Up-regulation of cDK5/p35 by oxidative stress in human neuroblastoma IMR-32 cells

Journal of Cellular Biochemistry

Volumn 88, Issue 4, 2003, Pages 758-765

  Strocchi, Paola ^a   Pession, Annalisa ^a   Dozza, Barbara ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Cdk5; Kinase activity; Neuroblastoma cells; Oxidative stress; p35

Indexed keywords

4 HYDROXYNONENAL; ASCORBIC ACID; CYCLIN DEPENDENT KINASE; FERROUS SULFATE; PROTEIN P35; PROTEIN P39; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CATALYSIS; CELL FUNCTION; CONTROLLED STUDY; DEGENERATIVE DISEASE; DEREGULATION; DISEASE ASSOCIATION; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; NERVE CELL; NEUROBLASTOMA CELL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FAMILY; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; UPREGULATION;

ALDEHYDES; ALZHEIMER DISEASE; AMYOTROPHIC LATERAL SCLEROSIS; CELL SURVIVAL; CYCLIN-DEPENDENT KINASE 5; CYCLIN-DEPENDENT KINASES; ENZYME ACTIVATION; FERROUS COMPOUNDS; HUMANS; MICROSCOPY, PHASE-CONTRAST; NERVE TISSUE PROTEINS; NEUROBLASTOMA; OXIDATIVE STRESS; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED; UP-REGULATION;

EID: 0037373079     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcb.10391     Document Type: Article

References (49)

