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Volumn 138, Issue 5, 2003, Pages 883-893

Pharmacological characterization of the homomeric and heteromeric UNC-49 GABA receptors in C. elegans

Author keywords

C. elegans; GABA A receptors; Nematodes; UNC 49

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA; 4 AMINOBUTYRIC ACID A RECEPTOR BETA; 4 AMINOBUTYRIC ACID A RECEPTOR GAMMA; 4 AMINOBUTYRIC ACID RECEPTOR; ALFAXALONE; BENZODIAZEPINE; BICUCULLINE; DIELDRIN; ELTANOLONE; NEUROSTEROID; PENICILLIN G; PENTOBARBITAL; PICROTOXIN; PROPOFOL; PROTEIN UNC 49; PROTEIN UNC 49B; PROTEIN UNC 49C; RECEPTOR SUBUNIT; UNCLASSIFIED DRUG;

EID: 0037352879     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705119     Document Type: Article
Times cited : (48)

References (50)
  • 1
    • 0023484447 scopus 로고
    • Kinetic properties of the pentobarbitone-gated chloride current in frog sensory neurones
    • AKAIKE, N., MARUYAMA, T. & TOKUTOMI, N. (1987). Kinetic properties of the pentobarbitone-gated chloride current in frog sensory neurones. J. Physiol., 394, 85-98.
    • (1987) J. Physiol. , vol.394 , pp. 85-98
    • Akaike, N.1    Maruyama, T.2    Tokutomi, N.3
  • 2
    • 0033169088 scopus 로고    scopus 로고
    • The Caenorhabditis elegans unc-49 locus encodes multiple subunits of a heteromultimeric GABA receptor
    • BAMBER, B.A., BEG, A.A., TWYMAN, R.E. & JORGENSEN, E.M. (1999). The Caenorhabditis elegans unc-49 Locus Encodes Multiple Subunits of a Heteromultimeric GABA Receptor. J. Neurosci., 19, 5348-5359.
    • (1999) J. Neurosci. , vol.19 , pp. 5348-5359
    • Bamber, B.A.1    Beg, A.A.2    Twyman, R.E.3    Jorgensen, E.M.4
  • 3
    • 0029998302 scopus 로고    scopus 로고
    • Interaction of positive allosteric modulators with human and Drosophila recombinant GABA receptors expressed in Xenopus laevis oocytes
    • BELELLI, D., CALLACHAN, H., HILL-VENNING, C., PETERS, J.A. & LAMBERT, J.J. (1996). Interaction of positive allosteric modulators with human and Drosophila recombinant GABA receptors expressed in Xenopus laevis oocytes. Br. J. Pharmacol., 118, 563-576.
    • (1996) Br. J. Pharmacol. , vol.118 , pp. 563-576
    • Belelli, D.1    Callachan, H.2    Hill-Venning, C.3    Peters, J.A.4    Lambert, J.J.5
  • 4
    • 0032969799 scopus 로고    scopus 로고
    • The interaction of general anaesthetics and neurosteroids with GABA(A) and glycine receptors
    • BELELLI, D., PISTIS, M., PETERS, J.A. & LAMBERT, J.J. (1999). The interaction of general anaesthetics and neurosteroids with GABA(A) and glycine receptors. Neurochem. Int., 34, 447-452.
    • (1999) Neurochem. Int. , vol.34 , pp. 447-452
    • Belelli, D.1    Pistis, M.2    Peters, J.A.3    Lambert, J.J.4
  • 5
    • 0026247234 scopus 로고
    • A receptor subtypes: From pharmacology to molecular biology
    • A receptor subtypes: from pharmacology to molecular biology. Faseb J., 5, 2916-2923.
    • (1991) Faseb J. , vol.5 , pp. 2916-2923
    • Burt, D.R.1    Kamatchi, G.L.2
  • 9
    • 0030902186 scopus 로고    scopus 로고
    • A receptors comprised of alpha 1 beta 3 and beta 3 subunits expressed in human embryonic kidney 293 cells
    • A receptors comprised of alpha 1 beta 3 and beta 3 subunits expressed in human embryonic kidney 293 cells. Br. J. Pharmacol., 120, 899-909.
    • (1997) Br. J. Pharmacol. , vol.120 , pp. 899-909
    • Davies, P.A.1    Kirkness, E.F.2    Hales, T.G.3
  • 10
    • 0031836732 scopus 로고    scopus 로고
    • The methylglutamate, SYM 2081, is a potent and highly selective agonist at kainate receptors
    • DONEVAN, S.D., BEG, A., GUNTHER, J.M. & TWYMAN, R.E. (1998). The methylglutamate, SYM 2081, is a potent and highly selective agonist at kainate receptors. J. Pharmacol. Exp. Ther., 285, 539-545.
