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Volumn 33, Issue 5-6, 2003, Pages 551-558

Transient receptor potential (TRP) channels as potential drug targets in respiratory disease

Author keywords

Asthma; Chronic obstructive pulmonary disease; Macrophages; ROCC; T lymphocytes; TRP

Indexed keywords

1 [2 (4 METHOXYPHENYL) 2 [3 (4 METHOXYPHENYL)PROPOXY]ETHYL] 1H IMIDAZOLE; ANTIINFLAMMATORY AGENT; CALCIUM CHANNEL; CALCIUM ION; CANNABINOID RECEPTOR ANTAGONIST; CAPSAZEPINE; MEMBRANE PROTEIN; MENTHOL; RESPIRATORY TRACT AGENT; THAPSIGARGIN; TRANSIENT RECEPTOR POTENTIAL PROTEIN; UNCLASSIFIED DRUG;

EID: 0038311743     PISSN: 01434160     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0143-4160(03)00060-5     Document Type: Article
Times cited : (57)

References (79)
  • 1
    • 0031001720 scopus 로고    scopus 로고
    • Alternative projections of mortality and disability by cause 1990-2020: Global burden of disease study
    • C.J. Murray, A.D. Lopez, Alternative projections of mortality and disability by cause 1990-2020: global burden of disease study, Lancet 349 (1997) 1498-1504.
    • (1997) Lancet , vol.349 , pp. 1498-1504
    • Murray, C.J.1    Lopez, A.D.2
  • 2
    • 0032944133 scopus 로고    scopus 로고
    • Reversing the trend: Reducing the prevalence of asthma
    • J.K. Peat, J. Li, Reversing the trend: reducing the prevalence of asthma, J. Allergy Clin. Immunol. 103 (1999) 1-10.
    • (1999) J. Allergy Clin. Immunol. , vol.103 , pp. 1-10
    • Peat, J.K.1    Li, J.2
  • 3
    • 0032191115 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease: New opportunities for drug development
    • P.J. Barnes, Chronic obstructive pulmonary disease: new opportunities for drug development, Trends Pharmacol. Sci. 19 (1998) 415-423.
    • (1998) Trends Pharmacol. Sci. , vol.19 , pp. 415-423
    • Barnes, P.J.1
  • 4
    • 0036598241 scopus 로고    scopus 로고
    • New treatments for COPD
    • P.J. Barnes, New treatments for COPD, Nat. Rev. Drug Discov. 1 (2002) 437-446.
    • (2002) Nat. Rev. Drug Discov. , vol.1 , pp. 437-446
    • Barnes, P.J.1
  • 6
    • 0025760379 scopus 로고
    • Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma
    • Q. Hamid, M. Azzawi, S. Ying, et al., Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma, J. Clin. Invest. 87 (1991) 1541-1546.
    • (1991) J. Clin. Invest. , vol.87 , pp. 1541-1546
    • Hamid, Q.1    Azzawi, M.2    Ying, S.3
  • 7
    • 10544256182 scopus 로고    scopus 로고
    • IL-4 and IL-5 mRNA and protein in bronchial biopsies from patients with atopic and nonatopic asthma: Evidence against "intrinsic" asthma being a distinct immunopathologic entity
    • M. Humbert, S.R. Durham, S. Ying, et al., IL-4 and IL-5 mRNA and protein in bronchial biopsies from patients with atopic and nonatopic asthma: evidence against "intrinsic" asthma being a distinct immunopathologic entity, Am. J. Respir. Crit. Care Med. 154 (1996) 1497-1504.
    • (1996) Am. J. Respir. Crit. Care Med. , vol.154 , pp. 1497-1504
    • Humbert, M.1    Durham, S.R.2    Ying, S.3
  • 8
    • 0025611180 scopus 로고
    • Identification of activated T lymphocytes and eosinophils in bronchial biopsies in stable atopic asthma
    • M. Azzawi, B. Bradley, RK. Jeffery, et al., Identification of activated T lymphocytes and eosinophils in bronchial biopsies in stable atopic asthma, Am, Rev. Respir. Dis. 142 (1990) 1407-1413.
    • (1990) Am. Rev. Respir. Dis. , vol.142 , pp. 1407-1413
    • Azzawi, M.1    Bradley, B.2    Jeffery, R.K.3
  • 9
    • 0031954369 scopus 로고    scopus 로고
    • Structural and inflammatory changes in COPD: A comparison with asthma
    • P.K. Jeffery, Structural and inflammatory changes in COPD: a comparison with asthma, Thorax 53 (1998) 129-136.
    • (1998) Thorax , vol.53 , pp. 129-136
    • Jeffery, P.K.1
  • 10
    • 0026666718 scopus 로고
    • Allergic and nonallergic asthmatics have distinct patterns of T-cell activation and cytokine production in peripheral blood and bronchoalveolar lavage
    • C. Walker, E. Bode, L. Boer, T.T. Hansel, K. Blaser, J.C. Virchow Jr., Allergic and nonallergic asthmatics have distinct patterns of T-cell activation and cytokine production in peripheral blood and bronchoalveolar lavage, Am. Rev. Respir. Dis. 146 (1992) 109-115.
    • (1992) Am. Rev. Respir. Dis. , vol.146 , pp. 109-115
    • Walker, C.1    Bode, E.2    Boer, L.3    Hansel, T.T.4    Blaser, K.5    Virchow J.C., Jr.6
  • 11
    • 0022930220 scopus 로고
    • The eosinophilic leukocyte: Structure and function
    • G.J. Gleich, C.R. Adolphson, The eosinophilic leukocyte: structure and function, Adv. Immunol. 39 (1986) 177-253.
    • (1986) Adv. Immunol. , vol.39 , pp. 177-253
    • Gleich, G.J.1    Adolphson, C.R.2
  • 12
    • 0028841154 scopus 로고
    • Eosinophils: Biology and role in disease
    • A.J. Wardlaw, R. Moqbel, A.B. Kay, Eosinophils: biology and role in disease, Adv. Immunol. 60 (1995) 151-266.
    • (1995) Adv. Immunol. , vol.60 , pp. 151-266
    • Wardlaw, A.J.1    Moqbel, R.2    Kay, A.B.3
  • 13
    • 0027971976 scopus 로고
    • Elastolytic metalloproteinases produced by human mononuclear phagocytes. Potential roles in destructive lung disease
    • S.D. Shapiro, Elastolytic metalloproteinases produced by human mononuclear phagocytes. Potential roles in destructive lung disease, Am. J. Respir. Crit. Care Med. 150 (1994) S160-SI64.
    • (1994) Am. J. Respir. Crit. Care Med. , vol.150
    • Shapiro, S.D.1
  • 14
    • 0032603798 scopus 로고    scopus 로고
    • Mechanisms of hypersecretion in acute asthma, proposed cause of death, and novel therapy
    • J.A. Nadel, K. Takeyama, Mechanisms of hypersecretion in acute asthma, proposed cause of death, and novel therapy, Pediatr. Pulmonol. Suppl. 18 (1999) 54-55.
    • (1999) Pediatr. Pulmonol. Suppl. , vol.18 , pp. 54-55
    • Nadel, J.A.1    Takeyama, K.2
  • 15
    • 0030071687 scopus 로고    scopus 로고
    • Differences in interleukin-8 and tumor necrosis factor-alpha in induced sputum from patients with chronic obstructive pulmonary disease or asthma
    • V.M. Keatings, P.D. Collins, D.M. Scott, P.J. Barnes, Differences in interleukin-8 and tumor necrosis factor-alpha in induced sputum from patients with chronic obstructive pulmonary disease or asthma, Am. J. Respir. Crit. Care Med. 153 (1996) 530-534.
