Selective gene regulation with designed transcription factors: Implications for therapy

Current Opinion in Molecular Therapeutics

Volumn 5, Issue 2, 2003, Pages 161-166

  Falke, Dietmar ^a   Juliano, Rudy L ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Combinatorial library; Gene regulation; Phage display; Therapy; Transcription; Zinc finger

Indexed keywords

ADENOVIRUS VECTOR; ANTINEOPLASTIC AGENT; ANTISENSE OLIGONUCLEOTIDE; CYSTEINE; DNA; HISTIDINE; MULTIDRUG RESISTANCE PROTEIN 1; ONCOPROTEIN; PROTEIN BAX; PROTEIN P53; REPRESSOR PROTEIN; RETROVIRUS VECTOR; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR; VASCULOTROPIN; VIRUS PROTEIN; ZINC FINGER PROTEIN;

ANGIOGENESIS; COMBINATORIAL LIBRARY; DNA BINDING; DOWN REGULATION; DRUG DESIGN; DRUG RESISTANCE; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE STRUCTURE; GENE THERAPY; GENETIC REGULATION; GENETIC SELECTION; GENETIC TRANSCRIPTION; HERPES SIMPLEX VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS; IMMEDIATE EARLY GENE; INHIBITION KINETICS; LABORATORY TEST; LONG TERMINAL REPEAT; MAMMAL CELL; MOLECULAR RECOGNITION; NONHUMAN; PHAGE DISPLAY; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN ENGINEERING; PROTEIN TARGETING; REVIEW; TRANSCRIPTION REGULATION; UPREGULATION; VIRAL GENE DELIVERY SYSTEM; VIRUS REPLICATION; WOUND HEALING;

ADENOVIRIDAE; ANIMALS; DNA; DRUG DESIGN; GENE EXPRESSION REGULATION; GENETIC VECTORS; HUMANS; PROTEIN ENGINEERING; RETROVIRIDAE; TRANSCRIPTION FACTORS; TRANSFECTION; ZINC FINGERS;

ADENOVIRIDAE; ANIMALIA; HUMAN HERPESVIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS; MAMMALIA; SIMPLEXVIRUS; UNIDENTIFIED RETROVIRUS;

EID: 0037799676     PISSN: 14648431     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

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