Defined human cellular systems in the study of glioma development

Frontiers in Bioscience

Volumn 8, Issue SUPPL., 2003, Pages

  Pieper, Russell O ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Astrocyte; Cancer; Glioma; Review; Transformation; Tumor

Indexed keywords

PROTEIN DERIVATIVE;

ASTROCYTOSIS; BIOLISTIC TRANSFORMATION; CANCER GRADING; CARCINOGENESIS; CELL INTERACTION; CLINICAL FEATURE; CORRELATION ANALYSIS; DISEASE ASSOCIATION; DISEASE COURSE; GENE DISRUPTION; GENE EXPRESSION; GENETIC DISORDER; GENETIC STABILITY; GLIOMA; HUMAN; MEDICAL ASSESSMENT; MOLECULAR DYNAMICS; MOLECULAR MECHANICS; NONHUMAN; ONCOGENE; PHENOTYPE; REVIEW; SIGNAL TRANSDUCTION; TANDEM REPEAT; ANIMAL; ASTROCYTE; CHEMISTRY; GENETICS; METABOLISM; MUTATION; PATHOLOGY; TUMOR CELL LINE;

ANIMALIA;

ANIMALS; ASTROCYTES; CELL LINE, TUMOR; GLIOMA; HUMANS; MUTATION;

EID: 0037558362     PISSN: 27686701     EISSN: 27686698     Source Type: Journal    
DOI: 10.2741/983     Document Type: Review

References (55)

