메뉴 건너뛰기




Volumn 52, Issue 3, 2003, Pages 313-325

Ultrastructural basis for the transition of cell death mode from apoptosis to necrosis in menadione-treated osteosarcoma 143B cells

Author keywords

Apoptosis; Cell death mode; Electron microscopy; Flow cytometry; Menadione; Necrosis

Indexed keywords

ANTIFIBRINOLYTIC AGENT; MENADIONE;

EID: 0038115134     PISSN: 00220744     EISSN: None     Source Type: Journal    
DOI: 10.1093/jmicro/52.3.313     Document Type: Article
Times cited : (20)

References (66)
  • 1
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
    • Kerr J F, Wyllie H A, and Currie A R (1972) Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br. J. Cancer 26: 239-257.
    • (1972) Br. J. Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.1    Wyllie, H.A.2    Currie, A.R.3
  • 2
    • 0018830636 scopus 로고
    • Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation
    • Wyllie A H (1980) Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature 284: 555-556.
    • (1980) Nature , vol.284 , pp. 555-556
    • Wyllie, A.H.1
  • 4
    • 0030580287 scopus 로고    scopus 로고
    • Why are mitochondria involved in apoptosis? Permeability transition pores and apoptosis as selective mechanisms to eliminate superoxide-producing mitochondria and cell
    • Skulachev V P (1996) why are mitochondria involved in apoptosis? Permeability transition pores and apoptosis as selective mechanisms to eliminate superoxide-producing mitochondria and cell. FEBS Lett. 397: 7-10.
    • (1996) FEBS Lett. , vol.397 , pp. 7-10
    • Skulachev, V.P.1
  • 5
    • 0034641918 scopus 로고    scopus 로고
    • The biochemistry of apoptosis
    • Hengartner M O (2000) The biochemistry of apoptosis. Nature 407: 770-776.
    • (2000) Nature , vol.407 , pp. 770-776
    • Hengartner, M.O.1
  • 7
    • 0036479012 scopus 로고    scopus 로고
    • Apoptosis-inducing factor (AIF): A novel caspase-independent death effector released from mitochondria
    • Cande C, Cohen I, Dougas E, Ravagnan L, Larochette N, Zamzami N, and Kroemer G (2002) Apoptosis-inducing factor (AIF): a novel caspase-independent death effector released from mitochondria. Biochemie 84: 215-222.
    • (2002) Biochemie , vol.84 , pp. 215-222
    • Cande, C.1    Cohen, I.2    Dougas, E.3    Ravagnan, L.4    Larochette, N.5    Zamzami, N.6    Kroemer, G.7
  • 8
    • 0032515339 scopus 로고    scopus 로고
    • Apoptosis in the absence of cytochrome c accumulation in the cytosol
    • Tang D G, Zhenyu L L, and Joshi B (1998) Apoptosis in the absence of cytochrome c accumulation in the cytosol. Biochem. Biophys. Res. Commun. 242: 380-384.
    • (1998) Biochem. Biophys. Res. Commun. , vol.242 , pp. 380-384
    • Tang, D.G.1    Zhenyu, L.L.2    Joshi, B.3
  • 9
    • 0033593791 scopus 로고    scopus 로고
    • Altered cytochrome c display proceeds apoptotic cell death in Drosophila
    • Varkey J, Chen P, Jemmerson R, and Abram J M (1999) Altered cytochrome c display proceeds apoptotic cell death in Drosophila. J. Cell Biol. 144: 701-710.
    • (1999) J. Cell Biol. , vol.144 , pp. 701-710
    • Varkey, J.1    Chen, P.2    Jemmerson, R.3    Abram, J.M.4
  • 11
    • 0031037897 scopus 로고    scopus 로고
    • The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis
    • Luck R M, Bossy-Wetzel E, Green D R, and Newmeyer D D (1997) The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science 275: 1132-1136.
