Critical reduction β-cell mass results in two distinct outcomes over time. Adaptation with impaired glucose tolerance or decompensated diabetes

Journal of Biological Chemistry

Volumn 278, Issue 5, 2003, Pages 2997-3005

  Laybutt, D Ross ^a   Glandt, Mariela ^c   Xu, Gang ^c   Ahn, Yu Bai ^c   Trivedi, Nitin ^c   Bonner Weir, Susan ^c   Weir, Gordon C ^b  

^a GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b JOSLIN DIABETES CENTER   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

DISEASES; GENES; GLUCOSE; INSULIN;

GENE EXPRESSION;

BIOCHEMISTRY;

ADENOSINE TRIPHOSPHATASE (CALCIUM); AMYLIN; FAS ANTIGEN; GLUCOKINASE; GLUCOSE; GLUCOSE 6 PHOSPHATASE; GLUCOSE TRANSPORTER 2; GLYCEROL 3 PHOSPHATE DEHYDROGENASE; HEME OXYGENASE 1; HEXOKINASE; HEXOKINASE ISOENZYME; HOMEODOMAIN PROTEIN; INSULIN; LACTATE DEHYDROGENASE; LACTATE DEHYDROGENASE ISOENZYME 5; MESSENGER RNA; MYC PROTEIN; NEUROGENIC DIFFERENTIATION FACTOR; NUCLEAR FACTOR I; NUCLEAR FACTOR IALPHA; PYRUVATE CARBOXYLASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NKX6.1; UNCLASSIFIED DRUG; PROTEIN;

ADAPTATION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL COUNT; CELL DIFFERENTIATION; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE SEVERITY; GENE EXPRESSION; GENE REPRESSION; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; HYPERTROPHY; IMPAIRED GLUCOSE TOLERANCE; INSULIN RELEASE; MALE; NONHUMAN; PANCREAS ISLET BETA CELL; PANCREAS RESECTION; PHENOTYPE; PRIORITY JOURNAL; RAT; ANIMAL; GENE EXPRESSION REGULATION; GENETICS; GLUCOSE INTOLERANCE; HISTOLOGY; METABOLISM; ORGAN SIZE; PANCREAS ISLET; PATHOPHYSIOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT; TIME;

ANIMALIA;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS; GENE EXPRESSION REGULATION; GLUCOSE INTOLERANCE; HYPERGLYCEMIA; ISLETS OF LANGERHANS; MALE; ORGAN SIZE; PANCREATECTOMY; PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; TIME FACTORS;

EID: 0037474332     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M210581200     Document Type: Article

References (51)

