-
1
-
-
0037062951
-
RNA interference
-
Hannon, G. J. (2002). RNA interference. Nature 418: 244-251.
-
(2002)
Nature
, vol.418
, pp. 244-251
-
-
Hannon, G.J.1
-
2
-
-
0035856381
-
Short 5′-phosphorylated double-stranded RNAs induce RNA interference in Drosophila
-
Boutla, A., Delidakis, C., Livadaras, I., Tsagris, M., and Tabler, M. (2001). Short 5′-phosphorylated double-stranded RNAs induce RNA interference in Drosophila. Curr. Biol. 11: 1776-1780.
-
(2001)
Curr. Biol.
, vol.11
, pp. 1776-1780
-
-
Boutla, A.1
Delidakis, C.2
Livadaras, I.3
Tsagris, M.4
Tabler, M.5
-
3
-
-
0035863097
-
RNA interference is mediated by 21- and 22-nucleatide RNAs
-
Elbashir, S. M., Lendeckel, W., and Tuschl, T. (2001). RNA interference is mediated by 21- and 22-nucleatide RNAs. Genes Dev. 15: 188-200.
-
(2001)
Genes Dev.
, vol.15
, pp. 188-200
-
-
Elbashir, S.M.1
Lendeckel, W.2
Tuschl, T.3
-
4
-
-
0035887005
-
Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans
-
Ketting, R. F., et al. (2001). Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans. Genes Dev. 15: 2654-2659.
-
(2001)
Genes Dev.
, vol.15
, pp. 2654-2659
-
-
Ketting, R.F.1
-
5
-
-
0035929322
-
A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans
-
Knight, S. W., and Bass, B. L. (2001). A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans. Science 293: 2269-2271.
-
(2001)
Science
, vol.293
, pp. 2269-2271
-
-
Knight, S.W.1
Bass, B.L.2
-
6
-
-
0035905766
-
Role for a bidentate ribonuclease in the initiation step of RNA interference
-
Bernstein, E., Caudy, A. A., Hammond, S. M., and Hannon, G. J. (2001). Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 409: 363-366.
-
(2001)
Nature
, vol.409
, pp. 363-366
-
-
Bernstein, E.1
Caudy, A.A.2
Hammond, S.M.3
Hannon, G.J.4
-
7
-
-
0037022382
-
Stable suppression of gene expression by RNAi in mammalian cells
-
Paddison, P. J., Caudy, A. A., and Hannon, G. J. (2002). Stable suppression of gene expression by RNAi in mammalian cells. Proc. Natl. Acad. Sci. USA 99: 1443-1448.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 1443-1448
-
-
Paddison, P.J.1
Caudy, A.A.2
Hannon, G.J.3
-
8
-
-
0033766888
-
Selective reduction of dormant maternal mRNAs in mouse oocytes by RNA interference
-
Svoboda, P., Stein, P., Hayashi, H., and Schultz, R. M. (2000). Selective reduction of dormant maternal mRNAs in mouse oocytes by RNA interference. Development 127: 4147-4156.
-
(2000)
Development
, vol.127
, pp. 4147-4156
-
-
Svoboda, P.1
Stein, P.2
Hayashi, H.3
Schultz, R.M.4
-
9
-
-
0035807818
-
Specific interference with gene expression induced by long, double-stranded RNA in mouse embryonal teratocarcinoma cell lines
-
Billy, E., Brondani, V., Zhang, H., Muller, U., and Filipowicz, W. (2001). Specific interference with gene expression induced by long, double-stranded RNA in mouse embryonal teratocarcinoma cell lines. Proc. Natl. Acad. Sci. USA 98: 14428-14433.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 14428-14433
-
-
Billy, E.1
Brondani, V.2
Zhang, H.3
Muller, U.4
Filipowicz, W.5
-
10
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
Elbashir, S. M., et al. (2001). Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411: 494-498.
-
(2001)
Nature
, vol.411
, pp. 494-498
-
-
Elbashir, S.M.1
-
11
-
-
0035803583
-
Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate
-
Elbashir, S. M., Martinez, J., Patkaniowska, A., Lendeckel, W., and Tuschl, T. (2001). Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate. EMBO J. 20: 6877-6888.
-
(2001)
EMBO J.
, vol.20
, pp. 6877-6888
-
-
Elbashir, S.M.1
Martinez, J.2
Patkaniowska, A.3
Lendeckel, W.4
Tuschl, T.5
-
12
-
-
0037197914
-
RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells
-
Yu, J. Y., DeRuiter, S. L., and Turner, D. L. (2002). RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells. Proc. Natl. Acad. Sci. USA 99: 6047-6052.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 6047-6052
-
-
Yu, J.Y.1
DeRuiter, S.L.2
Turner, D.L.3
-
13
-
-
0012686208
-
A microRNA in a multiple-turnover RNAi enzyme complex
-
Hutvagner, G., and Zamore, P. D. (2002). A microRNA in a multiple-turnover RNAi enzyme complex. Science 1: 1.
