seielstad, M.3
-
6
-
-
0033799573
-
Apolipoprotein E variation at the sequence haplotype level: Implications for the origin and maintenance of a major human polymorphism
-
Fullerton S.M., Clark A.G., Weiss K.M., Nickerson D.A., Taylor S.L., Stengård J.H., Salomaa V., Vartiainen E., Perola M., Boerwinkle E., Sing C.F. Apolipoprotein E variation at the sequence haplotype level: implications for the origin and maintenance of a major human polymorphism. Am. J. Hum. Genet. 67:2000;881-900.
-
(2000)
Am. J. Hum. Genet.
, vol.67
, pp. 881-900
-
-
Fullerton, S.M.1
Clark, A.G.2
Weiss, K.M.3
Nickerson, D.A.4
Taylor, S.L.5
Stengård, J.H.6
Salomaa, V.7
Vartiainen, E.8
Perola, M.9
Boerwinkle, E.10
Sing, C.F.11
-
7
-
-
17344364213
-
DNA sequence diversity in a 9.7-kb region of the human lipoprotein lipase gene
-
Nickerson D.A., Taylor S.L., Weiss K.M., Clark A.G., Hutchinson R.G., Stengård J., Salomaa V., Vartiainen E., Boerwinkle E., Sing C.F. DNA sequence diversity in a 9.7-kb region of the human lipoprotein lipase gene. Nat. Genet. 19:1998;233-240.
-
(1998)
Nat. Genet.
, vol.19
, pp. 233-240
-
-
Nickerson, D.A.1
Taylor, S.L.2
Weiss, K.M.3
Clark, A.G.4
Hutchinson, R.G.5
Stengård, J.6
Salomaa, V.7
Vartiainen, E.8
Boerwinkle, E.9
Sing, C.F.10
-
8
-
-
0029150074
-
A comparison of linkage disequilibrium measures for fine-scale mapping
-
Devlin B., Risch N. A comparison of linkage disequilibrium measures for fine-scale mapping. Genomics. 29:1995;311-322.
-
(1995)
Genomics
, vol.29
, pp. 311-322
-
-
Devlin, B.1
Risch, N.2
-
9
-
-
0035837267
-
Linkage disequilibrium in the human genome
-
This paper took a broader look at LD in the human genome by selecting 19 sets of SNPs spanning windows of ∼160 kb, and showed clearly that different regions had dramatically different rates of LD decay, and that different populations also had different rates of LD decay.
-
Reich D.E., Cargill M., Bolk S., Ireland J., Sabeti P.C., Richter D.J., Lavery T., Kouyoumjian R., Farhadian S.F., Ward R., Lander E.S. Linkage disequilibrium in the human genome. Nature. 411:2001;199-204 This paper took a broader look at LD in the human genome by selecting 19 sets of SNPs spanning windows of ∼160 kb, and showed clearly that different regions had dramatically different rates of LD decay, and that different populations also had different rates of LD decay.
-
(2001)
Nature
, vol.411
, pp. 199-204
-
-
Reich, D.E.1
Cargill, M.2
Bolk, S.3
Ireland, J.4
Sabeti, P.C.5
Richter, D.J.6
Lavery, T.7
Kouyoumjian, R.8
Farhadian, S.F.9
Ward, R.10
Lander, E.S.11
-
10
-
-
18444369013
-
The structure of haplotype blocks in the human genome
-
Gabriel S.B., Schaffner S.F., Nguyen H., Moore J.M., Roy J., Blumenstiel B., Higgins J., DeFelice M., Lochner A., Faggart M.et al. The structure of haplotype blocks in the human genome. Science. 296:2002;2225-2229.
-
(2002)
Science
, vol.296
, pp. 2225-2229
-
-
Gabriel, S.B.1
Schaffner, S.F.2
Nguyen, H.3
Moore, J.M.4
Roy, J.5
Blumenstiel, B.6
Higgins, J.7
DeFelice, M.8
Lochner, A.9
Faggart, M.10
-
11
-
-
18444396271
-
A first-generation linkage disequilibrium map of human chromosome 22
-
Dawson E., Abecasis G.R., Bumpstead S., Chen Y., Hunt S., Beare D.M., Pabial J., Dibling T., Tinsley E., Kirby S.et al. A first-generation linkage disequilibrium map of human chromosome 22. Nature. 418:2002;544-548.
