Lentiviral gene transfer into primary and secondary NOD/SCID repopulating cells

Blood

Volumn 96, Issue 12, 2000, Pages 3725-3733

  Woods, N B ^a   Fahlman, C ^a   Mikkola, H ^a   Hamaguchi, I ^a   Olsson, K ^a   Zufferey, R ^a   Jacobsen, S E ^a   Trono, D ^a   Karlsson, S ^a  

^a LUND UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; GREEN FLUORESCENT PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; PHOSPHOGLYCERATE KINASE; VIRUS VECTOR;

ANIMAL CELL; ARTICLE; COLONY FORMING UNIT GM; CONTROLLED STUDY; FLOW CYTOMETRY; GENE TRANSFER; GENETIC TRANSDUCTION; HELA CELL; HEMATOPOIETIC STEM CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; LENTIVIRINAE; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGENY; PROMOTER REGION; SCID MOUSE; SOUTHERN BLOTTING; TRANSGENE; UMBILICAL CORD BLOOD; VESICULAR STOMATITIS VIRUS;

EID: 0034548823     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v96.12.3725.h8003725_3725_3733     Document Type: Article

References (37)

1. Retroviral gene transfer to primitive normal and leukemic hematopoietic cells using clinically applicable procedures
2. Retroviral-mediated gene transfer into CD34-enriched human peripheral blood stem cells
3. The basic science of gene therapy
4. Gene therapy for hematopoietic and lymphoid disorders
5. Gene transfer to hematopoietic cells - The clinical experience
6. Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection
7. Passage through mitosis is required for oncoretroviruses but not for the human immunodeficiency virus
8. In vivo delivery and stable transduction of nondividing cells by a lentiviral vector
9. Stable and efficient gene transfer into the retina using an HIV-based lentiviral vector
10. + cells with a human immunodeficiency virus type 1-based retroviral vector pseudotyped with vesicular stomatitis virus envelope glycoprotein G
11. Stable integration of human immunodeficiency virus-based retroviral vectors into the chromosomes of nondividing cells
12. Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo
13. Characterization of membrane components of the erythrocyte involved in vesicular stomatitis virus attachment and fusion at acidic pH
14. Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: Concentration to very high liter and efficient gene transfer into mammalian and nonmammalian cells
15. Transduction of nondividing cells using pseudotyped defective high-titer HIV type 1 particles
16. Transduction of human progenitor hematopoietic stem cells by human immunodeficiency virus type 1-based vectors is cell cycle dependent
17. HIV, but not murine leukemia virus, vectors mediate high efficiency gene transfer into freshly isolated G0/G1 human hematopoietic stem cells
18. + cells that mediate long-term engraftment of NOD/SCID mice by HIV vectors
19. - human hematopoietic cells by HIV-1-based lentiviral vectors
20. + cells via human immunodeficiency virus-based gene transfer vectors
21. Primary structure of Aequorea victoria green fluorescent protein
22. Green fluorescent protein as a marker for gene expression
23. Use of green fluorescent protein variants to monitor gene transfer and expression in mammalian cells
24. Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow: Implications for gene therapy
25. Primitive human hematopoietic cells are enriched in cord blood compared with adult bone marrow or mobilized peripheral blood as measured by the quantitative in vivo SCID-repopulating cell assay
26. Human growth factor-enhanced regeneration of transplantable human hematopoietic stem cells in nonobese diabetic/severe combined immunodeficient mice
27. A third-generation lentivirus vector with a conditional packaging system
28. A GFP reporter system to assess gene transfer and expression in human hematopoietic progenitor cells
29. A stable cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes
30. Expression of introduced sequences in hematopoietic cells following retroviral-mediated gene transfer
31. High-resolution cell cycle analysis of defined phenotypic subsets within primitive human hematopoietic cell populations
32. Modulation of gene expression in multiple hematopoietic cell lineages following retroviral gene transfer
33. Lentiviral gene expression during ES cell derived hematopoietic development in vitro
34. Gene transfer into human hematopoietic progenitor cells: A review of current clinical protocols
35. Consistent, persistent expression from modified retroviral vectors in murine hematopoietic stem cells
36. Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors
37. Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery