Overexpression of toll-like receptor 4 amplifies the host response to lipopolysaccharide and provides a survival advantage in transgenic mice

Journal of Immunology

Volumn 170, Issue 12, 2003, Pages 6141-6150

  Bihl, Franck ^a,b,c   Salez, Laurent ^b   Beaubier, Magali ^c   Torres, David ^c   Larivière, Line ^b   Laroche, Line ^b   Benedetto, Alexandre ^b   Martel, Dominic ^b   Lapointe, Jean Martin ^d   Ryffel, Bernhard ^c   Malo, Danielle ^a,b  

^a MCGILL UNIVERSITY   (Canada)

^b MONTREAL GENERAL HOSPITAL   (Canada)

^c CNRS   (France)

^d PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; MESSENGER RNA; NATURAL RESISTANCE ASSOCIATED MACROPHAGE PROTEIN 1; PROTEIN; PROTEIN MD 2; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BACTERIAL MEMBRANE; BACTERIAL VIRULENCE; CELL PROLIFERATION; CELLULAR IMMUNITY; CONTROLLED STUDY; CORRELATION ANALYSIS; GENE AMPLIFICATION; GENE OVEREXPRESSION; GENETIC EPISTASIS; HISTOPATHOLOGY; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; INFECTION RESISTANCE; MITOGENESIS; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RETICULOENDOTHELIAL SYSTEM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SALMONELLA TYPHIMURIUM; SALMONELLOSIS; SEPTIC SHOCK; SIGNAL TRANSDUCTION; SPLEEN CELL; SURVIVAL RATE; TRANSGENIC MOUSE; WILD TYPE;

EID: 0038280126     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.170.12.6141     Document Type: Article

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