-
(2002)
Nature
, vol.418
, pp. 544-548
-
-
Dawson, E.1
Abecasis, G.R.2
Bumpstead, S.3
Chen, Y.4
Hunt, S.5
Beare, D.M.6
Pabial, J.7
Dibling, T.8
Tinsley, E.9
Kirby, S.10
-
13
-
-
0036226789
-
Patterns of human diversity, within and among continents, inferred from biallelic DNA polymorphisms
-
Romualdi C., Balding D., Nasidze I.S., Risch G., Robichaux M., Sherry S.T., Stoneking M., Batzer M.A., Barbujani G. Patterns of human diversity, within and among continents, inferred from biallelic DNA polymorphisms. Genome Res. 12:2002;602-612.
-
(2002)
Genome Res.
, vol.12
, pp. 602-612
-
-
Romualdi, C.1
Balding, D.2
Nasidze, I.S.3
Risch, G.4
Robichaux, M.5
Sherry, S.T.6
Stoneking, M.7
Batzer, M.A.8
Barbujani, G.9
-
14
-
-
0033786787
-
Linkage disequilibrium and the search for complex disease genes
-
Jorde L.B. Linkage disequilibrium and the search for complex disease genes. Genome Res. 10:2000;1435-1444.
-
(2000)
Genome Res.
, vol.10
, pp. 1435-1444
-
-
Jorde, L.B.1
-
15
-
-
0035528928
-
Case-control studies of association in structured or admixed populations
-
Pritchard J.K., Donnelly P. Case-control studies of association in structured or admixed populations. Theor. Popul. Biol. 60:2001;227-237.
-
(2001)
Theor. Popul. Biol.
, vol.60
, pp. 227-237
-
-
Pritchard, J.K.1
Donnelly, P.2
-
16
-
-
0033941841
-
Haplotypes and linkage disequilibrium at the phenylalanine hydroxylase locus, PAH, in a global representation of populations
-
Kidd J.R., Pakstis A.J., Zhao H., Lu R.B., Okonofua F.E., Odunsi A., Grigorenko E., Tamir B.B., Friedlaender J., Schulz L.O.et al. Haplotypes and linkage disequilibrium at the phenylalanine hydroxylase locus, PAH, in a global representation of populations. Am. J. Hum. Genet. 66:2000;1882-1899.
-
(2000)
Am. J. Hum. Genet.
, vol.66
, pp. 1882-1899
-
-
Kidd, J.R.1
Pakstis, A.J.2
Zhao, H.3
Lu, R.B.4
Okonofua, F.E.5
Odunsi, A.6
Grigorenko, E.7
Tamir, B.B.8
Friedlaender, J.9
Schulz, L.O.10
-
17
-
-
0037422542
-
Sequence variations in the public human genome data reflect a bottlenecked population history
-
Marth G., Schuler G., Yeh R., Davenport R., Agarwala R., Church D., Wheelan S., Baker J., Ward M., Kholodov M.et al. Sequence variations in the public human genome data reflect a bottlenecked population history. Proc. Natl. Acad Sci. USA. 100:2003;376-381.
-
(2003)
Proc. Natl. Acad Sci. USA
, vol.100
, pp. 376-381
-
-
Marth, G.1
Schuler, G.2
Yeh, R.3
Davenport, R.4
Agarwala, R.5
Church, D.6
Wheelan, S.7
Baker, J.8
Ward, M.9
Kholodov, M.10
-
18
-
-
0034977045
-
Linkage disequilibrium in humans: Models and data
-
An assessment of the implications of observations of human LD and how well the observations correspond to theoretical population genetic predictions.