    • (1996) Am. J. Respir. Crit. Care Med. , vol.153 , pp. 530-534
    • Keatings, V.M.1    Collins, P.D.2    Scott, D.M.3    Barnes, P.J.4
  • 17
    • 0030061718 scopus 로고    scopus 로고
    • Airflow limitation in chronic bronchitis is associated with T-lymphocyte and macrophage infiltration of the bronchial mucosa
    • A. Di Stefano, G. Turato, P. Maestrelli, et al., Airflow limitation in chronic bronchitis is associated with T-lymphocyte and macrophage infiltration of the bronchial mucosa, Am. J. Respir. Crit. Care Med. 153 (1996) 629-632.
    • (1996) Am. J. Respir. Crit. Care Med. , vol.153 , pp. 629-632
    • Di Stefano, A.1    Turato, G.2    Maestrelli, P.3
  • 18
    • 0010441960 scopus 로고    scopus 로고
    • Inflammatory cells in the airway surface epithelium of smokers with and without bronchitic airflow obstruction
    • T.C. O'Shaughnessy, T. Ansari, N.C. Barnes, P.K. Jeffery, Inflammatory cells in the airway surface epithelium of smokers with and without bronchitic airflow obstruction, Eur. Respir. J. 9 (Suppl 23) (1996) 14S.
    • (1996) Eur. Respir. J. , vol.9 , Issue.SUPPL. 23
    • O'Shaughnessy, T.C.1    Ansari, T.2    Barnes, N.C.3    Jeffery, P.K.4
  • 19
    • 0030900606 scopus 로고    scopus 로고
    • Inflammation in bronchial biopsies of subjects with chronic bronchitis: Inverse relationship of CD8+ T lymphocytes with FEV1
    • T.C. O'Shaughnessy, T.W. Ansari, N.C. Barnes, P.K. Jeffery, Inflammation in bronchial biopsies of subjects with chronic bronchitis: inverse relationship of CD8+ T lymphocytes with FEV1, Am. J. Respir. Crit. Care Med. 155 (1997) 852-857.
    • (1997) Am. J. Respir. Crit. Care Med. , vol.155 , pp. 852-857
    • O'Shaughnessy, T.C.1    Ansari, T.W.2    Barnes, N.C.3    Jeffery, P.K.4
  • 20
    • 0032014542 scopus 로고    scopus 로고
    • CD8+ T-lymphocytes in peripheral airways of smokers with chronic obstructive pulmonary disease
    • M. Saetta, A. Di Stefano, G. Turato, et al., CD8+ T-lymphocytes in peripheral airways of smokers with chronic obstructive pulmonary disease, Am. J. Respir. Crit. Care Med. 157 (1998) 822-826.
    • (1998) Am. J. Respir. Crit. Care Med. , vol.157 , pp. 822-826
    • Saetta, M.1    Di Stefano, A.2    Turato, G.3
  • 21
    • 0033994635 scopus 로고    scopus 로고
    • Mechanisms in COPD: Differences from asthma
    • P.J. Barnes, Mechanisms in COPD: differences from asthma, Chest 117 (2000) 10S-14S.
    • (2000) Chest , vol.117
    • Barnes, P.J.1
  • 23
    • 0038290655 scopus 로고
    • Drugs affecting calcium ions in airway smooth muscle
    • P.J. Barnes (Ed.), IBC publications, London
    • I. Rodger, Drugs affecting calcium ions in airway smooth muscle, in: P.J. Barnes (Ed.), New Drugs for Asthma, IBC publications, London, 1989, pp. 455-456.
    • (1989) New Drugs for Asthma , pp. 455-456
    • Rodger, I.1
  • 24
    • 0025865173 scopus 로고
    • Receptor-activated calcium influx in human airway smooth muscle cells
    • R.K. Murray, M.I. Kotlikoff, Receptor-activated calcium influx in human airway smooth muscle cells, J. Physiol. 435 (1991) 123-144.