-
(2002)
Science
, vol.1
, pp. 1
-
-
Hutvagner, G.1
Zamore, P.D.2
-
14
-
-
0036276110
-
Exon-specific RNKi: A tool for dissecting the functional relevance of alternative splicing
-
Celotto, A. M., and Graveley, B. R. (2002). Exon-specific RNKi: a tool for dissecting the functional relevance of alternative splicing. RNA 8: 718-724.
-
(2002)
RNA
, vol.8
, pp. 718-724
-
-
Celotto, A.M.1
Graveley, B.R.2
-
15
-
-
0036534444
-
Isoform-specific knockdown and expression of adaptor protein ShcA using small interfering RNA
-
Kisielow, M., Kleiner, S., Nagasawa, M., Faisal, A., and Nagamine, Y. (2002). Isoform-specific knockdown and expression of adaptor protein ShcA using small interfering RNA. Biochem. J. 363: 1-5.
-
(2002)
Biochem. J.
, vol.363
, pp. 1-5
-
-
Kisielow, M.1
Kleiner, S.2
Nagasawa, M.3
Faisal, A.4
Nagamine, Y.5
-
16
-
-
0036752955
-
Evidence that siRNAs function as guides, not primers, in the Drosophila and human RNAi pathways
-
Schwarz, D. S., Hutvagner, G., Haley, B., and Zamore, P. D. (2002). Evidence that siRNAs function as guides, not primers, in the Drosophila and human RNAi pathways. Mol. Cell. 10: 537-548.
-
(2002)
Mol. Cell.
, vol.10
, pp. 537-548
-
-
Schwarz, D.S.1
Hutvagner, G.2
Haley, B.3
Zamore, P.D.4
-
17
-
-
0035900635
-
A short primer on RNAi: RNA-directed RNA polymerase acts as a key catalyst
-
Nishikura, K. (2001). A short primer on RNAi: RNA-directed RNA polymerase acts as a key catalyst. Cell 107: 415-418.
-
(2001)
Cell
, vol.107
, pp. 415-418
-
-
Nishikura, K.1
-
18
-
-
0000812508
-
Efficient delivery of siRNA for inhibition of gene expression in postnatal mice
-
Lewis, D. L., Hagstrom, J. E., Loomis, A. G., Wolff, J. A., and Herweijer, H. (2002). Efficient delivery of siRNA for inhibition of gene expression in postnatal mice. Nat. Genet. 29: 29.
-
(2002)
Nat. Genet.
, vol.29
, pp. 29
-
-
Lewis, D.L.1
Hagstrom, J.E.2
Loomis, A.G.3
Wolff, J.A.4
Herweijer, H.5
-
19
-
-
0037019339
-
RNA interference in adult mice
-
McCaffrey, A. P., et al. (2002). RNA interference in adult mice. Nature. 418: 38-39.
-
(2002)
Nature
, vol.418
, pp. 38-39
-
-
McCaffrey, A.P.1
-
20
-
-
0037134020
-
A system for stable expression of short interfering RNAs in mammalian cells
-
Brummelkamp, T. R., Bernards, R., and Agami, R. (2002). A system for stable expression of short interfering RNAs in mammalian cells. Science 296: 550-553.
-
(2002)
Science
, vol.296
, pp. 550-553
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
21
-
-
0037089589
-
Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells
-
Paddison, P. J., Caudy, A. A., Bernstein, E., Hannon, G. J., and Conklin, D. S. (2002). Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells. Genes Dev. 16: 948-958.
-
(2002)
Genes Dev.
, vol.16
, pp. 948-958
-
-
Paddison, P.J.1
Caudy, A.A.2
Bernstein, E.3
Hannon, G.J.4
Conklin, D.S.5
-
22
-
-
0036256430
-
Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells
-
Lee, N. S., et al. (2002). Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells. Nat. Biotechnol. 20: 500-505.
-
(2002)
Nat. Biotechnol.
, vol.20
, pp. 500-505
-
-
Lee, N.S.1
-
23
-
-
0036251639
-
Effective expression of small interfering RNA in human cells
-
Paul, C. P., Good, P. D., Winer, I., and Engelke, D. R. (2002). Effective expression of small interfering RNA in human cells. Nat. Biotechnol. 20: 505-508.
-
(2002)
Nat. Biotechnol.