-
Pritchard J.K., Przeworski M. Linkage disequilibrium in humans: models and data. Am. J. Hum. Genet. 69:2001;1-14 An assessment of the implications of observations of human LD and how well the observations correspond to theoretical population genetic predictions.
-
(2001)
Am. J. Hum. Genet.
, vol.69
, pp. 1-14
-
-
Pritchard, J.K.1
Przeworski, M.2
-
19
-
-
0036245475
-
Understanding quantitative genetic variation
-
Barton N.H., Keightley P. Understanding quantitative genetic variation. Nat. Rev. Genet. 3:2002;11-21.
-
(2002)
Nat. Rev. Genet.
, vol.3
, pp. 11-21
-
-
Barton, N.H.1
Keightley, P.2
-
20
-
-
0034660559
-
Searching for genetic determinants in the new millenium
-
Risch N.J. Searching for genetic determinants in the new millenium. Nature. 405:2000;847-856.
-
(2000)
Nature
, vol.405
, pp. 847-856
-
-
Risch, N.J.1
-
21
-
-
0037177589
-
Maneuvering in the complex path from genotype to phenotype
-
Strohman R. Maneuvering in the complex path from genotype to phenotype. Science. 296:2002;701-703.
-
(2002)
Science
, vol.296
, pp. 701-703
-
-
Strohman, R.1
-
22
-
-
0033780104
-
How many diseases does it take to map a gene with SNPs?
-
Weiss K.M., Terwilliger J.D. How many diseases does it take to map a gene with SNPs? Nat. Genet. 26:2000;151-157.
-
(2000)
Nat. Genet.
, vol.26
, pp. 151-157
-
-
Weiss, K.M.1
Terwilliger, J.D.2
-
23
-
-
0036137130
-
Linkage disequilibrium and the mapping of complex human traits
-
Weiss K.M., Clark A.G. Linkage disequilibrium and the mapping of complex human traits. Trends Genet. 18:2002;19-24.
-
(2002)
Trends Genet.
, vol.18
, pp. 19-24
-
-
Weiss, K.M.1
Clark, A.G.2
-
24
-
-
0021066244
-
Evolutionary relationship of DNA sequences in finite populations
-
Tajima F. Evolutionary relationship of DNA sequences in finite populations. Genetics. 105:1983;437-460.
-
(1983)
Genetics
, vol.105
, pp. 437-460
-
-
Tajima, F.1
-
25
-
-
0036468808
-
Linkage disequilibrium: What history has to tell us
-
Nordborg M., Tavaré S. Linkage disequilibrium: what history has to tell us. Trends Genet. 18:2002;83-90.
-
(2002)
Trends Genet.
, vol.18
, pp. 83-90
-
-
Nordborg, M.1
Tavaré, S.2
-
26
-
-
0015310384
-
The sampling theory of selectively neutral alleles
-
Ewens W.J. The sampling theory of selectively neutral alleles. Theor. Popul. Biol. 3:1972;87-112.
-
(1972)
Theor. Popul. Biol.
, vol.3
, pp. 87-112
-
-
Ewens, W.J.1
-
27
-
-
0035451780
-
On the allelic spectrum of human disease
-
Reich D.E., Lander E.S. On the allelic spectrum of human disease. Trends Genet. 17:2001;502-510.
-
(2001)
Trends Genet.
, vol.17
, pp. 502-510
-
-
Reich, D.E.1
Lander, E.S.2
-
28
-
-
0034969437
-
Are rare variants responsible for susceptibility to complex disease?
-
A well-articulated argument for why it is likely that rare alleles will account for a substantial portion of the risk of complex diseases in humans.
-
Pritchard J.K. Are rare variants responsible for susceptibility to complex disease? Am. J. Hum. Genet. 69:2001;124-137 A well-articulated argument for why it is likely that rare alleles will account for a substantial portion of the risk of complex diseases in humans.
-
(2001)
Am. J. Hum. Genet.
, vol.69
, pp. 124-137
-
-
Pritchard, J.K.1
-
29
-
-
0036799545
-
The allelic architecture of human disease genes: Common disease - Common variant... or not?