    • (1991) J. Physiol. , vol.435 , pp. 123-144
    • Murray, R.K.1    Kotlikoff, M.I.2
  • 25
    • 0031594397 scopus 로고    scopus 로고
    • Leukotriene D4 contractions in human airways are blocked by SK&F 96365, an inhibitor of receptor-mediated calcium entry
    • I. Gorenne, C. Labat, J.P. Gascard, X. Norel, N. Nashashibi, C. Brink, Leukotriene D4 contractions in human airways are blocked by SK&F 96365, an inhibitor of receptor-mediated calcium entry, J. Pharmacol. Exp. Ther. 284 (1998) 549-552.
    • (1998) J. Pharmacol. Exp. Ther. , vol.284 , pp. 549-552
    • Gorenne, I.1    Labat, C.2    Gascard, J.P.3    Norel, X.4    Nashashibi, N.5    Brink, C.6
  • 26
  • 29
    • 0033836324 scopus 로고    scopus 로고
    • Endothelin-1 is a potent activator of nonselective cation currents in human bronchial smooth muscle cells
    • H. Oonuma, T. Nakajima, T. Nagata, et al., Endothelin-1 is a potent activator of nonselective cation currents in human bronchial smooth muscle cells, Am. J. Respir. Cell Mol. Biol. 23 (2000) 213-221.
    • (2000) Am. J. Respir. Cell Mol. Biol. , vol.23 , pp. 213-221
    • Oonuma, H.1    Nakajima, T.2    Nagata, T.3
  • 32
    • 0037096972 scopus 로고    scopus 로고
    • Specific detection of the endogenous transient receptor potential (TRP)-1 protein in liver and airway smooth muscle cells using immunoprecipitation and Western-blot analysis
    • H.L. Ong, J. Chen, T. Chataway, et al., Specific detection of the endogenous transient receptor potential (TRP)-1 protein in liver and airway smooth muscle cells using immunoprecipitation and Western-blot analysis, Biochem. J. 364 (2002) 641-648.
    • (2002) Biochem. J. , vol.364 , pp. 641-648
    • Ong, H.L.1    Chen, J.2    Chataway, T.3
  • 35
    • 0037155047 scopus 로고    scopus 로고
    • Transient receptor potential channels regulate myogenic tone of resistance arteries
    • D.G. Welsh, A.D. Morielli, M.T. Nelson, J.E. Brayden, Transient receptor potential channels regulate myogenic tone of resistance arteries, Circ. Res. 90 (2002) 248-250.
    • (2002) Circ. Res. , vol.90 , pp. 248-250
    • Welsh, D.G.1    Morielli, A.D.2    Nelson, M.T.3    Brayden, J.E.4
  • 37
    • 0037032988 scopus 로고    scopus 로고
    • CaT1 contributes to the store-operated calcium current in Jurkat T-lymphocytes
    • J. Cui, J.S. Bian, A. Kagan, T.V. McDonald, CaT1 contributes to the store-operated calcium current in Jurkat T-lymphocytes, J. Biol. Chem. 277 (2002) 47175-47183.
    • (2002) J. Biol. Chem. , vol.277 , pp. 47175-47183
    • Cui, J.1    Bian, J.S.2    Kagan, A.3    McDonald, T.V.4
  • 38
    • 0026594980 scopus 로고
    • Depletion of intracellular calcium stores activates a calcium current in mast cells
    • M. Hoth, R. Penner, Depletion of intracellular calcium stores activates a calcium current in mast cells, Nature 355 (1992) 353-356.
    • (1992) Nature , vol.355 , pp. 353-356
    • Hoth, M.1    Penner, R.2
  • 39
    • 0035064074 scopus 로고    scopus 로고
    • Calcium signaling mechanisms in T lymphocytes
    • R.S. Lewis, Calcium signaling mechanisms in T lymphocytes, Annu. Rev. Immunol. 19 (2001) 497-521.
    • (2001) Annu. Rev. Immunol. , vol.19 , pp. 497-521
    • Lewis, R.S.1
  • 40
    • 0028987597 scopus 로고
    • 2+ availability involved in antigen-induced airway hyperresponsiveness in rats
    • 2+ availability involved in antigen-induced airway hyperresponsiveness in rats, Eur. J. Pharmacol. 278 (1995) 79-82.
