Reversible immortalization of human primary cells by lentivector-mediated transfer of specific genes

Molecular Therapy

Volumn 2, Issue 4, 2000, Pages 404-414

  Salmon, Patrick ^a   Oberholzer, José ^a   Occhiodoro, Teresa ^a   Morel, Philippe ^a   Lou, Jinning ^a   Trono, Didier ^a  

^a UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

Author keywords

Bmi 1; Conditional immortalization; Gene therapy; Gene transfer; HIV vectors; Insulin; Lentiviral vectors; LoxP Cre; Pancreatic beta cell; Reversible immortalization; SV40 large T; Telomerase

Indexed keywords

INTEGRASE; NUCLEAR PROTEIN; PRIMER DNA; TELOMERASE; VIRUS T ANTIGEN;

ANIMAL; ARTICLE; BIOPSY; BIOSYNTHESIS; CELL DIFFERENTIATION; CELL DIVISION; CELL TRANSPLANTATION; CHEMISTRY; CYTOLOGY; FLOW CYTOMETRY; GENE THERAPY; GENE TRANSFER; GENE VECTOR; GENETIC RECOMBINATION; GENETICS; HELA CELL; HUMAN; IMMUNOHISTOCHEMISTRY; LENTIVIRINAE; LIVER; METABOLISM; METHODOLOGY; MOUSE; NUDE MOUSE; PANCREAS ISLET; POLYMERASE CHAIN REACTION; VASCULAR ENDOTHELIUM; VIROLOGY; VIRUS CELL TRANSFORMATION; WESTERN BLOTTING;

ANIMALS; ANTIGENS, POLYOMAVIRUS TRANSFORMING; BIOPSY; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELL DIVISION; CELL TRANSFORMATION, VIRAL; CELL TRANSPLANTATION; DNA PRIMERS; ENDOTHELIUM, VASCULAR; FLOW CYTOMETRY; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HELA CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; INTEGRASES; ISLETS OF LANGERHANS; LENTIVIRUS; LIVER; MICE; MICE, NUDE; NUCLEAR PROTEINS; POLYMERASE CHAIN REACTION; RECOMBINATION, GENETIC; TELOMERASE;

EID: 0034296940     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1006/mthe.2000.0141     Document Type: Article

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