The expression of Cdk5, p35, p39, and Cdk5 kinase activity in developing, adult, and aged rat brains

Neurochemical Research

Volumn 25, Issue 7, 2000, Pages 923-929

  Wu, D C ^a   Yu, Y P ^a   Lee, N T K ^a   Yu, A C H ^a   Wang, J H C ^a   Han, Y F ^a  

^a HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

Author keywords

Cdk5; Cerebral cortex; Development; Hippocampus; p35; p39

Indexed keywords

CYCLIN DEPENDENT KINASE;

AGE; ARTICLE; BRAIN CORTEX; BRAIN LEVEL; CEREBELLUM; CONTROLLED STUDY; CORPUS STRIATUM; DEVELOPMENT; ENZYME ACTIVITY; ENZYME SPECIFICITY; FEMALE; HIPPOCAMPUS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

AGING; ANIMALS; BASE SEQUENCE; BRAIN; CYCLIN-DEPENDENT KINASES; DNA PRIMERS; FEMALE; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER;

EID: 0033870174     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1007544106645     Document Type: Article

References (24)

1. The cyclin-dependent protein kinases and the control of cell division
2. Neuronal cdc2-like kinase
3. Activity and expression pattern of cyclin-dependent kinase 5 in the embryonic mouse nervous system
4. Purification and characterization of a novel proline-directed protein kinase from bovine brain
5. Structure, function, and regulation of neuronal Cdc2-like protein kinase
6. Tau protein kinase I convert normal tau protein into A68-like component of paired helical filaments
7. Identification of the 23 kDa subunit of tau protein kinase II as a putative activator of Cdk5 in bovine brain
8. p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5
9. An isoform of the neuronal cyclin-dependent kinase 5 (Cdk5) activator
10. Phosphorylation of human high molecular weight neurofilament protein (hNF-H) by neuronal cyclin-dependent kinase 5 (cdk5)
11. Modulation of GSK-3-catalyzed phosphorylation of microtubule-associated protein tau by non-proline-dependent protein kinases
12. Neuronal cyclin-dependent kinase-5 phosphorylation sites in neurofilament protein (NF-H) are dephosphorylated by protein phosphatase 2A
13. Phosphorylation of the high molecular weight neurofilament protein (NF-H) by Cdk5 and p35
14. The Cdk5/p35 kinase is essential for neurite out-growth during neuronal differentiation
15. Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death
16. Mice lacking p35, a neuronal specific activator of Cdk5, display cortical lamination defects, seizures, and adult lethality
17. Physiology and pathology of tau protein kinases in relation to Alzheimer's disease
18. Possible role of tau protein kinases in pathogenesis of Alzheimer's disease
19. Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration
20. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
21. Expression of Cdk5, p35, and Cdk5 kinase activity in the developing rat lens
22. Region-specific expression of cyclin-dependent kinase 5 (Cdk5) and its activators, p35 and p39, in the developing and adult rat central nervous system
23. Timetables of neurogenesis in the human brain based on experimentally dertermined patterns in the rat
24. Association of neurofilament proteins with neuronal Cdk5 activator