-
1
-
-
0033521870
-
Molecular cloning, chromosome mapping and characterization of the mouse CRTH2 gene, a putative member of the leukocyte chemoattractant receptor family
-
Abe H, Takeshita T, Nagata K, Arita T, Endo Y, Fujita T, Takayama H, Kubo M, and Sugamura K (1999) Molecular cloning, chromosome mapping and characterization of the mouse CRTH2 gene, a putative member of the leukocyte chemoattractant receptor family. Gene 227:71-77.
-
(1999)
Gene
, vol.227
, pp. 71-77
-
-
Abe, H.1
Takeshita, T.2
Nagata, K.3
Arita, T.4
Endo, Y.5
Fujita, T.6
Takayama, H.7
Kubo, M.8
Sugamura, K.9
-
2
-
-
0023821185
-
The release of prostaglandin D2 from human skin in vivo and in vitro during immediate allergic reactions
-
Barr RM, Koro O, Francis DM, Black AK, Numata T, and Greaves MW (1988) The release of prostaglandin D2 from human skin in vivo and in vitro during immediate allergic reactions. Br J Pharmacol 94:773-780.
-
(1988)
Br J Pharmacol
, vol.94
, pp. 773-780
-
-
Barr, R.M.1
Koro, O.2
Francis, D.M.3
Black, A.K.4
Numata, T.5
Greaves, M.W.6
-
3
-
-
0029134144
-
Molecular cloning and characterization of the human prostanoid DP receptor
-
Boie Y, Sawyer N, Slipetz DM, Metters KM, and Abramovitz M (1995) Molecular cloning and characterization of the human prostanoid DP receptor. J Biol Chem 270:18910-18916.
-
(1995)
J Biol Chem
, vol.270
, pp. 18910-18916
-
-
Boie, Y.1
Sawyer, N.2
Slipetz, D.M.3
Metters, K.M.4
Abramovitz, M.5
-
4
-
-
0015861774
-
Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (150) of an enzymatic reaction
-
Cheng Y and Prusoff WH (1973) Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (150) of an enzymatic reaction. Biochem Pharmacol 22:3099-3108.
-
(1973)
Biochem Pharmacol
, vol.22
, pp. 3099-3108
-
-
Cheng, Y.1
Prusoff, W.H.2
-
5
-
-
0033784440
-
CRTH2 is the most reliable marker for the detection of circulating human type 2 Th and type 2 T cytotoxic cells in health and disease
-
Cosmi L, Annunziato F, Galli MIG, Maggi RME, Nagata K, and Romagnani S (2000) CRTH2 is the most reliable marker for the detection of circulating human type 2 Th and type 2 T cytotoxic cells in health and disease. Eur J Immunol 30:2972-2979.
-
(2000)
Eur J Immunol
, vol.30
, pp. 2972-2979
-
-
Cosmi, L.1
Annunziato, F.2
Galli, M.I.G.3
Maggi, R.M.E.4
Nagata, K.5
Romagnani, S.6
-
6
-
-
18344370479
-
2 attenuates the development of acute and chronic inflammation
-
2 attenuates the development of acute and chronic inflammation. Mol Pharmacol 61:997-1007.
-
(2002)
Mol Pharmacol
, vol.61
, pp. 997-1007
-
-
Cuzzocrea, S.1
Wayman, N.S.2
Mazzon, E.3
Dugo, L.4
Di Paola, R.5
Serraino, I.6
Britti, D.7
Chatterjee, P.K.8
Caputi, A.P.9
Thiemermann, C.10
-
7
-
-
0024472734
-
Prostaglandin D2 causes accumulation of eosinophils in the lumen of the dog trachea
-
Emery DL, Djokic TD, Graf PD, and Nadel JA (1989) Prostaglandin D2 causes accumulation of eosinophils in the lumen of the dog trachea. J Appl Physiol 67:959-962.
-
(1989)
J Appl Physiol
, vol.67
, pp. 959-962
-
-
Emery, D.L.1
Djokic, T.D.2
Graf, P.D.3
Nadel, J.A.4
-
8
-
-
0030028768
-
Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity and lung damage in a mouse asthma model
-
Foster PS, Hogan SP, Ramsay AJ, Matthaei KI, and Young IG (1996) Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity and lung damage in a mouse asthma model. J Exp Med 183:195-201.
