메뉴 건너뛰기




Volumn 54, Issue 2, 2001, Pages 218-231

Cellular and molecular biology of atherosclerotic lesions;Biología celular y molecular de las lesiones ateroscleróticas

Author keywords

Atherosclerosis; Low density lipoproteins (LDL); Macrophages; Smooth muscle cells (CML)

Indexed keywords

LOW DENSITY LIPOPROTEIN;

EID: 0037479386     PISSN: 03008932     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0300-8932(01)76294-x     Document Type: Article
Times cited : (25)

References (107)
  • 1
    • 0026541706 scopus 로고
    • The pathogenesis of coronary artery disease and the acute coronary syndromes (Part I)
    • Fuster V, Badimon L, Badimon JJ, Chesebro JH. The pathogenesis of coronary artery disease and the acute coronary syndromes (Part I). N Engl J Med 1992; 326: 242-250.
    • (1992) N Engl J Med , vol.326 , pp. 242-250
    • Fuster, V.1    Badimon, L.2    Badimon, J.J.3    Chesebro, J.H.4
  • 2
    • 0027125530 scopus 로고
    • The pathogenesis of coronary artery disease and the acute coronary syndromes (Part II)
    • Fuster V, Badimon L, Badimon JJ, Chesebro JH. The pathogenesis of coronary artery disease and the acute coronary syndromes (Part II). N Engl J Med 1992; 326: 310-318.
    • (1992) N Engl J Med , vol.326 , pp. 310-318
    • Fuster, V.1    Badimon, L.2    Badimon, J.J.3    Chesebro, J.H.4
  • 3
    • 0020972414 scopus 로고
    • Lipoprotein metabolism in the macrophage: Implications for cholesterol deposition in atherosclerosis
    • Brown MS, Goldstein JL. Lipoprotein metabolism in the macrophage: implications for cholesterol deposition in atherosclerosis. Annu Rev Biochem 1983; 52: 223-261.
    • (1983) Annu Rev Biochem , vol.52 , pp. 223-261
    • Brown, M.S.1    Goldstein, J.L.2
  • 4
    • 0027241856 scopus 로고
    • The pathogenesis of atherosclerosis: A perspective for the 1990s
    • Ros R. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 1993; 362: 801-808.
    • (1993) Nature , vol.362 , pp. 801-808
    • Ros, R.1
  • 5
    • 0026469540 scopus 로고
    • Thrombus formation on ruptured atherosclerotic plaques and rethrombosis on evolving thrombi
    • Badimon L, Chesebro JH, Badimon JJ. Thrombus formation on ruptured atherosclerotic plaques and rethrombosis on evolving thrombi. Circulation 1992; 86 (Supl III): 74-85.
    • (1992) Circulation , vol.86 , Issue.3 SUPL. , pp. 74-85
    • Badimon, L.1    Chesebro, J.H.2    Badimon, J.J.3
  • 6
    • 0027987849 scopus 로고
    • Randomised trial of cholesterol lowering in 4444 patiens with coronary heart disease: Scandinavian Simvastatin Survival Study (4S)
    • Group SSSS. Randomised trial of cholesterol lowering in 4444 patiens with coronary heart disease: Scandinavian Simvastatin Survival Study (4S). Lancet 1994; 344: 1383-1389.
    • (1994) Lancet , vol.344 , pp. 1383-1389
  • 8
    • 0342981862 scopus 로고    scopus 로고
    • The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels
    • Sacks FM, Pfeffer MA, Moye LA, Rouleau JL, Rutherford JD, Cole TG et al, for the Cholesterol and recurrent Events Trial Investigators. The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. N Engl J Med 1996; 335: 1001-1009.
    • (1996) N Engl J Med , vol.335 , pp. 1001-1009
    • Sacks, F.M.1    Pfeffer, M.A.2    Moye, L.A.3    Rouleau, J.L.4    Rutherford, J.D.5    Cole, T.G.6
  • 9
    • 0032487931 scopus 로고    scopus 로고
    • Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels
    • The Long-term Intervention with Pravastatin in Patients with Ischaemic Disease (LIPID) Study Group. Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. N Engl J Med 1998; 339: 1349-1357.
    • (1998) N Engl J Med , vol.339 , pp. 1349-1357
  • 10
    • 0032572086 scopus 로고    scopus 로고
    • Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: Results of AFCAPS/TexCAPS. Air Force/Texas Coronary Atherosclerosis prevention Study
    • Downs JR, Clearfield M, Weis S, Whitney E, Shapiro DR, Beere PA et al. Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPS/TexCAPS. Air Force/Texas Coronary Atherosclerosis prevention Study. JAMA 1998; 279: 1615-1622.
    • (1998) JAMA , vol.279 , pp. 1615-1622
    • Downs, J.R.1    Clearfield, M.2    Weis, S.3    Whitney, E.4    Shapiro, D.R.5    Beere, P.A.6
  • 11
    • 0025965439 scopus 로고
    • Modulation of coronary vasomotor tone in humans. Progressive endothelial dysfunction with different early stages of coronary atherosclerosis
    • Zeiher AM, Drexler H, Wollschlager H, Just H. Modulation of coronary vasomotor tone in humans. Progressive endothelial dysfunction with different early stages of coronary atherosclerosis. Circulation 1991; 83: 391-401.
    • (1991) Circulation , vol.83 , pp. 391-401
    • Zeiher, A.M.1    Drexler, H.2    Wollschlager, H.3    Just, H.4
  • 12
    • 0025896795 scopus 로고
    • Endothelial expression of a mononuclear leukocyte adhesion molecule during atherosclerosis
    • Cybulsky MI, Gimbrone MA Jr. Endothelial expression of a mononuclear leukocyte adhesion molecule during atherosclerosis. Science 1991; 251: 788-791.