    • (1995) Eur. J. Pharmacol. , vol.278 , pp. 79-82
    • Chiba, Y.1    Misawa, M.2
  • 41
    • 0033162068 scopus 로고    scopus 로고
    • Translocation of a calcium-permeable cation channel induced by insulin-like growth factor-I
    • M. Kanzaki, Y.Q. Zhang, H. Mashima, L. Li, H. Shibata, I. Kojima, Translocation of a calcium-permeable cation channel induced by insulin-like growth factor-I, Nat. Cell Biol. 1 (1999) 165-170.
    • (1999) Nat. Cell Biol. , vol.1 , pp. 165-170
    • Kanzaki, M.1    Zhang, Y.Q.2    Mashima, H.3    Li, L.4    Shibata, H.5    Kojima, I.6
  • 42
    • 0037179755 scopus 로고    scopus 로고
    • p38 MAPK activation by NGF in primary sensory neurons after inflammation increases TRPV1 levels and maintains heat hyperalgesia
    • R.R. Ji, T.A. Samad, S.X. Jin, R. Schmoll, C.J. Woolf, p38 MAPK activation by NGF in primary sensory neurons after inflammation increases TRPV1 levels and maintains heat hyperalgesia, Neuron 36 (2002) 57-68.
    • (2002) Neuron. , vol.36 , pp. 57-68
    • Ji, R.R.1    Samad, T.A.2    Jin, S.X.3    Schmoll, R.4    Woolf, C.J.5
  • 43
    • 0036308546 scopus 로고    scopus 로고
    • Chronic cough and the cough reflex in common lung diseases
    • T. Higenbottam, Chronic cough and the cough reflex in common lung diseases, Pulm. Pharmacol. Ther. 15 (2002) 241-247.
    • (2002) Pulm. Pharmacol. Ther. , vol.15 , pp. 241-247
    • Higenbottam, T.1
  • 45
    • 0029080141 scopus 로고
    • Resiniferatoxin binding to vanilloid receptors in guinea pig and human airways
    • A. Szallasi, C. Goso, S. Manzini, Resiniferatoxin binding to vanilloid receptors in guinea pig and human airways, Am. J. Respir. Crit. Care Med. 152 (1995) 59-63.
    • (1995) Am. J. Respir. Crit. Care Med. , vol.152 , pp. 59-63
    • Szallasi, A.1    Goso, C.2    Manzini, S.3
  • 46
    • 0033103354 scopus 로고    scopus 로고
    • Differential expression of the mRNA for the vanilloid receptor subtype 1 in cells of the adult rat dorsal root and nodose ganglia and its downregulation by axotomy
    • G.J. Michael, J.V. Priestley, Differential expression of the mRNA for the vanilloid receptor subtype 1 in cells of the adult rat dorsal root and nodose ganglia and its downregulation by axotomy, J. Neurosci. 19 (1999) 1844-1854.
    • (1999) J. Neurosci. , vol.19 , pp. 1844-1854
    • Michael, G.J.1    Priestley, J.V.2
  • 47
    • 0034816906 scopus 로고    scopus 로고
    • Enhanced lung C-fiber responsiveness in sensitized adult guinea pigs exposed to chronic tobacco smoke
    • D.R. Bergren, Enhanced lung C-fiber responsiveness in sensitized adult guinea pigs exposed to chronic tobacco smoke, J. Appl. Physiol. 91 (2001) 1645-1654.
    • (2001) J. Appl. Physiol. , vol.91 , pp. 1645-1654
    • Bergren, D.R.1
  • 48
  • 49
    • 0034646740 scopus 로고    scopus 로고
    • Impaired nociception and pain sensation in mice lacking the capsaicin receptor
    • M.J. Caterina, A. Leffler, A.B. Malmberg, et al., Impaired nociception and pain sensation in mice lacking the capsaicin receptor, Science 288 (2000) 306-313.