    • (1998) J. Pharmacol. Exp. Ther. , vol.285 , pp. 539-545
    • Donevan, S.D.1    Beg, A.2    Gunther, J.M.3    Twyman, R.E.4
  • 12
    • 0032951958 scopus 로고    scopus 로고
    • Picrotoxin blockade of invertebrate glutamate-gated chloride channels: Subunit dependence and evidence for binding within the pore
    • ETTER, A., CULLY, D.F., LIU, K.K., REISS, B., VASSILATIS, D.K., SCHAEFFER, J.M. & ARENA, J.P. (1999). Picrotoxin blockade of invertebrate glutamate-gated chloride channels: subunit dependence and evidence for binding within the pore. J. Neurochem., 72, 318-326.
    • (1999) J. Neurochem. , vol.72 , pp. 318-326
    • Etter, A.1    Cully, D.F.2    Liu, K.K.3    Reiss, B.4    Vassilatis, D.K.5    Schaeffer, J.M.6    Arena, J.P.7
  • 13
    • 0027280680 scopus 로고
    • A point mutation in a Drosophila GABA receptor confers insecticide resistance
    • FFRENCH-CONSTANT, R.H., ROCHELEAU, T.A., STEICHEN, J.C. & CHALMERS, A.E. (1993). A point mutation in a Drosophila GABA receptor confers insecticide resistance. Nature, 363, 449-451.
    • (1993) Nature , vol.363 , pp. 449-451
    • Ffrench-Constant, R.H.1    Rocheleau, T.A.2    Steichen, J.C.3    Chalmers, A.E.4
  • 14
    • 0028971185 scopus 로고
    • A response inhibition by β-lactam antibiotics in the pyramidal neurones of the rat cerebral cortex
    • A response inhibition by β-lactam antibiotics in the pyramidal neurones of the rat cerebral cortex. Br. J. Pharmacol., 116, 3014-3020.
    • (1995) Br. J. Pharmacol. , vol.116 , pp. 3014-3020
    • Fujimoto, M.1    Munakata, M.2    Akaike, N.3
  • 16
    • 12044253190 scopus 로고
    • An empirical test of bootstrapping as a method for assessing confidence in phylogenetic analysis
    • HILLIS, D.M. & BULL, J.J. (1993). An empirical test of bootstrapping as a method for assessing confidence in phylogenetic analysis. Syst. Biol., 42, 182-192.
    • (1993) Syst. Biol. , vol.42 , pp. 182-192
    • Hillis, D.M.1    Bull, J.J.2
  • 18
    • 0029868453 scopus 로고    scopus 로고
    • Allosteric modulation of an expressed homo-oligomeric GABA-gated chloride channel of Drosophila melanogaster
    • HOSIE, A.M. & SATTELLE, D.B. (1996). Allosteric modulation of an expressed homo-oligomeric GABA-gated chloride channel of Drosophila melanogaster. Br. J. Pharmacol., 117, 1229-1237.
    • (1996) Br. J. Pharmacol. , vol.117 , pp. 1229-1237
    • Hosie, A.M.1    Sattelle, D.B.2
  • 19
    • 0020526909 scopus 로고
    • Difference in the picrotoxinin receptor between the cyclodiene-resistant and susceptible strains of the German cockroach
    • KADOUS, A.A., GHIASUDDIN, S.M., MATSUMURA, F., SCOTT, J.G. & TANAKA, K. (1983). Difference in the Picrotoxinin Receptor between the Cyclodiene-Resistant and Susceptible Strains of the German Cockroach. Pestic. Biochem. Physiol., 19, 157-166.
    • (1983) Pestic. Biochem. Physiol. , vol.19 , pp. 157-166
    • Kadous, A.A.1    Ghiasuddin, S.M.2    Matsumura, F.3    Scott, J.G.4    Tanaka, K.5
  • 21
    • 0029869912 scopus 로고    scopus 로고
    • Homomeric beta 1 gamma-aminobutyric acid A receptor-ion channels: Evaluation of pharmacological and physiological properties
    • KRISHEK, B.J., MOSS, S.J. & SMART, T.G. (1996b). Homomeric beta 1 gamma-aminobutyric acid A receptor-ion channels: evaluation of pharmacological and physiological properties. Mol. Pharmacol., 49, 494-504.
    • (1996) Mol. Pharmacol. , vol.49 , pp. 494-504
    • Krishek, B.J.1    Moss, S.J.2    Smart, T.G.3
  • 22
    • 0032536499 scopus 로고    scopus 로고
    • A receptors expressed in xenopus oocytes: Influence of alpha- and gamma2- subunits