    • (1997) Science , vol.275 , pp. 1132-1136
    • Luck, R.M.1    Bossy-Wetzel, E.2    Green, D.R.3    Newmeyer, D.D.4
  • 12
    • 0033805296 scopus 로고    scopus 로고
    • Triggering and modulation of apoptosis by oxidative stress
    • Chandra J, Sanali A, and Orrenius S (2000) Triggering and modulation of apoptosis by oxidative stress. Free Radic. Biol. Med. 29: 323-332.
    • (2000) Free Radic. Biol. Med. , vol.29 , pp. 323-332
    • Chandra, J.1    Sanali, A.2    Orrenius, S.3
  • 14
    • 0024401864 scopus 로고
    • Apoptosis. The mechanism of cell death in dimethylnitrosamine-induced hepatotoxicity
    • Pritchard D J and Butler W H (1989) Apoptosis. The mechanism of cell death in dimethylnitrosamine-induced hepatotoxicity. J. Pathol. 158: 253-260.
    • (1989) J. Pathol. , vol.158 , pp. 253-260
    • Pritchard, D.J.1    Butler, W.H.2
  • 16
    • 0027768576 scopus 로고
    • Demonstration of extensive chromatin cleavage in transplanted Morris hepatoma 777 tissue: Apoptosis or necrosis?
    • Fukuda K, Kojiro M, and Chin J-F (1993) Demonstration of extensive chromatin cleavage in transplanted Morris hepatoma 777 tissue: apoptosis or necrosis? Am. J. Pathol. 142: 935-946.
    • (1993) Am. J. Pathol. , vol.142 , pp. 935-946
    • Fukuda, K.1    Kojiro, M.2    Chin, J.-F.3
  • 17
    • 0031813589 scopus 로고    scopus 로고
    • Oxidative stress induces a form of programmed cell death with characteristics of both apoptosis and necrosis in neuronal cells
    • Tan S, Wood M, and Mahr P (1998) Oxidative stress induces a form of programmed cell death with characteristics of both apoptosis and necrosis in neuronal cells. J. Neurochem. 71: 95-105.
    • (1998) J. Neurochem. , vol.71 , pp. 95-105
    • Tan, S.1    Wood, M.2    Mahr, P.3
  • 18
    • 0025880971 scopus 로고
    • Drug-target interactions: Only the first step in the commitment to a programmed cell death?
    • Dive C and Hickman J A (1991) Drug-target interactions: only the first step in the commitment to a programmed cell death? Brit. J. Cancer 64: 192-196.
    • (1991) Brit. J. Cancer , vol.64 , pp. 192-196
    • Dive, C.1    Hickman, J.A.2
  • 19
    • 0025732732 scopus 로고
    • Dose-dependent induction of apoptosis in human tumour cell lines by widely diverging stimuli
    • Lennon S V, Martin S J, and Cotter J G (1991) Dose-dependent induction of apoptosis in human tumour cell lines by widely diverging stimuli. Cell Prolif. 24: 203-214.
    • (1991) Cell Prolif. , vol.24 , pp. 203-214
    • Lennon S. V1    Martin, S.J.2    Cotter, J.G.3
  • 20
    • 0029881461 scopus 로고    scopus 로고
    • Mechanism of death induced by cisplatin in proximal tubular epithelial cells: Apoptosis vs. necrosis
    • Lieberthal W, Triaca V, and Levine J (1996) Mechanism of death induced by cisplatin in proximal tubular epithelial cells: apoptosis vs. necrosis. Am. J. Physiol. 270: F700-F708.
    • (1996) Am. J. Physiol. , vol.270
    • Lieberthal, W.1    Triaca, V.2    Levine, J.3
  • 21
    • 0028821452 scopus 로고
    • The pharmacology of T cell apoptosis
    • Kroemer G (1995) The pharmacology of T cell apoptosis. Adv. Immunol. 58: 211-296.