1. CBTRUS (2000). Statistical Report: Primary Brain Tumors in the United States, 1992-1997. Published by the Central Brain Tumor Registry of the United States.
2. Rich, J.N., C. Guo, R.E.McLendon, D.D. Bigner, X.-F. Wang & C.M. Counter: A genetically tractable model of human glioma formation. Cancer Res. 61, 3356-3360 (2001)
3. Sonoda, Y., T. Ozawa, Y. Hirose, K.D. Aldape, M. McMahon; M.S. Berger & R.O. Pieper. Formation of intracranial tumors by genetically modified human astrocytes defines four pathways critical in the development of human anaplastic astrocytomas: Cancer Res. 61, 4956-4960 (2001)
4. Sonoda, Y., T. Ozawa, K.D. Aldape, D.F. Deen, M.S. Berger & R.O. Pieper: Akt pathway activation converts anaplastic astrocytoma to glioblastoma multiforme in a human astrocyte model of glioma. Cancer Res. 61, 6674-6678 (2001)
5. Kleihues, P., and Cavenee, W.K. World Health Organization classification of tumors of the central nervous system. IARC/WHO, Lyon (2000)
6. Hermanson, M., K. Funa, M. Hartman, L. Claesson-Welsh, C. Heldin, B. Westermark & M. Nister: Platelet-derived growth factor and its receptors in human glioma tissue: expression of messenger RNA and protein suggests the presence of autocrine and paracrine loops. Cancer Res. 52, 3213-3219 (1992)
7. Hermanson, M., K. Funa, J. Koopman, D. Maintz, A. Waha, B. Westermark, C. Heldin, O.D. Weistler, D.N. Louis, A. von Deimling & M. Nister: Association of loss of heterozygosity on chromosome 17p with high platelet-derived growth factor alpha receptor expression in human malignant gliomas. Cancer Res. 56, 164-171 (1996)
8. Kirsch, M., J.C. Wilson & P. Black: Platelet-derived growth factor in human brain tumors. J. Neuro-Onc. 35, 289-301 (1997)
9. Besson, A., and Yong, V.W. Mitogenic signaling and the relationship to cell cycle regulation in astrocytomas. J Neurooncol. 51, 245-64 (2001)
10. Bos, J.L. Ras oncogenes in human cancer: a review. Cancer Res. 49, 4682-4689 (1989)
11. Ichimura, K., M.B. Bolin, H.M. Goike, E.E. Schmidt, A. Moshref & V.P. Collins: Deregulation of the p14ARF/MDM2/p53 pathway is a prerequisite for human astrocytic gliomas with G1-S transition control gene abnormalities. Cancer Res. 60, 417-424 (2000)
12. Hiraga, S., T. Ohnishi, S. Izumoto, E. Miyahara, Y. Kanemura, H. Matsumura & N. Arita: Telomerase activity and alterations in telomere length in human brain tumors. Cancer Res. 58, 2117-2125 (1999)
13. Feldkamp, M.M, P. Lala,, N. Lau, L. Roncari & A. Guha: Expression of activated epidermal growth factor receptors. Ras-guanosine tri phosphate, and mitogen-activated protein kinase in human glioblastoma multiforme specimens. Neurosurgery 45, 1442-53 (1999)
14. Chakravarti, J., J.S. Loeffler & N.J. Dyson: Insulin-like growth factor receptor I mediates resistance to anti-epidermal growth factor receptor therapy in primary human glioblastoma cells through continued activation of phosphoinositide 3-kinase signaling. Cancer Res. 62, 200-207 (2002).
15. Duerr, E.M., B. Rollbrocker, Y. Hayashi, N. Peters, B. Meyer-Pullitz & D.N. Louis: PTEN mutations in gliomas and glioneuronal tumors. Oncogene 16, 2259-2264 (1998)
16. Wang, S.I., J. Pue, J. Li, J.N. Bruce, P. Cairns, D. Sidransky & R. Parsons: Somatic mutations of PTEN in glioblastoma multiforme. Cancer Res. 57, 4183-4186, (1997)
17. Haas-Kogan, D., N. Shalev, M. Wong, G. Mills, G. Yount & D. Stokoe: Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC. Current Biology; 8, 1195-1198 (1998)
18. Frederick, L., X.-Y. Wang, G. Eley & C.D. James: Diversity and frequency of epidermal growth factor receptor mutations in human glioblastomas. Cancer Res., 60, 1383-1387 (2000)
19. Dai, C. & E.C. Holland: Glioma models. Biochim. Biophys. Acta 1551, M19-M27 (2001)
20. Reilly, K.M. & T. Jacks: Genetically engineered mouse models of astrocytoma: GEMs in the rough? Sem. in Cancer Biol. 11, 177-1980 (2001)
21. Hahn, W.C., C.M. Counter, A.S. Lundherg, R.L. Beijersbergen, M.W. Brooks & R.A. Weinberg: Creation of human tumor cells with defined genetic elements. Nature 400. 464-468 (1999)
22. Linardopoulos, S., A.J. Street, D.E. Quelle, D. Parry, G. Peters, C.J. Sherr & A. Balmain. Deletion and altered regulation of p16INK4a and p15INK4b in undifferentiated mouse skin tumors. Cancer Res. 55, 5168-5172 (1995)
23. Land, H., L.F. Parada & R.A. Weinberg: Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes. Nature 304, 596-602 (1983)
24. Stevenson, M. & D.J. Volsky: Activated v-myc and v-ras do not transform normal human lymphocytes. Mol. Cell. Biol. 6, 3410-3417 (1986)
25. Elenbaas, B., L. Spirio, F. Koerner, M.D. Fleming, D.B. Zimonjic, J.L. Donaher, N.C. Popescu, W.C. Hahn & R.A. Weinberg: Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells. Genes Dev. 15, 50-65 (2001)
26. Goytosolo, F.A. & M.A. Blasco: Many ways to telomere dysfunction: in vivo studies using mouse models. Oncogene 21, 584-591 (2002)
27. Le, S., J. Jiguang, D.C. Anthony, C.W. Greider & P. McL. Black: Telomerase activity in human gliomas. Neurosurgery 42, 1120-1125 (1998)