, vol.20
, pp. 505-508
-
-
Paul, C.P.1
Good, P.D.2
Winer, I.3
Engelke, D.R.4
-
24
-
-
0037117550
-
A DNA vector-based RNAi technology to suppress gene expression in mammalian cells
-
Sui, G., et al. (2002). A DNA vector-based RNAi technology to suppress gene expression in mammalian cells. Proc. Natl. Acad. Sci. USA 99: 5515-5520.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 5515-5520
-
-
Sui, G.1
-
25
-
-
0036245628
-
U6 promoter driven siRNAs with four uridine 3′ overhangs efficiently suppress targeted gene expression in mammalian cells
-
Miyagishi, M., and Taira, K. (2002). U6 promoter driven siRNAs with four uridine 3′ overhangs efficiently suppress targeted gene expression in mammalian cells. Nat. Biotechnol. 20: 497-500.
-
(2002)
Nat. Biotechnol.
, vol.20
, pp. 497-500
-
-
Miyagishi, M.1
Taira, K.2
-
26
-
-
0036294527
-
Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells
-
Zeng, Y., Wagner, E.J., and Cullen, B. R. (2002). Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells. Mol. Cell. 9: 1327-1333.
-
(2002)
Mol. Cell.
, vol.9
, pp. 1327-1333
-
-
Zeng, Y.1
Wagner, E.J.2
Cullen, B.R.3
-
27
-
-
0035800521
-
A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA
-
Hutvagner, G., et al. (2001). A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science 293: 834-838.
-
(2001)
Science
, vol.293
, pp. 834-838
-
-
Hutvagner, G.1
-
28
-
-
0028306459
-
Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate
-
Turner, D. L., and Weintraub, H. (1994). Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate. Genes Dev. 8: 1434-1447.
-
(1994)
Genes Dev.
, vol.8
, pp. 1434-1447
-
-
Turner, D.L.1
Weintraub, H.2
-
29
-
-
0036273940
-
Gene silencing using micro-RNA designed hairpins
-
McManus, M. T., Petersen, C. P., Haines, B. B., Chen, J., and Sharp, P. A. (2002). Gene silencing using micro-RNA designed hairpins. RNA 8: 842-850.
-
(2002)
RNA
, vol.8
, pp. 842-850
-
-
McManus, M.T.1
Petersen, C.P.2
Haines, B.B.3
Chen, J.4
Sharp, P.A.5
-
30
-
-
0035955374
-
Identification of novel genes coding for small expressed RNAs
-
Lagos-Quintana, M., Rauhut, R., Lendeckel, W., and Tuschl, T. (2001). Identification of novel genes coding for small expressed RNAs. Science 294: 853-858.
-
(2001)
Science
, vol.294
, pp. 853-858
-
-
Lagos-Quintana, M.1
Rauhut, R.2
Lendeckel, W.3
Tuschl, T.4
-
31
-
-
0035955361
-
An abundant class of tiny RNAs with probable regulatory roles in Coenorhabditis elegans
-
Lau, N. C., Lim, L. P., Weinstein, E. G., and Bartel, D. P. (2001). An abundant class of tiny RNAs with probable regulatory roles in Coenorhabditis elegans. Science 294: 858-862.
-
(2001)
Science
, vol.294
, pp. 858-862
-
-
Lau, N.C.1
Lim, L.P.2
Weinstein, E.G.3
Bartel, D.P.4
-
32
-
-
0035955366
-
An extensive class of small RNAs in Caenorhabditis elegans
-
Lee, R. C., and Ambros, V. (2001). An extensive class of small RNAs in Caenorhabditis elegans. Science 294: 862-864.
-
(2001)
Science
, vol.294
, pp. 862-864
-
-
Lee, R.C.1
Ambros, V.2
-
33
-
-
0027470177
-
Structure, expression and chromosomal mapping of c-akt: Relationship to v-akt and its implications
-
Bellacosa, A., et al. (1993). Structure, expression and chromosomal mapping of c-akt: relationship to v-akt and its implications. Oncogene 8: 745-754.
-
(1993)
Oncogene
, vol.8
, pp. 745-754
-
-
Bellacosa, A.1
-
34
-
-
0037197803
-
Identification of tissue-specific microRNAs from mouse
-
Lagos-Quintana, M., et al. (2002). Identification of tissue-specific microRNAs from mouse. Curr. Biol. 12: 735-739.
-
(2002)
Curr. Biol.
, vol.12
, pp. 735-739
-
-
Lagos-Quintana, M.1
-
35
-
-
0035909112
-
Judging a protein by more than its name: GSK-3
-
Woodgett, J. R. (2001). Judging a protein by more than its name: GSK-3. Sci STKE. http://stke.sciencemag.org/cgi/content/OC_sigtrons;2001/100/rel12.
-
(2001)
Sci. STKE
-
-
Woodgett, J.R.1
-
36
-
-
0036090823
-
Glycogen synthase kinase 3: An emerging therapeutic target
-
Eldar-Finkelman, H. (2002). Glycogen synthase kinase 3: an emerging therapeutic target. Trends Mol. Med. 8: 126-132.