    • (1995) Adv. Immunol. , vol.58 , pp. 211-296
    • Kroemer, G.1
  • 23
    • 0027479977 scopus 로고
    • Apoptosis: The biochemistry and molecular biology of programmed cell death
    • Schwarztman R A and Cidlowski J A (1993) Apoptosis: the biochemistry and molecular biology of programmed cell death. Endocr. Res. 14: 133-151.
    • (1993) Endocr. Res. , vol.14 , pp. 133-151
    • Schwarztman, R.A.1    Cidlowski, J.A.2
  • 25
    • 0023718438 scopus 로고
    • Stimulation of endogenous endonuclease activity in hepatocytes exposed to oxidative stress
    • McConkey D J, Hartzell P, Nicotera P, Wyllie A H, and Orrenius S (1988) Stimulation of endogenous endonuclease activity in hepatocytes exposed to oxidative stress. Toxicol Lett. 42: 123-130.
    • (1988) Toxicol Lett. , vol.42 , pp. 123-130
    • McConkey, D.J.1    Hartzell, P.2    Nicotera, P.3    Wyllie, A.H.4    Orrenius, S.5
  • 26
    • 0028032254 scopus 로고
    • Different prooxidant levels stimulate growth, trigger apoptosis or produce necrosis of insulin-secreting RINm5F cells
    • Dypunkt J M, Ankerona M, Burkitt M, SjöSholm Å, Ström K, Orrenius S, and Nicotera P (1994) Different prooxidant levels stimulate growth, trigger apoptosis or produce necrosis of insulin-secreting RINm5F cells. J. Biol. Chem. 269: 30553-30560.
    • (1994) J. Biol. Chem. , vol.269 , pp. 30553-30560
    • Dypunkt, J.M.1    Ankerona, M.2    Burkitt, M.3    SjöSholm, Å.4    Ström, K.5    Orrenius, S.6    Nicotera, P.7
  • 28
    • 0033524857 scopus 로고    scopus 로고
    • A comparative study of apoptosis and necrosis in HepG2 cells: Oxidant-induced caspase inactivation leads to necrosis
    • Samail A, Nordgren H, Zhivotovsky B, Peterson E, and Orrenius S (1999) A comparative study of apoptosis and necrosis in HepG2 cells: oxidant-induced caspase inactivation leads to necrosis. Biochem. Biophys. Res. Commun. 255: 6-11.
    • (1999) Biochem. Biophys. Res. Commun. , vol.255 , pp. 6-11
    • Samail, A.1    Nordgren, H.2    Zhivotovsky, B.3    Peterson, E.4    Orrenius, S.5
  • 30
    • 0028800947 scopus 로고
    • Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus - Inhibition by overexpression of Bcl-2 and Abl
    • Martin S J, Reutelingsperger C P M, McGahon A J, Rader J A, Vanschie R, Laface D M, and Green D R (1995) Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus - inhibition by overexpression of Bcl-2 and Abl. J. Exp. Med. 182: 1545-1556.
    • (1995) J. Exp. Med. , vol.182 , pp. 1545-1556
    • Martin, S.J.1    Reutelingsperger, C.P.M.2    McGahon, A.J.3    Rader, J.A.4    Vanschie, R.5    Laface, D.M.6    Green, D.R.7
  • 31
    • 0020384216 scopus 로고
    • A stable propidium iodide staining procedure for flow cytometry
    • Deitch A D, Law H, and White R D (1982) A stable propidium iodide staining procedure for flow cytometry. J. Histochem. Cytochem. 30: 967-972.
    • (1982) J. Histochem. Cytochem. , vol.30 , pp. 967-972
    • Deitch, A.D.1    Law, H.2    White, R.D.3
  • 32
    • 0035127509 scopus 로고    scopus 로고
    • Opposite effects of microtubule-stabilizing and microtubule-destabilizing drugs on biogenesis of mitochondria in mammalian cells
    • Karbowski M, Spodnik J H, Teranishi M, Wozniak M, Nishizawa Y, Usukura J, and Wakabayashi T (2001) Opposite effects of microtubule-stabilizing and microtubule-destabilizing drugs on biogenesis of mitochondria in mammalian cells. J. Cell Sci. 114: 281-291.