1. Deeney, J. T., Prentki, M., and Corkey, B. E. (2000) Semin. Cell Dev. Biol. 11, 267-275
2. Newgard, C. B., and Matschinsky, F. M. (2000) in Handbook of Physiology, Section 7: The Endocrine System, Vol. II (Jefferson, L. S., and Cherrington, A. D., eds) pp. 125-151, American Physiological Society, Oxford University Press, New York
3. Bruning, J. C., Winnay, J., Bonner-Weir, S., Taylor, S. I., Accili, D., and Kahn, C. R. (1997) Cell 88, 561-572
4. Pick, A., Clark, J., Kubstrup, C., Levisetti, M., Pugh, W., Bonner-Weir, S., and Polonsky, K. S. (1998) Diabetes 47, 358-364
5. Weir, G. C., Laybutt, D. R., Kaneto, H., Bonner-Weir, S., and Sharma, A. (2001) Diabetes 50, Suppl. 1, 154-159
6. Waeber, G., Thompson, N., Nicod, P., and Bonny, C. (1996) Mol. Endocrinol. 10, 1327-1334
7. Ahlgren, U., Jonsson, J., Jonsson, L., Simu, K., and Edlund, H. (1998) Genes Dev. 12, 1763-1768
8. Naya, F. J., Huang, H. P., Qiu, Y., Mutoh, H., DeMayo, F. J., Leiter, A. B., and Tsai, M. J. (1997) Genes Dev. 11, 2323-2334
9. Sander, M., and German, M. S. (1997) J. Mol. Med. 75, 327-340
10. Sander, M., Sussel, L., Conners, J., Scheel, D., Kalamaras, J., Dela Cruz, F., Schwitzgebel, V., Hayes-Jordan, A., and German, M. (2000) Development 127, 5533-5540
11. Huang, H. P., and Tsai, M. J. (2000) J. Biomed. Sci. 7, 27-34
12. Schwitzgebel, V. M., Scheel, D. W., Conners, J. R., Kalamaras, J., Lee, J. E., Anderson, D. J., Sussel, L., Johnson, J. D., and German, M. S. (2000) Development 127, 3533-3542
13. Jonas, J. C., Sharma, A., Hasenkamp, W., Ilkova, H., Patane, G., Laybutt, R., Bonner-Weir, S., and Weir, G. C. (1999) J. Biol. Chem. 274, 14112-14121
14. Laybutt, D. R., Kaneto, H., Hasenkamp, W., Grey, S., Jonas, J. C., Sgroi, D. C., Groff, A., Ferran, C., Bonner-Weir, S., Sharma, A., and Weir, G. C. (2002) Diabetes 51, 413-423
15. Laybutt, D. R., Sharma, A., Sgroi, D. C., Gaudet, J., Bonner-Weir, S., and Weir, G. C. (2002) J. Biol. Chem. 277, 10912-10921
16. Bonner-Weir, S., Trent, D. F., and Weir, G. C. (1983) J. Clin. Invest. 71, 1544-1553
17. Xu, G., Stoffers, D. A., Habener, J. F., and Bonner-Weir, S. (1999) Diabetes 48, 2270-2276
18. Bonner-Weir, S., Baxter, L. A., Schuppin, G. T., and Smith, F. E. (1993) Diabetes 42, 1715-1720
19. Zambon, A., Hashimoto, S. I., and Brunzell, J. D. (1993) J. Lipid Res. 34, 1021-1028
20. Steil, G. M., Trivedi, N., Jonas, J. C., Hasenkamp, W. M., Sharma, A., Bonner-Weir, S., and Weir, G. C. (2001) Am. J. Physiol. 280, E788-E796
21. Jonas, J. C., Laybutt, D. R., Steil, G. M., Trivedi, N., Pertusa, J. G., Van de Casteele, M., Weir, G. C., and Henquin, J. C. (2001) J. Biol. Chem. 276, 35375-35381
22. Katic, M., Hadzija, M., Wrischer, M., and Pavelic, K. (1999) Carcinogenesis 20, 1521-1527
23. Welsh, N., Margulis, B., Borg, L. A., Wiklund, H. J., Saldeen, J., Flodstrom, M., Mello, M. A., Andersson, A., Pipeleers, D. G., and Hellerstrom, C. (1995) Mol. Med. 1, 806-820
24. Tiedge, M., Lortz, S., Drinkgern, J., and Lenzen, S. (1997) Diabetes 46, 1733-1742
25. Suzuki, K., Bonner-Weir, S., Trivedi, N., Yoon, K. H., Hollister-Lock, J., Colton, C. K., and Weir, G. C. (1998) Transplantation 66, 21-28