1. Adams JD, J., Chang ML, Klaidman L. 2001. Parkinson's disease-redox mechanisms. Curr Med Chem 8:809-814 (review).
2. Allen RG, Tresini M. 2000. Oxidative stress and gene regulation. Free Radic Biol Med 28:463-499 (review).
3. Bajaj NP. 2000. Cyclin-dependent kinase-5 (CDK5) and amyotrophic lateral sclerosis. Amyotroph Lateral Scler Other Motor Neuron Disord 1:319-327 (review).
4. Beckmann AM, Wilce PA. 1997. Egr transcription factors in the nervous system. Neurochem Int 31:477-510 (review).
5. Borghi R, Giliberto L, Assini A, Delacourte A, Perry G, Smith MA, Strocchi P, Zaccheo D, Tabaton M. 2002. Increase of cdk5 is related to neurofibrillary pathology in progressive supranuclear palsy. Neurology 58:589-592.
6. Chatterjee S, Zaman K, Ryu H, Conforto A, Ratan RR. 2001. Sequence-selective DNA binding drugs mithramycin A and chromomycin A3 are potent inhibitors of neuronal apoptosis induced by oxidative stress and DNA damage in cortical neurons. Ann Neurol 49:345-354.
7. Delalle I, Bhide PG, Caviness VS, Jr., Tsai LH. 1997. Temporal and spatial patterns of expression of p35, a regulatory subunit of cyclin-dependent kinase 5, in the nervous system of the mouse. J Neurocytol 26:283-296.
8. Dhavan R, Tsai LH. 2001. A decade of cdk5. Nat Rev Mol Cell Biol 2:749-759.
9. Grant P, Sharma P, Pant HC. 2001. Cyclin-dependent protein kinase 5 (cdk5) and the regulation of neurofilament metabolism. Eur J Biochem 268:1534-1546 (review).
10. Green LM, Reade JL, Ware CF. 1984. Rapid colorimetric assay for cell viability: Application to the quantitation of cytotoxic and growth inhibitory lymphokines. J Immunol Methods 70:257-268.
11. Harada T, Morooka T, Ogawa S, Nishida E. 2001. ERK induces p35, a neuron-specific activator of cdk5, through induction of Egr1. Nat Cell Biol 3:453-459.
12. Humbert S, Dhavan R, Tsai L. 2000. p39 activates cdk5 in neurons, and is associated with the actin cytoskeleton. J Cell Sci 113:975-983.
13. Kruman I, Bruce-Keller AJ, Bredesen D, Waeg G, Mattson MP. 1997. Evidence that 4-hydroxynonenal mediates oxidative stress-induced neuronal apoptosis. J Neurosci 17:5089-5100.
14. Kusakawa G, Saito T, Onuki R, Ishiguro K, Kishimoto T, Hisanaga S. 2000. Calpain-dependent proteolytic cleavage of the p35 cyclin-dependent kinase 5 activator to p25. J Biol Chem 275:17166-17172.
15. Laemmli UK. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685.
16. Lee MS, Kwon YT, Li M, Peng J, Friedlander RM, Tsai LH. 2000. Neurotoxicity induces cleavage of p35 to p25 by calpain. Nature 405:360-364.
17. Lew J, Wang JH. 1995. Neuronal cdc2-like kinase. Trends Biochem Sci 20:33-37 (review).
18. Lew J, Huang QQ, Qi Z, Winkfein RJ, Aebersold R, Hunt T, Wang JH. 1994. A brain-specific activator of cyclin-dependent kinase 5. Nature 371:423-426.
19. Maccioni RB, Otth C, Concha II, Munoz JP. 2001. The protein kinase cdk5. Structural aspects, roles in neurogenesis and involvement in Alzheimer's pathology. Eur J Biochem 268:1518-1527 (review).
20. Mosmann T. 1983. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J Immunol Methods 65:55-63.
21. Nath R, Davis M, Probert AW, Kupina NC, Ren X, Schielke GP, Wang KK. 2000. Processing of cdk5 activator p35 to its truncated form (p25) by calpain in acutely injured neuronal cells. Biochem Biophys Res Commun 274:16-21.
22. Nikolic M, Tsai LH. 2000. Activity and regulation of p35/cdk5 kinase complex. Methods Enzymol 325:200-213.
23. Nikolic M, Dudek H, Kwon YT, Ramos YF, Tsai LH. 1996. The cdk5/p35 kinase is essential for neurite outgrowth during neuronal differentiation. Genes Dev 10:816-825.
24. Nose K, Ohba M. 1996. Functional activation of the egr-1 (early growth response-1) gene by hydrogen peroxide. Biochem J 316:381-383.
25. Nose K, Shibanuma M, Kikuchi K, Kageyama H, Sakiyama S, Kuroki T. 1991. Transcriptional activation of early-response genes by hydrogen peroxide in a mouse osteoblastic cell line. Eur J Biochem 201(1):99-106.
26. O'Donovan KJ, Tourtellotte WG, Millbrandt J, Baraban JM. 1999. The EGR family of transcription-regulatory factors: Progress at the interface of molecular and systems neuroscience. Trends Neurosci 22:167-173 (review).