    • A receptors expressed in xenopus oocytes: influence of alpha- and gamma2- subunits. Brain Res., 784, 179-187.
    • (1998) Brain Res. , vol.784 , pp. 179-187
    • Lam, D.W.1    Reynolds, J.N.2
  • 23
    • 0026684455 scopus 로고
    • The permeation pathway of neurotransmitter-gated ion channels
    • LESTER, H.A. (1992). The permeation pathway of neurotransmitter-gated ion channels. Annu. Rev. Biophys. Biomol. Struct., 21, 267-292.
    • (1992) Annu. Rev. Biophys. Biomol. Struct. , vol.21 , pp. 267-292
    • Lester, H.A.1
  • 26
    • 0027326560 scopus 로고
    • Neuromuscular transmission in nematode parasites and antinematodal drug action
    • MARTIN, R.J. (1993). Neuromuscular transmission in nematode parasites and antinematodal drug action. Pharmacol. Ther., 58, 13-50.
    • (1993) Pharmacol. Ther. , vol.58 , pp. 13-50
    • Martin, R.J.1
  • 27
    • 0020697489 scopus 로고
    • Evidence for similarities between cyclodiene type insecticides and picrotoxinin in their action mechanisms
    • MATSUMURA, F. & GHIASUDDIN, S.M. (1983). Evidence for similarities between cyclodiene type insecticides and picrotoxinin in their action mechanisms. J. Environ. Sci. Health, 18, 1-14.
    • (1983) J. Environ. Sci. Health , vol.18 , pp. 1-14
    • Matsumura, F.1    Ghiasuddin, S.M.2
  • 28
    • 0027200882 scopus 로고
    • The GABAergic nervous system of Caenorhabditis elegans
    • MCINTIRE, S.L., JORGENSEN, E., KAPLAN, J. & HORVITZ, H.R. (1993). The GABAergic nervous system of Caenorhabditis elegans. Nature, 364, 337-341.
    • (1993) Nature , vol.364 , pp. 337-341
    • McIntire, S.L.1    Jorgensen, E.2    Kaplan, J.3    Horvitz, H.R.4
  • 31
    • 0028211208 scopus 로고
    • Dual action of the cyclodiene insecticide dieldrin on the gamma- aminobutyric acid receptor-chloride channel complex of rat dorsal root ganglion neurons
    • NAGATA, K. & NARAHASHI, T. (1994b). Dual action of the cyclodiene insecticide dieldrin on the gamma- aminobutyric acid receptor-chloride channel complex of rat dorsal root ganglion neurons. J. Pharmacol. Exp. Ther., 269, 164-171.
    • (1994) J. Pharmacol. Exp. Ther. , vol.269 , pp. 164-171
    • Nagata, K.1    Narahashi, T.2
  • 32
    • 0033614716 scopus 로고    scopus 로고
    • Sulfated and unsulfated steroids modulate gamma-aminobutyric acidA receptor function through distinct sites
    • PARK-CHUNG, M., MALAYEV, A., PURDY, R.H., GIBBS, T.T. & FARB, D.H. (1999). Sulfated and unsulfated steroids modulate gamma-aminobutyric acidA receptor function through distinct sites. Brain Res., 830, 72-87.
    • (1999) Brain Res. , vol.830 , pp. 72-87
    • Park-Chung, M.1    Malayev, A.2    Purdy, R.H.3    Gibbs, T.T.4    Farb, D.H.5
  • 36
    • 0026451639 scopus 로고
    • The atypical M2 segment of the beta subunit confers picrotoxinin resistance to inhibitory glycine receptor channels
    • PRIBILLA, I., TAKAGI, T., LANGOSCH, D., BORMANN, J. & BETZ, H. (1992). The atypical M2 segment of the beta subunit confers picrotoxinin resistance to inhibitory glycine receptor channels. Embo J., 11, 4305-4311.
    • (1992) Embo J. , vol.11 , pp. 4305-4311
    • Pribilla, I.1    Takagi, T.2    Langosch, D.3    Bormann, J.4    Betz, H.5
  • 37
    • 0025815813 scopus 로고
    • Influence of recombinant gamma-aminobutyric acid-A receptor subunit composition on the action of allosteric modulators of gamma-aminobutyric acid-gated Cl- currents
    • PUIA, G., VICINI, S., SEEBURG, P.H. & COSTA, E. (1991). Influence of recombinant gamma-aminobutyric acid-A receptor subunit composition on the action of allosteric modulators of gamma-aminobutyric acid-gated Cl- currents. Mol. Pharmacol., 39, 691-696.
    • (1991) Mol. Pharmacol. , vol.39 , pp. 691-696
