Caspase activity is required for stimulated B Lymphocytes to enter the cell cycle

Journal of Immunology

Volumn 170, Issue 12, 2003, Pages 6065-6072

  Olson, N Eric ^a   Graves, Jonathan D ^a   Shu, Geraldine L ^a   Ryan, Elizabeth J ^a   Clark, Edward A ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS INHIBITOR; APOPTOSIS INHIBITOR 2; AT RICH SEQUENCE BINDING PROTEIN 1; BINDING PROTEIN; CASPASE; CASPASE 3; CASPASE 6; CASPASE 8; CASPASE INHIBITOR; CD40 ANTIGEN; CD40 LIGAND; CYCLIN D; CYCLIN DEPENDENT KINASE; INTERLEUKIN 6; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 3; SURVIVAL FACTOR; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; AT RICH SEQUENCE; B LYMPHOCYTE ACTIVATION; CELL ASSAY; CELL CYCLE; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL DIVISION; CELL SURVIVAL; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME SPECIFICITY; ENZYME SUBSTRATE; GENE EXPRESSION REGULATION; GENE INDUCTION; HUMAN; HUMAN CELL; LYMPHOCYTE PROLIFERATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; TONSIL; TRANSCRIPTION REGULATION;

EID: 0037605790     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.170.12.6065     Document Type: Article

References (41)

