-
1
-
-
0027026881
-
Molecular genetics of the LDL receptor gene in familial hypercholesterolemia
-
Hobbs HH, Brown MS, Goldstein JL (1992) Molecular genetics of the LDL receptor gene in familial hypercholesterolemia. Hum Mutat 1: 445-446
-
(1992)
Hum Mutat
, vol.1
, pp. 445-446
-
-
Hobbs, H.H.1
Brown, M.S.2
Goldstein, J.L.3
-
3
-
-
0023764622
-
Development of adenovirus vectors for the expression of heterologous genes
-
Berkner KL (1988) Development of adenovirus vectors for the expression of heterologous genes. Biotechniques 6:616-629
-
(1988)
Biotechniques
, vol.6
, pp. 616-629
-
-
Berkner, K.L.1
-
4
-
-
0024311525
-
Helper-free stocks of recombinant adeno-associated viruses: Normal integration does not require viral gene expression
-
Samulski RJ, Chang LS, Shenk T (1989) Helper-free stocks of recombinant adeno-associated viruses: normal integration does not require viral gene expression. J Virol 63:3822-3828
-
(1989)
J Virol
, vol.63
, pp. 3822-3828
-
-
Samulski, R.J.1
Chang, L.S.2
Shenk, T.3
-
5
-
-
0028328261
-
Cellular immunity to viral antigens limits El-deleted adenoviruses for gene therapy
-
Yang Y, Nunes FA, Berencsi K, Furth EE, Gonczol E, Wilson JM (1994) Cellular immunity to viral antigens limits El-deleted adenoviruses for gene therapy. Proc Natl Acad Sci USA 91:4407-4411
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 4407-4411
-
-
Yang, Y.1
Nunes, F.A.2
Berencsi, K.3
Furth, E.E.4
Gonczol, E.5
Wilson, J.M.6
-
6
-
-
0028484704
-
MHC class I-restricted cytotoxic T lymphocytes to viral antigens destroy hepatocytes in mice infected with El-deleted recombinant adenoviruses
-
Yang Y, Ertl HC, Wilson JM (1994) MHC class I-restricted cytotoxic T lymphocytes to viral antigens destroy hepatocytes in mice infected with El-deleted recombinant adenoviruses. Immunity 1: 433-442
-
(1994)
Immunity
, vol.1
, pp. 433-442
-
-
Yang, Y.1
Ertl, H.C.2
Wilson, J.M.3
-
7
-
-
0028246338
-
Ablation of E2A in recombinant adenoviruses improves transgene persistence and decreases inflammatory response in mouse liver
-
Engelhardt JF, Ye X, Doranz B, Wilson JM (1994) Ablation of E2A in recombinant adenoviruses improves transgene persistence and decreases inflammatory response in mouse liver. Proc Natl Acad Sci USA 91:6196-6200
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 6196-6200
-
-
Engelhardt, J.F.1
Ye, X.2
Doranz, B.3
Wilson, J.M.4
-
8
-
-
0030042794
-
Prolonged metabolic correction in adult ornithine transcarbamylase-deficient mice with adenoviral vectors
-
Ye X, Robinson M, Batshaw M, Furth E, Smith I, Wilson JM (1996) Prolonged metabolic correction in adult ornithine transcarbamylase-deficient mice with adenoviral vectors. J Biol Chem 271: 3639-3646
-
(1996)
J Biol Chem
, vol.271
, pp. 3639-3646
-
-
Ye, X.1
Robinson, M.2
Batshaw, M.3
Furth, E.4
Smith, I.5
Wilson, J.M.6
-
9
-
-
0030857810
-
Liver-directed gene transfer and prolonged expression of three major human apoE isoforms in apoE-deficient Mice
-
Tsukamoto K, Smith P, Glick JM, Rader D (1997) Liver-directed gene transfer and prolonged expression of three major human apoE isoforms in apoE-deficient Mice. J Clin Invest 100: 107-114
-
(1997)
J Clin Invest
, vol.100
, pp. 107-114
-
-
Tsukamoto, K.1
Smith, P.2
Glick, J.M.3
Rader, D.4
-
10
-
-
0032830257
-
Rapid regression of atherosclerosis induced by liver-directed gene transfer of apolipoprotein E in apoE deficient mice
