메뉴 건너뛰기




Volumn 306, Issue 2, 2003, Pages 463-470

Expression and molecular pharmacology of the mouse CRTH2 receptor

Author keywords

[No Author keywords available]

Indexed keywords

13,14 DIHYDRO 15 OXOPROSTAGLANDIN D2; 15 DEOXY DELTA12,14 PROSTAGLANDIN J2; 5 (6 CARBOXYHEXYL) 1 (3 CYCLOHEXYL 3 HYDROXYPROPYL)HYDANTOIN; ACETYLSALICYLIC ACID; CRTH2 RECEPTOR; CYCLIC AMP; DP RECEPTOR; FLURBIPROFEN; G PROTEIN COUPLED RECEPTOR; IBUPROFEN; INDOMETACIN; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; NONSTEROID ANTIINFLAMMATORY AGENT; PARACETAMOL; PERTUSSIS TOXIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROSTAGLANDIN D2; PROSTAGLANDIN E2; PROSTAGLANDIN F2 ALPHA; PROSTAGLANDIN J2; PROSTANOID; SALICYLATE SODIUM; SALICYLIC ACID; SULINDAC; UNCLASSIFIED DRUG; WORTMANNIN;

EID: 0037622765     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.103.050955     Document Type: Article
Times cited : (65)

