HDL-induced prostacyclin release in smooth muscle cells is dependent on Cyclooxygeuase-2 (Cox-2)

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 17, Issue 12, 1997, Pages 3481-3488

  Vinals M ^a   Martinez Gonzalez J ^a   Badimon, J J ^b   Badimon, L ^a,c  

^a Institut Català de Ciències Cardiovasculars   (Spain)

^b MOUNT SINAI MEDICAL CENTER   (United States)

^c HOSPITAL DE LA SANTA CREU I SANT PAU   (Spain)

Author keywords

Cyclooxygenase 1; Cyclooxygenase 2; HDL; LDL; NS 398

Indexed keywords

CYCLOHEXIMIDE; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; DACTINOMYCIN; DEXAMETHASONE; HIGH DENSITY LIPOPROTEIN; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; PROSTACYCLIN DERIVATIVE; PROSTAGLANDIN SYNTHASE INHIBITOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATHEROSCLEROSIS; CONTROLLED STUDY; DNA PROBE; ENZYME IMMUNOASSAY; GENE EXPRESSION; IMMUNOBLOTTING; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; SMOOTH MUSCLE FIBER; SOUTHERN BLOTTING;

EID: 0031458496     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.17.12.3481     Document Type: Article

References (22)

1. Gordon T, Castelli WP, Hjortland MC, Kannel WB, Dawber TR. High density lipoproteins as a protective factor against coronary heart disease: the Framingham study. Am J Med. 1977;62:707-714.
2. Rhoads GG, Gulbrandse CL, Kagen A. Serum lipoprotein and coronary heart disease in a population study of Hawai Japanese men. N Engl J Med. 1977;294:293-298.
3. Barter P, Rye K. High density lipoproteins and coronary heart disease. Atherosclerosis. 1996;121:1-12.
4. Oram JF, Albers JJ, Cheung MC, Bierman EL. The effects of subfractions of high density lipoprotein on cholesterol efflux from cultured fibroblasts. J Biol Chem. 1981;256:8348-8356.
5. Oram JF. The effects of high density lipoprotein subfractions on cholesterol homeostasis in human fibroblasts and arterial smooth muscle cells. Arteriosclerosis. 1983;3:420-432.
6. 2 (prostacyclin) by cultured human and bovine endothelial cells. Proc Natl Acad Sci USA. 1977;74:3922-3926.
7. Baezinger NL, Becherer PR, Majerus PW. Characterization of prostacyclin synthesis in cultured human arterial smooth muscle cells, venous endothelial cells and skin fibroblasts. Cell. 1979;16: 967-974.
8. Moncada S, Vane JR. Arachidonic acid metabolites and the interactions between platelets and blood-vessel walls. N Engl J Med. 1979;300:1142-1147.
9. 2) by layers of the arterial wall: an explanation for the anti-thrombotic properties of vascular endothelium. Thromb Res. 1977;11:323-344.
10. Thiemermann C. Biosynthesis and interaction of endothelium-derived vasoactive mediators. Eicosanoids. 1991;4:187-202.
11. Hla T, Neilson K. Human cyclooxygenase-2 cDNA. Proc Nat Acad Sci USA. 1992;89:7384-7388.
12. Xie W, Chipman JG, Robertson DL, Erikson RL, Simmons DL. Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing. Proc Natl Acad Sci USA. 1991;88:2692-2696.
13. DeWitt DL. Prostaglandin endoperoxide synthase: regulation of enzyme expression. Biochim Biophys Acta. 1991;1083:121-134.
14. Pilbeam CC, Kawaguchi H, Hakeda Y, Voznesensky O, Alander CB, Raisz LG. Differential regulation of inducible and constitutive prostaglandin endoperoxide synthase in osteoblastic MC3T3-E1 cells. J Biol Chem. 1993;268:25643-25649.
15. Reddy ST, Hershman HR. Ligand-induced prostaglandin synthesis requires expression of the TIS10/PGS-2 prostaglandin synthase gene in murine fibroblasts and macrophages. J Biol Chem. 1994; 263:15473-15480.
16. Badimon JJ, Badimon L, Galvez A, Dische R, Fuster V. High density lipoprotein plasma fraction inhibits aortic fatty streaks in cholesterol-fed rabbits. J Lab Invest. 1989;60:455-461.
17. Badimon JJ, Badimon L, Fuster V. Regression of atherosclerosis lesions by high density plasma fraction in the cholesterol-fed rabbit. J Clin Invest. 1990;85:1234-1241.
18. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the folin phenol reagent. J Biol Chem. 1951;193: 265-275.
19. Martínez-González J, Badimon L. Human and porcine smooth muscle cells share similar proliferation dependence on the mevalonate pathway: implication for in vivo interventions in the porcine model. Eur J Clin Invest. 1996;26:1023-1032.
20. Masferrer JL, Zweifel BS, Manning PT, Hauser SD, Leahy KM, Smith WS, Isakson PC, Seibert K. Selective inhibition of inducible cyclooxygenase-2 in vivo is antiinflammatory and nonulcerogenic. Proc Natl Acad Sci USA. 1994;91:3228-3232.
21. Futaki N, Takahashi S, Yokoyama M, Higuchi S, Otomo S. NS-398, a new anti-inflammatory agent, selectively inhibits prostaglandin G/H synthase/cyclooxygenase (Cox-2) activity in vitro. Prostaglandins. 1994;47:55-59.
22. Zhang F, Warskulat U, Wettstein M, Screiber R, Henninger H, Decker K, Haussinger P. Hyperosmolarity stimulates prostaglandin synthesis and cyclooxygenase-2 expression in activated rat liver macrophages. Biochem J. 1995;312:135-143.