-
Tsukamoto K, Tangirala R, Chun SH, Puré E, Rader DJ (1999) Rapid regression of atherosclerosis induced by liver-directed gene transfer of apolipoprotein E in apoE deficient mice. Arterioscler Thromb Vase Biol 19: 2162-2170
-
(1999)
Arterioscler Thromb Vase Biol
, vol.19
, pp. 2162-2170
-
-
Tsukamoto, K.1
Tangirala, R.2
Chun, S.H.3
Puré, E.4
Rader, D.J.5
-
11
-
-
0032706442
-
Regression of atherosclerosis induced by liver-directed gene transfer of apolipoprotein A-I in mice
-
Tangirala RK, Tsukamoto K, Chun SH, Usher D, Puré E, Rader DJ (1999) Regression of atherosclerosis induced by liver-directed gene transfer of apolipoprotein A-I in mice. Circulation 100: 1816-1822
-
(1999)
Circulation
, vol.100
, pp. 1816-1822
-
-
Tangirala, R.K.1
Tsukamoto, K.2
Chun, S.H.3
Usher, D.4
Puré, E.5
Rader, D.J.6
-
12
-
-
0029959867
-
Biology of adenovirus vectors with E1 and E4 deletions for liver-directed gene therapy
-
Gao GP, Yang Y, Wilson JM (1996) Biology of adenovirus vectors with E1 and E4 deletions for liver-directed gene therapy. J Virol 70: 8934-8943
-
(1996)
J Virol
, vol.70
, pp. 8934-8943
-
-
Gao, G.P.1
Yang, Y.2
Wilson, J.M.3
-
13
-
-
0032549625
-
Selective gene transfer into the liver of non-human primates with El-deleted, E2A-defective, or E1-E4 deleted recombinant adenoviruses
-
Raper SE, Haskal ZJ, Ye X, Pugh C, Furth EE, Gao GP, Wilson JM (1998) Selective gene transfer into the liver of non-human primates with El-deleted, E2A-defective, or E1-E4 deleted recombinant adenoviruses. Hum Gene Ther 9:671-679
-
(1998)
Hum Gene Ther
, vol.9
, pp. 671-679
-
-
Raper, S.E.1
Haskal, Z.J.2
Ye, X.3
Pugh, C.4
Furth, E.E.5
Gao, G.P.6
Wilson, J.M.7
-
14
-
-
0033588888
-
Recombinant adenovirus gene transfer in adults with partial ornithine transcarbamylase deficiency (OTCD)
-
Batshaw ML, Wilson JM, Raper S, Yudkoff M, Robinson MB (1999) Recombinant adenovirus gene transfer in adults with partial ornithine transcarbamylase deficiency (OTCD). Hum Gene Ther 10: 2419-2437
-
(1999)
Hum Gene Ther
, vol.10
, pp. 2419-2437
-
-
Batshaw, M.L.1
Wilson, J.M.2
Raper, S.3
Yudkoff, M.4
Robinson, M.B.5
-
15
-
-
0034989793
-
A death in the laboratory: The politics of the Gelsinger aftermath
-
Carmen IH (2001) A death in the laboratory: the politics of the Gelsinger aftermath. Mol Ther 3: 425-428
-
(2001)
Mol Ther
, vol.3
, pp. 425-428
-
-
Carmen, I.H.1
-
16
-
-
0030462599
-
A helper-dependent adenovirus vector system: Removal of helper virus by Cre-mediated excision of the viral packaging signal
-
Parks RJ, Chen L, Anton M, Sankar U, Rudnicki MA, Graham FL (1996) A helper-dependent adenovirus vector system: removal of helper virus by Cre-mediated excision of the viral packaging signal. Proc Natl Acad Sci USA 93: 13565-13570
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 13565-13570
-
-
Parks, R.J.1
Chen, L.2
Anton, M.3
Sankar, U.4
Rudnicki, M.A.5
Graham, F.L.6
-
17
-
-
0029966514
-
Recombinant adenovirus deleted of all viral genes for gene therapy of cystic fibrosis
-
Fisher K, Choi H, Burda J, Chen S, Wilson JM (1996) Recombinant adenovirus deleted of all viral genes for gene therapy of cystic fibrosis. Virology 217: 11-22
-
(1996)
Virology
, vol.217
, pp. 11-22
-
-
Fisher, K.1
Choi, H.2
Burda, J.3
Chen, S.4
Wilson, J.M.5
-
18
-
-
0029962474
-