    • (1991) Science , vol.251 , pp. 788-791
    • Cybulsky, M.I.1    Gimbrone M.A., Jr.2
  • 13
    • 0025334538 scopus 로고
    • Atherogenic concentrations of low-density lipoprotein enhance endothelial cell generation of epoxyeicosatrienoic acid products
    • Pritchard KA Jr, Wong PY, Stemerman MB. Atherogenic concentrations of low-density lipoprotein enhance endothelial cell generation of epoxyeicosatrienoic acid products. Am J Pathol 1990; 136: 1383-1391.
    • (1990) Am J Pathol , vol.136 , pp. 1383-1391
    • Pritchard K.A., Jr.1    Wong, P.Y.2    Stemerman, M.B.3
  • 14
    • 0032521624 scopus 로고    scopus 로고
    • Atherogenic concentrations of native low-density lipoproteins down-regulate nitric-oxide-synthase mRNA and protein levels in endothelial cells
    • Vidal F, Colomé C, Martínez-González J, Badimon L. Atherogenic concentrations of native low-density lipoproteins down-regulate nitric-oxide-synthase mRNA and protein levels in endothelial cells. Eur J Biochem 1998; 252: 378-384.
    • (1998) Eur J Biochem , vol.252 , pp. 378-384
    • Vidal, F.1    Colomé, C.2    Martínez-González, J.3    Badimon, L.4
  • 15
    • 0029133481 scopus 로고
    • Native low-density lipoprotein increases endothelial cell nitric oxide synthase generation of superoxide anion
    • Pritchard KA Jr, Groszek L, Smalley DM, Sessa WC, Wu M, Villalon P et al. Native low-density lipoprotein increases endothelial cell nitric oxide synthase generation of superoxide anion. Circ Res 1995; 77: 510-518.
    • (1995) Circ Res , vol.77 , pp. 510-518
    • Pritchard K.A., Jr.1    Groszek, L.2    Smalley, D.M.3    Sessa, W.C.4    Wu, M.5    Villalon, P.6
  • 17
    • 0026648108 scopus 로고
    • Elevated expression of monocyte chemoattractant protein 1 by vascular smooth muscle cells in hypercholesterolemic primates
    • Yu X, Dluz S, Graves DT, Zhang L, Antoniades HN, Hollander W et al. Elevated expression of monocyte chemoattractant protein 1 by vascular smooth muscle cells in hypercholesterolemic primates. Proc Natl Acad Sci USA 1992; 89: 6953-6957.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 6953-6957
    • Yu, X.1    Dluz, S.2    Graves, D.T.3    Zhang, L.4    Antoniades, H.N.5    Hollander, W.6
  • 18
    • 0023242333 scopus 로고
    • Increased growth stimulation of human vascular cells by serum from patients with primary hyper-LDL-cholesterolemia
    • Koschinsky T, Bunting CE, Rütter R, Gries FA. Increased growth stimulation of human vascular cells by serum from patients with primary hyper-LDL-cholesterolemia. Atherosclerosis 1987; 63: 7-13.
    • (1987) Atherosclerosis , vol.63 , pp. 7-13
    • Koschinsky, T.1    Bunting, C.E.2    Rütter, R.3    Gries, F.A.4
  • 19
    • 0031469791 scopus 로고    scopus 로고
    • Monounsatured and polyunsatured n-6 fatty acid-enriched diets modify LDL oxidation and decrease human coronary smooth muscle cell DNA synthesis
    • Mata P, Varela O, Lahoz C, Alonso R. de Hoya M, Badimon L. Monounsatured and polyunsatured n-6 fatty acid-enriched diets modify LDL oxidation and decrease human coronary smooth muscle cell DNA synthesis. Arterioscler Thromb Vasc Biol 1997; 17: 2088-2096.
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 2088-2096
    • Mata, P.1    Varela, O.2    Lahoz, C.3    Alonso, R.4    De Hoya, M.5    Badimon, L.6
  • 21
    • 0021904242 scopus 로고
    • Properties of lipoprotein complexes isolated by affinity chromatography from human aorta
    • Camejo G, Hurt E, Romano M. Properties of lipoprotein complexes isolated by affinity chromatography from human aorta. Biochem Biophys Acta 1985; 44: 389-401.
    • (1985) Biochem Biophys Acta , vol.44 , pp. 389-401
    • Camejo, G.1    Hurt, E.2    Romano, M.3
  • 22
    • 0031048299 scopus 로고    scopus 로고
    • Conner memorial lecture. Oxidative modification of LDL and atherogenesis
    • Steinberg D, Lewis A. Conner memorial lecture. Oxidative modification of LDL and atherogenesis. Circulation 1997; 95: 1062-1071.
    • (1997) Circulation , vol.95 , pp. 1062-1071
    • Steinberg, D.1    Lewis, A.2
  • 24
    • 17544403913 scopus 로고    scopus 로고
    • Small oxidative changes in atherogenic LDL concentrations irreversiblely regulate adhesiveness of human endothelial cells. Effect of the lazaroid U74500A
    • Colomé C, Martínez-González J, Vidal F, De Castellarnau C, Badimon L. Small oxidative changes in atherogenic LDL concentrations irreversiblely regulate adhesiveness of human endothelial cells. Effect of the lazaroid U74500A. Atherosclerosis 2000; 149: 295-302.
    • (2000) Atherosclerosis , vol.149 , pp. 295-302
    • Colomé, C.1    Martínez-González, J.2    Vidal, F.3    De Castellarnau, C.4    Badimon, L.5
  • 25
    • 0028292033 scopus 로고
    • Myeloperoxidase, a catalyst for lipoprotein oxidation, is expresed in human atherosclerotic lesions
    • Daugherty A, Dunn JL, Rateri DL, Heinecke JW. Myeloperoxidase, a catalyst for lipoprotein oxidation, is expresed in human atherosclerotic lesions. J Clin Invest 1994; 94: 437-444.
    • (1994) J Clin Invest , vol.94 , pp. 437-444
    • Daugherty, A.1    Dunn, J.L.2    Rateri, D.L.3    Heinecke, J.W.4
  • 26
    • 0027978458 scopus 로고
    • Pathophysiological concentrations of glucose promote oxidative modification of low density lipoprotein by a superoxide-dependent pathway
    • Kawamura M, Heinecke JW, Chait A. Pathophysiological concentrations of glucose promote oxidative modification of low density lipoprotein by a superoxide-dependent pathway. J Clin Invest 1994; 94: 771-778.