-
(1996)
J Exp Med
, vol.183
, pp. 195-201
-
-
Foster, P.S.1
Hogan, S.P.2
Ramsay, A.J.3
Matthaei, K.I.4
Young, I.G.5
-
9
-
-
0036135587
-
Pronounced eosinophilic lung inflammation and Th2 cytokine release in human lipocalin-type prostaglandin D synthase transgenic mice
-
Fujitani Y, Kanaoka Y, Aritake K, Uodome N, Okazaki-Hatake K, and Urade Y (2002) Pronounced eosinophilic lung inflammation and Th2 cytokine release in human lipocalin-type prostaglandin D synthase transgenic mice. J Immunol 168: 443-449.
-
(2002)
J Immunol
, vol.168
, pp. 443-449
-
-
Fujitani, Y.1
Kanaoka, Y.2
Aritake, K.3
Uodome, N.4
Okazaki-Hatake, K.5
Urade, Y.6
-
10
-
-
0033557172
-
Impaired antibacterial host defense in mice lacking the N-formylpeptide receptor
-
Gao JL, Lee EJ, and Murphy PM (1999) Impaired antibacterial host defense in mice lacking the N-formylpeptide receptor. J Exp Med 189:657-662.
-
(1999)
J Exp Med
, vol.189
, pp. 657-662
-
-
Gao, J.L.1
Lee, E.J.2
Murphy, P.M.3
-
11
-
-
0035216234
-
Selective modulation of chemokinesis, degranulation and apoptosis in eosinophils through the PGD2 receptors CRTH2 and DP
-
Gervais FG, Cruz RP, Chateauneuf A, Gale S, Sawyer N, Nantel F, Metters KM, and O'Neill GP (2001) Selective modulation of chemokinesis, degranulation and apoptosis in eosinophils through the PGD2 receptors CRTH2 and DP. J Allergy Clin Immunol 108:982-988.
-
(2001)
J Allergy Clin Immunol
, vol.108
, pp. 982-988
-
-
Gervais, F.G.1
Cruz, R.P.2
Chateauneuf, A.3
Gale, S.4
Sawyer, N.5
Nantel, F.6
Metters, K.M.7
O'Neill, G.P.8
-
12
-
-
0023818286
-
The biology and pharmacology of PGD2
-
Giles H and Leff P (1988) The biology and pharmacology of PGD2. Prostaglandins 35:277-300.
-
(1988)
Prostaglandins
, vol.35
, pp. 277-300
-
-
Giles, H.1
Leff, P.2
-
13
-
-
0021141316
-
The bronchoconstrictor effect of inhaled prostaglandin D2 in normal and asthmatic men
-
Hardy CC, Robinson C, Tattersfield AE, and Holgate ST (1984) The bronchoconstrictor effect of inhaled prostaglandin D2 in normal and asthmatic men. N Engl J Med 311:209-213.
-
(1984)
N Engl J Med
, vol.311
, pp. 209-213
-
-
Hardy, C.C.1
Robinson, C.2
Tattersfield, A.E.3
Holgate, S.T.4
-
14
-
-
0036467528
-
12,14-PGJ2 induces IL-8 production in human T cells by a mitogen-activated protein kinase pathway
-
12,14-PGJ2 induces IL-8 production in human T cells by a mitogen-activated protein kinase pathway. J Immunol 168:1372-1379.
-
(2002)
J Immunol
, vol.168
, pp. 1372-1379
-
-
Harris, S.G.1
Smith, R.S.2
Phipps, R.P.3
-
15
-
-
0036467346
-
2 receptor, CRTH2
-
2 receptor, CRTH2. J Immunol 168:981-985.
-
(2002)
J Immunol
, vol.168
, pp. 981-985
-
-
Hirai, H.1
Tanaka, K.2
Takano, S.3
Ichimasa, M.4
Nakamura, M.5
Nagata, K.6
-
16
-
-
0035862329
-
Prostaglandin D2 selectively induces chemotaxis in T helper type 2 cells, eosinophils and basophils via seven-transmembrane receptor CRTH2
-
Hirai H, Tanaka K, Yoshie O, Ogawa K, Kenmotsu K, Takamori Y, Ichimasa M, Sugamura K, Nakamura M, Takano S, and Nagata K (2001) Prostaglandin D2 selectively induces chemotaxis in T helper type 2 cells, eosinophils and basophils via seven-transmembrane receptor CRTH2. J Exp Med 193:255-261.