-
Pritchard J.K., Cox N.J. The allelic architecture of human disease genes: common disease - common variant... or not? Hum. Mol. Genet. 11:2002;2417-2423.
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 2417-2423
-
-
Pritchard, J.K.1
Cox, N.J.2
-
30
-
-
0027469970
-
Optimality, mutation and the evolution of ageing
-
Partridge L., Barton N.H. Optimality, mutation and the evolution of ageing. Nature. 362:1993;305-311.
-
(1993)
Nature
, vol.362
, pp. 305-311
-
-
Partridge, L.1
Barton, N.H.2
-
31
-
-
0037303468
-
A polygenic basis for late-onset diseases
-
Wright A., Charlesworth B., Rudan I., Carothers A., Campbell H. A polygenic basis for late-onset diseases. Trends Genet. 19:2003;97-106.
-
(2003)
Trends Genet.
, vol.19
, pp. 97-106
-
-
Wright, A.1
Charlesworth, B.2
Rudan, I.3
Carothers, A.4
Campbell, H.5
-
32
-
-
0027377799
-
Transmission test for linkage disequilibrium: The insulin gene region and insulin-dependent diabetes mellitus (IDDM)
-
Spielman R.S., McGinnis R.E., Ewens W.J. Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). Am. J. Hum. Genet. 52:1993;506-516.
-
(1993)
Am. J. Hum. Genet.
, vol.52
, pp. 506-516
-
-
Spielman, R.S.1
McGinnis, R.E.2
Ewens, W.J.3
-
33
-
-
0033930943
-
Estimation of admixture and detection of linkage in admixed populations by a Bayesian approach: Application to African-American populations
-
McKeigue P.M., Carpenter J.R., Parra E.J., Shriver M.D. Estimation of admixture and detection of linkage in admixed populations by a Bayesian approach: application to African-American populations. Ann. Hum. Genet. 64:2000;171-186.
-
(2000)
Ann. Hum. Genet.
, vol.64
, pp. 171-186
-
-
McKeigue, P.M.1
Carpenter, J.R.2
Parra, E.J.3
Shriver, M.D.4
-
34
-
-
0036157464
-
Complex signatures of natural selection at the Duffy blood group locus
-
Hamblin M., Thompson E.E., Di Rienzo A. Complex signatures of natural selection at the Duffy blood group locus. Am. J. Hum. Genet. 70:2002;369-383.
-
(2002)
Am. J. Hum. Genet.
, vol.70
, pp. 369-383
-
-
Hamblin, M.1
Thompson, E.E.2
Di Rienzo, A.3
-
35
-
-
0035919696
-
Haplotype diversity and linkage disequilibrium at human G6PD: Recent origin of alleles that confer malarial resistance
-
Tishkoff S.A., Varkonyi R., Cahinhinan N., Abbes S., Argyropoulos G., Destro-Bisol G., Drousiotou A., Dangerfield B., Lefranc G., Loiselet J.et al. Haplotype diversity and linkage disequilibrium at human G6PD: recent origin of alleles that confer malarial resistance. Science. 293:2001;455-462.
-
(2001)
Science
, vol.293
, pp. 455-462
-
-
Tishkoff, S.A.1
Varkonyi, R.2
Cahinhinan, N.3
Abbes, S.4
Argyropoulos, G.5
Destro-Bisol, G.6
Drousiotou, A.7
Dangerfield, B.8
Lefranc, G.9
Loiselet, J.10
-
36
-
-
0024313579
-
Statistical method for testing the neutral mutation hypothesis by DNA polymorphism
-
Tajima F. Statistical method for testing the neutral mutation hypothesis by DNA polymorphism. Genetics. 123:1989;585-595.
-
(1989)
Genetics
, vol.123
, pp. 585-595
-
-
Tajima, F.1
-
37
-
-
0027453041
-
Statistical tests of neutrality of mutations
-
Fu Y.X., Li W.H. Statistical tests of neutrality of mutations. Genetics. 133:1993;693-709.