    • (2001) J. Cell Sci. , vol.114 , pp. 281-291
    • Karbowski, M.1    Spodnik, J.H.2    Teranishi, M.3    Wozniak, M.4    Nishizawa, Y.5    Usukura, J.6    Wakabayashi, T.7
  • 33
    • 0008060872 scopus 로고    scopus 로고
    • Induction of megamitochondria by some chemicals inducing oxidative stress in primary cultured rat hepatocytes
    • Karbowski M, Kurono C, Nishizawa Y, Soji T, and Wakabayashi T (1997) Induction of megamitochondria by some chemicals inducing oxidative stress in primary cultured rat hepatocytes. Biochim. Biophys. Acta 1349: 242-250.
    • (1997) Biochim. Biophys. Acta , vol.1349 , pp. 242-250
    • Karbowski, M.1    Kurono, C.2    Nishizawa, Y.3    Soji, T.4    Wakabayashi, T.5
  • 34
    • 0030915587 scopus 로고    scopus 로고
    • Intracellular levels of ATP determine cell death fate by apoptosis or necrosis
    • Eguchi Y, Shimizu S, and Tsujimoto Y (1997) Intracellular levels of ATP determine cell death fate by apoptosis or necrosis. Cancer Res. 57: 1835-1840.
    • (1997) Cancer Res. , vol.57 , pp. 1835-1840
    • Eguchi, Y.1    Shimizu, S.2    Tsujimoto, Y.3
  • 35
    • 0030900980 scopus 로고    scopus 로고
    • Intracellular adenine triphosphate (ATP) concentration: A switch in the decision between apoptosis and necrosis
    • Leist M, Single B, Castoldi A F, Kuhnle S, and Nicotera P (1997) Intracellular adenine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis. J. Exp. Med. 185: 1481-1486.
    • (1997) J. Exp. Med. , vol.185 , pp. 1481-1486
    • Leist, M.1    Single, B.2    Castoldi, A.F.3    Kuhnle, S.4    Nicotera, P.5
  • 36
    • 0032494108 scopus 로고    scopus 로고
    • Differential regulation and ATP requirement for caspase-8 and caspase-3 activation during CD95- and anticancer drug-induced apoptosis
    • Ferrari D, Stepczynska A, Los M, Wesselborg S, and Schulze-Ostoff K (1998) Differential regulation and ATP requirement for caspase-8 and caspase-3 activation during CD95- and anticancer drug-induced apoptosis. J. Exp. Med. 188: 979-984.
    • (1998) J. Exp. Med. , vol.188 , pp. 979-984
    • Ferrari, D.1    Stepczynska, A.2    Los, M.3    Wesselborg, S.4    Schulze-Ostoff, K.5
  • 37
    • 0033598713 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase is a mediator of necrotic cell death
    • Ha H C and Synder S H (1999) Poly(ADP-ribose) polymerase is a mediator of necrotic cell death. Proc. Natl. Acad. Sci. USA 96: 13978-13982.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 13978-13982
    • Ha, H.C.1    Synder, S.H.2
  • 38
    • 0035525733 scopus 로고    scopus 로고
    • Cellular stress response and apoptosis in cancer therapy
    • Herr I and Debatin K-M (2001) Cellular stress response and apoptosis in cancer therapy. Blood 98: 2603-2614.
    • (2001) Blood , vol.98 , pp. 2603-2614
    • Herr, I.1    Debatin, K.-M.2
  • 39
    • 0020440918 scopus 로고
    • The metabolism of menadione (2-methy-1,4-naphthoquinone) by isolated hepatocytes
    • Thor H, Smith M T, Hartzell P, Beilano G, Jewell S, and Orrenius S (1982) The metabolism of menadione (2-methy-1,4-naphthoquinone) by isolated hepatocytes. J. Biol. Chem. 257: 12419-12425.