    • (1994) J Clin Invest , vol.94 , pp. 771-778
    • Kawamura, M.1    Heinecke, J.W.2    Chait, A.3
  • 27
    • 0026325498 scopus 로고
    • Monocyte transmigration induced by modification of low density lipoprotein in cocultures of human aortic wall cells is due to induction of monocyte chemotactic protein I synthesis and is abolish by high density lipoprotein
    • Navab M, Imes SS, Hama SY. Monocyte transmigration induced by modification of low density lipoprotein in cocultures of human aortic wall cells is due to induction of monocyte chemotactic protein I synthesis and is abolish by high density lipoprotein. J Clin Invest 1991; 88: 2039-2046.
    • (1991) J Clin Invest , vol.88 , pp. 2039-2046
    • Navab, M.1    Imes, S.S.2    Hama, S.Y.3
  • 29
    • 0032211819 scopus 로고    scopus 로고
    • Oxidized LDL activates Fas-mediated endothelial cell apoptosis
    • Sata M, Walsh K. Oxidized LDL activates Fas-mediated endothelial cell apoptosis. J Clin Invest 1998; 102: 1682-1689.
    • (1998) J Clin Invest , vol.102 , pp. 1682-1689
    • Sata, M.1    Walsh, K.2
  • 30
    • 0028821643 scopus 로고
    • Oxidized low-density lipoprotein decreases the expression of endothelial nitric oxide synthase
    • Liao JK, Shin WS, Lee WY, Clark SL. Oxidized low-density lipoprotein decreases the expression of endothelial nitric oxide synthase. J Biol Chem 1995; 270: 319-324.
    • (1995) J Biol Chem , vol.270 , pp. 319-324
    • Liao, J.K.1    Shin, W.S.2    Lee, W.Y.3    Clark, S.L.4
  • 31
    • 0033594968 scopus 로고    scopus 로고
    • Expression of lectinlike oxidized low-density lipoprotein receptor-1 in human atherosclerotic lesions
    • Kataoka H, Kume N, Miyamoto S, Minami M, Monwaki H, Murase T et al. Expression of lectinlike oxidized low-density lipoprotein receptor-1 in human atherosclerotic lesions. Circulation 1999; 99: 3110-3117.
    • (1999) Circulation , vol.99 , pp. 3110-3117
    • Kataoka, H.1    Kume, N.2    Miyamoto, S.3    Minami, M.4    Monwaki, H.5    Murase, T.6
  • 32
    • 13344261982 scopus 로고    scopus 로고
    • Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion
    • Brand K, Page S, Rogler G, Bartsch A, Brandl R, Knuechel R et al. Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion. J Clin Invest 1996; 97: 1715-1722.
    • (1996) J Clin Invest , vol.97 , pp. 1715-1722
    • Brand, K.1    Page, S.2    Rogler, G.3    Bartsch, A.4    Brandl, R.5    Knuechel, R.6
  • 34
    • 0028174061 scopus 로고
    • Function and activation of NFkB in the immune system
    • Baeuerle PA, Henkel T. Function and activation of NFkB in the immune system. Annu Rev Immunol 1994; 12: 141-179.
    • (1994) Annu Rev Immunol , vol.12 , pp. 141-179
    • Baeuerle, P.A.1    Henkel, T.2
  • 35
    • 0028986193 scopus 로고
    • NF-kB: A lesson in family values
    • Thanos D, Maniatis T. NF-kB: a lesson in family values. Cell 1995; 80: 529-532.
    • (1995) Cell , vol.80 , pp. 529-532
    • Thanos, D.1    Maniatis, T.2
  • 36
    • 0030916179 scopus 로고    scopus 로고
    • The nuclear factor k-B signaling pathway participates in dysiegulation of vascular smooth muscle cells in vitro and in human atherosclerois
    • Bourcier T, Sukhova G, Libby P. The nuclear factor k-B signaling pathway participates in dysiegulation of vascular smooth muscle cells in vitro and in human atherosclerois. J Biol Chem 1997; 272: 15817-15824.
    • (1997) J Biol Chem , vol.272 , pp. 15817-15824
    • Bourcier, T.1    Sukhova, G.2    Libby, P.3
  • 37
    • 0032573018 scopus 로고    scopus 로고
    • Nuclear factor-kB is selectively and markedly activated in humans with unstable angina pectoris
    • Ritchie ME. Nuclear factor-kB is selectively and markedly activated in humans with unstable angina pectoris. Circulation 1998; 98: 1707-1713.
    • (1998) Circulation , vol.98 , pp. 1707-1713
    • Ritchie, M.E.1
  • 38
    • 0018398906 scopus 로고
    • Arachidonic acid metabolites and the interactions between platelets and blood-vessel walls
    • Moncada S, Vane JR. Arachidonic acid metabolites and the interactions between platelets and blood-vessel walls. N Engl J Med 1979; 300: 1142-1147.
    • (1979) N Engl J Med , vol.300 , pp. 1142-1147
    • Moncada, S.1    Vane, J.R.2
  • 39
    • 0025847743 scopus 로고
    • Glycosaminoglycans, molecular properties, protein interactions and role in physiological processes
    • Jackson RL, Busch SJ, Cardin AD. Glycosaminoglycans, molecular properties, protein interactions and role in physiological processes. Physiol Rev 1991; 71: 481-539.
    • (1991) Physiol Rev , vol.71 , pp. 481-539
    • Jackson, R.L.1    Busch, S.J.2    Cardin, A.D.3
  • 40
    • 0032521624 scopus 로고    scopus 로고
    • Atherogenic concentrations of native low density lipoproteins modulates niric oxide synthase gene expression in endothelial cells
    • Vidal F, Colomé C, Martínez-González J, Badimon L. Atherogenic concentrations of native low density lipoproteins modulates niric oxide synthase gene expression in endothelial cells. Eur J Biochem 1998; 252: 374-384.