    • (2000) Science , vol.288 , pp. 306-313
    • Caterina, M.J.1    Leffler, A.2    Malmberg, A.B.3
  • 50
    • 0036605663 scopus 로고    scopus 로고
    • Hot channels in airways: Pharmacology of the vanilloid receptor
    • S.W. Hwang, U. Oh, Hot channels in airways: pharmacology of the vanilloid receptor, Curr. Opin. Pharmacol. 2 (2002) 235-242.
    • (2002) Curr. Opin. Pharmacol. , vol.2 , pp. 235-242
    • Hwang, S.W.1    Oh, U.2
  • 51
    • 18344386202 scopus 로고    scopus 로고
    • A TRP channel that senses cold stimuli and menthol
    • A.M. Peier, A. Moqrich, A.C. Hergarden, et al., A TRP channel that senses cold stimuli and menthol, Cell 108 (2002) 705-715.
    • (2002) Cell , vol.108 , pp. 705-715
    • Peier, A.M.1    Moqrich, A.2    Hergarden, A.C.3
  • 52
    • 0037034931 scopus 로고    scopus 로고
    • Identification of a cold receptor reveals a general role for TRP channels in thermosensation
    • D.D. McKemy, W.M. Neuhausser, D. Julius, Identification of a cold receptor reveals a general role for TRP channels in thermosensation, Nature 416 (2002) 52-58.
    • (2002) Nature , vol.416 , pp. 52-58
    • McKemy, D.D.1    Neuhausser, W.M.2    Julius, D.3
  • 53
    • 0028024219 scopus 로고
    • Menthol and related cooling compounds
    • R. Eccles, Menthol and related cooling compounds, J. Pharm. Pharmacol. 46 (1994) 618-630.
    • (1994) J. Pharm. Pharmacol. , vol.46 , pp. 618-630
    • Eccles, R.1
  • 54
    • 0030878592 scopus 로고    scopus 로고
    • Capsaicin and neurokinin A-induced bronchoconstriction in the anaesthetised guinea-pig: Evidence for a direct action of menthol on isolated bronchial smooth muscle
    • C.E. Wright, E.A. Laude, T.J. Grattan, A.H. Morice, Capsaicin and neurokinin A-induced bronchoconstriction in the anaesthetised guinea-pig: evidence for a direct action of menthol on isolated bronchial smooth muscle, Br. J. Pharmacol. 121 (1997) 1645-1650.
    • (1997) Br. J. Pharmacol. , vol.121 , pp. 1645-1650
    • Wright, C.E.1    Laude, E.A.2    Grattan, T.J.3    Morice, A.H.4
  • 55
    • 85029466595 scopus 로고    scopus 로고
    • Expression of TRP (transient receptor potential) homologs in cultured human bronchial epithelium
    • R.L. Corteling, S.W. Li, C.T. Poll, H. Danahay, I.P. Hall, Expression of TRP (transient receptor potential) homologs in cultured human bronchial epithelium, Am. J. Respir. Crit. Care Med. 165 (8) (2002) A69.
    • (2002) Am. J. Respir. Crit. Care Med. , vol.165 , Issue.8
    • Corteling, R.L.1    Li, S.W.2    Poll, C.T.3    Danahay, H.4    Hall, I.P.5
  • 57
    • 0035408171 scopus 로고    scopus 로고
    • Trp1-dependent enhancement of salivary gland fluid secretion: Role of store-operated calcium entry
    • B.B. Singh, C.Y. Zheng, X.B. Liu, et al., Trp1-dependent enhancement of salivary gland fluid secretion: role of store-operated calcium entry, FASEB J. 15 (2001) 1652-1654.