    • (1982) J. Biol. Chem. , vol.257 , pp. 12419-12425
    • Thor, H.1    Smith, M.T.2    Hartzell, P.3    Beilano, G.4    Jewell, S.5    Orrenius, S.6
  • 41
    • 0029153913 scopus 로고
    • Apoptosis and necrosis: Two distinct events, induced, respectively by mild and intense insult with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell culture
    • Bonfoco B, Krainc D, Ankarcrona M, Nicotera P, and Lipton S A (1995) Apoptosis and necrosis: two distinct events, induced, respectively by mild and intense insult with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell culture. Proc. Natl. Acad. Sci. USA 97: 7162-7166.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 7162-7166
    • Bonfoco, B.1    Krainc, D.2    Ankarcrona, M.3    Nicotera, P.4    Lipton, S.A.5
  • 42
    • 0343376119 scopus 로고    scopus 로고
    • Mechanism of dithicarbamate inhibition of apoptosis: Thiol oxidation by dithicarbamate disulfides directly inhibits processing of the caspase-3 proenzyme
    • Nobel C S, Burgess D H, Zhivotovsky B, Burkitt M J, Orrenius S, and Slater A F (1997) Mechanism of dithicarbamate inhibition of apoptosis: thiol oxidation by dithicarbamate disulfides directly inhibits processing of the caspase-3 proenzyme. Chem. Res. Toxicol. 10: 636-643.
    • (1997) Chem. Res. Toxicol. , vol.10 , pp. 636-643
    • Nobel, C.S.1    Burgess, D.H.2    Zhivotovsky, B.3    Burkitt, M.J.4    Orrenius, S.5    Slater, A.F.6
  • 43
    • 0030865646 scopus 로고    scopus 로고
    • Dual regulation of caspase activity by hydrogen peroxide; implications for apoptosis
    • Hampton M B and Orrenius S (1997) Dual regulation of caspase activity by hydrogen peroxide; implications for apoptosis. FEBS Lett. 414: 552-556.
    • (1997) FEBS Lett. , vol.414 , pp. 552-556
    • Hampton, M.B.1    Orrenius, S.2
  • 45
    • 0032571567 scopus 로고    scopus 로고
    • Inhibition of caspase activity induces a switch from apoptosis to necrosis
    • Lemaire C, Andreau K, Souvannavong V, and Adam A (1998) Inhibition of caspase activity induces a switch from apoptosis to necrosis. FEBS Lett. 425: 266-270.
    • (1998) FEBS Lett. , vol.425 , pp. 266-270
    • Lemaire, C.1    Andreau, K.2    Souvannavong, V.3    Adam, A.4
  • 46
    • 0033524857 scopus 로고    scopus 로고
    • A comparative study of apoptosis and necrosis in HepG2 cells: Oxidant-Induced caspase inactivation leads to necrosis
    • Samali A, Nordgren H, Zhivotovsky B, Peterson E, and Orrenius S (1999) A comparative study of apoptosis and necrosis in HepG2 cells: oxidant-induced caspase inactivation leads to necrosis. Biochem. Biophys. Res. Commun. 255: 6-11.
    • (1999) Biochem. Biophys. Res. Commun. , vol.255 , pp. 6-11
    • Samali, A.1    Nordgren, H.2    Zhivotovsky, B.3    Peterson, E.4    Orrenius, S.5
  • 47
    • 0027516607 scopus 로고
    • 3 on human tumor cells by two (MTT and SRB) cell viability assays
    • 3 on human tumor cells by two (MTT and SRB) cell viability assays. Life Sci. 52: 1797-1804.
