Stable correction of a genetic deficiency in human cells by an episome carrying a 115 kb genomic transgene

Nature Biotechnology

Volumn 18, Issue 12, 2000, Pages 1311-1314

  Wade Martins, Richard ^a,b   White, Robert E ^a   Kimura, Hiroshi ^c   Cook, Peter R ^c   James, Michael R ^a,d  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE;

ARTICLE; CHROMOSOME; EPISOME; EPSTEIN BARR VIRUS; GENE EXPRESSION; GENE LOCUS; GENE SILENCING; GENETIC DISORDER; HUMAN; HUMAN CELL; MOLECULAR CLONING; PRIORITY JOURNAL; PROMOTER REGION; SILENCER GENE; TRANSGENE;

CELL LINE; CHROMOSOMES, ARTIFICIAL, BACTERIAL; FIBROBLASTS; GENE EXPRESSION; GENE THERAPY; GENETIC VECTORS; HUMANS; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; IN SITU HYBRIDIZATION, FLUORESCENCE; LESCH-NYHAN SYNDROME; MALE; PLASMIDS; TRANSFECTION; TRANSFORMATION, GENETIC; TRANSGENES;

BACTERIA (MICROORGANISMS); HUMAN HERPESVIRUS 4; MAMMALIA;

EID: 0033669478     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/82444     Document Type: Article

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