    • (2001) FASEB J. , vol.15 , pp. 1652-1654
    • Singh, B.B.1    Zheng, C.Y.2    Liu, X.B.3
  • 59
    • 0035328671 scopus 로고    scopus 로고
    • Trp-p8, a novel prostate-specific gene, is up-regulated in prostate cancer and other malignancies and shares high homology with transient receptor potential calcium channel proteins
    • L. Tsavaler, M.H. Shapero, S. Morkowski, R. Laus, Trp-p8, a novel prostate-specific gene, is up-regulated in prostate cancer and other malignancies and shares high homology with transient receptor potential calcium channel proteins, Cancer Res. 61 (2001) 3760-3769.
    • (2001) Cancer Res. , vol.61 , pp. 3760-3769
    • Tsavaler, L.1    Shapero, M.H.2    Morkowski, S.3    Laus, R.4
  • 62
    • 0348142491 scopus 로고    scopus 로고
    • Identification and characterization of a novel human vanilloid receptor-like protein, VRL-2
    • N.S. Delany, M. Hurle, P. Facer, et al., Identification and characterization of a novel human vanilloid receptor-like protein, VRL-2, Physiol. Genomics 4 (2001) 165-174.
    • (2001) Physiol. Genomics , vol.4 , pp. 165-174
    • Delany, N.S.1    Hurle, M.2    Facer, P.3
  • 63
    • 0027365908 scopus 로고
    • Stretch-activated channels in airway epithelial cells
    • Y.K. Kim, E.R. Dirksen, M.J. Sanderson, Stretch-activated channels in airway epithelial cells, Am. J. Physiol. 265 (1993) C1306-C1318.
    • (1993) Am. J. Physiol. , vol.265
    • Kim, Y.K.1    Dirksen, E.R.2    Sanderson, M.J.3
  • 66
    • 0037189484 scopus 로고    scopus 로고
    • Activation of the Cation Channel Long Transient Receptor Potential Channel 2 (LTRPC2) by Hydrogen Peroxide. A splice variant reveals a mode of action independent of ADP-ribose
    • E. Wehage, J. Eisfeld, I. Heiner, E. Jungling, C. Zitt, A. Luckhoff, Activation of the Cation Channel Long Transient Receptor Potential Channel 2 (LTRPC2) by Hydrogen Peroxide. A splice variant reveals a mode of action independent of ADP-ribose, J. Biol. Chem. 277 (2002) 23150-23156.
    • (2002) J. Biol. Chem. , vol.277 , pp. 23150-23156
    • Wehage, E.1    Eisfeld, J.2    Heiner, I.3    Jungling, E.4    Zitt, C.5    Luckhoff, A.6
  • 67
    • 0035902767 scopus 로고    scopus 로고
    • 2+ influx system mediated by LTRPC2
    • 2+ influx system mediated by LTRPC2, Science 293 (2001) 1327-1330.
    • (2001) Science , vol.293 , pp. 1327-1330
    • Sano, Y.1    Inamura, K.2    Miyake, A.3
  • 69
    • 0037128653 scopus 로고    scopus 로고
    • 2+ release from endoplasmic reticulum in B lymphocytes
    • 2+ release from endoplasmic reticulum in B lymphocytes, J. Exp. Med. 195 (2002) 673-681.
    • (2002) J. Exp. Med. , vol.195 , pp. 673-681
    • Mori, Y.1    Wakamori, M.2    Miyakawa, T.3
  • 70
    • 0037093468 scopus 로고    scopus 로고
    • Diacylglycerol activates the influx of extracellular cations in T-lymphocytes independently of intracellular calcium-store depletion and possibly involving endogenous TRP6 gene products
    • A. Gamberucci, E. Giurisato, P. Pizzo, et al., Diacylglycerol activates the influx of extracellular cations in T-lymphocytes independently of intracellular calcium-store depletion and possibly involving endogenous TRP6 gene products, Biochem. J. 364 (2002) 245-254.
    • (2002) Biochem. J. , vol.364 , pp. 245-254
    • Gamberucci, A.1    Giurisato, E.2    Pizzo, P.3
  • 71
    • 0025103909 scopus 로고
    • SK&F 96365, a novel inhibitor of receptor-mediated calcium entry
    • J.E. Merritt, W.P. Armstrong, C.D. Benham, et al., SK&F 96365, a novel inhibitor of receptor-mediated calcium entry, Biochem. J. 271 (1990) 515-522.