    • Puia, G.1    Vicini, S.2    Seeburg, P.H.3    Costa, E.4
  • 39
    • 0024341942 scopus 로고
    • A chloride channels in mammalian dorsal root ganglion neurones
    • A chloride channels in mammalian dorsal root ganglion neurones. Br. J. Pharmacol., 98, 167-176.
    • (1989) Br. J. Pharmacol. , vol.98 , pp. 167-176
    • Robertson, B.1
  • 40
  • 41
    • 0033178439 scopus 로고    scopus 로고
    • Identification of amino acid residues within GABA(A) receptor beta subunits that mediate both homomeric and heteromeric receptor expression
    • TAYLOR, P.M., THOMAS, P., GORRIE, G.H., CONNOLLY, C.N., SMART, T.G. & MOSS, S.J. (1999). Identification of amino acid residues within GABA(A) receptor beta subunits that mediate both homomeric and heteromeric receptor expression. J. Neurosci., 19, 6360-6371.
    • (1999) J. Neurosci. , vol.19 , pp. 6360-6371
    • Taylor, P.M.1    Thomas, P.2    Gorrie, G.H.3    Connolly, C.N.4    Smart, T.G.5    Moss, S.J.6
  • 42
    • 0027968068 scopus 로고
    • CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
    • THOMPSON, J.D., HIGGINS, D.G. & GIBSON, T.J. (1994). CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic. Acids Res., 22, 4673-4680.
    • (1994) Nucleic. Acids Res. , vol.22 , pp. 4673-4680
    • Thompson, J.D.1    Higgins, D.G.2    Gibson, T.J.3
  • 45
    • 0027018868 scopus 로고
    • Pharmacological profiles of the GABA and acetylcholine receptors from the nematode, Ascaris suum
    • WALKER, R.J., COLQUHOUN, L. & HOLDEN-DYE, L. (1992). Pharmacological profiles of the GABA and acetylcholine receptors from the nematode, Ascaris suum. Acta. Biol. Hung, 43, 59-68.
    • (1992) Acta. Biol. Hung , vol.43 , pp. 59-68
    • Walker, R.J.1    Colquhoun, L.2    Holden-Dye, L.3
  • 46
    • 0029610075 scopus 로고
    • A single amino acid in gamma-aminobutyric acid rho 1 receptors affects competitive and noncompetitive components of picrotoxin inhibition
    • WANG, T.L., HACKAM, A.S., GUGGINO, W.B. & CUTTING, G.R. (1995). A single amino acid in gamma-aminobutyric acid rho 1 receptors affects competitive and noncompetitive components of picrotoxin inhibition. Proc. Natl. Acad. Sci. U.S.A., 92, 11751-11755.
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 11751-11755
    • Wang, T.L.1    Hackam, A.S.2    Guggino, W.B.3    Cutting, G.R.4
  • 48
    • 0028970548 scopus 로고
    • A receptor channel-lining residues probed in cysteine mutants
    • A receptor channel-lining residues probed in cysteine mutants. Biophys. J., 69, 1858-1867.
    • (1995) Biophys. J. , vol.69 , pp. 1858-1867
    • Xu, M.1    Covey, D.F.2    Akabas, M.H.3
  • 49
    • 0023049902 scopus 로고
    • Monogenic inheritance of cyclodiene insecticide resistance in mosquitofish, Gambusia affinis
    • YARBROUGH, J.D., ROUSH, R.T., BONNER, J.C. & WISE, D.A. (1986). Monogenic inheritance of cyclodiene insecticide resistance in mosquitofish, Gambusia affinis. Experientia, 42, 851-853.
    • (1986) Experientia , vol.42 , pp. 851-853
    • Yarbrough, J.D.1    Roush, R.T.2    Bonner, J.C.3    Wise, D.A.4
  • 50
    • 0029417199 scopus 로고
    • Cloning of a gamma-aminobutyric acid type C receptor subunit in rat retina with a methionine residue critical for picrotoxinin channel block
    • ZHANG, D., PAN, Z.H., ZHANG, X., BRIDEAU, A.D. & LIPTON, S.A. (1995). Cloning of a gamma-aminobutyric acid type C receptor subunit in rat retina with a methionine residue critical for picrotoxinin channel block. Proc. Natl. Acad. Sci. U.S.A., 92, 11756-11760.
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 11756-11760
    • Zhang, D.1    Pan, Z.H.2    Zhang, X.3    Brideau, A.D.4    Lipton, S.A.5


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