27. Ohba M, Shibanuma M, Kuroki T, Nose K. 1994. Production of hydrogen peroxide by transforming growth factor-beta 1 and its involvement in induction of egr-1 in mouse osteoblastic cells. J Cell Biol 126:1079-1088.
28. Ohshima T, Nagle JW, Pant HC, Joshi JB, Kozak CA, Brady RO, Kulkarni AB. 1995. Molecular cloning and chromosomal mapping of the mouse cyclin-dependent kinase 5 gene. Genomics 28:585-588.
29. Ohshima T, Ward JM, Huh CG, Longenecker G, Veeranna, Pant HC, Brady RO, Martin LJ, Kulkarni AB. 1996. Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death. Proc Natl Acad Sci USA 93:11173-11178.
30. Paglini G, Caceres A. 2001. The role of the cdk5-p35 kinase in neuronal development. Eur J Biochem 268:1528-1533.
31. Patrick GN, Zukerberg L, Nikolic M, de la Monte S, Dikkes P, Tsai LH. 1999. Conversion of p35 to p25 deregulates cdk5 activity and promotes neurodegeneration. Nature 402:615-622.
32. Patzke H, Tsai LH. 2002. cdk5 sinks into ALS. Trends Neurosci 25:8-10 (review).
33. Pei JJ, Grundke-Iqbal I, Iqbal K, Bogdanovic N, Winblad B, Cowburn RF. 1998. Accumulation of cyclin-dependent kinase 5 (cdk5) in neurons with early stages of Alzheimer's disease neurofibrillary degeneration. Brain Res 797:267-277.
34. Ross S, Tienhaara A, Lee MS, Tsai LH, Gill G. 2002. GC box-binding transcription factors control the neuronal specific transcription of the cyclin-dependent kinase 5 regulator p35. J Biol Chem 277:4455-4464.
35. Sayre LM, Smith MA, Perry G. 2001. Chemistry and biochemistry of oxidative stress in neurodegenerative disease. Curr Med Chem 8:721-738 (review).
36. Sherer TB, Betarbet R, Greenamyre JT. 2001. Pathogenesis of Parkinson's disease. Curr Opin Investig Drugs 2:657-662 (review).
37. Smith DS, Greer PL, Tsai LH. 2001. cdk5 on the brain. Cell Growth Differ 12:277-283 (review).
38. Takahashi M, Iseki E, Kosaka K. 2000. cdk5 and munc-18/ p67 co-localization in early stage neurofibrillary tangles-bearing neurons in Alzheimer type dementia brains. J Neurol Sci 172:63-69.
39. Tamagno E, Aragno M, Parola M, Parola S, Brignardello E, Boccuzzi G, Danni O. 2000. NT2 neurons, a classical model for Alzheimer's disease, are highly susceptible to oxidative stress. Neuroreport 11:1865-1869.
40. Tang D, Yeung J, Lee KY, Matsushita M, Matsui H, Tomizawa K, Hatase O, Wang JH. 1995. An isoform of the neuronal cyclin-dependent kinase 5 (cdk5) activator. J Biol Chem 270:26897-26903.
41. Tomizawa K, Matsui H, Matsushita M, Lew J, Tokuda M, Itano T, Konishi R, Wang JH, Hatase O. 1996. Localization and developmental changes in the neuron-specific cyclin-dependent kinase 5 activator (p35nck5a) in the rat brain. Neuroscience 74:519-529.
42. Tsai LH, Takahashi T, Caviness VS, Jr., Harlow E. 1993. Activity and expression pattern of cyclin-dependent kinase 5 in the embryonic mouse nervous system. Development 119:1029-1040.
43. Tsai LH, Delalle I, Caviness VS Jr., Chae T, Harlow E. 1994. p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5. Nature 371(6436):419-423.
44. Tumilowicz JJ, Nichols WW, Cholon JJ, Greene AE. 1970. Definition of a continuous human cell line derived from neuroblastoma. Cancer Res 30:2110-2118.
45. Uchida K, Shiraishi M, Naito Y, Torii Y, Nakamura Y, Osawa T. 1999. Activation of stress signaling pathways by the end product of lipid peroxidation. 4-hydroxy-2-nonenal is a potential inducer of intracellular peroxide production. J Biol Chem 274:2234-2242.
46. Wu DC, Yu YP, Lee NT, Yu AC, Wang JH, Han YF. 2000. The expression of cdk5, p35, p39, and cdk5 kinase activity in developing, adult, and aged rat brains. Neurochem Res 25:923-929.
47. Yamaguchi H, Ishiguro K, Uchida T, Takashima A, LemereCA, Imahori K. 1996. Preferential labeling of Alzheimer neurofibrillary tangles with antisera for tau protein kinase (TPK) I/glycogen synthase kinase-3 beta and cyclin-dependent kinase 5, a component of TPK II. Acta Neuropathol (Berl) 92:232-241.
48. Yan GZ, Ziff EB. 1995. NGF regulates the PC12 cell cycle machinery through specific inhibition of the Cdk kinases and induction of cyclin Dl. J Neurosci 15:6200-6212.
49. Zhang Y, Tatsuno T, Carney JM, Mattson MP. 1993. Basic FGF, NGF, and IGFs protect hippocampal and cortical neurons against iron-induced degeneration. J Cereb Blood Flow Metab 13:378-388.