-
(1993)
Genetics
, vol.133
, pp. 693-709
-
-
Fu, Y.X.1
Li, W.H.2
-
38
-
-
0023339852
-
A test of neutral molecular evolution based on nucleotide data
-
Hudson R.R., Kreitman M., Aguadé M. A test of neutral molecular evolution based on nucleotide data. Genetics. 116:1987;153-159.
-
(1987)
Genetics
, vol.116
, pp. 153-159
-
-
Hudson, R.R.1
Kreitman, M.2
Aguadé, M.3
-
39
-
-
0026428610
-
Adaptive protein evolution at the Adh locus in Drosophila
-
McDonald J.H., Kreitman M. Adaptive protein evolution at the Adh locus in Drosophila. Nature. 351:1991;652-654.
-
(1991)
Nature
, vol.351
, pp. 652-654
-
-
McDonald, J.H.1
Kreitman, M.2
-
40
-
-
0030683599
-
PAML: A program for phylogenetic analysis by maximum likelihood
-
Yang Z. PAML: a program for phylogenetic analysis by maximum likelihood. Comput. Appl. Biosci. 13:1997;555-556.
-
(1997)
Comput. Appl. Biosci.
, vol.13
, pp. 555-556
-
-
Yang, Z.1
-
41
-
-
0036911353
-
Interrogating a high-density SNP map for signatures of natural selection
-
Akey J.M., Zhang G., Zhang K., Jin L., Shriver M.D. Interrogating a high-density SNP map for signatures of natural selection. Genome Res. 12:2002;1805-1814.
-
(2002)
Genome Res.
, vol.12
, pp. 1805-1814
-
-
Akey, J.M.1
Zhang, G.2
Zhang, K.3
Jin, L.4
Shriver, M.D.5
-
42
-
-
0034924997
-
Positive and negative selection on the human genome
-
Fay J.C., Wyckoff G.J., Wu C.I. Positive and negative selection on the human genome. Genetics. 158:2001;1227-1234.
-
(2001)
Genetics
, vol.158
, pp. 1227-1234
-
-
Fay, J.C.1
Wyckoff, G.J.2
Wu, C.I.3
-
43
-
-
0034791035
-
High-resolution haplotype structure in the human genome
-
One of the first papers to establish the existence and importance of haplotype blocks.
-
Daly M.J., Rioux J.D., Schaffner S.F., Hudson T.J., Lander E.S. High-resolution haplotype structure in the human genome. Nat. Genet. 29:2001;229-232 One of the first papers to establish the existence and importance of haplotype blocks.
-
(2001)
Nat. Genet.
, vol.29
, pp. 229-232
-
-
Daly, M.J.1
Rioux, J.D.2
Schaffner, S.F.3
Hudson, T.J.4
Lander, E.S.5
-
44
-
-
0035941029
-
Blocks of limited haplotype diversity revealed by high-resolution scanning of human chromosome 21
-
A stunning demonstration of sequencing by hybridization, done on human-rodent cell hybrids that possess only a single human chromosome 21, so that all the data from a single cell line are truly representative of one haplotype.
-
Patil N., Berno A.J., Hinds D.A., Barrett W.A., Doshi J.M., Hacker C.R., Kautzer C.R., Lee D.H., Marjoribanks C., McDonough D.P.et al. Blocks of limited haplotype diversity revealed by high-resolution scanning of human chromosome 21. Science. 294:2001;1719-1723 A stunning demonstration of sequencing by hybridization, done on human-rodent cell hybrids that possess only a single human chromosome 21, so that all the data from a single cell line are truly representative of one haplotype.
-
(2001)
Science
, vol.294
, pp. 1719-1723
-
-
Patil, N.1
Berno, A.J.2
Hinds, D.A.3
Barrett, W.A.4
Doshi, J.M.5
Hacker, C.R.6
Kautzer, C.R.7
Lee, D.H.8
Marjoribanks, C.9
McDonough, D.P.10
-
45
-
-
0037370629
-
Using haplotype blocks to map human complex trait loci
-
Cardon L.R., Abecasis G.R. Using haplotype blocks to map human complex trait loci. Trends Genet. 19:2003;135-140.