26. Tokuyama, Y., Sturis, J., DePaoli, A. M., Takeda, J., Stoffel, M., Tang, J., Sun, X., Polonsky, K. S., and Bell, G. I. (1995) Diabetes 44, 1447-1457
27. Brunzell, J. D., Robertson, R. P., Lerner, R. L., Hazzard, W. R., Ensinck, J. W., Bierman, E. L., and Porte, D., Jr. (1976) J. Clin. Endocrinol. Metab. 42, 222-229
28. Srikanta, S., Ganda, O. P., Gleason, R. E., Jackson, R. A., Soeldner, J. S., and Eisenbarth, G. S. (1984) Diabetes 33, 717-720
29. Leahy, J. L., Bonner-Weir, S., and Weir, G. C. (1992) Diabetes Care 15, 442-455
30. Portha, B., Giroix, M. H., Serradas, P., Morin, L., Saulnier, C., and Bailbe, D. (1994) Diabetes Metab. 20, 108-115
31. Ogawa, Y., Noma, Y., Davalli, A. M., Wu, Y. J., Thorens, B., Bonner-Weir, S., and Weir, G. C. (1995) Diabetes 44, 75-79
32. Leibowitz, G., Ferber, S., Apelqvist, A., Edlund, H., Gross, D. J., Cerasi, E., Melloul, D., and Kaiser, N. (2001) Diabetes 50, 1799-1806
33. Brissova, M., Shiota, M., Nicholson, W. E., Gannon, M., Knobel, S. M., Piston, D. W., Wright, C. V., and Powers, A. C. (2002) J. Biol. Chem. 277, 11225-11232
34. Ferber, S., Halkin, A., Cohen, H., Ber, I., Einav, Y., Goldberg, I., Barshack, I., Seijffers, R., Kopolovic, J., Kaiser, N., and Karasik, A. (2000) Nat. Med. 6, 568-572
35. Ainscow, E. K., Zhao, C., and Rutter, G. A. (2000) Diabetes 49, 1149-1155
36. Alcazar, O., Tiedge, M., and Lenzen, S. (2000) Biochem. J. 352, 373-380
37. Sekine, N., Cirulli, V., Regazzi, R., Brown, L. J., Gine, E., Tamarit-Rodriguez, J., Girotti, M., Marie, S., MacDonald, M. J., and Wollheim, C. B. (1994) J. Biol. Chem. 269, 4895-4902
38. Schuit, F., De Vos, A., Farfari, S., Moens, K., Pipeleers, D., Brun, T., and Prentki, M. (1997) J. Biol. Chem. 272, 18572-18579
39. Scaglia, L., Smith, F. E., and Bonner-Weir, S. (1995) Endocrinology 136, 5461-5468
40. Schuhmacher, M., Staege, M. S., Pajic, A., Polack, A., Weidle, U. H., Bornkamm, G. W., Eick, D., and Kohlhuber, F. (1999) Curr. Biol. 9, 1255-1258
41. Laybutt, D. R., Weir, G. C., Kaneto, H., Lebet, J., Palmiter, R. D., Sharma, A., and Bonner-Weir, S. (2002) Diabetes 51, 1793-1804
42. Pelengaris, S., Khan, M., and Evan, G. I. (2002) Cell 109, 321-334
43. Kosaka, K., Kuzuya, T., Akanuma, Y., and Hagura, R. (1980) Diabetologia 18, 23-28
44. Garvey, W. T., Olefsky, J. M., Griffin, J., Hamman, R. F., and Kolterman, O. G. (1985) Diabetes 34, 222-234
45. Gremlich, S., Bonny, C., Waeber, G., and Thorens, B. (1997) J. Biol. Chem. 272, 30261-30269
46. Bollheimer, L. C., Skelly, R. H., Chester, M. W., McGarry, J. D., and Rhodes, C. J. (1998) J. Clin. Invest. 101, 1094-1101
47. Shimabukuro, M., Zhou, Y. T., Levi, M., and Unger, R. H. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 2498-2502
48. Yoshikawa, H., Tajiri, Y., Sako, Y., Hashimoto, T., Umeda, F., and Nawata, H. (2001) Metabolism 50, 613-618
49. Lee, Y., Hirose, H., Ohneda, M., Johnson, J. H., McGarry, J. D., and Unger, R. H. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 10878-10882
50. Harmon, J. S., Gleason, C. E., Tanaka, Y., Poitout, V., and Robertson, R. P. (2001) Diabetes 50, 2481-2486
51. Jensen, J., Serup, P., Karlsen, C., Nielsen, T. F., and Madsen, O. D. (1996) J. Biol. Chem. 271, 18749-18758