1. Agenes, F., M. M. Rosado, and A. A. Freitas. 1997. Independent homeostatic regulation of B cell compartments. Eur. J. Immunol. 27:1801.
2. Lam, K. P., R. Kuhn, and K. Rajewsky. 1997. In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death. Cell 90:1073.
3. Loder, F., B. Mutschler, R. J. Ray, C. J. Paige, P. Sideras, R. Torres, M. C. Lamers, and R. Carsetti. 1999. B cell development in the spleen takes place in discrete steps and is determined by the quality of B cell receptor-derived signals. J. Exp. Med. 190:75.
4. Tanchot, C., M. M. Rosado, F. Agenes, A. A. Freitas, and B. Rocha. 1997. Lymphocyte homeostasis. Semin. Immunol. 9:331.
5. Glynne, R., S. Akkaraju, J. I. Healy, J. Rayner, C. C. Goodnow, and D. H. Mack. 2000b. How self-tolerance and the immunosuppressive drug FK506 prevent B-cell mitogenesis. Nature 403:672.
6. Glynne, R., G. Ghandour, J. Rayner, D. H. Mack, and C. C. Goodnow. 2000a. B-lymphocyte quiescence, tolerance and activation as viewed by global gene expression profiling on microarrays. Immunol. Rev. 176:216.
7. Kuo, C. T., M. L. Veselits, and J. M. Leiden. 1997. LKLF: a transcriptional regulator of single-positive T cell quiescence and survival. Science 277:1986.
8. Kohwi-Shigematsu, T., K. Maass, and J. Bode. 1997. A thymocyte factor SATB1 suppresses transcription of stably integrated matrix-attachment region-linked reporter genes. Biochemistry 36:12005.
9. Earnshaw, W. C., L. M. Martins, and S. H. Kaufmann. 1999. Mammalian caspases: structure, activation, substrates, and functions during apoptosis. Annu. Rev. Biochem. 68:383.
10. Budd, R. C. 2001. Activation-induced cell death. Curr. Opin. Immunol. 13:356.
11. Janicke, R. U., P. A. Walker, X. Y. Lin, and A. G. Porter. 1996. Specific cleavage of the retinoblastoma protein by an ICE-like protease in apoptosis. EMBO J. 15:6969.
12. Levkau, B., H. Koyama, E. W. Raines, B. E. Clurman, B. Herren, K. Orth, J. M. Roberts, and R. Ross. 1998. Cleavage of p21Cip1/Waf1 and p27Kip1 mediates apoptosis in endothelial cells through activation of Cdk2: role of a caspase cascade. Mol. Cell 1:553.
13. Los, M., C. Stroh, R. U. Janicke, I. H. Engels, and K. Schulze-Osthoff. 2001. Caspases: more than just killers? Trends Immunol. 22:31.
14. Zhang, J., D. Cado, A. Chen, N. H. Kabra, and A. Winoto. 1998. Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1. Nature 392:296.
15. Walsh, C. M., B. G. Wen, A. M. Chinnaiyan, K. O'Rourke, V. M. Dixit, and S. M. Hedrick. 1998. A role for FADD in T cell activation and development. Immunity 8:439.
16. Newton, K., A. W. Harris, M. L. Bath, K. G. Smith, and A. Strasser. 1998. A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes. EMBO J. 17:706.
17. Alam, A., L. Y. Cohen, S. Aouad, and R. P. Sekaly. 1999. Early activation of caspases during T lymphocyte stimulation results in selective substrate cleavage in nonapoptotic cells. J. Exp. Med. 190:1879.
18. Kennedy, N. J., T. Kataoka, J. Tschopp, and R. C. Budd. 1999. Caspase activation is required for T cell proliferation. J. Exp. Med. 190:1891.
19. Chun H. J., L. Zheng, M. Ahmad, J. Wang, C. K. Speirs, R. M. Siegel, J. K. Dale, J. Puck, J. Davis, C. G. Hall, et al. 2002. Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency. Nature 419:395.
20. Valentine, M. A., E. A. Clark, G. L. Shu, N. A. Norris, and J. A. Ledbetter. 1988. Antibody to a novel 95-kDa surface glycoprotein on human B cells induces calcium mobilization and B cell activation. J. Immunol. 140:4071.
21. Clark, E. A., G. L. Shu, B. Luscher, K. E. Draves, J. Banchereau, J. A. Ledbetter, and M. A. Valentine. 1989. Activation of human B cells: comparison of the signal transduced by interleukin-4 to four different competence signals. J. Immunol. 143:3873.
22. Otipoby, K. L., K. B. Andersson, K. E. Draves, A. G. Farr, S. J. Klaus. J. D. Kerner, R. M. Perlmutter, C. L. Law, and E. A. Clark. 1996. CD22 regulates thymus-independent responses and the fate of long-lived B cells. Nature 384:634.
23. Clark, E. A., and J. A. Ledbetter. 1986. Activation of human B cells mediated through two distinct cell surface differentiation antigens, Bp35 and Bp50. Proc. Nat. Acad. Sci. USA 83:4494.
24. Otipoby, K. L., Y. Nagai, G. L. Shu, K. Miyake, and E. A. Clark. 2001. CD180 (RP105/Bgp95) workshop report. In Leukocyte Typing, Vol. 7. D. Y. Mason, ed. Oxford University Press, Oxford, p. 120.
25. Aicher, A., G. L. Shu, D. Magaletti, T. Mulvania, A. Pezzutto, A. Craxton, and E. A. Clark. 1999. Differential role for p38 mitogen-activated protein kinase in regulating CD40-induced gene expression in dendritic cells and B cells. J. Immunol. 163:5786.
26. Galande, S., L. A. Dickinson, I. S. Mian, M. Sikorska, and T. Kohwi-Shigematsu. 2001. SATB1 cleavage by caspase-6 disrupts PDZ domain-mediated dimerization causing detachment from chromatin early in T-cell apoptosis. Mol. Cell. Biol. 21:5591.
27. Tewari, M., L. T. Quan, K. O'Rourke, S. Desnoyers, Z. Zeng, D. R. Beidler, G. G. Poirier, G. S. Salvesen, and V. M. Dixit. 1995. Yama/CPP32β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase. Cell 81:801.
28. Craxton, A., G. Shu, J. D. Graves, J. Saklatvala, E. G. Krebs, and E. A. Clark. 1998. p38 MAPK is required for CD40-induced gene expression and proliferation in B lymphocytes. J. Immunol. 161:3225.
29. Roy, N., Q. L. Deveraux, R. Takahashi, G. S. Salvesen, and J. C. Reed. 1997. The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases. EMBO J. 16:6914.
30. Clark, E. A., and G. Shu. 1990. Association between IL-6 and CD40 signaling; IL-6 induces phosphorylation of CD40 receptors. J. Immunol. 145:1400.
31. Rousset, F., E. Garcia, T. Defrance, C. Peronne, N. Vezzio, D. H. Hsu, R. Kastelein, K. W. Moore, and J. Banchereau. 1992. Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes. Proc. Natl. Acad. Sci. USA 89:1890.
32. Liu, Y. J., D. Y. Mason, G. D. Johnson, S. Abbot, C. D. Gregory, D. L. Hardie, J. Gordon, and I. C. MacLennan. 1991. Germinal center cells express bcl-2 protein after activation by signals which prevent their entry into apoptosis. Eur. J. Immunol. 21:1905.
33. Ishida, T., N. Kobayashi, T. Tojo, S. Ishida, T. Yamamoto, and J. Inoue. 1995. CD40 signaling-mediated induction of Bcl-XL, Cdk4, and Cdk6. Implication of their cooperation in selective B cell growth. J. Immunol. 155:5527.
34. Lee, H. H., H. Dadgostar, Q. Cheng, J. Shu, and G. Cheng. 1999. NF-kappaB-mediated upregulation of Bcl-x and Bfl-1/A1 is required for CD40 survival signaling in B lymphocytes. Proc. Natl. Acad. Sci. USA 96:9136.
35. Suzuki, Y., Y. Nakabayashi, and R. Takahashi. 2001. Ubiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell death. Proc. Natl. Acad. Sci. USA 98:8662.
36. Cowling, V., and J. Downward. 2002. Caspase-6 is the direct activator of caspase-8 in the cytochrome c-induced apoptosis pathway: absolute requirement for removal of caspase-6 prodomain. Cell Death Differ. 9:1046.
37. Richards, J. D., S. H. Dave, C. H. Chou, A. A. Mamchak, and A. L. DeFranco. 2001. Inhibition of the MEK/ERK signaling pathway blocks a subset of B cell responses to antigen. J. Immunol. 166:3846.
38. Ruchaud, S., N. Korfali, P. Villa, T. J. Kottke, C. Dingwall, S. H. Kaufmann, and W. C. Earnshaw. 2002. Caspase-6 gene disruption reveals a requirement for lamin A cleavage in apoptotic chromatin condensation. EMBO J. 21:1967.
39. Frost, V., S. Al-Mehairi, and A. J. Sinclair. 2001. Exploitation of a non-apoptotic caspase to regulate the abundance of the cdkI p27(KIP1) in transformed lymphoid cells. Oncogene 20:2737.
40. Dickinson, L. A., T. Joh, Y. Kohwi, and T. Kohwi-Shigematsu. 1992. A tissue-specific MAR/SAR DNA-binding protein with unusual binding site recognition. Cell 70:631.
41. Liu, J., D. Bramblett, Q. Zhu, M. Lozano, R. Kobayashi, S. R. Ross, and J. P. Dudley. 1997. The matrix attachment region-binding protein SATB1 participates in negative regulation of tissue-specific gene expression. Mol. Cell. Biol. 17:5275.