In vivo expression of full-length dystrophin from adenoviral vectors deleted of all viral genes
-
Haecker S, Stedman H, Balice-Gordon R, Smith D, Greelish J, Mitchell M, Wells A, Sweeney L, Wilson JM (1996) In vivo expression of full-length dystrophin from adenoviral vectors deleted of all viral genes. Hum Gene Ther 7: 1907-1914
-
(1996)
Hum Gene Ther
, vol.7
, pp. 1907-1914
-
-
Haecker, S.1
Stedman, H.2
Balice-Gordon, R.3
Smith, D.4
Greelish, J.5
Mitchell, M.6
Wells, A.7
Sweeney, L.8
Wilson, J.M.9
-
19
-
-
0031049699
-
Persistence in muscle of an adenoviral vector that lacks all viral genes
-
Chen H, Mack L, Kelly R, Ontell M, Kochanek S, Clemens P (1997) Persistence in muscle of an adenoviral vector that lacks all viral genes. Proc Natl Acad Sci USA 94: 1645-1650
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 1645-1650
-
-
Chen, H.1
Mack, L.2
Kelly, R.3
Ontell, M.4
Kochanek, S.5
Clemens, P.6
-
20
-
-
0031916435
-
Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity
-
Schiedner G, Morral N, Parks RJ, Wu Y, Koopmans SC, Langston C, Graham FL, Beaudet AL, Kochanek S (1998) Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity. Nat Genet 18: 180-183
-
(1998)
Nat Genet
, vol.18
, pp. 180-183
-
-
Schiedner, G.1
Morral, N.2
Parks, R.J.3
Wu, Y.4
Koopmans, S.C.5
Langston, C.6
Graham, F.L.7
Beaudet, A.L.8
Kochanek, S.9
-
21
-
-
13144283616
-
An adenoviral vector deleted for all viral coding sequences results in enhanced safety and extended expression of a leptin transgene
-
Morsy MA, Gu M, Motzel S, Zhao J, Lin J, Su Q, Allen H, Franlin L, Parks RJ, Graham FL, Kochanek S, Bett AJ, Caskey CT (1998) An adenoviral vector deleted for all viral coding sequences results in enhanced safety and extended expression of a leptin transgene. Proc Natl Acad Sci USA 95: 7866-7871
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 7866-7871
-
-
Morsy, M.A.1
Gu, M.2
Motzel, S.3
Zhao, J.4
Lin, J.5
Su, Q.6
Allen, H.7
Franlin, L.8
Parks, R.J.9
Graham, F.L.10
Kochanek, S.11
Bett, A.J.12
Caskey, C.T.13
-
22
-
-
12944315064
-
Optimization of the helper-dependent adenovirus system for production and potency in vivo
-
Sandig V, Youil R, Bett AJ, Franlin LL, Oshima M, Maione D, Wang F, Metzker ML, Savino R, Caskey CT (2000) Optimization of the helper-dependent adenovirus system for production and potency in vivo. Proc Natl Acad Sci USA 97: 1002-1007
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 1002-1007
-
-
Sandig, V.1
Youil, R.2
Bett, A.J.3
Franlin, L.L.4
Oshima, M.5
Maione, D.6
Wang, F.7
Metzker, M.L.8
Savino, R.9
Caskey, C.T.10
-
23
-
-
0035814955
-
Long-term stable correction of low-density lipoprotein receptor-deficient mice with a helper-dependent adenoviral vector expressing the very low-density lipoprotein receptor
-
Oka K, Pastore L, Kim IH, Merched A, Nomura S, Lee HJ, Merched-Sauvage M, Arden-Riley C, Lee B, Finegold M, Beaudet A, Chan L (2001) Long-term stable correction of low-density lipoprotein receptor-deficient mice with a helper-dependent adenoviral vector expressing the very low-density lipoprotein receptor. Circulation 103: 1274-1281
-
(2001)
Circulation
, vol.103
, pp. 1274-1281
-
-
Oka, K.1
Pastore, L.2
Kim, I.H.3
Merched, A.4
Nomura, S.5
Lee, H.J.6
Merched-Sauvage, M.7
Arden-Riley, C.8
Lee, B.9
Finegold, M.10
Beaudet, A.11
Chan, L.12
-
24
-
-
0028170362
-