References (40)
  • 1
    • 0033521870 scopus 로고    scopus 로고
    • Molecular cloning, chromosome mapping and characterization of the mouse CRTH2 gene, a putative member of the leukocyte chemoattractant receptor family
    • Abe H, Takeshita T, Nagata K, Arita T, Endo Y, Fujita T, Takayama H, Kubo M, and Sugamura K (1999) Molecular cloning, chromosome mapping and characterization of the mouse CRTH2 gene, a putative member of the leukocyte chemoattractant receptor family. Gene 227:71-77.
    • (1999) Gene , vol.227 , pp. 71-77
    • Abe, H.1    Takeshita, T.2    Nagata, K.3    Arita, T.4    Endo, Y.5    Fujita, T.6    Takayama, H.7    Kubo, M.8    Sugamura, K.9
  • 2
    • 0023821185 scopus 로고
    • The release of prostaglandin D2 from human skin in vivo and in vitro during immediate allergic reactions
    • Barr RM, Koro O, Francis DM, Black AK, Numata T, and Greaves MW (1988) The release of prostaglandin D2 from human skin in vivo and in vitro during immediate allergic reactions. Br J Pharmacol 94:773-780.
    • (1988) Br J Pharmacol , vol.94 , pp. 773-780
    • Barr, R.M.1    Koro, O.2    Francis, D.M.3    Black, A.K.4    Numata, T.5    Greaves, M.W.6
  • 3
    • 0029134144 scopus 로고
    • Molecular cloning and characterization of the human prostanoid DP receptor
    • Boie Y, Sawyer N, Slipetz DM, Metters KM, and Abramovitz M (1995) Molecular cloning and characterization of the human prostanoid DP receptor. J Biol Chem 270:18910-18916.
    • (1995) J Biol Chem , vol.270 , pp. 18910-18916
    • Boie, Y.1    Sawyer, N.2    Slipetz, D.M.3    Metters, K.M.4    Abramovitz, M.5
  • 4
    • 0015861774 scopus 로고
    • Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (150) of an enzymatic reaction
    • Cheng Y and Prusoff WH (1973) Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (150) of an enzymatic reaction. Biochem Pharmacol 22:3099-3108.
    • (1973) Biochem Pharmacol , vol.22 , pp. 3099-3108
    • Cheng, Y.1    Prusoff, W.H.2
  • 5
    • 0033784440 scopus 로고    scopus 로고
    • CRTH2 is the most reliable marker for the detection of circulating human type 2 Th and type 2 T cytotoxic cells in health and disease
    • Cosmi L, Annunziato F, Galli MIG, Maggi RME, Nagata K, and Romagnani S (2000) CRTH2 is the most reliable marker for the detection of circulating human type 2 Th and type 2 T cytotoxic cells in health and disease. Eur J Immunol 30:2972-2979.
    • (2000) Eur J Immunol , vol.30 , pp. 2972-2979
    • Cosmi, L.1    Annunziato, F.2    Galli, M.I.G.3    Maggi, R.M.E.4    Nagata, K.5    Romagnani, S.6
  • 7
    • 0024472734 scopus 로고
    • Prostaglandin D2 causes accumulation of eosinophils in the lumen of the dog trachea
    • Emery DL, Djokic TD, Graf PD, and Nadel JA (1989) Prostaglandin D2 causes accumulation of eosinophils in the lumen of the dog trachea. J Appl Physiol 67:959-962.
    • (1989) J Appl Physiol , vol.67 , pp. 959-962
    • Emery, D.L.1    Djokic, T.D.2    Graf, P.D.3    Nadel, J.A.4
  • 8
    • 0030028768 scopus 로고    scopus 로고
    • Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity and lung damage in a mouse asthma model
    • Foster PS, Hogan SP, Ramsay AJ, Matthaei KI, and Young IG (1996) Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity and lung damage in a mouse asthma model. J Exp Med 183:195-201.
    • (1996) J Exp Med , vol.183 , pp. 195-201
    • Foster, P.S.1    Hogan, S.P.2    Ramsay, A.J.3    Matthaei, K.I.4    Young, I.G.5
  • 9
    • 0036135587 scopus 로고    scopus 로고
    • Pronounced eosinophilic lung inflammation and Th2 cytokine release in human lipocalin-type prostaglandin D synthase transgenic mice
    • Fujitani Y, Kanaoka Y, Aritake K, Uodome N, Okazaki-Hatake K, and Urade Y (2002) Pronounced eosinophilic lung inflammation and Th2 cytokine release in human lipocalin-type prostaglandin D synthase transgenic mice. J Immunol 168: 443-449.
    • (2002) J Immunol , vol.168 , pp. 443-449
    • Fujitani, Y.1    Kanaoka, Y.2    Aritake, K.3    Uodome, N.4    Okazaki-Hatake, K.5    Urade, Y.6
  • 10
    • 0033557172 scopus 로고    scopus 로고
    • Impaired antibacterial host defense in mice lacking the N-formylpeptide receptor
    • Gao JL, Lee EJ, and Murphy PM (1999) Impaired antibacterial host defense in mice lacking the N-formylpeptide receptor. J Exp Med 189:657-662.
    • (1999) J Exp Med , vol.189 , pp. 657-662
    • Gao, J.L.1    Lee, E.J.2    Murphy, P.M.3
  • 12
    • 0023818286 scopus 로고
    • The biology and pharmacology of PGD2
    • Giles H and Leff P (1988) The biology and pharmacology of PGD2. Prostaglandins 35:277-300.
    • (1988) Prostaglandins , vol.35 , pp. 277-300
    • Giles, H.1    Leff, P.2
  • 13
    • 0021141316 scopus 로고
    • The bronchoconstrictor effect of inhaled prostaglandin D2 in normal and asthmatic men
    • Hardy CC, Robinson C, Tattersfield AE, and Holgate ST (1984) The bronchoconstrictor effect of inhaled prostaglandin D2 in normal and asthmatic men. N Engl J Med 311:209-213.
    • (1984) N Engl J Med , vol.311 , pp. 209-213
    • Hardy, C.C.1    Robinson, C.2    Tattersfield, A.E.3    Holgate, S.T.4
  • 14
    • 0036467528 scopus 로고    scopus 로고
    • 12,14-PGJ2 induces IL-8 production in human T cells by a mitogen-activated protein kinase pathway
    • 12,14-PGJ2 induces IL-8 production in human T cells by a mitogen-activated protein kinase pathway. J Immunol 168:1372-1379.