-
(2001)
J Exp Med
, vol.193
, pp. 255-261
-
-
Hirai, H.1
Tanaka, K.2
Yoshie, O.3
Ogawa, K.4
Kenmotsu, K.5
Takamori, Y.6
Ichimasa, M.7
Sugamura, K.8
Nakamura, M.9
Takano, S.10
Nagata, K.11
-
17
-
-
0027974137
-
Molecular characterization of a mouse prostaglandin D receptor and functional expression of the cloned gene
-
Hirata M, Kakizuka A, Aizawa M, Ushikubi F, and Narumiya S (1994) Molecular characterization of a mouse prostaglandin D receptor and functional expression of the cloned gene. Proc Natl Acad Sci USA 91:11192-11196.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 11192-11196
-
-
Hirata, M.1
Kakizuka, A.2
Aizawa, M.3
Ushikubi, F.4
Narumiya, S.5
-
18
-
-
0034635452
-
Central role for G protein-coupled phosphoinositide 3-kinase γ in inflammation
-
Hirsch E, Katanaev VL, Garlanda C, Azzolino O, Pirola L, Silengo L, Sozzani S, Mantovani A, Altruda F, and Wymann MP (2000) Central role for G protein-coupled phosphoinositide 3-kinase γ in inflammation. Science (Wash DC) 287: 1049-1053.
-
(2000)
Science (Wash DC)
, vol.287
, pp. 1049-1053
-
-
Hirsch, E.1
Katanaev, V.L.2
Garlanda, C.3
Azzolino, O.4
Pirola, L.5
Silengo, L.6
Sozzani, S.7
Mantovani, A.8
Altruda, F.9
Wymann, M.P.10
-
19
-
-
0028972026
-
A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation
-
Kliewer SA, Lenhard JM, Willson TM, Patel I, Morris DC, and Lehmann JM (1995) A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation. Cell 83:813-819.
-
(1995)
Cell
, vol.83
, pp. 813-819
-
-
Kliewer, S.A.1
Lenhard, J.M.2
Willson, T.M.3
Patel, I.4
Morris, D.C.5
Lehmann, J.M.6
-
20
-
-
0031013395
-
Peroxisome proliferator-activated receptors alpha and gamma are activated by indomethacin and other nonsteroidal anti-inflammatory drugs
-
Lehmann JM, Lenhard JM, Oliver BB, Ringold GM, and Kliewer SA (1997) Peroxisome proliferator-activated receptors alpha and gamma are activated by indomethacin and other nonsteroidal anti-inflammatory drugs. J Biol Chem 272:3406-3410.
-
(1997)
J Biol Chem
, vol.272
, pp. 3406-3410
-
-
Lehmann, J.M.1
Lenhard, J.M.2
Oliver, B.B.3
Ringold, G.M.4
Kliewer, S.A.5
-
21
-
-
0037119433
-
2 and the thiazolidinedione ciglitazone through peroxisome proliferator activator receptor £-independent mechanisms involving reactive oxygenated species
-
2 and the thiazolidinedione ciglitazone through peroxisome proliferator activator receptor £-independent mechanisms involving reactive oxygenated species. J Biol Chem 277:29681-29685.
-
(2002)
J Biol Chem
, vol.277
, pp. 29681-29685
-
-
Lennon, A.M.1
Ramauge, M.2
Dessouroux, A.3
Pierre, M.4
-
22
-
-
0020001399
-
Prostaglandin D2 generation after activation of rat and human mast cells with anti-IgE
-
Lewis RA, Soter NA, Diamond PT, Austen KF, Oates JA, and Roberts LJ 2nd (1982) Prostaglandin D2 generation after activation of rat and human mast cells with anti-IgE. J Immunol 129:1627-1631.
-
(1982)
J Immunol
, vol.129
, pp. 1627-1631
-
-
Lewis, R.A.1
Soter, N.A.2
Diamond, P.T.3
Austen, K.F.4
Oates, J.A.5
Roberts L.J. II6
-
23
-
-
0037100257
-
Cutting edge: Th2 cell trafficking into the allergic lung is dependent on chemoattractant receptor signaling
-
Mathew A, Medoff BD, Carafone AD, and Luster AD (2002) Cutting edge: Th2 cell trafficking into the allergic lung is dependent on chemoattractant receptor signaling. J Immunol 169:651-655.
