Radiation-induced damage in two human glioma cell lines as measured by the nucleoid assay

Anticancer Research

Volumn 17, Issue 6 D, 1997, Pages 4615-4618

  Wang, Jingli ^a   Lily, Hu ^a   Allalunis Turner, M Joan ^c   Day III, Rufus S ^c   Deen, Dennis F ^a,b,d  

^a Brain Tumor Research Center   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF ALBERTA   (Canada)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

DNA supercoiling; Human glioma cells; Ionizing radiation; Nucleoid halo; Radiosensitivity

Indexed keywords

ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DNA SUPERCOILING; GLIOMA CELL; HUMAN; HUMAN CELL; LYSIS; PRIORITY JOURNAL; RADIATION INJURY;

CELL NUCLEUS; DNA DAMAGE; DNA REPAIR; DNA, NEOPLASM; DNA, SUPERHELICAL; DOSE-RESPONSE RELATIONSHIP, RADIATION; GLIOMA; HUMANS; KINETICS; TUMOR CELLS, CULTURED; X-RAYS;

EID: 2642604235     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Hoffman W, Levin V and Wilson C: Evaluation of malignant glioma patients during the postirradiation period. J Neurosurg 50: 625-628, 1979.
2. Malyapa R, Wright W and Roti Roti J: DNA supercoiling changes and nucleoid protein composition in a group of L5178Y cells of varying radiosensitivity. Rad Res 145: 239-242, 1996.
3. Milner A, Gordon D, Turner B and Vaughan A: A correlation between DNA-nuclear matrix binding and relative radiosensitivity in two human squamous cell carcinoma cell lines. Int J Rad Biol 63: 13-20, 1993.
4. Vaughan A, Anderson P, Wallace D, Beaney R and Lynch T: Local control of T2/3 transitional cell carcinoma of bladder is correlated to differences in DNA supercoiling: evidence for two discrete tumor populations. Cancer Res 53: 2300-2303, 1993.
5. Roti-Roti J and Wright W: Visualization of DNA loops in Nucleoids from Hela cells: assays for DNA damage and repair. Cytometry 8: 461-467, 1987.
6. Milner A, Vaughan A and Clarke I: Measurement of DNA damage in mammalian cells using flow cytometry. Rad Res 110: 108-117, 1987.
7. Wang J, Hyun W, Lamborn K and Deen D: Measurement of radiation-induced damage in human glioma cells with flow cytometry. Cancer Res 56: 154-157, 1996.
8. Vogelstein B, Pardoll D and Coffey D: Supercoiled loops and eucaryotic DNA replication. Cell 22: 79-85, 1980.
9. Allalunis-Turner J, Barron G, Day III R, Dobler K and Mirzayans R: Isolation of two cell lines from a human malignant glioma specimen differing in sensitivity to radiation and chemotherapeutic drugs. Rad Res 134: 349-54, 1993.
10. Lees-Miller S, Godbout R, Chan D, Weinfeld M, Day Rr, Barron G and Allalunis-Turner J: Absence of p350 subunit of DNA-activated protein kinase from a radiosensitive human cell line. Science 267: 1183-5, 1995.
11. Malyapa R, Wright W and Roti Roti J: Radiation sensitivity correlates with changes in DNA supercoiling and nucleoid protein content in cells of three chinese hamster cell lines. Rad Res 140: 312-320, 1994.
12. Schwartz J, Cowen J, Moan E, Sedita B, Stephens J and Vaughan A: Metaphase chromosome and nucleoid differences between CHO-K1 and its radiosensitive derivative xrs-5. Mutagenesis 8: 105-108, 1993.
13. Weaver D: What to do at an end: DNA double-strand break repair. Trends in Genetics 11: 388-392, 1995.
14. Suwa A, Hirakata M, Takeda Y, Jesch S, Mimori T and Hardin J: DNA-dependent protein kinase (Ku protein-p350 complex) assembles on double stranded DNA. Proc Natl Acad Sci 91: 6904-6908, 1994.
15. Jeggo P and Thompson L: Nomenclature of human genes involved in ionizing radiation sensitivity. Mutation Res 337: 131-134, 1995.
16. Wilks D, Barry J, Hughes M and West C: Assessment of light scatter by nucleoids as a rapid predictive assay of radiosensitivity. Rad Res 146: 628-635, 1996.
17. Wang J, Basu H, Hu L, Feuerstein B, Petra M and Deen D: Radiation-induced changes in nucleoid halo diameters of aerobic and hypoxic SF-126 human brain tumor cells. Cytometry 19: 107-111, 1995.