    • (1998) Eur J Biochem , vol.252 , pp. 374-384
    • Vidal, F.1    Colomé, C.2    Martínez-González, J.3    Badimon, L.4
  • 42
    • 0029143965 scopus 로고
    • Increased soluble form of P-selectin in patients with unstable angina
    • Ikeda H, Takajo Y, Ichiki K, Ueno T, Maki S, Noda T et al. Increased soluble form of P-selectin in patients with unstable angina. Circulation 1995; 92: 1693-1696.
    • (1995) Circulation , vol.92 , pp. 1693-1696
    • Ikeda, H.1    Takajo, Y.2    Ichiki, K.3    Ueno, T.4    Maki, S.5    Noda, T.6
  • 43
    • 0030665650 scopus 로고    scopus 로고
    • Soluble adhesion molecules reflect endothelial cell activation in ische;mic stroke and in carotid atherosclerosis
    • Frijns CJM, Kappelle LJ, Van Gijn J, Nieuwenhuis HK, Sixma JJ, Fijnheer R. Soluble adhesion molecules reflect endothelial cell activation in ische;mic stroke and in carotid atherosclerosis. Stroke 1997; 28: 2214-2218.
    • (1997) Stroke , vol.28 , pp. 2214-2218
    • Frijns, C.J.M.1    Kappelle, L.J.2    Van Gijn, J.3    Nieuwenhuis, H.K.4    Sixma, J.J.5    Fijnheer, R.6
  • 44
    • 0028092958 scopus 로고
    • Nitric oxide synthase: Roles, tolls and controls
    • Nathan C, Xie QW. Nitric oxide synthase: roles, tolls and controls. Cell 1994; 78: 915-918.
    • (1994) Cell , vol.78 , pp. 915-918
    • Nathan, C.1    Xie, Q.W.2
  • 45
    • 0032167652 scopus 로고    scopus 로고
    • Local adenovirus-mediated transfer of endothelial nitric oxide synthase reduces luminal narrowing after coronary angioplasty in pigs
    • Varenne O, Pislaru S, Gillijns H, Pelt NV, Gerard RD, Zoldhelyi P et al. Local adenovirus-mediated transfer of endothelial nitric oxide synthase reduces luminal narrowing after coronary angioplasty in pigs. Circulation 1998; 98: 919-926.
    • (1998) Circulation , vol.98 , pp. 919-926
    • Varenne, O.1    Pislaru, S.2    Gillijns, H.3    Pelt, N.V.4    Gerard, R.D.5    Zoldhelyi, P.6
  • 47
    • 0033535841 scopus 로고    scopus 로고
    • -786 → C mutation in the 5′-flanking region of the endothelial nitric oxide synthase gene is associated with coronary spasm
    • -786 → C mutation in the 5′-flanking region of the endothelial nitric oxide synthase gene is associated with coronary spasm. Circulation 1999; 99: 2864-2870.
    • (1999) Circulation , vol.99 , pp. 2864-2870
    • Nakayama, M.1    Yasue, H.2    Yoshimura, M.3    Shimasaki, Y.4    Kugiyama, K.5    Ogawa, H.6
  • 48
    • 0028100605 scopus 로고
    • Indirect angiogenic cytokines upregulate VEGF and bFGF gene expression in vascular smooth muscle cells, whereas hypoxia upregulates VEGF expression only
    • Brogi E, Wu T, Namiki A, Isner JM. Indirect angiogenic cytokines upregulate VEGF and bFGF gene expression in vascular smooth muscle cells, whereas hypoxia upregulates VEGF expression only. Circulation 1994; 90; 649-652.
    • (1994) Circulation , vol.90 , pp. 649-652
    • Brogi, E.1    Wu, T.2    Namiki, A.3    Isner, J.M.4
  • 49
    • 0030835742 scopus 로고    scopus 로고
    • Atherosclerosis as a microvascular disease: Impaired angiogenesis mediated by suppressed basic fibroblast growth factor expression
    • Chen CH, Henry PD. Atherosclerosis as a microvascular disease: impaired angiogenesis mediated by suppressed basic fibroblast growth factor expression. Proc Assoc Am Physicians 1997; 109: 351-361.
    • (1997) Proc Assoc Am Physicians , vol.109 , pp. 351-361
    • Chen, C.H.1    Henry, P.D.2
  • 50
    • 0032542072 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) expression in human coronary atherosclerotic lesions. Possible pathophysiological significance of VEGF in progression of atherosclerosis
    • Inoue M, Itoh H, Ueda M, Naruko T, Kojima A, Komatsu R et al. Vascular endothelial growth factor (VEGF) expression in human coronary atherosclerotic lesions. Possible pathophysiological significance of VEGF in progression of atherosclerosis. Circulation 1998; 98: 2108-2116.
    • (1998) Circulation , vol.98 , pp. 2108-2116
    • Inoue, M.1    Itoh, H.2    Ueda, M.3    Naruko, T.4    Kojima, A.5    Komatsu, R.6
  • 51
    • 0032989856 scopus 로고    scopus 로고
    • Co-operation between endothelium and nitric oxide in promoting endothelial cell migration and angiogenesis
    • Goligorsky MS, Budzikowski AS, Tsukahara h, Noiri E. Co-operation between endothelium and nitric oxide in promoting endothelial cell migration and angiogenesis. Clin Exp Pharmacol Physiol 1999; 26: 269-271.
    • (1999) Clin Exp Pharmacol Physiol , vol.26 , pp. 269-271
    • Goligorsky, M.S.1    Budzikowski, A.S.2    Tsukahara, H.3    Noiri, E.4
  • 52
    • 0028027007 scopus 로고
    • Thrombin induces endothelial cell growth via both a proteolitic and a non-proteolitic pathway
    • Herbert JM, Dupuy E, Laplace MC, Zini J-M, Bar-Shavit R, Toberlem G. Thrombin induces endothelial cell growth via both a proteolitic and a non-proteolitic pathway. Biochem J 1994; 303: 227-231.