-
(2002)
J Immunol
, vol.169
, pp. 651-655
-
-
Mathew, A.1
Medoff, B.D.2
Carafone, A.D.3
Luster, A.D.4
-
24
-
-
0034677595
-
Prostaglandin D2 as a mediator of allergic asthma
-
Matsuoka T, Hirata M, Tanaka H, Takahashi Y, Murata T, Kabashima K, Sugimoto Y, Kobayashi T, Ushikubi F, Aze Y, et al. (2000) Prostaglandin D2 as a mediator of allergic asthma. Science (Wash DC) 287:2013-2017.
-
(2000)
Science (Wash DC)
, vol.287
, pp. 2013-2017
-
-
Matsuoka, T.1
Hirata, M.2
Tanaka, H.3
Takahashi, Y.4
Murata, T.5
Kabashima, K.6
Sugimoto, Y.7
Kobayashi, T.8
Ushikubi, F.9
Aze, Y.10
-
25
-
-
0033560747
-
Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium
-
Meili R, Ellsworth C, Lee S, Reddy TB, Ma H, and Firtel RA (1999) Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium. EMBO (Eur Mol Biol Organ) J 18:2092-2105.
-
(1999)
EMBO (Eur Mol Biol Organ) J
, vol.18
, pp. 2092-2105
-
-
Meili, R.1
Ellsworth, C.2
Lee, S.3
Reddy, T.B.4
Ma, H.5
Firtel, R.A.6
-
26
-
-
0027146692
-
Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase
-
Mitchell JA, Akarasereenont P, Thiemermann C, Flower RJ, and Vane JR (1993) Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase. Proc Natl Acad Sci USA 90:11693-11697.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 11693-11697
-
-
Mitchell, J.A.1
Akarasereenont, P.2
Thiemermann, C.3
Flower, R.J.4
Vane, J.R.5
-
29
-
-
0022557575
-
Release of prostaglandin D2 into human airways during acute antigen challenge
-
Murray JJ, Tonnel AB, Brash AR, Roberts LJ 2nd, Gosset P, Workman R, Capron A, and Oates JA (1986) Release of prostaglandin D2 into human airways during acute antigen challenge. N Engl J Med 315:800-804.
-
(1986)
N Engl J Med
, vol.315
, pp. 800-804
-
-
Murray, J.J.1
Tonnel, A.B.2
Brash, A.R.3
Roberts L.J. II4
Gosset, P.5
Workman, R.6
Capron, A.7
Oates, J.A.8
-
30
-
-
0032829392
-
CRTH2, an orphan receptor of T-helper-2-cells, is expressed on basophils and eosinophils and responds to mast cell-derived factor(s)
-
Nagata K, Hirai H, Tanaka K, Ogawa K, Aso T, Sugamura K, Nakamura M, and Takano S (1999) CRTH2, an orphan receptor of T-helper-2-cells, is expressed on basophils and eosinophils and responds to mast cell-derived factor(s). FEBS Lett 459:195-199.
-
(1999)
FEBS Lett
, vol.459
, pp. 195-199
-
-
Nagata, K.1
Hirai, H.2
Tanaka, K.3
Ogawa, K.4
Aso, T.5
Sugamura, K.6
Nakamura, M.7
Takano, S.8
-
32
-
-
0030823258
-
The phosphatidylinositol 3-kinase inhibitor wortmannin markedly reduces chemotactic peptide-induced locomotion and increases in cytoskeletal actin in human neutrophils
-
Niggli V and Keller H (1997) The phosphatidylinositol 3-kinase inhibitor wortmannin markedly reduces chemotactic peptide-induced locomotion and increases in cytoskeletal actin in human neutrophils. Eur J Pharmacol 335:43-52.
-
(1997)
Eur J Pharmacol
, vol.335
, pp. 43-52
-
-
Niggli, V.1
Keller, H.2
-
33
-
-
0032538463
-
2+ mobilization, Ras-mitogen-activated protein kinase activation and adenylate cyclase inhibition
-
2+ mobilization, Ras-mitogen-activated protein kinase activation and adenylate cyclase inhibition. J Biol Chem 273:27104-27110.