-
(2003)
Trends Genet.
, vol.19
, pp. 135-140
-
-
Cardon, L.R.1
Abecasis, G.R.2
-
46
-
-
0037370466
-
Chromosome-wide distribution of haplotype blocks and the role of recombination hot spots
-
This paper provides a thoughtful analysis of the LD and haplotype structure inferred from SNPs on chromosome 19. The authors find that only about one-third of the chromosome is covered by haplotype blocks, and simulations show that there is no reason to have to invoke recombination hotspots in order to explain the observed blocks.
-
Phillips M.S., Lawrence R., Sachidanandam R., Morris A.P., Balding D.J., Donaldson M.A., Studebaker J.F., Ankener W.M., Alfisi S.V., Kuo F.S.et al. Chromosome-wide distribution of haplotype blocks and the role of recombination hot spots. Nat. Genet. 33:2003;382-387 This paper provides a thoughtful analysis of the LD and haplotype structure inferred from SNPs on chromosome 19. The authors find that only about one-third of the chromosome is covered by haplotype blocks, and simulations show that there is no reason to have to invoke recombination hotspots in order to explain the observed blocks.
-
(2003)
Nat. Genet.
, vol.33
, pp. 382-387
-
-
Phillips, M.S.1
Lawrence, R.2
Sachidanandam, R.3
Morris, A.P.4
Balding, D.J.5
Donaldson, M.A.6
Studebaker, J.F.7
Ankener, W.M.8
Alfisi, S.V.9
Kuo, F.S.10
-
47
-
-
0035027837
-
Why is there so little intragenic linkage disequilibrium in humans?
-
This paper attempts to fit the pattern of decay of LD with physical distance in the human genome to population genetic models and finds an important discrepancy. The observed decay in LD is faster than expected (based on direct estimates of recombination rate), especially at short distances. Possible explanations - including gene conversion, population growth, and hypermutation of CpG dinucleotides - all fail to fully accommodate the observed decay in LD.
-
Przeworski M., Wall J.D. Why is there so little intragenic linkage disequilibrium in humans? Genet. Res. 77:2001;143-151 This paper attempts to fit the pattern of decay of LD with physical distance in the human genome to population genetic models and finds an important discrepancy. The observed decay in LD is faster than expected (based on direct estimates of recombination rate), especially at short distances. Possible explanations - including gene conversion, population growth, and hypermutation of CpG dinucleotides - all fail to fully accommodate the observed decay in LD.
-
(2001)
Genet. Res.
, vol.77
, pp. 143-151
-
-
Przeworski, M.1
Wall, J.D.2
-
48
-
-
0034835229
-
Gene conversion and different population histories may explain the contrast between polymorphism and linkage disequilibrium levels
-
Frisse L., Hudson R.R., Bartoszewicz A., Wall J.D., Donfack J., Di Rienzo A. Gene conversion and different population histories may explain the contrast between polymorphism and linkage disequilibrium levels. Am. J. Hum. Genet. 69:2001;831-843.
-
(2001)
Am. J. Hum. Genet.
, vol.69
, pp. 831-843
-
-
Frisse, L.1
Hudson, R.R.2
Bartoszewicz, A.3
Wall, J.D.4
Donfack, J.5
Di Rienzo, A.6
-
49
-
-
0034789532
-
Haplotype tagging for the identification of common disease genes
-
Johnson G.C., Esposito L., Barratt B.J., Smith A.N., Heward J., Di Genova G., Ueda H., Cordell H.J., Eaves I.A., Dudbridge F.et al. Haplotype tagging for the identification of common disease genes. Nat. Genet. 29:2001;233-237.
-
(2001)
Nat. Genet.