    • (2002) J Immunol , vol.168 , pp. 1372-1379
    • Harris, S.G.1    Smith, R.S.2    Phipps, R.P.3
  • 17
    • 0027974137 scopus 로고
    • Molecular characterization of a mouse prostaglandin D receptor and functional expression of the cloned gene
    • Hirata M, Kakizuka A, Aizawa M, Ushikubi F, and Narumiya S (1994) Molecular characterization of a mouse prostaglandin D receptor and functional expression of the cloned gene. Proc Natl Acad Sci USA 91:11192-11196.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 11192-11196
    • Hirata, M.1    Kakizuka, A.2    Aizawa, M.3    Ushikubi, F.4    Narumiya, S.5
  • 19
    • 0028972026 scopus 로고
    • A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation
    • Kliewer SA, Lenhard JM, Willson TM, Patel I, Morris DC, and Lehmann JM (1995) A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation. Cell 83:813-819.
    • (1995) Cell , vol.83 , pp. 813-819
    • Kliewer, S.A.1    Lenhard, J.M.2    Willson, T.M.3    Patel, I.4    Morris, D.C.5    Lehmann, J.M.6
  • 20
    • 0031013395 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors alpha and gamma are activated by indomethacin and other nonsteroidal anti-inflammatory drugs
    • Lehmann JM, Lenhard JM, Oliver BB, Ringold GM, and Kliewer SA (1997) Peroxisome proliferator-activated receptors alpha and gamma are activated by indomethacin and other nonsteroidal anti-inflammatory drugs. J Biol Chem 272:3406-3410.
    • (1997) J Biol Chem , vol.272 , pp. 3406-3410
    • Lehmann, J.M.1    Lenhard, J.M.2    Oliver, B.B.3    Ringold, G.M.4    Kliewer, S.A.5
  • 21
    • 0037119433 scopus 로고    scopus 로고
    • 2 and the thiazolidinedione ciglitazone through peroxisome proliferator activator receptor £-independent mechanisms involving reactive oxygenated species
    • 2 and the thiazolidinedione ciglitazone through peroxisome proliferator activator receptor £-independent mechanisms involving reactive oxygenated species. J Biol Chem 277:29681-29685.
    • (2002) J Biol Chem , vol.277 , pp. 29681-29685
    • Lennon, A.M.1    Ramauge, M.2    Dessouroux, A.3    Pierre, M.4
  • 22
  • 23
    • 0037100257 scopus 로고    scopus 로고
    • Cutting edge: Th2 cell trafficking into the allergic lung is dependent on chemoattractant receptor signaling
    • Mathew A, Medoff BD, Carafone AD, and Luster AD (2002) Cutting edge: Th2 cell trafficking into the allergic lung is dependent on chemoattractant receptor signaling. J Immunol 169:651-655.
    • (2002) J Immunol , vol.169 , pp. 651-655
    • Mathew, A.1    Medoff, B.D.2    Carafone, A.D.3    Luster, A.D.4
  • 25
    • 0033560747 scopus 로고    scopus 로고
    • Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium
    • Meili R, Ellsworth C, Lee S, Reddy TB, Ma H, and Firtel RA (1999) Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium. EMBO (Eur Mol Biol Organ) J 18:2092-2105.
    • (1999) EMBO (Eur Mol Biol Organ) J , vol.18 , pp. 2092-2105
    • Meili, R.1    Ellsworth, C.2    Lee, S.3    Reddy, T.B.4    Ma, H.5    Firtel, R.A.6
  • 26
    • 0027146692 scopus 로고
    • Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase
    • Mitchell JA, Akarasereenont P, Thiemermann C, Flower RJ, and Vane JR (1993) Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase. Proc Natl Acad Sci USA 90:11693-11697.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 11693-11697
    • Mitchell, J.A.1    Akarasereenont, P.2    Thiemermann, C.3    Flower, R.J.4    Vane, J.R.5
  • 30
    • 0032829392 scopus 로고    scopus 로고
    • CRTH2, an orphan receptor of T-helper-2-cells, is expressed on basophils and eosinophils and responds to mast cell-derived factor(s)
    • Nagata K, Hirai H, Tanaka K, Ogawa K, Aso T, Sugamura K, Nakamura M, and Takano S (1999) CRTH2, an orphan receptor of T-helper-2-cells, is expressed on basophils and eosinophils and responds to mast cell-derived factor(s). FEBS Lett 459:195-199.
    • (1999) FEBS Lett , vol.459 , pp. 195-199
    • Nagata, K.1    Hirai, H.2    Tanaka, K.3    Ogawa, K.4    Aso, T.5    Sugamura, K.6    Nakamura, M.7    Takano, S.8
  • 32
    • 0030823258 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-kinase inhibitor wortmannin markedly reduces chemotactic peptide-induced locomotion and increases in cytoskeletal actin in human neutrophils
    • Niggli V and Keller H (1997) The phosphatidylinositol 3-kinase inhibitor wortmannin markedly reduces chemotactic peptide-induced locomotion and increases in cytoskeletal actin in human neutrophils. Eur J Pharmacol 335:43-52.
    • (1997) Eur J Pharmacol , vol.335 , pp. 43-52
    • Niggli, V.1    Keller, H.2
  • 39
    • 0037096205 scopus 로고    scopus 로고
    • Prostaglandin D2 and its metabolites induce caspase-dependent granulocyte apoptosis that is mediated via inhibition of I‰B$ degradation using a peroxisome proliferator-activated receptor-£-independent mechanism
    • Ward C, Dransfield I, Murray J, Farrow SN, Haslett C, and Rossi AG (2002) Prostaglandin D2 and its metabolites induce caspase-dependent granulocyte apoptosis that is mediated via inhibition of I‰B$ degradation using a peroxisome proliferator-activated receptor-£-independent mechanism. J Immunol 168:6232-6243.
    • (2002) J Immunol , vol.168 , pp. 6232-6243
    • Ward, C.1    Dransfield, I.2    Murray, J.3    Farrow, S.N.4    Haslett, C.5    Rossi, A.G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.