    • (1993) Life Sci. , vol.52 , pp. 1797-1804
    • Wu, F.Y.-H.1    Liao, W.-C.2    Chang, H.-M.3
  • 52
    • 0027214305 scopus 로고
    • Apoptosis: A product of programmed and un-programmed cell death
    • Eastman A (1993) Apoptosis: a product of programmed and un-programmed cell death. Toxicol. Appl. Pharmacol. 121: 160-164.
    • (1993) Toxicol. Appl. Pharmacol. , vol.121 , pp. 160-164
    • Eastman, A.1
  • 53
    • 0004878698 scopus 로고
    • The pathogenesis of subcellular reaction to lethal injury
    • eds Bajusz E and Jasmin G. Karger, Basel
    • Trump B F and Ginn F L (1969) The pathogenesis of subcellular reaction to lethal injury. In: Methods and Achievements in Experimental Pathology, vol. IV, eds Bajusz E and Jasmin G, pp. 1-29, (Karger, Basel).
    • (1969) Methods and Achievements in Experimental Pathology , vol.4 , pp. 1-29
    • Trump, B.F.1    Ginn, F.L.2
  • 54
    • 0006071994 scopus 로고
    • The role of energy metabolism, ion, and water shift in the pathogenesis of cell injury
    • eds Richter G W and Scarpelli D G. Williams & Wilkins, Baltimore
    • Trump B F, Croker B P, Jr, and Hergner W J (1971) The role of energy metabolism, ion, and water shift in the pathogenesis of cell injury. In: Cell Membranes: Biological and Pathological Aspects, eds Richter G W and Scarpelli D G, pp. 84-128, (Williams & Wilkins, Baltimore).
    • (1971) Cell Membranes: Biological and Pathological Aspects , pp. 84-128
    • Trump, B.F.1    Croker B.P., Jr.2    Hergner, W.J.3
  • 55
    • 85072164911 scopus 로고
    • Cellular and molecular pathology of reversible and irreversible injury
    • eds Tyson C A and Frazier J M. Academic Press, San Diego
    • Trump B F and Berezesky I K (1994) Cellular and molecular pathology of reversible and irreversible injury In: Methods in Toxicology, vol. IB. In Vitro Toxicity Indicators, eds Tyson C A and Frazier J M, pp. 1-22, (Academic Press, San Diego).
    • (1994) Methods in Toxicology, Vol. IB. In Vitro Toxicity Indicators , vol.1 B , pp. 1-22
    • Trump, B.F.1    Berezesky, I.K.2
  • 56
    • 0028946358 scopus 로고
    • Calcium-mediated cell injury and cell death
    • Trump B F and Berezesky I K (1995) Calcium-mediated cell injury and cell death. FASEB J. 9: 219-228.
    • (1995) FASEB J. , vol.9 , pp. 219-228
    • Trump, B.F.1    Berezesky, I.K.2
  • 57
    • 0002204915 scopus 로고
    • Definition and incidence of apoptosis: And historical perspective
    • eds Tomei L D and Cope F O. Cold Spring Harbor Laboratory Press
    • Kerr J F R and Harmon B V (1991) Definition and incidence of apoptosis: and historical perspective. In: Apoptosis: The Molecular Basis of Cell Death, eds Tomei L D and Cope F O, pp. 5-29, (Cold Spring Harbor Laboratory Press).
    • (1991) Apoptosis: The Molecular Basis of Cell Death , pp. 5-29
    • Kerr, J.F.R.1    Harmon B. V2
  • 58
    • 0004454111 scopus 로고
    • Studies on cell agony and death: An attempt at classification
    • eds de Reuck A V S and Knight J. J & A churchill, London
    • Bessis M (1964) Studies on cell agony and death: an attempt at classification. In: Ciba Foundation Symposium on Cellular Injury, eds de Reuck A V S and Knight J, pp. 287-328, (J & A churchill, London).
