Inhibition of caspases inhibits the release of apoptotic bodies: Bcl-2 inhibits the initiation of formation of apoptotic bodies in chemotherapeutic agent-induced apoptosis

Journal of Cell Biology

Volumn 145, Issue 1, 1999, Pages 99-108

  Zhang, Jiandi ^a   Reedy, Mary C ^a   Hannun, Yusuf A ^a   Obeid, Lina M ^a,b  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Apoptosis; Bcl 2; Chemotherapy; Electron microscopy; Lipids

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE; CASPASE INHIBITOR; ETOPOSIDE; LIPID; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BCL 2; TETRAPEPTIDE; TRITIUM; VINCRISTINE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL STRUCTURE; CELL VIABILITY; CHROMATIN CONDENSATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOPATHOLOGY; DRUG MECHANISM; ENZYME DEGRADATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; LIPID TRANSPORT; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CASPASE 1; CASPASE 3; CASPASES; CELL SIZE; CHROMATIN; CYSTEINE PROTEINASE INHIBITORS; ETOPOSIDE; LEUKEMIA, PRE-B-CELL; LEUKEMIA, T-CELL; MEMBRANE LIPIDS; MICROSCOPY, ELECTRON; NEOPLASM PROTEINS; OLIGOPEPTIDES; POLY(ADP-RIBOSE) POLYMERASES; PROTO-ONCOGENE PROTEINS C-BCL-2; RECOMBINANT FUSION PROTEINS; TUMOR CELLS, CULTURED;

ANIMALIA; TRITIUM;

EID: 0033526089     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.145.1.99     Document Type: Article

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