Prospects for the use of adeno-associated virus as a vector for human gene therapy
-
Kotin RM (1994) Prospects for the use of adeno-associated virus as a vector for human gene therapy. Hum Gene Ther 5: 793-801
-
(1994)
Hum Gene Ther
, vol.5
, pp. 793-801
-
-
Kotin, R.M.1
-
25
-
-
0031019819
-
Persistent expression of human clotting factor IX from mouse liver after intravenous injection of adeno-associated virus vectors
-
Koeberl D, Alexander I, Halbert C, Russell D, Miller AD (1997) Persistent expression of human clotting factor IX from mouse liver after intravenous injection of adeno-associated virus vectors. Proc Natl Acad Sci USA 94: 1426-1431
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 1426-1431
-
-
Koeberl, D.1
Alexander, I.2
Halbert, C.3
Russell, D.4
Miller, A.D.5
-
26
-
-
0031775494
-
Adeno-associated virus as a vector for liver-directed gene therapy
-
Xiao W, Berta SC, Lu MM, Moscioni AD, Tazelaar J, Wilson JM (1998) Adeno-associated virus as a vector for liver-directed gene therapy. J Virol 72: 10222-10226
-
(1998)
J Virol
, vol.72
, pp. 10222-10226
-
-
Xiao, W.1
Berta, S.C.2
Lu, M.M.3
Moscioni, A.D.4
Tazelaar, J.5
Wilson, J.M.6
-
27
-
-
0030997346
-
Persistent and therapeutic concentrations of human factor IX in mice after hepatic gene transfer of recombinant AAV vectors
-
Snyder RO, Miao CH, Patijn GA, Spratt SK, Danos O, Nagy D, Gown AM, Winther B, Meuse L, Cohen LK, Thompson AR, Kay MA (1997) Persistent and therapeutic concentrations of human factor IX in mice after hepatic gene transfer of recombinant AAV vectors. Nat Genet 16: 270-276
-
(1997)
Nat Genet
, vol.16
, pp. 270-276
-
-
Snyder, R.O.1
Miao, C.H.2
Patijn, G.A.3
Spratt, S.K.4
Danos, O.5
Nagy, D.6
Gown, A.M.7
Winther, B.8
Meuse, L.9
Cohen, L.K.10
Thompson, A.R.11
Kay, M.A.12
-
28
-
-
0034137797
-
Sustained expression of therapeutic level of factor IX in hemophilia B dogs by AAV-mediated gene therapy in liver
-
Wang L, Nichols TC, Read MS, Bellinger DA, Verma IM (2000) Sustained expression of therapeutic level of factor IX in hemophilia B dogs by AAV-mediated gene therapy in liver. Mol Ther 1: 154-158
-
(2000)
Mol Ther
, vol.1
, pp. 154-158
-
-
Wang, L.1
Nichols, T.C.2
Read, M.S.3
Bellinger, D.A.4
Verma, I.M.5
-
29
-
-
17444372024
-
Correction of hemophilia B in canine and murine models using recombinant adeno-associated viral vectors
-
Snyder RO, Miao C, Meuse L, Tubb J, Donahue BA, Lin HF, Stafford DW, Patel S, Thompson AR, Nichols T, Read MS, Bellinger DA, Brinkhous KM, Kay MA (1999) Correction of hemophilia B in canine and murine models using recombinant adeno-associated viral vectors. Nat Med 5: 64-70
-
(1999)
Nat Med
, vol.5
, pp. 64-70
-
-
Snyder, R.O.1
Miao, C.2
Meuse, L.3
Tubb, J.4
Donahue, B.A.5
Lin, H.F.6
Stafford, D.W.7
Patel, S.8
Thompson, A.R.9
Nichols, T.10
Read, M.S.11
Bellinger, D.A.12
Brinkhous, K.M.13
Kay, M.A.14
-
30
-
-
0034161486
-
Sustained expression of human factor VIII in mice using a parvovirus-based vector
-
Chao H, Mao L, Bruce AT, Walsh CE (2000) Sustained expression of human factor VIII in mice using a parvovirus-based vector. Blood 95: 1594-1599
-
(2000)
Blood
, vol.95
, pp. 1594-1599
-
-
Chao, H.1
Mao, L.2
Bruce, A.T.3
Walsh, C.E.4
-
31
-
-
0034264614
-
Prolonged correction of hyperlipidemia in mice with familial hypercholesterolemia using an adeno-associated viral vector expressing very-low-density lipoprotein receptor
