Unanticipated inhibition of the metallo-β-lactamase from Bacteroides fragilis by 4-morpholineethanesulfonic acid (MES): A crystallographic study at 1.85-Å Resolution

Biochemistry

Volumn 37, Issue 19, 1998, Pages 6791-6800

  Fitzgerald, Paula M D ^a,b   Wu, Joseph K ^a   Toney, Jeffrey H ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA LACTAMASE;

ARTICLE; BACILLUS SUBTILIS; COMPETITIVE INHIBITION; CRYSTALLOGRAPHY; ENZYME CONFORMATION; ENZYME INHIBITION; ENZYME ISOLATION; HYDROGEN BOND; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ANALYSIS;

ALKANESULFONIC ACIDS; BACTEROIDES FRAGILIS; BETA-LACTAMASES; BINDING SITES; BUFFERS; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; LIGANDS; MODELS, MOLECULAR; MORPHOLINES; PROTEIN BINDING; PROTEIN CONFORMATION;

BACILLUS SUBTILIS; BACTERIA (MICROORGANISMS); BACTEROIDES FRAGILIS;

EID: 0032510815     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9730339     Document Type: Article

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