    • (1994) Biochem J , vol.303 , pp. 227-231
    • Herbert, J.M.1    Dupuy, E.2    Laplace, M.C.3    Zini, J.-M.4    Bar-Shavit, R.5    Toberlem, G.6
  • 53
    • 0031458301 scopus 로고    scopus 로고
    • Thrombin receptor-mediated increase of two matrix metalloproteinases, MMP-1 and MMP-3, in human endothelial cells
    • Duhamel-Clérin E, Orvain C, Lanza F, Cazenave JP, Klein-Soyer C. Thrombin receptor-mediated increase of two matrix metalloproteinases, MMP-1 and MMP-3, in human endothelial cells. Arterioscler Thromb Vas Biol 1997; 17: 1931-1938.
    • (1997) Arterioscler Thromb Vas Biol , vol.17 , pp. 1931-1938
    • Duhamel-Clérin, E.1    Orvain, C.2    Lanza, F.3    Cazenave, J.P.4    Klein-Soyer, C.5
  • 55
    • 0029097154 scopus 로고
    • A definition of advances types of atherosclerotic lesions and a histological classification of atherosclerosis: A report from the committee on vascular lesions of the Council on Arteriosclerosis, American Heart Association
    • Stary HC, Chandler AB, Dinsmore RE, Fuster V, Glasgov S, Insull W et al. A definition of advances types of atherosclerotic lesions and a histological classification of atherosclerosis: a report from the committee on vascular lesions of the Council on Arteriosclerosis, American Heart Association. Circulation 1995; 92: 1355-1374.
    • (1995) Circulation , vol.92 , pp. 1355-1374
    • Stary, H.C.1    Chandler, A.B.2    Dinsmore, R.E.3    Fuster, V.4    Glasgov, S.5    Insull, W.6
  • 57
    • 0032890453 scopus 로고    scopus 로고
    • Macrophage released proteoglycans are involved in cell-mediated aggregation of LDL
    • Maor I, Aviram M. Macrophage released proteoglycans are involved in cell-mediated aggregation of LDL. Atherosclerosis 1999; 142: 57-66.
    • (1999) Atherosclerosis , vol.142 , pp. 57-66
    • Maor, I.1    Aviram, M.2
  • 58
    • 0026323061 scopus 로고
    • Phagocytosis of lipase agreggated low density lipoprotein promotes macrophage foam cell formation: Sequencial morphological and biochemical events
    • Heinecke JW, Suits A, Aviram M, Chait A. Phagocytosis of lipase agreggated low density lipoprotein promotes macrophage foam cell formation: sequencial morphological and biochemical events. Arterioscler Thromb 1991; 11: 1643-1651.
    • (1991) Arterioscler Thromb , vol.11 , pp. 1643-1651
    • Heinecke, J.W.1    Suits, A.2    Aviram, M.3    Chait, A.4
  • 59
    • 9544244765 scopus 로고    scopus 로고
    • Macrophages stimulate cholesteryl ester accumulation in cocultured smooth muscle cells incubated with lipoprotein-proteoglycan complex
    • Vijayagopal P, Glancy L. Macrophages stimulate cholesteryl ester accumulation in cocultured smooth muscle cells incubated with lipoprotein-proteoglycan complex. Arterioscler Thromb Vasc Biol 1996; 16: 1112-1121.
    • (1996) Arterioscler Thromb Vasc Biol , vol.16 , pp. 1112-1121
    • Vijayagopal, P.1    Glancy, L.2
  • 60
    • 0028267404 scopus 로고
    • Macrophage scavenger receptors
    • Freeman MW. Macrophage scavenger receptors. Curr Opin Lipid 1994; 5: 143-148.
    • (1994) Curr Opin Lipid , vol.5 , pp. 143-148
    • Freeman, M.W.1
  • 61
    • 0027956982 scopus 로고
    • Modification of low density lipoprotein by advances glycation end products contributes to the dyslipidemia of diabetes and renal insuficiency
    • Bucala R, Makita Z, Vega G, Grundy S, Koschinsky T, Cerami A et al. Modification of low density lipoprotein by advances glycation end products contributes to the dyslipidemia of diabetes and renal insuficiency. Proc Natl Acad Sci USA 1994; 91: 9441-9445.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 9441-9445
    • Bucala, R.1    Makita, Z.2    Vega, G.3    Grundy, S.4    Koschinsky, T.5    Cerami, A.6
  • 62
    • 0032562276 scopus 로고    scopus 로고
    • Expression of LDL receptor, VLDL receptor, LDL receptor-related protein, and scavenger receptor in rabbit atherosclerotic lessions
    • Timo PH, Luoma JS, Nikkari T, Ylä-Herttuala S. Expression of LDL receptor, VLDL receptor, LDL receptor-related protein, and scavenger receptor in rabbit atherosclerotic lessions. Circulation 1998; 97: 1079-1086.
    • (1998) Circulation , vol.97 , pp. 1079-1086
    • Timo, P.H.1    Luoma, J.S.2    Nikkari, T.3    Ylä-Herttuala, S.4
  • 63
    • 0028210044 scopus 로고
    • Expression of α2-macroglobulin receptor/low density lipoprotein receptor-related protein and scavenger receptor in human atherosclerotic lesions
    • Luoma J, Hiltunen T, Särkioja T, Moestrup SK, Gliemann J, Kodama T et al. Expression of α2-macroglobulin receptor/low density lipoprotein receptor-related protein and scavenger receptor in human atherosclerotic lesions. J Clin Invest 1994; 93: 2014-2021.
    • (1994) J Clin Invest , vol.93 , pp. 2014-2021
    • Luoma, J.1    Hiltunen, T.2    Särkioja, T.3    Moestrup, S.K.4    Gliemann, J.5    Kodama, T.6
  • 64
    • 0030024123 scopus 로고    scopus 로고
    • Development of the lipid-rich core in human atherosclerosis
    • Guyton JR, Klemp KF. Development of the lipid-rich core in human atherosclerosis. Arterioscler Thromb Vasc Biol 1996; 16: 4-11.