28. Bodnar, A.C., M. Ouellette, M. Frolkis, S.E. Holt, C.-P. Chiu, G.B. Morin, C.B. Harley, J.W. Shay, S. Lichtsteiner & W.E. Wright: Extension of life-span by introduction of telomerase into normal human cells. Science 279, 349-352 (1998)
29. Wright, W.E. & J.W. Shay: Telomere dynamics in cancer progression and prevention: fundamental differences in human and mouse telomere biology. Nature Medicine 6, 849-851 (2000)
30. Artandi, S.E. & R.A. DePinho: Mice without telomerase: what can they teach us about human cancer? . Nature Medicine 6, 852-855 (2000)
31. Drayton, S. & G. Peters: Immortalisation and transformation revisited. Curr. Opin. Genet. Dev. 12, 98-104 (2002)
32. Stewart, S.A. & R.A. Weinberg: Senescence: does it all happen at the ends? Oncogene 21, 627-630 (2002)
33. Yahanda, A.M., J.M. Bruner, L.A. Donehower & R.S. Morrison: Astrocytes derived from p53-deficient mice provide a multistep in vitro model for development of malignant glioma. Mol. Cell. Biol. 15, 4249-4259 (1995)
34. Holland, E.C., W.P. Hively, V. Gallo & H.E. Varmus: Modeling mutations in the G1 arrest pathway in human gliomas: overexpression of CDK4 but not loss of INK4a-ARF induces hyperploidy in cultured mouse astrocytes. Genes and Dev. 12, 3644-3649 (1998)
35. Artandi, S.E., S. Chang, S.L. Lee, S. Alson, G.J. Gottleib, L. Chin & R.A. DePinho: Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice. Nature 406, 641-645 (2000)
36. Gage, F.H. Mammalian neural stem cells. Science 287, 1433-1438 (2000)
37. Doetsch, F., I. Caille, D.A. Lim, J.M. Garcia-Verdugo & A. Alvarez-Buylla: Cell 97, 703-716 (1999)
38. Rietze, R.L., H. Valcanis, G.F. Brooker, T. Thomas, A.K. Voss & P.F. Bartlett: Purification of a pluripotent neural stem cell from the adult mouse brain. Nature 408, 686-689 (2001)
39. Danks, R.A., J.M.,Orian, M.F. Gonzales, S.S. Tan, B. Alexander, K. Mikoshiba & A.H. Kaye: Transformation of astrocytes in transgenic mice expressing SV40 T antigen under the transcriptional control of the glial fibrillary acidic protein promoter. Cancer Res. 55, 4302-4310 (1995)
40. Ding, H., L. Roncari, P. Shannon, X. Wu, N. Lau, J. Karaskova, D.H. Gutman, J.A. Squire, A. Nagy & A. Guha: Astrocyte-specific expression of activated p21-ras results in malignant astrocytoma formation in a transgenic mouse model of human gliomas. Cancer Res. 61, 3826-3836 (2001)
41. Hodgson G, J.H. Hager, S. Volik, S. Hariono, M. Wernick, D. Moore, N. Nowak, D.G. Albertson, D. Pinkel, C. Collins, D. Hanahan & J.W. Gray: Genome scanning with array CGH delineates regional alterations in mouse islet carcinomas. Nat Genet 29, 459-64 (2001)
42. Bunz, F., C. Fauth, M.R. Speicher, A. Dutriaux, J.M. Sedivy, K.W. Kinzler, B. Vogelstein & C. Lengauer: Targeted inactivation of p53 in human cells does not result in aneuploidy. Cancer Res. 62, 1129-1133 (2002)
43. Kondo, S., T. Morimura, G.H.Barnett, Y. Kondo, J.W. Peterson, R. Kaakaji, J. Takeuchi, S.A. Toms, J. Liu, B. Werbel & B.P Barna ; The transforming activities of MDM2 in cultured neonatal rat astrocytes. Oncogene 13, 1773-1779 (1996)
44. Dai, C., J.C. Celestino, Y. Okada, D.N. Louis, G.N. Fuller & E.C. Holland: PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo. Genes Dev. 15, 1913-25 (2001).
45. Holland, E.C., J. Celestino, C. Dai, L. Schaefer, R.E. Sawaya & G.N. Fuller: Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice. Nat. Genet. 25, 55-57 (2000)
46. Jacks, T., A. Fazeli, E. Schmitt, R. Bronson, M. Goodell & R.A. Weinberg: Effects of an Rb mutation in the mouse. Nature 359, 295-300 (1992)
47. Serrano, M., H. Lee, L. Chin, C. Cordon-Cardo, D. Beach & R.A. DePinho: Role of the INK4a locus in tumor suppression and cell mortality. Cell 85, 27-37 (1996)
48. Holland, E.C., W.P. Hively, R.A. DePinho & H.E. Varmus: A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice. Genes Dev. 12, 3675-3685 (1998)
49. Kamijo, T, S. Bodner, E. van de Kamp, D.H. Randle & C.J. Sherr: Tumor spectrum in ARF-deficient mice. Cancer Res. 59, 2217-2222 (1999)
50. Fanton, C.P., M. McMahon, M & R.O. Pieper: Dual growth arrest pathways in astrocytes and astrocytic tumors in response to raf-1 activation. J. Biol. Chem. 276: 19746-19753 (2001)
51. Vojtek, A.B. & C.J. Der: Increasing complexity of the Ras signaling pathway. J. Biol. Chem. 273, 19925-19928 (1998)
52. Hackel, P.O., E. Zwick, N. Prenzel & A. Ulrich: Epidermal growth factor receptors: critical mediators of multiple receptor pathways. Curr. Opin. Cell Biol. 11, 184-189 (1999)
53. Hamad, N.M., J.H. Elconin, A.E. Karnoub, W. Bai, J.N. Rich, R.T. Abraham, C.J. Der & C.M. Counter: Distinct requirements for Ras oncogenesis in human versus mouse cells. Genes Dev. 16, 2045-57 (2002)
54. Reilly, K.M., D.A. Loisel, R.T. Bronson, M.E. McLaughlin & T. Jacks: Nf1; Trp53 mutant mice develop glioblastoma with evidence of strain-specific effects. Nat. Genet. 26: 109-113 (2000)
55. Kanamori, M., Y. Sonoda, T. Ozawa, D.F. Deen,, S.-Y. Cheng & R.O. Pieper: Over-expression of VEGF isoforms drives oxygenation and growth, but not progression to glioblastoma multiforme in a human model of gliomagenesis. (submitted, Cancer Res.)