-
(1998)
J Biol Chem
, vol.273
, pp. 27104-27110
-
-
Okamoto, H.1
Takuwa, N.2
Gonda, K.3
Okazaki, H.4
Chang, K.5
Yatomi, Y.6
Shigematsu, H.7
Takuwa, Y.8
-
34
-
-
15444353437
-
Novel C5a receptor antagonists regulate neutrophil functions in vitro and in vivo
-
Pellas TC, Boyar W, van Oostrum J, Wasvary J, Fryer LR, Pastor G, Sills M, Braunwalder A, Yarwood DR, Kramer R, et al. (1998) Novel C5a receptor antagonists regulate neutrophil functions in vitro and in vivo. J Immunol 160:5616-5621.
-
(1998)
J Immunol
, vol.160
, pp. 5616-5621
-
-
Pellas, T.C.1
Boyar, W.2
Van Oostrum, J.3
Wasvary, J.4
Fryer, L.R.5
Pastor, G.6
Sills, M.7
Braunwalder, A.8
Yarwood, D.R.9
Kramer, R.10
-
35
-
-
0036944934
-
2 receptor, CRTH2
-
2 receptor, CRTH2. Br J Pharmacol 137:1163-1172.
-
(2002)
Br J Pharmacol
, vol.137
, pp. 1163-1172
-
-
Sawyer, N.1
Cauchon, E.2
Chateauneuf, A.3
Cruz, R.P.4
Nicholson, D.W.5
Metters, K.M.6
O'Neill, G.P.7
Gervais, F.G.8
-
36
-
-
0037155868
-
12,14-prostaglandin J2. A prostaglandin D2 metabolite generated during inflammatory processes
-
12,14-prostaglandin J2. A prostaglandin D2 metabolite generated during inflammatory processes. J Biol Chem 277:10459-10466.
-
(2002)
J Biol Chem
, vol.277
, pp. 10459-10466
-
-
Shibata, T.1
Kondo, M.2
Osawa, T.3
Shibata, N.4
Kobayashi, M.5
Uchida, K.6
-
38
-
-
17344394207
-
i-coupled receptor Edg-1 and intracellular to regulate proliferation and survival
-
i-coupled receptor Edg-1 and intracellular to regulate proliferation and survival. J Cell Biol 142:229-240.
-
(1998)
J Cell Biol
, vol.142
, pp. 229-240
-
-
Van Brocklyn, J.R.1
Lee, M.J.2
Menzeleev, R.3
Olivera, A.4
Edsall, L.5
Cuvillier, O.6
Thomas, D.M.7
Coopman, P.J.8
Thangada, S.9
Liu, C.H.10
Hla, T.11
Spiegel, S.12
-
39
-
-
0037096205
-
Prostaglandin D2 and its metabolites induce caspase-dependent granulocyte apoptosis that is mediated via inhibition of I‰B$ degradation using a peroxisome proliferator-activated receptor-£-independent mechanism
-
Ward C, Dransfield I, Murray J, Farrow SN, Haslett C, and Rossi AG (2002) Prostaglandin D2 and its metabolites induce caspase-dependent granulocyte apoptosis that is mediated via inhibition of I‰B$ degradation using a peroxisome proliferator-activated receptor-£-independent mechanism. J Immunol 168:6232-6243.
-
(2002)
J Immunol
, vol.168
, pp. 6232-6243
-
-
Ward, C.1
Dransfield, I.2
Murray, J.3
Farrow, S.N.4
Haslett, C.5
Rossi, A.G.6
-
40
-
-
0032545213
-
Interleukin-13: Central mediator of allergic asthma
-
Wills-Karp M, Luyimbazi J, Xu X, Schofield B, Neben TY, Karp CL, and Donaldson DD (1998) Interleukin-13: central mediator of allergic asthma. Science (Wash DC) 282:2258-2261.
-
(1998)
Science (Wash DC)
, vol.282
, pp. 2258-2261
-
-
Wills-Karp, M.1
Luyimbazi, J.2
Xu, X.3
Schofield, B.4
Neben, T.Y.5
Karp, C.L.6
Donaldson, D.D.7
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