    • (1996) Arterioscler Thromb Vasc Biol , vol.16 , pp. 4-11
    • Guyton, J.R.1    Klemp, K.F.2
  • 65
    • 0029084524 scopus 로고
    • Human monocyte-derived macrophages induce collagen breakdown in fibrous caps of atherosclerotic plaques: Potential role of matrix-degrading metalloproteinases and implications for plaque rupture
    • Shah PK, Falk E, Badimon JJ, Fernández-Ortiz A, Mailhac A, Villareal-Levy G et al. Human monocyte-derived macrophages induce collagen breakdown in fibrous caps of atherosclerotic plaques: potential role of matrix-degrading metalloproteinases and implications for plaque rupture. Circulation 1995; 92: 1565-1569.
    • (1995) Circulation , vol.92 , pp. 1565-1569
    • Shah, P.K.1    Falk, E.2    Badimon, J.J.3    Fernández-Ortiz, A.4    Mailhac, A.5    Villareal-Levy, G.6
  • 66
    • 0029096288 scopus 로고
    • Elucidation of the role of plaque instability and rupture in acute coronay events
    • Fuster V. Elucidation of the role of plaque instability and rupture in acute coronay events. Am J Cardiol 1995; 76: 24C-33C.
    • (1995) Am J Cardiol , vol.76
    • Fuster, V.1
  • 67
    • 0033594811 scopus 로고    scopus 로고
    • Membrane type 1 matrix metalloproteinase expression in human atherosclerotic plaques
    • Rajavashisth TB, Xu XP, Jovinge S, Maisel S, Xu XO, Chai NN et al. Membrane type 1 matrix metalloproteinase expression in human atherosclerotic plaques. Circulation 1999; 99: 3103-3109.
    • (1999) Circulation , vol.99 , pp. 3103-3109
    • Rajavashisth, T.B.1    Xu, X.P.2    Jovinge, S.3    Maisel, S.4    Xu, X.O.5    Chai, N.N.6
  • 68
    • 0032560637 scopus 로고    scopus 로고
    • Lipid lowering by diet reduces matrix metalloproteinase activity and increases collagen content of rabbit atheroma: A potential mechanism of lesion stabilization
    • Aikawa M, Rabkin E, Okada Y, Voglic SJ, Clinton SK, Brinckerhoff CE et al. Lipid lowering by diet reduces matrix metalloproteinase activity and increases collagen content of rabbit atheroma: a potential mechanism of lesion stabilization. Circulation 1998; 97: 2433-2444.
    • (1998) Circulation , vol.97 , pp. 2433-2444
    • Aikawa, M.1    Rabkin, E.2    Okada, Y.3    Voglic, S.J.4    Clinton, S.K.5    Brinckerhoff, C.E.6
  • 69
    • 0032406276 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibition by atorvastatin reduces neointimal inflammation in a rabbit model of atherosclerosis
    • Bustos C, Hernández-Presa MA, Ortego M, Tuñón J, Ortega L, Pérez F et al. HMG-CoA reductase inhibition by atorvastatin reduces neointimal inflammation in a rabbit model of atherosclerosis. J Am Coll Cardiol 1998; 32: 2057-2064.
    • (1998) J Am Coll Cardiol , vol.32 , pp. 2057-2064
    • Bustos, C.1    Hernández-Presa, M.A.2    Ortego, M.3    Tuñón, J.4    Ortega, L.5    Pérez, F.6
  • 71
    • 0032963957 scopus 로고    scopus 로고
    • Effects of statins in thrombosis and aortic lesion development in a dyslipemic rabbit model
    • Alfon J, Palazón CP, Royo T, Badimon L. Effects of statins in thrombosis and aortic lesion development in a dyslipemic rabbit model. Thromb Haemost 1999; 81: 822-827.
    • (1999) Thromb Haemost , vol.81 , pp. 822-827
    • Alfon, J.1    Palazón, C.P.2    Royo, T.3    Badimon, L.4
  • 73
    • 0025697475 scopus 로고
    • The contribution of studies of atherosclerotic lesions in young people to future research
    • Wissler RW, Vesselinovitch D, Komatsu A. The contribution of studies of atherosclerotic lesions in young people to future research. Ann NY Acad Sci 1990; 598: 418-434.
    • (1990) Ann NY Acad Sci , vol.598 , pp. 418-434
    • Wissler, R.W.1    Vesselinovitch, D.2    Komatsu, A.3
  • 74
    • 0025281462 scopus 로고
    • Syndromes of accelerated atherosclerosis: Role of vascular injury and smooth muscle cell proliferation
    • Ip JH, Fuster V, Badimon L, Badimon JJ, Taubman MB, Chesebro JH. Syndromes of accelerated atherosclerosis: role of vascular injury and smooth muscle cell proliferation. J Am Coll Cardiol 1990; 15: 1667-1687.
    • (1990) J Am Coll Cardiol , vol.15 , pp. 1667-1687
    • Ip, J.H.1    Fuster, V.2    Badimon, L.3    Badimon, J.J.4    Taubman, M.B.5    Chesebro, J.H.6
  • 78
    • 0030685740 scopus 로고    scopus 로고
    • Inhibitory role of plasminogen activator inhibitor-1 in arterial wound healing and neointima formation: A gene targeting and gene transfer study in mice
    • Carmeliet P, Moons L, Lijnen R, Janssens S, Lupu F, Collen D et al. Inhibitory role of plasminogen activator inhibitor-1 in arterial wound healing and neointima formation: a gene targeting and gene transfer study in mice. Circulation 1997; 96: 3180-3191.
    • (1997) Circulation , vol.96 , pp. 3180-3191
    • Carmeliet, P.1    Moons, L.2    Lijnen, R.3    Janssens, S.4    Lupu, F.5    Collen, D.6
  • 79
    • 0030042886 scopus 로고    scopus 로고
    • Regulation of matrix metalloproteinases and plasminogen activator inhibitor-1 synthesis by plasminogen in cultured human vascular smooth muscle cells
    • Lee E, Vaughan DE, Parikh SH, Grodzinsky AJ, Libby P, Lark MW et al. Regulation of matrix metalloproteinases and plasminogen activator inhibitor-1 synthesis by plasminogen in cultured human vascular smooth muscle cells. Circ Res 1996; 78: 44-49.