-
Chen SJ, Rader DJ, Tazelaar J, Kawashiri M, Gao G, Wilson JM (2000) Prolonged correction of hyperlipidemia in mice with familial hypercholesterolemia using an adeno-associated viral vector expressing very-low-density lipoprotein receptor. Mol Ther 2: 256-261
-
(2000)
Mol Ther
, vol.2
, pp. 256-261
-
-
Chen, S.J.1
Rader, D.J.2
Tazelaar, J.3
Kawashiri, M.4
Gao, G.5
Wilson, J.M.6
-
32
-
-
0029147628
-
Nonviral gene therapy: The promise of genes as pharmaceutical products
-
Ledley F (1996) Nonviral gene therapy: the promise of genes as pharmaceutical products. Hum Gene Ther 6: 1129-1144
-
(1996)
Hum Gene Ther
, vol.6
, pp. 1129-1144
-
-
Ledley, F.1
-
33
-
-
0027313072
-
Systemic gene expression after intravenous DNA delivery into adult mice
-
Zhu N, Liggitt D, Debs R (1993) Systemic gene expression after intravenous DNA delivery into adult mice. Science 261: 209-211
-
(1993)
Science
, vol.261
, pp. 209-211
-
-
Zhu, N.1
Liggitt, D.2
Debs, R.3
-
34
-
-
0026315433
-
Receptor-mediated gene delivery in vivo. Partial correction of genetic analbuminemia in nagase rats
-
Wu G, Wilson JM, Shalaby F, Grossman M, Shafritz D, Wu C (1991) Receptor-mediated gene delivery in vivo. Partial correction of genetic analbuminemia in nagase rats. J Biol Chem 266: 14338-14342
-
(1991)
J Biol Chem
, vol.266
, pp. 14338-14342
-
-
Wu, G.1
Wilson, J.M.2
Shalaby, F.3
Grossman, M.4
Shafritz, D.5
Wu, C.6
-
35
-
-
0031795974
-
Liver-directed gene transfer: A linear polyethlenimine derivative mediates highly efficient DNA delivery to primary hepatocytes in vitro and in vivo
-
Chemin I, Moradpour D, Wieland S, Offensperger WB, Walter E, Behr JP, Blum HE (1998) Liver-directed gene transfer: a linear polyethlenimine derivative mediates highly efficient DNA delivery to primary hepatocytes in vitro and in vivo. J Viral Hepat 5: 369-375
-
(1998)
J Viral Hepat
, vol.5
, pp. 369-375
-
-
Chemin, I.1
Moradpour, D.2
Wieland, S.3
Offensperger, W.B.4
Walter, E.5
Behr, J.P.6
Blum, H.E.7
-
36
-
-
0028464351
-
Strategies to achieve targeted gene delivery via the receptor-mediated endocytosis pathway
-
Michael S, Curiel DT (1994) Strategies to achieve targeted gene delivery via the receptor-mediated endocytosis pathway. Gene Ther 1: 223-232
-
(1994)
Gene Ther
, vol.1
, pp. 223-232
-
-
Michael, S.1
Curiel, D.T.2
-
37
-
-
0032578532
-
Site-specific gene delivery in vivo through engineered Sendai viral envelopes
-
Ramani K, Hassan Q, Venkaiah B, Hasnain SE, Sarkar DP (1998) Site-specific gene delivery in vivo through engineered Sendai viral envelopes. Proc Natl Acad Sci USA 95: 11886-11890
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 11886-11890
-
-
Ramani, K.1
Hassan, Q.2
Venkaiah, B.3
Hasnain, S.E.4
Sarkar, D.P.5
-
38
-
-
0026687453
-
Coupling of adenovirus to transferrin-polylysine/DNA complexes greatly enhances receptor-mediated gene delivery and expression of transfected genes
-
Wagner E, Zatloukal K, Cotten M, Kirlappos H, Mechtler K, Curiel DT, Birnstiel ML (1992) Coupling of adenovirus to transferrin-polylysine/DNA complexes greatly enhances receptor-mediated gene delivery and expression of transfected genes. Proc Natl Acad Sci USA 89: 6099-6103
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 6099-6103
-
-
Wagner, E.1
Zatloukal, K.2
Cotten, M.3
Kirlappos, H.4
Mechtler, K.5
Curiel, D.T.6
Birnstiel, M.L.7
|