-
(2002)
Trends Mol. Med.
, vol.8
, pp. 126-132
-
-
Eldar-Finkelman, H.1
-
37
-
-
0033895709
-
Wnt signaling and cancer
-
Polakis, P. (2000). Wnt signaling and cancer. Genes Dev. 14: 1837-1851.
-
(2000)
Genes Dev.
, vol.14
, pp. 1837-1851
-
-
Polakis, P.1
-
38
-
-
0034612636
-
Requirement for glycogen synthase kinase-3β in cell survival and NF-κB activation
-
Hoeflich, K. P., et al. (2000). Requirement for glycogen synthase kinase-3β in cell survival and NF-κB activation. Nature 406: 86-90.
-
(2000)
Nature
, vol.406
, pp. 86-90
-
-
Hoeflich, K.P.1
-
39
-
-
0030449964
-
Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells
-
Stambolic, V., Ruel, L., and Woodgett, J. R. (1996). Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells. Curr. Biol. 6: 1664-1668.
-
(1996)
Curr. Biol.
, vol.6
, pp. 1664-1668
-
-
Stambolic, V.1
Ruel, L.2
Woodgett, J.R.3
-
40
-
-
0033776383
-
Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription
-
Coghlan, M. P., et al. (2000). Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription. Chem. Biol. 7: 793-803.
-
(2000)
Chem. Biol.
, vol.7
, pp. 793-803
-
-
Coghlan, M.P.1
-
41
-
-
0037089135
-
Positional effects of short interfering RNAs targeting the human coagulation trigger tissue factor
-
Holen, T., Amarzguioui, M., Wiiger, M. T., Babaie, E., and Prydz, H. (2002). Positional effects of short interfering RNAs targeting the human coagulation trigger tissue factor. Nucleic Acids Res. 30: 1757-1766.
-
(2002)
Nucleic Acids Res.
, vol.30
, pp. 1757-1766
-
-
Holen, T.1
Amarzguioui, M.2
Wiiger, M.T.3
Babaie, E.4
Prydz, H.5
-
42
-
-
0025286104
-
Molecular cloning and expression of glycogen synthase kinase-3/factor A
-
Woodgett, J. R. (1990). Molecular cloning and expression of glycogen synthase kinase-3/factor A. EMBO J. 9: 2431-2438.
-
(1990)
EMBO J.
, vol.9
, pp. 2431-2438
-
-
Woodgett, J.R.1
-
43
-
-
0029002136
-
A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins
-
Littlewood, T. D., Hancock, D. C., Danielian, P. S., Parker, M. G., and Evan, G. I. (1995). A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins. Nucleic Acids Res. 23: 1686-1690.
-
(1995)
Nucleic Acids Res.
, vol.23
, pp. 1686-1690
-
-
Littlewood, T.D.1
Hancock, D.C.2
Danielian, P.S.3
Parker, M.G.4
Evan, G.I.5
-
44
-
-
0023849463
-
GAL4 activates gene expression in mammalian cells
-
Kakidani, H., and Ptashne, M. (1988). GAL4 activates gene expression in mammalian cells. Cell 52: 161-167.
-
(1988)
Cell
, vol.52
, pp. 161-167
-
-
Kakidani, H.1
Ptashne, M.2
-
45
-
-
0028352113
-
Xenopus embryos regulate the nuclear localization of XMyoD
-
Rupp, R. A., Snider, L., and Weintraub, H. (1994). Xenopus embryos regulate the nuclear localization of XMyoD. Genes Dev. 8: 1311-1323.
-
(1994)
Genes Dev.
, vol.8
, pp. 1311-1323
-
-
Rupp, R.A.1
Snider, L.2
Weintraub, H.3
-
46
-
-
0022596895
-
Expression in mammalian cells of a gene from Streptomyces alboniger conferring puromycin resistance
-
Vara, J. A., Portela, A., Ortin, J., and Jimenez, A. (1986). Expression in mammalian cells of a gene from Streptomyces alboniger conferring puromycin resistance. Nucleic Acids Res. 14: 4617-4624.
-
(1986)
Nucleic Acids Res.
, vol.14
, pp. 4617-4624
-
-
Vara, J.A.1
Portela, A.2
Ortin, J.3
Jimenez, A.4
-
47
-
-
0034051923
-
Generation of neurons by transient expression of neural bHLH proteins in mammalian cells
-
Farah, M. H., et al. (2000). Generation of neurons by transient expression of neural bHLH proteins in mammalian cells. Development 127: 693-702.
-
(2000)
Development
, vol.127
, pp. 693-702
-
-
Farah, M.H.1
|