    • (1996) Circ Res , vol.78 , pp. 44-49
    • Lee, E.1    Vaughan, D.E.2    Parikh, S.H.3    Grodzinsky, A.J.4    Libby, P.5    Lark, M.W.6
  • 80
    • 0027207192 scopus 로고
    • r-PDGF gene expression in porcine arteries induces intimal hyperplasia in vivo
    • Nabel EG, Liptay S, Yang ZY, Liptay S, San H, Gordon D et al. r-PDGF gene expression in porcine arteries induces intimal hyperplasia in vivo. J Clin Invest 1993; 91: 1822-1829.
    • (1993) J Clin Invest , vol.91 , pp. 1822-1829
    • Nabel, E.G.1    Liptay, S.2    Yang, Z.Y.3    Liptay, S.4    San, H.5    Gordon, D.6
  • 81
    • 0026418308 scopus 로고
    • Inhibition of neointimal smooth muscle accumulation after angioplasty by an antibody to PDGF
    • Ferns AA, Raines EW, Sprugel KH, Motani AS, Reidy MA, Ross R. Inhibition of neointimal smooth muscle accumulation after angioplasty by an antibody to PDGF. Science 1991; 253: 1129-1132.
    • (1991) Science , vol.253 , pp. 1129-1132
    • Ferns, A.A.1    Raines, E.W.2    Sprugel, K.H.3    Motani, A.S.4    Reidy, M.A.5    Ross, R.6
  • 83
    • 0031957515 scopus 로고    scopus 로고
    • The response of smooth muscle cells to a-thrombin depends on its arterial origin: Comparison among different species
    • Varela O, Martínez-González J, Badimon L. The response of smooth muscle cells to a-thrombin depends on its arterial origin: comparison among different species. Eur J Clin Invest 1998; 28: 313-323.
    • (1998) Eur J Clin Invest , vol.28 , pp. 313-323
    • Varela, O.1    Martínez-González, J.2    Badimon, L.3
  • 86
    • 0027281460 scopus 로고
    • Induction of vascular SMC expression of PAI-1 by thrombin
    • Noda H, Fuji S, Sobel B. Induction of vascular SMC expression of PAI-1 by thrombin. Circ Res 1993; 72: 36-43.
    • (1993) Circ Res , vol.72 , pp. 36-43
    • Noda, H.1    Fuji, S.2    Sobel, B.3
  • 87
    • 0027497117 scopus 로고
    • Direct gene transfer of TGF-β1 inthearterial wall stimulates fibrocellular hyperplasia
    • Nabel EG, Shum L, Pompili VJ, Yang Z-Y, San H, Shu HB et al. Direct gene transfer of TGF-β1 inthearterial wall stimulates fibrocellular hyperplasia. Proc Natl Acad Sci USA 1993; 90: 10759-10764.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 10759-10764
    • Nabel, E.G.1    Shum, L.2    Pompili, V.J.3    Yang, Z.-Y.4    San, H.5    Shu, H.B.6
  • 90
    • 0031469635 scopus 로고    scopus 로고
    • Thrombospondin-1 is a potent mitogen and chemoattractant for human vascular smooth muscle cells
    • Patel MK, Lymn JS, Clunn GF, Hughes AD. Thrombospondin-1 is a potent mitogen and chemoattractant for human vascular smooth muscle cells. Arterioscler Thromb Vasc Biol 1997; 17: 2107-2114.
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 2107-2114
    • Patel, M.K.1    Lymn, J.S.2    Clunn, G.F.3    Hughes, A.D.4
  • 91
    • 0026713221 scopus 로고
    • Expression of the c-myb proto-oncogene in bovine vascular smooth muscle cells
    • Brown KE, Kindy MS, Sonenshein GE. Expression of the c-myb proto-oncogene in bovine vascular smooth muscle cells. J Biol Chem 1992; 267: 4625-4630.
    • (1992) J Biol Chem , vol.267 , pp. 4625-4630
    • Brown, K.E.1    Kindy, M.S.2    Sonenshein, G.E.3
  • 93
    • 85031469922 scopus 로고    scopus 로고
    • A nuclear hormone receptor gene is up-regulated by thrombin in smooth muscle cells
    • Castello A, Cases C, Martínez-González J, Badimon L. A nuclear hormone receptor gene is up-regulated by thrombin in smooth muscle cells. Eur Heart J 1999; 30: 357.
    • (1999) Eur Heart J , vol.30 , pp. 357
    • Castello, A.1    Cases, C.2    Martínez-González, J.3    Badimon, L.4
  • 94
    • 0030029390 scopus 로고    scopus 로고
    • Antisense oligonucleotide to NOR-1, a novel orphan nuclear receptor, induces migration and neunte extension of cultured forebrain cells
    • Ohkura N, Hijikuro M, Miki K. Antisense oligonucleotide to NOR-1, a novel orphan nuclear receptor, induces migration and neunte extension of cultured forebrain cells. Mol Brain Res 1996; 35: 309-313.
    • (1996) Mol Brain Res , vol.35 , pp. 309-313
    • Ohkura, N.1    Hijikuro, M.2    Miki, K.3
  • 95
    • 0030977267 scopus 로고    scopus 로고
    • Functional redundancy of the Nur77 and Nor-1 orphan steroid receptors in T-cell apoptosis
    • Cheng LE, Chan FK, Cado D, Winoto A. Functional redundancy of the Nur77 and Nor-1 orphan steroid receptors in T-cell apoptosis. EMBO J 1997; 16: 1865-1875.
    • (1997) EMBO J , vol.16 , pp. 1865-1875
    • Cheng, L.E.1    Chan, F.K.2    Cado, D.3    Winoto, A.4
  • 96
    • 0028170817 scopus 로고
    • Receptor protein-tyrosine kinases and their signal transduction pathways
    • Van deer Gee P, Hunter T. Receptor protein-tyrosine kinases and their signal transduction pathways. Annu Rev Cell Biol 1994; 10: 251-337.
    • (1994) Annu Rev Cell Biol , vol.10 , pp. 251-337
    • Van Deer Gee, P.1    Hunter, T.2
  • 97
    • 0027165150 scopus 로고
    • The mitogenic-activated protein kinase signal transduction pathway
    • Davis R. The mitogenic-activated protein kinase signal transduction pathway. J Biol Chem 1993; 268: 14553-14556.
    • (1993) J Biol Chem , vol.268 , pp. 14553-14556
    • Davis, R.1
  • 98
    • 0033954603 scopus 로고    scopus 로고
    • Signalling via stress-activated mitogen-activated protein kinases in the cardiovascular system
    • Bogoyevitch MA. Signalling via stress-activated mitogen-activated protein kinases in the cardiovascular system. Caidiovasc Res 2000; 45: S26-842.
    • (2000) Caidiovasc Res , vol.45
    • Bogoyevitch, M.A.1
  • 99
    • 0026770875 scopus 로고
    • Three types of naturally ocurring modified lipoproteins induce intracellular lipid accumulation due to lipoprotein aggregation
    • Tertov VV, Orckhov AN, Sobenin ZA, Gabbasov A, Popov EG, Yaroslavov AA et al. Three types of naturally ocurring modified lipoproteins induce intracellular lipid accumulation due to lipoprotein aggregation. Circ Res 1992; 71: 218-228.
    • (1992) Circ Res , vol.71 , pp. 218-228
    • Tertov, V.V.1    Orckhov, A.N.2    Sobenin, Z.A.3    Gabbasov, A.4    Popov, E.G.5    Yaroslavov, A.A.6
  • 100
    • 0027257233 scopus 로고
    • Lipoprotein lipase and sphingomyelinase sinergistically enhance the association of atherogenic lipoproteins with smooth muscle cells and extracellular matrix
    • Tabas I, Yueqing L, Brocia RW, Wen Xu S, Swenson TL, Williams KJ. Lipoprotein lipase and sphingomyelinase sinergistically enhance the association of atherogenic lipoproteins with smooth muscle cells and extracellular matrix. J Biol Chem 1993; 268: 20-19-20432.
    • (1993) J Biol Chem , vol.268 , pp. 2019-20432
    • Tabas, I.1    Yueqing, L.2    Brocia, R.W.3    Wen Xu, S.4    Swenson, T.L.5    Williams, K.J.6
  • 101
    • 0026688830 scopus 로고
    • Platelet-derived growth factor induces c-fins and scavenger receptor genes in vascular smooth muscle cells
    • Inaba T, Gotoda T, Shimano H, Shimada M, Harda K, Kozaki K et al. Platelet-derived growth factor induces c-fins and scavenger receptor genes in vascular smooth muscle cells. J Biol Chem 1992; 267: 13107-13112.
    • (1992) J Biol Chem , vol.267 , pp. 13107-13112
    • Inaba, T.1    Gotoda, T.2    Shimano, H.3    Shimada, M.4    Harda, K.5    Kozaki, K.6
  • 102
    • 85031466684 scopus 로고    scopus 로고
    • Low density lipoprotein receptor-related protein mediates the uptake of aggregated low density lipoprotein in human vascular smooth muscle cells
    • en prensa.
    • Llorente-Cortés V, Martínez-González J, Badimon L. Low density lipoprotein receptor-related protein mediates the uptake of aggregated low density lipoprotein in human vascular smooth muscle cells. Arterioscler Thromb Vasc Biol 2000 (en prensa).
    • (2000) Arterioscler Thromb Vasc Biol
    • Llorente-Cortés, V.1    Martínez-González, J.2    Badimon, L.3
  • 103
    • 0031833783 scopus 로고    scopus 로고
    • Esterified cholesterol accumulation induced by aggregated LDL uptake in human vascular smooth muscle cells is reduced by HMG-CoA reductase inhibitors
    • Llorente-Cortés V, Martínez-González J, Badimon L. Esterified cholesterol accumulation induced by aggregated LDL uptake in human vascular smooth muscle cells is reduced by HMG-CoA reductase inhibitors. Arterioscler Thromb Vasc Biol 1998; 18: 738-746.
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 738-746
    • Llorente-Cortés, V.1    Martínez-González, J.2    Badimon, L.3
  • 104
    • 0025369190 scopus 로고
    • Proteolytic processing of the 600 Kd low density lipoprotein receptor-related protein (LRP) occurs in a trans-Golgi compartment
    • Herz J, Kowal RC, Goldslein JL, Brown MS. Proteolytic processing of the 600 Kd low density lipoprotein receptor-related protein (LRP) occurs in a trans-Golgi compartment. EMBO J 1988; 9: 1769-1776.
    • (1988) EMBO J , vol.9 , pp. 1769-1776
    • Herz, J.1    Kowal, R.C.2    Goldslein, J.L.3    Brown, M.S.4
  • 105
    • 0025732020 scopus 로고
    • Altered ultrastructural morphology of self-aggregated low density lipoproteins: Coalescence of lipid domains forming droplets and vesicles
    • Guyton JR, Klemp KF, Mims MP. Altered ultrastructural morphology of self-aggregated low density lipoproteins: coalescence of lipid domains forming droplets and vesicles. J Lipid Res 1991; 32: 953-961.
    • (1991) J Lipid Res , vol.32 , pp. 953-961
    • Guyton, J.R.1    Klemp, K.F.2    Mims, M.P.3
  • 107
    • 85031469485 scopus 로고    scopus 로고
    • Expression of low density lipoprotein receptor-related protein in human coronary atherosclerotic plaques
    • Berrozpe M, Llorente V, Badimon L. Expression of low density lipoprotein receptor-related protein in human coronary atherosclerotic plaques. Kardiovasckuläre Medizin 1999; 2: 75.
    • (1999) Kardiovasckuläre Medizin , vol.2 , pp. 75
    • Berrozpe, M.1    Llorente, V.2    Badimon, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.