    • (1964) Ciba Foundation Symposium on Cellular Injury , pp. 287-328
    • Bessis, M.1
  • 59
    • 0037487286 scopus 로고    scopus 로고
    • Differentiation to an NGF-dependent state and apoptosis following NGF removal both occur asynchronously in cultures of PC12 cells
    • Mills J C, Kim L H, and Pittman R N (1997) Differentiation to an NGF-dependent state and apoptosis following NGF removal both occur asynchronously in cultures of PC12 cells. Exp. Cell Res. 281: 837-845.
    • (1997) Exp. Cell Res. , vol.281 , pp. 837-845
    • Mills, J.C.1    Kim, L.H.2    Pittman, R.N.3
  • 60
    • 0030957458 scopus 로고    scopus 로고
    • Actin is cleaved during constitutive apoptosis
    • Brown S B, Bailey K, and Savill J (1997) Actin is cleaved during constitutive apoptosis. Biochem. J. 333: 233-237.
    • (1997) Biochem. J. , vol.333 , pp. 233-237
    • Brown, S.B.1    Bailey, K.2    Savill, J.3
  • 61
    • 0343581291 scopus 로고    scopus 로고
    • State of actin filaments is changed by anoxia in cultured rat neocortical neurons
    • Friedman J E, Chon E J, and Haddad G G (1998) State of actin filaments is changed by anoxia in cultured rat neocortical neurons. Neuroscience 82: 421-427.
    • (1998) Neuroscience , vol.82 , pp. 421-427
    • Friedman, J.E.1    Chon, E.J.2    Haddad, G.G.3
  • 62
    • 0035264041 scopus 로고    scopus 로고
    • Inhibition of mono-ADP-ribosyltransferase activity during the execution phase of apoptosis prevents apoptotic body formation
    • Lodhi I J, Clift R E, Omann G M, Sweeney J F, McMahon K K, and Hinshaw D B (2001) Inhibition of mono-ADP-ribosyltransferase activity during the execution phase of apoptosis prevents apoptotic body formation. Arch. Biochem. Biophys. 387: 66-77.
    • (2001) Arch. Biochem. Biophys. , vol.387 , pp. 66-77
    • Lodhi, I.J.1    Clift, R.E.2    Omann, G.M.3    Sweeney, J.F.4    McMahon, K.K.5    Hinshaw, D.B.6
  • 63
    • 0033526089 scopus 로고    scopus 로고
    • Inhibition of caspases inhibits the release of apoptotic bodies: Bcl-2 inhibits the initiation of formation of apoptotic bodies in chemotherapeutic agent-induced apoptosis
    • Zhang J, Reedy M C, Hannun YA, and Obeid L M (1999) Inhibition of caspases inhibits the release of apoptotic bodies: Bcl-2 inhibits the initiation of formation of apoptotic bodies in chemotherapeutic agent-induced apoptosis. J. Cell Biol. 145: 99-108.
    • (1999) J. Cell Biol. , vol.145 , pp. 99-108
    • Zhang, J.1    Reedy, M.C.2    Hannun, Y.A.3    Obeid, L.M.4
  • 65
    • 0035210350 scopus 로고    scopus 로고
    • Evidence that oxidative stress-induced apoptosis by menadione involves Fas-dependent and Fas-independent pathway
    • Laux I and Nel A (2001) Evidence that oxidative stress-induced apoptosis by menadione involves Fas-dependent and Fas-independent pathway. Clinical Immunol. 101: 335-344.
    • (2001) Clinical Immunol. , vol.101 , pp. 335-344
    • Laux, I.1    Nel, A.2
  • 66
    • 0031918742 scopus 로고    scopus 로고
    • The mitochondrial death/life regulator in apoptosis and necrosis
    • Kroemer G, Dallaporta B, and Resche-Rigon M (1998) The mitochondrial death/life regulator in apoptosis and necrosis. Ann. Rev. Physiol. 60: 619-642.
    • (1998) Ann. Rev. Physiol. , vol.60 , pp. 619-642
    • Kroemer, G.1    Dallaporta, B.2    Resche-Rigon, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.