, vol.29
, pp. 233-237
-
-
Johnson, G.C.1
Esposito, L.2
Barratt, B.J.3
Smith, A.N.4
Heward, J.5
Di Genova, G.6
Ueda, H.7
Cordell, H.J.8
Eaves, I.A.9
Dudbridge, F.10
-
50
-
-
0025269067
-
Inference of haplotypes from PCR-amplified samples of diploid populations
-
Clark A.G. Inference of haplotypes from PCR-amplified samples of diploid populations. Mol. Biol. Evol. 7:1990;111-122.
-
(1990)
Mol. Biol. Evol.
, vol.7
, pp. 111-122
-
-
Clark, A.G.1
-
51
-
-
0035071957
-
A new statistical method for haplotype reconstruction from population data
-
This is the paper that describes the algorithm behind PHASE, one of the popular haplotype inference programs in wide use. One of the more elegant applications of Bayesian inference in modern statistical genetics.
-
Stephens M., Smith N.J., Donnelly P. A new statistical method for haplotype reconstruction from population data. Am. J. Hum. Genet. 68:2001;978-989 This is the paper that describes the algorithm behind PHASE, one of the popular haplotype inference programs in wide use. One of the more elegant applications of Bayesian inference in modern statistical genetics.
-
(2001)
Am. J. Hum. Genet.
, vol.68
, pp. 978-989
-
-
Stephens, M.1
Smith, N.J.2
Donnelly, P.3
-
52
-
-
0036138183
-
Bayesian haplotype inference for multiple linked single-nucleotide polymorphisms
-
Niu T., Qin Z.S., Xu X., Liu J.S. Bayesian haplotype inference for multiple linked single-nucleotide polymorphisms. Am. J. Hum. Genet. 70:2002;157-169.
-
(2002)
Am. J. Hum. Genet.
, vol.70
, pp. 157-169
-
-
Niu, T.1
Qin, Z.S.2
Xu, X.3
Liu, J.S.4
-
53
-
-
0036844521
-
Partition-ligation-expectation-maximization algorithm for haplotype inference with single-nucleotide polymorphisms
-
Qin Z.S., Niu T., Liu J.S. Partition-ligation-expectation-maximization algorithm for haplotype inference with single-nucleotide polymorphisms. Am. J. Hum. Genet. 71:2002;1242-1247.
-
(2002)
Am. J. Hum. Genet.
, vol.71
, pp. 1242-1247
-
-
Qin, Z.S.1
Niu, T.2
Liu, J.S.3
-
54
-
-
0034812677
-
Inference of haplotypes from samples of diploid populations: Complexity and algorithms
-
Gusfield D. Inference of haplotypes from samples of diploid populations: complexity and algorithms. J. Comput. Biol. 8:2001;305-323.
-
(2001)
J. Comput. Biol.
, vol.8
, pp. 305-323
-
-
Gusfield, D.1
-
55
-
-
0037168559
-
High-throughput screening for evidence of association by using mass spectrometry genotyping on DNA pools
-
Mohlke K.L., Erdos M.R., Scott L.J., Fingerlin T.E., Jackson A.U., Silander K., Hollstein P., Boehnke M., Collins F.S. High-throughput screening for evidence of association by using mass spectrometry genotyping on DNA pools. Proc. Natl. Acad Sci. USA. 99:2002;16928-16933.
-
(2002)
Proc. Natl. Acad Sci. USA
, vol.99
, pp. 16928-16933
-
-
Mohlke, K.L.1
Erdos, M.R.2
Scott, L.J.3
Fingerlin, T.E.4
Jackson, A.U.5
Silander, K.6
Hollstein, P.7
Boehnke, M.8
Collins, F.S.9
-
57
-
-
0037312921
-
Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease
-
Lohmueller K.E., Pearce C.L., Pike M., Lander E.S., Hirschhorn J.N. Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease. Nat. Genet. 33:2003;177-182.
-
(2003)
Nat. Genet.
, vol.33
, pp. 177-182
-
-
Lohmueller, K.E.1
Pearce, C.L.2
Pike, M.3
Lander, E.S.4
Hirschhorn, J.N.5
|