    • (1990) Biochem. J. , vol.271 , pp. 515-522
    • Merritt, J.E.1    Armstrong, W.P.2    Benham, C.D.3
  • 72
    • 0037090273 scopus 로고    scopus 로고
    • Store-operated calcium entry in human neutrophils reflects multiple contributions from independently regulated pathways
    • K. Itagaki, K.B. Kannan, D.H. Livingston, E.A. Deitch, Z. Fekete, C.J. Hauser, Store-operated calcium entry in human neutrophils reflects multiple contributions from independently regulated pathways, J. Immunol. 168 (2002) 4063-4069.
    • (2002) J. Immunol. , vol.168 , pp. 4063-4069
    • Itagaki, K.1    Kannan, K.B.2    Livingston, D.H.3    Deitch, E.A.4    Fekete, Z.5    Hauser, C.J.6
  • 73
    • 0031561402 scopus 로고    scopus 로고
    • Differential Expression of Mammalian TRP Homologues across Tissues and Cell Lines
    • R.L. Garcia, W.P. Schilling, Differential Expression of Mammalian TRP Homologues across Tissues and Cell Lines, Biochem. Biophys. Res. Commun. 239 (1997) 279-283.
    • (1997) Biochem. Biophys. Res. Commun. , vol.239 , pp. 279-283
    • Garcia, R.L.1    Schilling, W.P.2
  • 74
    • 0035810243 scopus 로고    scopus 로고
    • CaT1 manifests the pore properties of the calcium-release-activated calcium channel
    • L. Yue, J.B. Peng, M.A. Hediger, D.E. Clapham, CaT1 manifests the pore properties of the calcium-release-activated calcium channel, Nature 410 (2001) 705-709.
    • (2001) Nature , vol.410 , pp. 705-709
    • Yue, L.1    Peng, J.B.2    Hediger, M.A.3    Clapham, D.E.4
  • 76
    • 0035999837 scopus 로고    scopus 로고
    • 2+-inhibited cation (MIC) channels
    • 2+-inhibited cation (MIC) channels, J. Gen. Physiol. 119 (5 ) (2002) 487-507.
    • (2002) J. Gen. Physiol. , vol.119 , Issue.5 , pp. 487-507
    • Prakriya, M.1    Lewis, R.S.2
  • 77
    • 0035978239 scopus 로고    scopus 로고
    • LTRPC7 is a Mg.ATP-regulated divalent cation channel required for cell viability
    • M.J. Nadler, M.C. Hermosura, K. Inabe, et al., LTRPC7 is a Mg.ATP-regulated divalent cation channel required for cell viability, Nature 411 (2001) 590-595.
    • (2001) Nature , vol.411 , pp. 590-595
    • Nadler, M.J.1    Hermosura, M.C.2    Inabe, K.3
  • 78
    • 0036092076 scopus 로고    scopus 로고
    • The TRPM7 channel is inactivated by PIP(2) hydrolysis
    • L.W. Runnels, L. Yue, D.E. Clapham, The TRPM7 channel is inactivated by PIP(2) hydrolysis, Nat. Cell Biol. 4 (2002) 329-336.
    • (2002) Nat. Cell Biol. , vol.4 , pp. 329-336
    • Runnels, L.W.1    Yue, L.2    Clapham, D.E.3
  • 79
    • 0037067430 scopus 로고    scopus 로고
    • 2+ channel in trp4 knockout mice interferes with increase in microvascular endothelial permeability
    • 2+ channel in trp4 knockout mice interferes with increase in microvascular endothelial permeability, FASEB J. 91 (1)
    • (2002) FASEB J. , vol.91 , Issue.1 , pp. 70-76
    • Tiruppathi, C.1    Vogel, S.M.2    Freichel, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.